The oligomeric state sets GABA B receptor signalling efficacy

EMBO Journal

Volumn 30, Issue 12, 2011, Pages 2336-2349

  Comps Agrar, Laétitia ^a,b,c   Kniazeff, Julie ^a,b   Nørskov Lauritsen, Lenea ^a,b   Maurel, Damien ^a,b,c   Gassmann, Martin ^d   Gregor, Nathalie ^c   Prézeau, Laurent ^a,b   Bettler, Bernhard ^d   Durroux, Thierry ^a,b   Trinquet, Eric ^c   Pin, Jean Philippe ^a,b  

^a INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

^b UNIV MONTPELLIER   (France)

^c Cisbio   (France)

^d UNIVERSITY OF BASEL   (Switzerland)

Author keywords

cooperativity; GABA; GABAB; GPCR; receptor oligomer

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; OLIGOMER;

ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; COOPERATION; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ALLOSTERIC REGULATION; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; HEK293 CELLS; HUMANS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MUTAGENESIS, SITE-DIRECTED; PROTEIN ISOFORMS; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; RECEPTORS, GABA-B; SIGNAL TRANSDUCTION;

EID: 79958785452     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.143     Document Type: Article

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