-
1
-
-
33750459730
-
Parkinsonism genes: Culprits and clues
-
DOI 10.1111/j.1471-4159.2006.04102.x
-
Abeliovich A, Flint Beal M (2006). Parkinsonism genes: culprits and clues. J Neurochem 99, 1062-1072. (Pubitemid 44655273)
-
(2006)
Journal of Neurochemistry
, vol.99
, Issue.4
, pp. 1062-1072
-
-
Abeliovich, A.1
Flint Beal, M.2
-
2
-
-
17644365438
-
Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability
-
DOI 10.1073/pnas.0500617102
-
Beilina A, Van Der Brug M, Ahmad R, Kesavapany S, Miller DW, Petsko GA, Cookson MR (2005). Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability. Proc Natl Acad Sci USA102, 5703-5708. (Pubitemid 40559623)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.16
, pp. 5703-5708
-
-
Beilina, A.1
Van Der Brug, M.2
Ahmad, R.3
Kesavapany, S.4
Miller, D.W.5
Petsko, G.A.6
Cookson, M.R.7
-
3
-
-
38949205955
-
SARM: A novel Toll-like receptor adaptor, is functionally conserved from arthropod to human
-
DOI 10.1016/j.molimm.2007.09.030, PII S016158900700781X
-
Belinda LW, Wei WX, Hanh BT, Lei LX, Bow H, Ling DJ (2008). SARM: a novel Toll-like receptor adaptor, is functionally conserved from arthropod to human. Mol Immunol 45, 1732-1742. (Pubitemid 351221135)
-
(2008)
Molecular Immunology
, vol.45
, Issue.6
, pp. 1732-1742
-
-
Belinda, L.W.-C.1
Wei, W.X.2
Hanh, B.T.H.3
Lei, L.X.4
Bow, H.5
Ling, D.J.6
-
4
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
DOI 10.1126/science.1077209
-
Bonifati V et al. (2003). Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 299, 256-259. (Pubitemid 36131051)
-
(2003)
Science
, vol.299
, Issue.5604
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
Van Baren, M.J.3
Schaap, O.4
Breedveld, G.J.5
Krieger, E.6
Dekker, M.C.J.7
Squitieri, F.8
Ibanez, P.9
Joosse, M.10
Van Dongen, J.W.11
Vanacore, N.12
Van Swieten, J.C.13
Brice, A.14
Meco, G.15
Van Duijn, C.M.16
Oostra, B.A.17
Heutink, P.18
-
5
-
-
22044432781
-
Early-onset parkinsonism associated with PINK1 mutations: Frequency, genotypes, and phenotypes
-
DOI 10.1212/01.wnl.0000167546.39375.82
-
Bonifati V et al. (2005). Early-onset parkinsonism associated with PINK1 mutations: frequency, genotypes, and phenotypes. Neurology 65, 87-95. (Pubitemid 40967781)
-
(2005)
Neurology
, vol.65
, Issue.1
, pp. 87-95
-
-
Bonifati, V.1
Rohe, C.F.2
Breedveld, G.J.3
Fabrizio, E.4
De Mari, M.5
Tassorelli, C.6
Tavella, A.7
Marconi, R.8
Nicholl, D.J.9
Chien, H.F.10
Fincati, E.11
Abbruzzese, G.12
Marini, P.13
De Gaetano, A.14
Horstink, M.W.15
Maat-Kievit, J.A.16
Sampaio, C.17
Antonini, A.18
Stocchi, F.19
Montagna, P.20
Toni, V.21
Guidi, M.22
Dalla Libera, A.23
Tinazzi, M.24
De Pandis, F.25
Fabbrini, G.26
Goldwurm, S.27
De Klein, A.28
Barbosa, E.29
Lopiano, L.30
Martignoni, E.31
Lamberti, P.32
Vanacore, N.33
Meco, G.34
Oostra, B.A.35
more..
-
6
-
-
0029761275
-
TRAF6 is a signal transducer for interleukin-1
-
DOI 10.1038/383443a0
-
Cao Z, Xiong J, Takeuchi M, Kurama T, Goeddel DV (1996). TRAF6 is a signal transducer for interleukin-1. Nature 383, 443-446. (Pubitemid 26330834)
-
(1996)
Nature
, vol.383
, Issue.6599
, pp. 443-446
-
-
Cao, Z.1
Xiong, J.2
Takeuchi, M.3
Kurama, T.4
Goeddel, D.V.5
-
7
-
-
79954520907
-
Broad activation of the ubiquitin-proteasome system by parkin is critical for mitophagy
-
Chan NC, Salazar AM, Pham AH, Sweredoski MJ, Kolawa NJ, Graham RL, Hess S, Chan DC (2011). Broad activation of the ubiquitin-proteasome system by parkin is critical for mitophagy. Hum Mol Genet 20, 1726-1737.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 1726-1737
-
-
Chan, N.C.1
Salazar, A.M.2
Pham, A.H.3
Sweredoski, M.J.4
Kolawa, N.J.5
Graham, R.L.6
Hess, S.7
Chan, D.C.8
-
8
-
-
79960817201
-
Microtubule-based localization of a synaptic calcium-signaling complex is required for left-right neuronal asymmetry in C. Elegans
-
Chang C, Hsieh YW, Lesch BJ, Bargmann CI, Chuang CF (2011). Microtubule-based localization of a synaptic calcium-signaling complex is required for left-right neuronal asymmetry in C. elegans. Development 138, 3509-3518.
-
(2011)
Development
, vol.138
, pp. 3509-3518
-
-
Chang, C.1
Hsieh, Y.W.2
Lesch, B.J.3
Bargmann, C.I.4
Chuang, C.F.5
-
9
-
-
79958191516
-
Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology
-
Chen CY, Lin CW, Chang CY, Jiang ST, Hsueh YP (2011). Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology. J Cell Biol 193, 769-784.
-
(2011)
J Cell Biol
, vol.193
, pp. 769-784
-
-
Chen, C.Y.1
Lin, C.W.2
Chang, C.Y.3
Jiang, S.T.4
Hsueh, Y.P.5
-
10
-
-
12144283454
-
A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling
-
DOI 10.1101/gad.1276505
-
Chuang CF, Bargmann CI (2005). A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling. Genes Dev 19, 270-281. (Pubitemid 40111122)
-
(2005)
Genes and Development
, vol.19
, Issue.2
, pp. 270-281
-
-
Chuang, C.-F.1
Bargmann, C.I.2
-
11
-
-
33745589773
-
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
-
DOI 10.1038/nature04779, PII N04779
-
Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, Seol JH, Yoo SJ, Hay BA, Guo M (2006). Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 441, 1162-1166. (Pubitemid 43990738)
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1162-1166
-
-
Clark, I.E.1
Dodson, M.W.2
Jiang, C.3
Cao, J.H.4
Huh, J.R.5
Seol, J.H.6
Yoo, S.J.7
Hay, B.A.8
Guo, M.9
-
12
-
-
33748351613
-
PINK1 homozygous W437X mutation in a patient with apparent dominant transmission of Parkinsonism
-
DOI 10.1002/mds.20933
-
Criscuolo C et al. (2006). PINK1 homozygous W437X mutation in a patient with apparent dominant transmission of parkinsonism. Mov Disord 21, 1265-1267. (Pubitemid 44336626)
-
(2006)
Movement Disorders
, vol.21
, Issue.8
, pp. 1265-1267
-
-
Criscuolo, C.1
Volpe, G.2
De Rosa, A.3
Varrone, A.4
Marongiu, R.5
Mancini, P.6
Salvatore, E.7
Dallapiccola, B.8
Filla, A.9
Valente, E.M.10
De Michele, G.11
-
13
-
-
38449116840
-
Studies of SARM1 uncover similarities between immune and neuronal responses to danger
-
Dalod M (2007). Studies of SARM1 uncover similarities between immune and neuronal responses to danger. Sci STKE 2007, pe73.
-
(2007)
Sci STKE
, vol.2007
-
-
Dalod, M.1
-
14
-
-
79551574736
-
PINK1 cleavage at position A103 by the mitochondrial protease PARL
-
Deas E et al. (2011). PINK1 cleavage at position A103 by the mitochondrial protease PARL. Hum Mol Genet 20, 867-879.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 867-879
-
-
Deas, E.1
-
15
-
-
27144469287
-
Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y
-
DOI 10.1016/j.bbrc.2005.09.178, PII S0006291X05022205
-
Deng H, Jankovic J, Guo Y, Xie W, Le W (2005). Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y. Biochem Biophys Res Commun 337, 1133-1138. (Pubitemid 41505244)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.337
, Issue.4
, pp. 1133-1138
-
-
Deng, H.1
Jankovic, J.2
Guo, Y.3
Xie, W.4
Le, W.5
-
16
-
-
33745087689
-
PINK1 protein in normal human brain and Parkinson's disease
-
DOI 10.1093/brain/awl114
-
Gandhi S et al. (2006). PINK1 protein in normal human brain and Parkinson's disease. Brain 129, 1720-1731. (Pubitemid 43999406)
-
(2006)
Brain
, vol.129
, Issue.7
, pp. 1720-1731
-
-
Gandhi, S.1
Muqit, M.M.K.2
Stanyer, L.3
Healy, D.G.4
Abou-Sleiman, P.M.5
Hargreaves, I.6
Heales, S.7
Ganguly, M.8
Parsons, L.9
Lees, A.J.10
Latchman, D.S.11
Holton, J.L.12
Wood, N.W.13
Revesz, T.14
-
17
-
-
78649463381
-
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
-
Gegg ME, Cooper JM, Chau KY, Rojo M, Schapira AH, Taanman JW (2010). Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy. Hum Mol Genet 19, 4861-4870.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4861-4870
-
-
Gegg, M.E.1
Cooper, J.M.2
Chau, K.Y.3
Rojo, M.4
Schapira, A.H.5
Taanman, J.W.6
-
18
-
-
75949130828
-
PINK1/parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
Geisler S, Holmstrom KM, Skujat D, Fiesel FC, Rothfuss OC, Kahle PJ, Springer W (2010). PINK1/parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat Cell Biol 12, 119-131.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmstrom, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
Springer, W.7
-
19
-
-
79960493052
-
Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1
-
Glauser L, Sonnay S, Stafa K, Moore DJ (2011). Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1. J Neurochem 118, 636-645.
-
(2011)
J Neurochem
, vol.118
, pp. 636-645
-
-
Glauser, L.1
Sonnay, S.2
Stafa, K.3
Moore, D.J.4
-
20
-
-
84859428688
-
Mitochondrial processing peptidase regulates PINK1 processing, import and parkin recruitment
-
Greene AW, Grenier K, Aguileta MA, Muise S, Farazifard R, Haque ME, McBride HM, Park DS, Fon EA (2012). Mitochondrial processing peptidase regulates PINK1 processing, import and parkin recruitment. EMBO Rep 13, 378-385.
-
(2012)
EMBO Rep
, vol.13
, pp. 378-385
-
-
Greene, A.W.1
Grenier, K.2
Aguileta, M.A.3
Muise, S.4
Farazifard, R.5
Haque, M.E.6
McBride, H.M.7
Park, D.S.8
Fon, E.A.9
-
21
-
-
39449098267
-
Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP
-
DOI 10.1073/pnas.0705363105
-
Haque ME, Thomas KJ, D'Souza C, Callaghan S, Kitada T, Slack RS, Fraser P, Cookson MR, Tandon A, Park DS (2008). Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP. Proc Natl Acad Sci USA105, 1716-1721. (Pubitemid 351346580)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.5
, pp. 1716-1721
-
-
Haque, M.E.1
Thomas, K.J.2
D'Souza, C.3
Callaghan, S.4
Kitada, T.5
Slack, R.S.6
Fraser, P.7
Cookson, M.R.8
Tandon, A.9
Park, D.S.10
-
22
-
-
33750594065
-
Genetics of Parkinson's disease and parkinsonism
-
DOI 10.1002/ana.21022
-
Hardy J, Cai H, Cookson MR, Gwinn-Hardy K, Singleton A (2006). Genetics of Parkinson's disease and parkinsonism. Ann Neurol 60, 389-398. (Pubitemid 44684974)
-
(2006)
Annals of Neurology
, vol.60
, Issue.4
, pp. 389-398
-
-
Hardy, J.1
Cai, H.2
Cookson, M.R.3
Gwinn-Hardy, K.4
Singleton, A.5
-
23
-
-
4344681293
-
Pathogenetic mechanisms of parkin in Parkinson's disease
-
DOI 10.1016/S0140-6736(04)16901-8, PII S0140673604169018
-
Hattori N, Mizuno Y (2004). Pathogenetic mechanisms of parkin in Parkinson's disease. Lancet 364, 722-724. (Pubitemid 39140630)
-
(2004)
Lancet
, vol.364
, Issue.9435
, pp. 722-724
-
-
Hattori, N.1
Mizuno, P.Y.2
-
24
-
-
0033525582
-
Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair
-
Hofmann RM, Pickart CM (1999). Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair. Cell 96, 645-653. (Pubitemid 29122807)
-
(1999)
Cell
, vol.96
, Issue.5
, pp. 645-653
-
-
Hofmann, R.M.1
Pickart, C.M.2
-
25
-
-
0030032106
-
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
-
DOI 10.1016/S0092-8674(00)80984-8
-
Hsu H, Shu HB, Pan MG, Goeddel DV (1996). TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 84, 299-308. (Pubitemid 26042835)
-
(1996)
Cell
, vol.84
, Issue.2
, pp. 299-308
-
-
Hsu, H.1
Shu, H.-B.2
Pan, M.-G.3
Goeddel, D.V.4
-
26
-
-
78649685455
-
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
-
Jin SM, Lazarou M, Wang C, Kane LA, Narendra DP, Youle RJ (2010). Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL. J Cell Biol 191, 933-942.
-
(2010)
J Cell Biol
, vol.191
, pp. 933-942
-
-
Jin, S.M.1
Lazarou, M.2
Wang, C.3
Kane, L.A.4
Narendra, D.P.5
Youle, R.J.6
-
27
-
-
25144433763
-
Dopaminergic function in a family with the PARK6 form of autosomal recessive Parkinson's syndrome
-
DOI 10.1007/s00702-005-0281-9
-
Kessler KR, Hamscho N, Morales B, Menzel C, Barrero F, Vives F, Gispert S, Auburger G (2005). Dopaminergic function in a family with the PARK6 form of autosomal recessive Parkinson's syndrome. J Neural Transm 112, 1345-1353. (Pubitemid 41355962)
-
(2005)
Journal of Neural Transmission
, vol.112
, Issue.10
, pp. 1345-1353
-
-
Kessler, K.R.1
Hamscho, N.2
Morales, B.3
Menzel, C.4
Barrero, F.5
Vives, F.6
Gispert, S.7
Auburger, G.8
-
28
-
-
34548424488
-
MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival
-
DOI 10.1084/jem.20070868
-
Kim Y, Zhou P, Qian L, Chuang JZ, Lee J, Li C, Iadecola C, Nathan C, Ding A (2007). MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival. J Exp Med 204, 2063-2074. (Pubitemid 47360869)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.9
, pp. 2063-2074
-
-
Kim, Y.1
Zhou, P.2
Qian, L.3
Chuang, J.-Z.4
Lee, J.5
Li, C.6
Iadecola, C.7
Nathan, C.8
Ding, A.9
-
29
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
DOI 10.1038/33416
-
Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, Minoshima S, Yokochi M, Mizuno Y, Shimizu N (1998). Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392, 605-608. (Pubitemid 28207717)
-
(1998)
Nature
, vol.392
, Issue.6676
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
30
-
-
84864267876
-
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates parkin E3 ligase activity by phosphorylating serine 65
-
Kondapalli C et al. (2012). PINK1 is activated by mitochondrial membrane potential depolarization and stimulates parkin E3 ligase activity by phosphorylating serine 65. Open Biol 2, 120080.
-
(2012)
Open Biol
, vol.2
, pp. 120080
-
-
Kondapalli, C.1
-
31
-
-
33947506493
-
Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of IκB kinase activation
-
DOI 10.1074/jbc.M609503200
-
Lamothe B, Besse A, Campos AD, Webster WK, Wu H, Darnay BG (2007). Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation. J Biol Chem 282, 4102-4112. (Pubitemid 47084488)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.6
, pp. 4102-4112
-
-
Lamothe, B.1
Besse, A.2
Campos, A.D.3
Webster, W.K.4
Wu, H.5
Darnay, B.G.6
-
32
-
-
84857032953
-
Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase parkin
-
Lazarou M, Jin SM, Kane LA, Youle RJ (2012). Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase parkin. Dev Cell 22, 320-333.
-
(2012)
Dev Cell
, vol.22
, pp. 320-333
-
-
Lazarou, M.1
Jin, S.M.2
Kane, L.A.3
Youle, R.J.4
-
33
-
-
84866348798
-
PINK1 stimulates interleukin-1beta-mediated inflammatory signaling via the positive regulation of TRAF6 and TAK1
-
Lee HJ, Jang SH, Kim H, Yoon JH, Chung KC (2012). PINK1 stimulates interleukin-1beta-mediated inflammatory signaling via the positive regulation of TRAF6 and TAK1. Cell Mol Life Sci 69, 3301-3315.
-
(2012)
Cell Mol Life Sci
, vol.69
, pp. 3301-3315
-
-
Lee, H.J.1
Jang, S.H.2
Kim, H.3
Yoon, J.H.4
Chung, K.C.5
-
34
-
-
2342475724
-
Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response
-
DOI 10.1073/pnas.0308625101
-
Liberati NT, Fitzgerald KA, Kim DH, Feinbaum R, Golenbock DT, Ausubel FM (2004). Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response. Proc Natl Acad Sci USA101, 6593-6598. (Pubitemid 38586019)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.17
, pp. 6593-6598
-
-
Liberati, N.T.1
Fitzgerald, K.A.2
Kim, D.H.3
Feinbaum, R.4
Golenbock, D.T.5
Ausubel, F.M.6
-
35
-
-
4444258208
-
Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-κB activation by Toll-like receptor (TLR)-2 and TLR4
-
DOI 10.1074/jbc.C400289200
-
Mansell A, Brint E, Gould JA, O'Neill LA, Hertzog PJ (2004). Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kappaB activation by toll-like receptor (TLR)-2 and TLR4. J Biol Chem 279, 37227-37230. (Pubitemid 39195427)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.36
, pp. 37227-37230
-
-
Mansell, A.1
Brint, E.2
Gould, J.A.3
O'Neill, L.A.4
Hertzog, P.J.5
-
36
-
-
77951181836
-
PINK1 stabilized by mitochondrial depolarization recruits parkin to damaged mitochondria and activates latent parkin for mitophagy
-
Matsuda N et al. (2010). PINK1 stabilized by mitochondrial depolarization recruits parkin to damaged mitochondria and activates latent parkin for mitophagy. J Cell Biol 189, 211-221.
-
(2010)
J Cell Biol
, vol.189
, pp. 211-221
-
-
Matsuda, N.1
-
37
-
-
0347480221
-
Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish
-
DOI 10.1016/j.molimm.2003.10.003
-
Meijer AH, Gabby Krens SF, Medina Rodriguez IA, He S, Bitter W, Ewa Snaar-Jagalska B, Spaink HP (2004). Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish. Mol Immunol 40, 773-783. (Pubitemid 37542427)
-
(2004)
Molecular Immunology
, vol.40
, Issue.11
, pp. 773-783
-
-
Meijer, A.H.1
Gabby Krens, S.F.2
Medina Rodriguez, I.A.3
He, S.4
Bitter, W.5
Snaar-Jagalska, B.E.6
Spaink, H.P.7
-
38
-
-
79955667485
-
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
-
Meissner C, Lorenz H, Weihofen A, Selkoe DJ, Lemberg MK (2011). The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking. J Neurochem 117, 856-867.
-
(2011)
J Neurochem
, vol.117
, pp. 856-867
-
-
Meissner, C.1
Lorenz, H.2
Weihofen, A.3
Selkoe, D.J.4
Lemberg, M.K.5
-
39
-
-
0035367786
-
A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/β-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans
-
DOI 10.1006/geno.2001.6548
-
Mink M, Fogelgren B, Olszewski K, Maroy P, Csiszar K (2001). A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans. Genomics 74, 234-244. (Pubitemid 32550145)
-
(2001)
Genomics
, vol.74
, Issue.2
, pp. 234-244
-
-
Mink, M.1
Fogelgren, B.2
Olszewski, K.3
Maroy, P.4
Csiszar, K.5
-
40
-
-
33846471122
-
Proteasome-independent functions of ubiquitin in endocytosis and signaling
-
DOI 10.1126/science.1127085
-
Mukhopadhyay D, Riezman H (2007). Proteasome-independent functions of ubiquitin in endocytosis and signaling. Science 315, 201-205. (Pubitemid 46166358)
-
(2007)
Science
, vol.315
, Issue.5809
, pp. 201-205
-
-
Mukhopadhyay, D.1
Riezman, H.2
-
41
-
-
33745068109
-
Altered cleavage and localization of PINK1 to aggresomes in thepresence of proteasomal stress
-
DOI 10.1111/j.1471-4159.2006.03845.x
-
Muqit MM et al. (2006). Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress. J Neurochem 98, 156-169. (Pubitemid 43882941)
-
(2006)
Journal of Neurochemistry
, vol.98
, Issue.1
, pp. 156-169
-
-
Muqit, M.M.K.1
Abou-Sleiman, P.M.2
Saurin, A.T.3
Harvey, K.4
Gandhi, S.5
Deas, E.6
Eaton, S.7
Payne Smith, M.D.8
Venner, K.9
Matilla, A.10
Healy, D.G.11
Gilks, W.P.12
Lees, A.J.13
Holton, J.14
Revesz, T.15
Parker, P.J.16
Harvey, R.J.17
Wood, N.W.18
Latchman, D.S.19
-
42
-
-
79953185407
-
A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1: Activation of AKT via mTORC2
-
Murata H, Sakaguchi M, Jin Y, Sakaguchi Y, Futami J, Yamada H, Kataoka K, Huh NH (2011a). A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1: activation of AKT via mTORC2. J Biol Chem 286, 7182-7189.
-
(2011)
J Biol Chem
, vol.286
, pp. 7182-7189
-
-
Murata, H.1
Sakaguchi, M.2
Jin, Y.3
Sakaguchi, Y.4
Futami, J.5
Yamada, H.6
Kataoka K.Huh, N.H.7
-
43
-
-
79956035625
-
Multiple functions of PINK1 at different intracellular locations: Beyond neurodegenerative diseases
-
Murata H, Sakaguchi M, Kataoka K, Huh NH (2011b). Multiple functions of PINK1 at different intracellular locations: beyond neurodegenerative diseases. Cell Cycle 10, 1518-1519.
-
(2011)
Cell Cycle
, vol.10
, pp. 1518-1519
-
-
Murata, H.1
Sakaguchi, M.2
Kataoka, K.3
Huh, N.H.4
-
44
-
-
0242321145
-
BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential
-
DOI 10.1016/S0304-3835(03)00443-9
-
Nakajima A, Kataoka K, Hong M, Sakaguchi M, Huh NH (2003). BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential. Cancer Lett 201, 195-201. (Pubitemid 37357169)
-
(2003)
Cancer Letters
, vol.201
, Issue.2
, pp. 195-201
-
-
Nakajima, A.1
Kataoka, K.2
Hong, M.3
Sakaguchi, M.4
Huh, N.-H.5
-
45
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra D, Tanaka A, Suen DF, Youle RJ (2008). Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 183, 795-803.
-
(2008)
J Cell Biol
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
46
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
Narendra DP, Jin SM, Tanaka A, Suen DF, Gautier CA, Shen J, Cookson MR, Youle RJ (2010). PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol 8, e1000298.
-
(2010)
PLoS Biol
, vol.8
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
Cookson, M.R.7
Youle, R.J.8
-
47
-
-
34247566510
-
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
-
DOI 10.1038/nri2079, PII NRI2079
-
O'Neill LA, Bowie AG (2007). The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat Rev Immunol 7, 353-364. (Pubitemid 46674493)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.5
, pp. 353-364
-
-
O'Neill, L.A.J.1
Bowie, A.G.2
-
48
-
-
84866072587
-
PINK1 autophosphorylation upon membrane potential dissipation is essential for parkin recruitment to damaged mitochondria
-
Okatsu K et al. (2012). PINK1 autophosphorylation upon membrane potential dissipation is essential for parkin recruitment to damaged mitochondria. Nat Commun 3, 1016.
-
(2012)
Nat Commun
, vol.3
, pp. 1016
-
-
Okatsu, K.1
-
49
-
-
84864332905
-
DSarm/Sarm1 is required for activation of an injury-induced axon death pathway
-
Osterloh JM et al. (2012). dSarm/Sarm1 is required for activation of an injury-induced axon death pathway. Science 337, 481-484.
-
(2012)
Science
, vol.337
, pp. 481-484
-
-
Osterloh, J.M.1
-
50
-
-
84863178511
-
Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: Definition of the critical region and residues in the signal sequence
-
Panneerselvam P, Singh LP, Ho B, Chen J, Ding JL (2012). Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: definition of the critical region and residues in the signal sequence. Biochem J 442, 263-271.
-
(2012)
Biochem J
, vol.442
, pp. 263-271
-
-
Panneerselvam, P.1
Singh, L.P.2
Ho, B.3
Chen, J.4
Ding, J.L.5
-
51
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
DOI 10.1038/nature04788, PII N04788
-
Park J, Lee SB, Lee S, Kim Y, Song S, Kim S, Bae E, Kim J, Shong M, Kim JM, Chung J (2006). Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 441, 1157-1161. (Pubitemid 43990737)
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
Kim, Y.4
Song, S.5
Kim, S.6
Bae, E.7
Kim, J.8
Shong, M.9
Kim, J.-M.10
Chung, J.11
-
52
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
DOI 10.1126/science.276.5321.2045
-
Polymeropoulos MH et al. (1997). Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276, 2045-2047. (Pubitemid 27443610)
-
(1997)
Science
, vol.276
, Issue.5321
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
53
-
-
77955844260
-
The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway
-
Poole AC, Thomas RE, Yu S, Vincow ES, Pallanck L (2010). The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway. PLoS One 5, e10054.
-
(2010)
PLoS One
, vol.5
-
-
Poole, A.C.1
Thomas, R.E.2
Yu, S.3
Vincow, E.S.4
Pallanck, L.5
-
54
-
-
79952369437
-
Mutations in PINK1 and parkin impair ubiquitination of mitofusins in human fibroblasts
-
Rakovic A, Grunewald A, Kottwitz J, Bruggemann N, Pramstaller PP, Lohmann K, Klein C (2011). Mutations in PINK1 and parkin impair ubiquitination of mitofusins in human fibroblasts. PLoS One 6, e16746.
-
(2011)
PLoS One
, vol.6
-
-
Rakovic, A.1
Grunewald, A.2
Kottwitz, J.3
Bruggemann, N.4
Pramstaller, P.P.5
Lohmann, K.6
Klein, C.7
-
55
-
-
27944444154
-
Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism
-
DOI 10.1093/hmg/ddi377
-
Silvestri L, Caputo V, Bellacchio E, Atorino L, Dallapiccola B, Valente EM, Casari G (2005). Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism. Hum Mol Genet 14, 3477-3492. (Pubitemid 41672130)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.22
, pp. 3477-3492
-
-
Silvestri, L.1
Caputo, V.2
Bellacchio, E.3
Atorino, L.4
Dallapiccola, B.5
Valente, E.M.6
Casari, G.7
-
56
-
-
25444498785
-
Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease
-
DOI 10.1093/hmg/ddi215
-
Strauss KM et al. (2005). Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease. Hum Mol Genet 14, 2099-2111. (Pubitemid 41418010)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.15
, pp. 2099-2111
-
-
Strauss, K.M.1
Martins, L.M.2
Plun-Favreau, H.3
Marx, F.P.4
Kautzmann, S.5
Berg, D.6
Gasser, T.7
Wszolek, Z.8
Muller, T.9
Bornemann, A.10
Wolburg, H.11
Downward, J.12
Riess, O.13
Schulz, J.B.14
Kruger, R.15
-
57
-
-
78650729600
-
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by parkin
-
Tanaka A, Cleland MM, Xu S, Narendra DP, Suen DF, Karbowski M, Youle RJ (2010). Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by parkin. J Cell Biol 191, 1367-1380.
-
(2010)
J Cell Biol
, vol.191
, pp. 1367-1380
-
-
Tanaka, A.1
Cleland, M.M.2
Xu, S.3
Narendra, D.P.4
Suen, D.F.5
Karbowski, M.6
Youle, R.J.7
-
58
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
DOI 10.1126/science.1096284
-
Valente EM et al. (2004). Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304, 1158-1160. (Pubitemid 38661852)
-
(2004)
Science
, vol.304
, Issue.5674
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.K.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
Albanese, A.11
Nussbaum, R.12
Gonzalez-Maldonado, R.13
Deller, T.14
Salvi, S.15
Cortelli, P.16
Gilks, W.P.17
Latchman, D.S.18
Harvey, R.J.19
Dallapiccola, B.20
Auburger, G.21
Wood, N.W.22
more..
-
59
-
-
75949098487
-
PINK1-dependent recruitment of parkin to mitochondria in mitophagy
-
Vives-Bauza C et al. (2010). PINK1-dependent recruitment of parkin to mitochondria in mitophagy. Proc Natl Acad Sci USA 107, 378-383.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 378-383
-
-
Vives-Bauza, C.1
-
60
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
DOI 10.1038/35085597
-
Wang C, Deng L, Hong M, Akkaraju GR, Inoue J, Chen ZJ (2001). TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 412, 346-351. (Pubitemid 32694385)
-
(2001)
Nature
, vol.412
, Issue.6844
, pp. 346-351
-
-
Wang, C.1
Deng, L.2
Hong, M.3
Akkaraju, G.R.4
Inoue, J.-I.5
Chen, Z.J.6
-
61
-
-
0242720415
-
TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology
-
DOI 10.1002/bies.10352
-
Wu H, Arron JR (2003). TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology. Bioessays 25, 1096-1105. (Pubitemid 37411769)
-
(2003)
BioEssays
, vol.25
, Issue.11
, pp. 1096-1105
-
-
Wu, H.1
Arron, J.R.2
-
62
-
-
0033197872
-
The structural basis for the recognition of diverse receptor sequences by TRAF2
-
DOI 10.1016/S1097-2765(00)80334-2
-
Ye H, Park YC, Kreishman M, Kieff E, Wu H (1999). The structural basis for the recognition of diverse receptor sequences by TRAF2. Mol Cell 4, 321-330. (Pubitemid 29499785)
-
(1999)
Molecular Cell
, vol.4
, Issue.3
, pp. 321-330
-
-
Ye, H.1
Park, Y.C.2
Kreishman, M.3
Kieff, E.4
Wu, H.5
-
63
-
-
79957472437
-
Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane
-
Yoshii SR, Kishi C, Ishihara N, Mizushima N (2011). Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane. J Biol Chem 286, 19630-19640.
-
(2011)
J Biol Chem
, vol.286
, pp. 19630-19640
-
-
Yoshii, S.R.1
Kishi, C.2
Ishihara, N.3
Mizushima, N.4
-
64
-
-
8844233579
-
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
-
DOI 10.1016/j.neuron.2004.11.005, PII S0896627304007202
-
Zimprich A et al. (2004). Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 44, 601-607. (Pubitemid 39531225)
-
(2004)
Neuron
, vol.44
, Issue.4
, pp. 601-607
-
-
Zimprich, A.1
Biskup, S.2
Leitner, P.3
Lichtner, P.4
Farrer, M.5
Lincoln, S.6
Kachergus, J.7
Hulihan, M.8
Uitti, R.J.9
Calne, D.B.10
Stoessl, A.J.11
Pfeiffer, R.F.12
Patenge, N.13
Carbajal, I.C.14
Vieregge, P.15
Asmus, F.16
Muller-Myhsok, B.17
Dickson, D.W.18
Meitinger, T.19
Strom, T.M.20
Wszolek, Z.K.21
Gasser, T.22
more..
-
65
-
-
77950384477
-
Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
-
Ziviani E, Tao RN, Whitworth AJ (2010). Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin. Proc Natl Acad Sci USA107, 5018-5023. Technology
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5018-5023
-
-
Ziviani, E.1
Tao, R.N.2
Whitworth, A.J.3
|