Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis

Oncogene

Volumn 24, Issue 27, 2005, Pages 4421-4432

  Erkan, Mert ^a   Kleeff, Jörg ^a   Esposito, Irene ^a   Giese, Thomas ^a   Ketterer, Knut ^a   Büchler, Markus W ^a   Giese, Nathalla A ^a   Friess, Helmut ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Apoptosis; Bcl 2; Chemoresistance; Hypoxia; PanIN; TGF beta

Indexed keywords

3 (4,5 METHYLTHIAZOL 2 YL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTIINFECTIVE AGENT; BROMINE DERIVATIVE; COMPLEMENTARY DNA; FLUOROURACIL; GEMCITABINE; MESSENGER RNA; PROTEIN BNIP3; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; BNIP3 PROTEIN, HUMAN; DEOXYCYTIDINE; DRUG DERIVATIVE; MEMBRANE PROTEIN; ONCOPROTEIN;

ACINAR CELL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER SURVIVAL; CHRONIC PANCREATITIS; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LASER CAPTURE MICRODISSECTION; PANCREAS CANCER; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; CANCER STAGING; DRUG EFFECT; DRUG RESISTANCE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PANCREAS TUMOR; PATHOLOGY; SURVIVAL RATE; TUMOR CELL LINE;

CELL LINE, TUMOR; DEOXYCYTIDINE; DRUG RESISTANCE, NEOPLASM; FLUOROURACIL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MEMBRANE PROTEINS; NEOPLASM STAGING; PANCREATIC NEOPLASMS; PROGNOSIS; PROTO-ONCOGENE PROTEINS; RNA, MESSENGER; RNA, SMALL INTERFERING; SURVIVAL RATE;

EID: 21744434389     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208642     Document Type: Article

References (61)

1. Adams JM and Cory S. (1998). Science, 281, 1322-1326.
2. Bacon AL and Harris AL. (2004). Ann. Med., 36, 530-539.
3. Bani MR, Nicoletti MI, Alkharouf NW, Ghilardi C, Petersen D, Erba E, Sausville EA, Liu ET and Giavazzi R. (2004). Mol. Cancer Ther., 3, 111-121.
4. Bold RJ, Chandra J and McConkey DJ. (1999). Ann. Surg. Oncol., 6, 279-285.
5. Brandt R, Grutzmann R, Bauer A, Jesnowski R, Ringel J, Lohr M, Pilarsky C and Hoheisel JD. (2004). Pancreatology, 4, 587-597.
6. Bruick RK. (2000). Proc. Natl. Acad. Sci. USA, 97, 9082-9087.
7. Burris III HA, Moore MJ, Andersen J, Green MR, Rothenberg ML, Modiano MR, Cripps MC, Portenoy RK, Storniolo AM, Tarassoff P, Nelson R, Dorr FA, Stephens CD and Von Hoff DD. (1997). J. Clin. Oncol., 15, 2403-2413.
8. Chen G, Cizeau J, Vande Velde C, Park JH, Bozek G, Bolton J, Shi L, Dubik D and Greenberg A. (1999). J. Biol. Chem., 274, 7-10.
9. Chen G, Ray R, Dubik D, Shi L, Cizeau J, Bleackley RC, Saxena S, Gietz RD and Greenberg AH. (1997). J. Exp. Med., 186, 1975-1983.
10. Crnogorac-Jurcevic T, Efthimiou E, Nielsen T, Loader J, Terris B, Stamp G, Baron A, Scarpa A and Lemoine NR. (2002). Oncogene, 21, 4587-4594.
11. Crown J, Casper ES, Botet J, Murray P and Kelsen DP. (1991). J. Clin. Oncol., 9, 1682-1686.
12. Cullinan S, Moertel CG, Wieand HS, Schutt AJ, Krook JE, Foley JF, Norris BD, Kardinal CG, Tschetter LK and Barlow JF. (1990). Cancer, 65, 2207-2212.
13. Daido S, Kanzawa T, Yamamoto A, Takeuchi H, Kondo Y and Kondo S. (2004). Cancer Res., 64, 4286-4293.
14. de Angelis PM, Fjell B, Kravik KL, Haug T, Tunheim SH, Reichelt W, Beigi M, Clausen OP, Galteland E and Stokke T. (2004). Int. J. Oncol., 24, 1279-1288.
15. Friess H, Buchler MW, Mueller C and Malfertheiner P. (1998a). Gastroenterology, 115, 1018-1022.
16. Friess H, Ding J, Kleeff J, Fenkell L, Rosinski JA, Guweidhi A, Reidhaar-Olson JF, Korc M, Hammer J and Buchler MW. (2003). Cell Mol. Life Sci., 60, 1180-1199.
17. Friess H, Lu Z, Graber HU, Zimmermann A, Adler G, Korc M, Schmid RM and Buchler MW. (1998b). Gut, 43, 414-421.
18. Giatromanolaki A, Koukourakis MI, Sowter HM, Sivridis E, Gibson S, Gatter KC and Harris AL. (2004). Clin. Cancer Res., 10, 5566-5571.
19. Graber HU, Friess H, Zimmermann A, Korc M, Adler G, Schmid R and Buchler MW. (1999). J. Gastrointest. Surg., 3, 74-80; discussion 81.
20. Graeber TG, Osmanian C, Jacks T, Housman DE, Koch CJ, Lowe SW and Giaccia AJ. (1996). Nature, 379, 88-91.
21. Graham RM, Frazier DP, Thompson JW, Haliko S, Li H, Wasserlauf BJ, Spiga MG, Bishopric NH and Webster KA. (2004). J. Exp. Biol., 207, 3189-3200.
22. Greijer AE and van der Wall E. (2004). J. Clin. Pathol., 57, 1009-1014.
23. Guo J, Kleeff J, Li J, Ding J, Hammer J, Zhao Y, Giese T, Korc M, Buchler MW and Friess H. (2004). Oncogene, 23, 71-81.
24. Hanahan D and Weinberg RA. (2000). Cell, 100, 57-70.
25. Harris AL. (2002). Nat. Rev. Cancer, 2, 38-47.
26. Imazu T, Shimizu S, Tagami S, Matsushima M, Nakamura Y, Miki T, Okuyama A and Tsujimoto Y. (1999). Oncogene, 18, 4523-4529.
27. Kennedy AS, Harrison GH, Mansfield CM, Zhou XJ, Xu JF and Balcer-Kubiczek EK. (2000). Int. J. Cancer, 90, 175-185.
28. Kerr JF, Winterford CM and Harmon BV. (1994). Cancer, 73, 2013-2026.
29. Ketterer K, Rao S, Friess H, Weiss J, Buchler MW and Korc M. (2003). Clin. Cancer Res., 9, 5127-5136.
30. Kleeff J, Friess H, Simon P, Susmallian S, Buchler P, Zimmermann A, Buchler MW and Korc M. (1999a). Digest. Dis. Sci., 44, 1793-1802.
31. Kleeff J, Ishiwata T, Maruyama H, Friess H, Truong P, Buchler MW, Falb D and Korc M. (1999b). Oncogene, 18, 5363-5372.
32. Kleeff J, Maruyama H, Friess H, Buchler MW, Falb D and Korc M. (1999c). Biochem. Biophys. Res. Commun., 255, 268-273.
33. Klinkenbijl JH, Jeekel J, Sahmoud T, van Pel R, Couvreur ML, Veenhof CH, Arnaud JP, Gonzalez DG, de Wit LT, Hennipman A and Wils J. (1999). Ann. Surg., 230, 776-782; discussion 782-784.
34. Koong AC, Mehta VK, Le QT, Fisher GA, Terris DJ, Brown JM, Bastidas AJ and Vierra M. (2000). Int. J. Radiat. Oncol. Biol. Phys., 48, 919-922.
35. Korsmeyer SJ. (1992). Blood, 80, 879-886.
36. Kothari S, Cizeau J, McMillan-Ward E, Israels SJ, Bailes M, Ens K, Kirshenbaum LA and Gibson SB. (2003). Oncogene, 22, 4734-4744.
37. Lamy L, Ticchioni M, Rouquette-Jazdanian AK, Samson M, Deckert M, Greenberg AH and Bernard A. (2003). J. Biol. Chem., 278, 23915-23921.
38. Monti P, Marchesi F, Reni M, Mercalli A, Sordi V, Zerbi A, Balzano G, Di Carlo V, Allavena P and Piemonti L. (2004). Virchows Arch., 445, 236-247.
39. Moskaluk CA, Hruban RH and Kern SE. (1997). Cancer Res., 57, 2140-2143.
40. Neoptolemos JP, Stocken DD, Friess H, Bassi C, Dunn JA, Hickey H, Beger H, Fernandez-Cruz L, Dervenis C, Lacaine F, Falconi M, Pederzoli P, Pap A, Spooner D, Kerr DJ and Buchler MW. (2004). N. Engl. J. Med., 350, 1200-1210.
41. Okami J, Simeone DM and Logsdon CD. (2004). Cancer Res., 64, 5338-5346.
42. Ray R, Chen G, Vande Velde C, Cizeau J, Park JH, Reed JC, Gietz RD and Greenberg AH. (2000). J. Biol. Chem., 275, 1439-1448.
43. Reynolds TY, Rockwell S and Glazer PM. (1996). Cancer Res., 56, 5754-5757.
44. Richter A, Niedergethmann M, Sturm JW, Lorenz D, Post S and Trede M. (2003). World J. Surg., 27, 324-329.
45. Schmaltz C, Hardenbergh PH, Wells A and Fisher DE. (1998). Mol. Cell. Biol., 18, 2845-2854.
46. Schmidt-Kastner R, Aguirre-Chen C, Kietzmann T, Saul I, Busto R and Ginsberg MD. (2004). Brain Res., 1001, 133-142.
47. Shi X, Liu S, Kleeff J, Friess H and Buchler MW. (2002). Oncology, 62, 354-362.
48. Sowter HM, Ferguson M, Pym C, Watson P, Fox SB, Han C and Harris AL. (2003). J. Pathol., 201, 573-580.
49. Sowter HM, Ratcliffe PJ, Watson P, Greenberg AH and Harris AL. (2001). Cancer Res., 61, 6669-6673.
50. Takaori K, Hruban RH, Maitra A and Tanigawa N. (2004). Pancreas, 28, 257-262.
51. Tenedini E, Fagioli ME, Vianelli N, Tazzari PL, Ricci F, Tagliafico E, Ricci P, Gugliotta L, Martinelli G, Tura S, Baccarani M, Ferrari S and Catani L. (2004). Blood, 104, 3126-3135.
52. Tracey L, Spiteri I, Ortiz P, Lawler M, Piris MA and Villuendas R. (2004). J. Interferon Cytokine Res., 24, 185-195.
53. Vande Velde C, Cizeau J, Dubik D, Alimonti J, Brown T, Israels S, Hakem R and Greenberg AH. (2000). Mol. Cell. Biol., 20, 5454-5468.
54. Wagner M, Redaelli C, Lietz M, Seiler CA, Friess H and Buchler MW. (2004). Br. J. Surg., 91, 586-594.
55. Warshaw AL and Fernandez-del Castillo C. (1992). N. Engl. J. Med., 326, 455-465.
56. White E. (1996). Genes Dev., 10, 1-15.
57. Wilentz RE, Iacobuzio-Donahue CA, Argani P, McCarthy DM, Parsons JL, Yeo CJ, Kern SE and Hruban RH. (2000). Cancer Res., 60, 2002-2006.
58. Xu ZW, Friess H, Buchler MW and Solioz M. (2002). Cancer Chemother. Pharmacol., 49, 504-510.
59. Yasuda M, Theodorakis P, Subramanian T and Chinnadurai G. (1998). J. Biol. Chem., 273, 12415-12421.
60. Yeo CJ, Cameron JL, Sohn TA, Lillemoe KD, Pitt HA, Talamini MA, Hruban RH, Ord SE, Sauter PK, Coleman J, Zahurak ML, Grochow LB and Abrams RA. (1997). Ann. Surg., 226, 248-257; discussion 257-260.
61. Yook YH, Kang KH, Maeng O, Kim TR, Lee JO, Kang KI, Kim YS, Paik SG and Lee H. (2004). Biochem. Biophys. Res. Commun., 321, 298-305.