메뉴 건너뛰기




Volumn 21, Issue 7, 2003, Pages 807-812

Measurement of the millisecond activation switch of G protein-coupled receptors in living cells

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; FLUORESCENCE; HORMONES; NEUROLOGY; PROTEINS; REACTION KINETICS; SIGNAL PROCESSING;

EID: 0038729670     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt838     Document Type: Article
Times cited : (386)

References (26)
  • 1
    • 0031916647 scopus 로고    scopus 로고
    • G protein-coupled receptors: Functional and mechanistic insights through altered gene expression
    • Rohrer, D.K. & Kobilka, B.K. G protein-coupled receptors: functional and mechanistic insights through altered gene expression. Physiol. Rev. 78, 35-52 (1998).
    • (1998) Physiol. Rev. , vol.78 , pp. 35-52
    • Rohrer, D.K.1    Kobilka, B.K.2
  • 2
    • 0034464742 scopus 로고    scopus 로고
    • Uncovering molecular mechanisms involved in activation of G protein-coupled receptor
    • Gether, U. Uncovering molecular mechanisms involved in activation of G protein-coupled receptor. Endocr. Rev. 21, 90-113 (2000).
    • (2000) Endocr. Rev. , vol.21 , pp. 90-113
    • Gether, U.1
  • 4
    • 0029907599 scopus 로고    scopus 로고
    • Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin
    • Farrens, D.L., Altenbach, C., Yang, K., Hubbell, W.L. & Khorana, H.G. Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin. Science 274, 768-770 (1996).
    • (1996) Science , vol.274 , pp. 768-770
    • Farrens, D.L.1    Altenbach, C.2    Yang, K.3    Hubbell, W.L.4    Khorana, H.G.5
  • 5
    • 0029778268 scopus 로고    scopus 로고
    • Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F
    • Sheikh, S.P., Zvyaga, T.A., Lichtarge, O., Sakmar, T.P. & Bourne, H.R. Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F. Nature 383, 347-350 (1996).
    • (1996) Nature , vol.383 , pp. 347-350
    • Sheikh, S.P.1    Zvyaga, T.A.2    Lichtarge, O.3    Sakmar, T.P.4    Bourne, H.R.5
  • 6
    • 0033546197 scopus 로고    scopus 로고
    • 2-adrenoceptor and the parathyroid hormone receptor
    • 2-adrenoceptor and the parathyroid hormone receptor. J. Biol. Chem. 274, 17033-17041 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 17033-17041
    • Sheikh, S.P.1
  • 8
    • 0037127315 scopus 로고    scopus 로고
    • 3 muscarinic acetylcholine receptor activation probed by the use of an in situ disulfide cross-linking strategy
    • 3 muscarinic acetylcholine receptor activation probed by the use of an in situ disulfide cross-linking strategy. J. Biol. Chem. 277, 2247-2257 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 2247-2257
    • Ward, S.D.C.1    Hamdan, F.F.2    Bloodworth, L.M.3    Wess, J.4
  • 9
    • 0035336676 scopus 로고    scopus 로고
    • Activation of rhodopsin: New insights from structural and biochemical studies
    • Okada, T., Ernst, O.P., Palczewski, K. & Hofmann, K.P. Activation of rhodopsin: new insights from structural and biochemical studies. Trends Biochem. Sci. 26, 318-324 (2001).
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 318-324
    • Okada, T.1    Ernst, O.P.2    Palczewski, K.3    Hofmann, K.P.4
  • 10
    • 0028856707 scopus 로고
    • 2-adrenergic receptor: Evidence for ligand-specific conformational changes
    • 2-adrenergic receptor: evidence for ligand-specific conformational changes. J. Biol. Chem. 270, 28268-28275 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 28268-28275
    • Gether, U.1    Lin, S.B.2    Kobilka, K.3
  • 11
    • 0035937786 scopus 로고    scopus 로고
    • 2-adrenergic receptor mapped by site-selective fluorescent labeling
    • 2-adrenergic receptor mapped by site-selective fluorescent labeling. J. Biol. Chem. 276, 9279-9290 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 9279-9290
    • Jensen, A.D.1
  • 12
    • 0035816704 scopus 로고    scopus 로고
    • 2 adrenergic receptor
    • 2 adrenergic receptor. J. Biol. Chem. 276, 24433-24436 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 24433-24436
    • Ghanouni, P.1
  • 14
    • 0033118334 scopus 로고    scopus 로고
    • Molecular tinkering of G protein-coupled receptors: An evolutionary success
    • Bockaert, J. & Pin, J.P. Molecular tinkering of G protein-coupled receptors: an evolutionary success. EMBO J. 18, 1723-1729 (1999).
    • (1999) EMBO J. , vol.18 , pp. 1723-1729
    • Bockaert, J.1    Pin, J.P.2
  • 15
    • 0035823535 scopus 로고    scopus 로고
    • Differential conformational requirements for activation of G proteins and regulatory proteins, arrestin and GRK in the parathyroid hormone receptor
    • Vilardaga, J.P. et al. Differential conformational requirements for activation of G proteins and regulatory proteins, arrestin and GRK in the parathyroid hormone receptor. J. Biol. Chem. 276, 33435-33443 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 33435-33443
    • Vilardaga, J.P.1
  • 16
    • 0031663369 scopus 로고    scopus 로고
    • The green fluorescent protein
    • Tsien, R.Y. The green fluorescent protein. Annu. Rev. Biochem. 67, 509-544 (1998).
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 509-544
    • Tsien, R.Y.1
  • 17
    • 0034581516 scopus 로고    scopus 로고
    • Monitoring protein conformations and interactions by fluorescence resonance energy transfer between mutants of green fluorescent protein
    • Miyawaki, A. & Tsien, R.Y. Monitoring protein conformations and interactions by fluorescence resonance energy transfer between mutants of green fluorescent protein. Methods Enzymol. 327, 472-501 (2000).
    • (2000) Methods Enzymol. , vol.327 , pp. 472-501
    • Miyawaki, A.1    Tsien, R.Y.2
  • 18
    • 0035824582 scopus 로고    scopus 로고
    • 1b-adrenergic receptor
    • 1b-adrenergic receptor. J. Biol. Chem. 276, 46485-46494 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 46485-46494
    • Greasley, P.J.1
  • 20
    • 0035282064 scopus 로고    scopus 로고
    • Selective inactivation of guanine-nucleotide-binding regulatory protein (G-protein) α and βγ subunits by urea
    • Lim, W.J. & Neubig, R.R. Selective inactivation of guanine-nucleotide-binding regulatory protein (G-protein) α and βγ subunits by urea. Biochem. J. 354, 337-344 (2001).
    • (2001) Biochem. J. , vol.354 , pp. 337-344
    • Lim, W.J.1    Neubig, R.R.2
  • 21
    • 0037041007 scopus 로고    scopus 로고
    • Internalization determinants of the parathyroid hormone receptor differentially regulates β-arrestin/receptor association
    • Vilardaga, J.P. et al. Internalization determinants of the parathyroid hormone receptor differentially regulates β-arrestin/receptor association. J. Biol. Chem. 277, 8121-8129 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 8121-8129
    • Vilardaga, J.P.1
  • 22
    • 0036772848 scopus 로고    scopus 로고
    • Dual regulation of the parathyroid hormone (PTH)/PTH-related peptide receptor signaling by protein kinase C and β-arrestins
    • Castro, M. et al. Dual regulation of the parathyroid hormone (PTH)/PTH-related peptide receptor signaling by protein kinase C and β-arrestins. Endocrinology 143, 3854-3865 (2002).
    • (2002) Endocrinology , vol.143 , pp. 3854-3865
    • Castro, M.1
  • 23
    • 0036830645 scopus 로고    scopus 로고
    • Site-specific fluorescence reveals distinct structural changes with GABA receptor activation and antagonism
    • Chang, Y. & Weiss, D.S. Site-specific fluorescence reveals distinct structural changes with GABA receptor activation and antagonism. Nat. Neurosci. 5, 1163-1168 (2002).
    • (2002) Nat. Neurosci. , vol.5 , pp. 1163-1168
    • Chang, Y.1    Weiss, D.S.2
  • 24
    • 0028986215 scopus 로고
    • Improved PCR method for high efficacy site-directed mutagenesis using class 2S restriction enzymes
    • Vilardaga, J.P., di Paolo, E. & Bollen, A. Improved PCR method for high efficacy site-directed mutagenesis using class 2S restriction enzymes. Biotechniques 18, 605-606 (1995).
    • (1995) Biotechniques , vol.18 , pp. 605-606
    • Vilardaga, J.P.1    Di Paolo, E.2    Bollen, A.3
  • 25
    • 0033551693 scopus 로고    scopus 로고
    • Visualization of agonist-induced association and trafficking of green fluorescent protein-tagged forms of both β-arrestin-1 and the thyrotropin-realeasing hormone receptor
    • Groarke, D.A., Wilson, S., Krasel, C. & Milligan, G. Visualization of agonist-induced association and trafficking of green fluorescent protein-tagged forms of both β-arrestin-1 and the thyrotropin-realeasing hormone receptor. J. Biol. Chem. 274, 23263-23269 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 23263-23269
    • Groarke, D.A.1    Wilson, S.2    Krasel, C.3    Milligan, G.4
  • 26
    • 0033531794 scopus 로고    scopus 로고
    • 2A-adrenergic receptor discriminates between Gi heterotrimers of different βγ subunit composition in Sf 9 insect cell membranes
    • 2A-adrenergic receptor discriminates between Gi heterotrimers of different βγ subunit composition in Sf9 insect cell membranes. J. Biol. Chem. 274, 13525-13533 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 13525-13533
    • Richardson, M.1    Robishaw, J.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.