P53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia

Journal of Molecular and Cellular Cardiology

Volumn 52, Issue 1, 2012, Pages 175-184

  Hoshino, Atsushi ^a   Matoba, Satoaki ^a   Iwai Kanai, Eri ^a,b   Nakamura, Hideo ^a   Kimata, Masaki ^a   Nakaoka, Mikihiko ^a   Katamura, Maki ^a   Okawa, Yoshifumi ^a   Ariyoshi, Makoto ^a   Mita, Yuichiro ^a   Ikeda, Koji ^a   Ueyama, Tomomi ^a   Okigaki, Mitsuhiko ^a   Matsubara, Hiroaki ^a  

^a KYOTO PREFECTURAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b MEIJI UNIVERSITY OF INTEGRATIVE MEDICINE   (Japan)

Author keywords

Autophagy; Mitochondria; Myocardial infarction; P53; Remodeling

Indexed keywords

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; CHLOROQUINE; PROTEIN BNIP3; PROTEIN P53; REACTIVE OXYGEN METABOLITE; REGULATOR PROTEIN; TP53 INDUCED GLYCOLYSIS AND APOPTOSIS REGULATOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; ELECTRON MICROSCOPY; HEART INFARCTION; HEART MITOCHONDRION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MITOPHAGY; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; APOPTOSIS; AUTOPHAGY; GENE EXPRESSION REGULATION; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA, HEART; MITOCHONDRIAL PROTEINS; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; OXIDATIVE STRESS; PROTEINS; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEIN P53; VENTRICULAR REMODELING;

MUS;

EID: 84155180848     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2011.10.008     Document Type: Article

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