Zonated induction of autophagy and mitochondrial spheroids limits acetaminophen-induced necrosis in the liver

Redox Biology

Volumn 1, Issue 1, 2013, Pages 427-432

  Ni, Hong Min ^a   Williams, Jessica A ^a   Jaeschke, Hartmut ^a   Ding, Wen Xing ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Acetaminophen; Autophagy; Liver injury; Mitochondrial spheroid; Mitophagy

Indexed keywords

BECLIN 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PARACETAMOL; PARKIN; PHOSPHATIDYLINOSITOL 3 KINASE;

AUTOPHAGY; BIOGENESIS; CELL EXPANSION; CELLULAR STRESS RESPONSE; HUMAN; LIVER MITOCHONDRION; LIVER NECROSIS; LIVER REGENERATION; MITOPHAGY; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION; SPHEROID CELL; UBIQUITINATION; ANIMAL; CHEMICALLY INDUCED; METABOLISM; MITOCHONDRION; MULTICELLULAR SPHEROID; NECROSIS; PATHOLOGY; TOXIC HEPATITIS;

ACETAMINOPHEN; ANIMALS; AUTOPHAGY; DRUG-INDUCED LIVER INJURY; HUMANS; MITOCHONDRIA; NECROSIS; SPHEROIDS, CELLULAR;

EID: 84883763522     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2013.08.005     Document Type: Review

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