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Volumn 24, Issue 18, 2013, Pages 2772-2784

SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; PARKIN; STERILE ALPHA AND TIR MOTIF CONTAINING 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

EID: 84884494185     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E13-01-0016     Document Type: Article
Times cited : (60)

References (65)
  • 1
    • 33750459730 scopus 로고    scopus 로고
    • Parkinsonism genes: Culprits and clues
    • DOI 10.1111/j.1471-4159.2006.04102.x
    • Abeliovich A, Flint Beal M (2006). Parkinsonism genes: culprits and clues. J Neurochem 99, 1062-1072. (Pubitemid 44655273)
    • (2006) Journal of Neurochemistry , vol.99 , Issue.4 , pp. 1062-1072
    • Abeliovich, A.1    Flint Beal, M.2
  • 3
    • 38949205955 scopus 로고    scopus 로고
    • SARM: A novel Toll-like receptor adaptor, is functionally conserved from arthropod to human
    • DOI 10.1016/j.molimm.2007.09.030, PII S016158900700781X
    • Belinda LW, Wei WX, Hanh BT, Lei LX, Bow H, Ling DJ (2008). SARM: a novel Toll-like receptor adaptor, is functionally conserved from arthropod to human. Mol Immunol 45, 1732-1742. (Pubitemid 351221135)
    • (2008) Molecular Immunology , vol.45 , Issue.6 , pp. 1732-1742
    • Belinda, L.W.-C.1    Wei, W.X.2    Hanh, B.T.H.3    Lei, L.X.4    Bow, H.5    Ling, D.J.6
  • 6
    • 0029761275 scopus 로고    scopus 로고
    • TRAF6 is a signal transducer for interleukin-1
    • DOI 10.1038/383443a0
    • Cao Z, Xiong J, Takeuchi M, Kurama T, Goeddel DV (1996). TRAF6 is a signal transducer for interleukin-1. Nature 383, 443-446. (Pubitemid 26330834)
    • (1996) Nature , vol.383 , Issue.6599 , pp. 443-446
    • Cao, Z.1    Xiong, J.2    Takeuchi, M.3    Kurama, T.4    Goeddel, D.V.5
  • 8
    • 79960817201 scopus 로고    scopus 로고
    • Microtubule-based localization of a synaptic calcium-signaling complex is required for left-right neuronal asymmetry in C. Elegans
    • Chang C, Hsieh YW, Lesch BJ, Bargmann CI, Chuang CF (2011). Microtubule-based localization of a synaptic calcium-signaling complex is required for left-right neuronal asymmetry in C. elegans. Development 138, 3509-3518.
    • (2011) Development , vol.138 , pp. 3509-3518
    • Chang, C.1    Hsieh, Y.W.2    Lesch, B.J.3    Bargmann, C.I.4    Chuang, C.F.5
  • 9
    • 79958191516 scopus 로고    scopus 로고
    • Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology
    • Chen CY, Lin CW, Chang CY, Jiang ST, Hsueh YP (2011). Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology. J Cell Biol 193, 769-784.
    • (2011) J Cell Biol , vol.193 , pp. 769-784
    • Chen, C.Y.1    Lin, C.W.2    Chang, C.Y.3    Jiang, S.T.4    Hsueh, Y.P.5
  • 10
    • 12144283454 scopus 로고    scopus 로고
    • A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling
    • DOI 10.1101/gad.1276505
    • Chuang CF, Bargmann CI (2005). A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling. Genes Dev 19, 270-281. (Pubitemid 40111122)
    • (2005) Genes and Development , vol.19 , Issue.2 , pp. 270-281
    • Chuang, C.-F.1    Bargmann, C.I.2
  • 11
    • 33745589773 scopus 로고    scopus 로고
    • Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
    • DOI 10.1038/nature04779, PII N04779
    • Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, Seol JH, Yoo SJ, Hay BA, Guo M (2006). Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 441, 1162-1166. (Pubitemid 43990738)
    • (2006) Nature , vol.441 , Issue.7097 , pp. 1162-1166
    • Clark, I.E.1    Dodson, M.W.2    Jiang, C.3    Cao, J.H.4    Huh, J.R.5    Seol, J.H.6    Yoo, S.J.7    Hay, B.A.8    Guo, M.9
  • 13
    • 38449116840 scopus 로고    scopus 로고
    • Studies of SARM1 uncover similarities between immune and neuronal responses to danger
    • Dalod M (2007). Studies of SARM1 uncover similarities between immune and neuronal responses to danger. Sci STKE 2007, pe73.
    • (2007) Sci STKE , vol.2007
    • Dalod, M.1
  • 14
    • 79551574736 scopus 로고    scopus 로고
    • PINK1 cleavage at position A103 by the mitochondrial protease PARL
    • Deas E et al. (2011). PINK1 cleavage at position A103 by the mitochondrial protease PARL. Hum Mol Genet 20, 867-879.
    • (2011) Hum Mol Genet , vol.20 , pp. 867-879
    • Deas, E.1
  • 15
    • 27144469287 scopus 로고    scopus 로고
    • Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y
    • DOI 10.1016/j.bbrc.2005.09.178, PII S0006291X05022205
    • Deng H, Jankovic J, Guo Y, Xie W, Le W (2005). Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y. Biochem Biophys Res Commun 337, 1133-1138. (Pubitemid 41505244)
    • (2005) Biochemical and Biophysical Research Communications , vol.337 , Issue.4 , pp. 1133-1138
    • Deng, H.1    Jankovic, J.2    Guo, Y.3    Xie, W.4    Le, W.5
  • 17
    • 78649463381 scopus 로고    scopus 로고
    • Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
    • Gegg ME, Cooper JM, Chau KY, Rojo M, Schapira AH, Taanman JW (2010). Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy. Hum Mol Genet 19, 4861-4870.
    • (2010) Hum Mol Genet , vol.19 , pp. 4861-4870
    • Gegg, M.E.1    Cooper, J.M.2    Chau, K.Y.3    Rojo, M.4    Schapira, A.H.5    Taanman, J.W.6
  • 19
    • 79960493052 scopus 로고    scopus 로고
    • Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1
    • Glauser L, Sonnay S, Stafa K, Moore DJ (2011). Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1. J Neurochem 118, 636-645.
    • (2011) J Neurochem , vol.118 , pp. 636-645
    • Glauser, L.1    Sonnay, S.2    Stafa, K.3    Moore, D.J.4
  • 23
    • 4344681293 scopus 로고    scopus 로고
    • Pathogenetic mechanisms of parkin in Parkinson's disease
    • DOI 10.1016/S0140-6736(04)16901-8, PII S0140673604169018
    • Hattori N, Mizuno Y (2004). Pathogenetic mechanisms of parkin in Parkinson's disease. Lancet 364, 722-724. (Pubitemid 39140630)
    • (2004) Lancet , vol.364 , Issue.9435 , pp. 722-724
    • Hattori, N.1    Mizuno, P.Y.2
  • 24
    • 0033525582 scopus 로고    scopus 로고
    • Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair
    • Hofmann RM, Pickart CM (1999). Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair. Cell 96, 645-653. (Pubitemid 29122807)
    • (1999) Cell , vol.96 , Issue.5 , pp. 645-653
    • Hofmann, R.M.1    Pickart, C.M.2
  • 25
    • 0030032106 scopus 로고    scopus 로고
    • TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
    • DOI 10.1016/S0092-8674(00)80984-8
    • Hsu H, Shu HB, Pan MG, Goeddel DV (1996). TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 84, 299-308. (Pubitemid 26042835)
    • (1996) Cell , vol.84 , Issue.2 , pp. 299-308
    • Hsu, H.1    Shu, H.-B.2    Pan, M.-G.3    Goeddel, D.V.4
  • 26
    • 78649685455 scopus 로고    scopus 로고
    • Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
    • Jin SM, Lazarou M, Wang C, Kane LA, Narendra DP, Youle RJ (2010). Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL. J Cell Biol 191, 933-942.
    • (2010) J Cell Biol , vol.191 , pp. 933-942
    • Jin, S.M.1    Lazarou, M.2    Wang, C.3    Kane, L.A.4    Narendra, D.P.5    Youle, R.J.6
  • 30
    • 84864267876 scopus 로고    scopus 로고
    • PINK1 is activated by mitochondrial membrane potential depolarization and stimulates parkin E3 ligase activity by phosphorylating serine 65
    • Kondapalli C et al. (2012). PINK1 is activated by mitochondrial membrane potential depolarization and stimulates parkin E3 ligase activity by phosphorylating serine 65. Open Biol 2, 120080.
    • (2012) Open Biol , vol.2 , pp. 120080
    • Kondapalli, C.1
  • 31
    • 33947506493 scopus 로고    scopus 로고
    • Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of IκB kinase activation
    • DOI 10.1074/jbc.M609503200
    • Lamothe B, Besse A, Campos AD, Webster WK, Wu H, Darnay BG (2007). Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation. J Biol Chem 282, 4102-4112. (Pubitemid 47084488)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.6 , pp. 4102-4112
    • Lamothe, B.1    Besse, A.2    Campos, A.D.3    Webster, W.K.4    Wu, H.5    Darnay, B.G.6
  • 32
    • 84857032953 scopus 로고    scopus 로고
    • Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase parkin
    • Lazarou M, Jin SM, Kane LA, Youle RJ (2012). Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase parkin. Dev Cell 22, 320-333.
    • (2012) Dev Cell , vol.22 , pp. 320-333
    • Lazarou, M.1    Jin, S.M.2    Kane, L.A.3    Youle, R.J.4
  • 33
    • 84866348798 scopus 로고    scopus 로고
    • PINK1 stimulates interleukin-1beta-mediated inflammatory signaling via the positive regulation of TRAF6 and TAK1
    • Lee HJ, Jang SH, Kim H, Yoon JH, Chung KC (2012). PINK1 stimulates interleukin-1beta-mediated inflammatory signaling via the positive regulation of TRAF6 and TAK1. Cell Mol Life Sci 69, 3301-3315.
    • (2012) Cell Mol Life Sci , vol.69 , pp. 3301-3315
    • Lee, H.J.1    Jang, S.H.2    Kim, H.3    Yoon, J.H.4    Chung, K.C.5
  • 35
    • 4444258208 scopus 로고    scopus 로고
    • Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-κB activation by Toll-like receptor (TLR)-2 and TLR4
    • DOI 10.1074/jbc.C400289200
    • Mansell A, Brint E, Gould JA, O'Neill LA, Hertzog PJ (2004). Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kappaB activation by toll-like receptor (TLR)-2 and TLR4. J Biol Chem 279, 37227-37230. (Pubitemid 39195427)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.36 , pp. 37227-37230
    • Mansell, A.1    Brint, E.2    Gould, J.A.3    O'Neill, L.A.4    Hertzog, P.J.5
  • 36
    • 77951181836 scopus 로고    scopus 로고
    • PINK1 stabilized by mitochondrial depolarization recruits parkin to damaged mitochondria and activates latent parkin for mitophagy
    • Matsuda N et al. (2010). PINK1 stabilized by mitochondrial depolarization recruits parkin to damaged mitochondria and activates latent parkin for mitophagy. J Cell Biol 189, 211-221.
    • (2010) J Cell Biol , vol.189 , pp. 211-221
    • Matsuda, N.1
  • 38
    • 79955667485 scopus 로고    scopus 로고
    • The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
    • Meissner C, Lorenz H, Weihofen A, Selkoe DJ, Lemberg MK (2011). The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking. J Neurochem 117, 856-867.
    • (2011) J Neurochem , vol.117 , pp. 856-867
    • Meissner, C.1    Lorenz, H.2    Weihofen, A.3    Selkoe, D.J.4    Lemberg, M.K.5
  • 39
    • 0035367786 scopus 로고    scopus 로고
    • A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/β-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans
    • DOI 10.1006/geno.2001.6548
    • Mink M, Fogelgren B, Olszewski K, Maroy P, Csiszar K (2001). A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans. Genomics 74, 234-244. (Pubitemid 32550145)
    • (2001) Genomics , vol.74 , Issue.2 , pp. 234-244
    • Mink, M.1    Fogelgren, B.2    Olszewski, K.3    Maroy, P.4    Csiszar, K.5
  • 40
    • 33846471122 scopus 로고    scopus 로고
    • Proteasome-independent functions of ubiquitin in endocytosis and signaling
    • DOI 10.1126/science.1127085
    • Mukhopadhyay D, Riezman H (2007). Proteasome-independent functions of ubiquitin in endocytosis and signaling. Science 315, 201-205. (Pubitemid 46166358)
    • (2007) Science , vol.315 , Issue.5809 , pp. 201-205
    • Mukhopadhyay, D.1    Riezman, H.2
  • 42
    • 79953185407 scopus 로고    scopus 로고
    • A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1: Activation of AKT via mTORC2
    • Murata H, Sakaguchi M, Jin Y, Sakaguchi Y, Futami J, Yamada H, Kataoka K, Huh NH (2011a). A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1: activation of AKT via mTORC2. J Biol Chem 286, 7182-7189.
    • (2011) J Biol Chem , vol.286 , pp. 7182-7189
    • Murata, H.1    Sakaguchi, M.2    Jin, Y.3    Sakaguchi, Y.4    Futami, J.5    Yamada, H.6    Kataoka K.Huh, N.H.7
  • 43
    • 79956035625 scopus 로고    scopus 로고
    • Multiple functions of PINK1 at different intracellular locations: Beyond neurodegenerative diseases
    • Murata H, Sakaguchi M, Kataoka K, Huh NH (2011b). Multiple functions of PINK1 at different intracellular locations: beyond neurodegenerative diseases. Cell Cycle 10, 1518-1519.
    • (2011) Cell Cycle , vol.10 , pp. 1518-1519
    • Murata, H.1    Sakaguchi, M.2    Kataoka, K.3    Huh, N.H.4
  • 44
    • 0242321145 scopus 로고    scopus 로고
    • BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential
    • DOI 10.1016/S0304-3835(03)00443-9
    • Nakajima A, Kataoka K, Hong M, Sakaguchi M, Huh NH (2003). BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential. Cancer Lett 201, 195-201. (Pubitemid 37357169)
    • (2003) Cancer Letters , vol.201 , Issue.2 , pp. 195-201
    • Nakajima, A.1    Kataoka, K.2    Hong, M.3    Sakaguchi, M.4    Huh, N.-H.5
  • 45
    • 58149314211 scopus 로고    scopus 로고
    • Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
    • Narendra D, Tanaka A, Suen DF, Youle RJ (2008). Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 183, 795-803.
    • (2008) J Cell Biol , vol.183 , pp. 795-803
    • Narendra, D.1    Tanaka, A.2    Suen, D.F.3    Youle, R.J.4
  • 47
    • 34247566510 scopus 로고    scopus 로고
    • The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
    • DOI 10.1038/nri2079, PII NRI2079
    • O'Neill LA, Bowie AG (2007). The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat Rev Immunol 7, 353-364. (Pubitemid 46674493)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.5 , pp. 353-364
    • O'Neill, L.A.J.1    Bowie, A.G.2
  • 48
    • 84866072587 scopus 로고    scopus 로고
    • PINK1 autophosphorylation upon membrane potential dissipation is essential for parkin recruitment to damaged mitochondria
    • Okatsu K et al. (2012). PINK1 autophosphorylation upon membrane potential dissipation is essential for parkin recruitment to damaged mitochondria. Nat Commun 3, 1016.
    • (2012) Nat Commun , vol.3 , pp. 1016
    • Okatsu, K.1
  • 49
    • 84864332905 scopus 로고    scopus 로고
    • DSarm/Sarm1 is required for activation of an injury-induced axon death pathway
    • Osterloh JM et al. (2012). dSarm/Sarm1 is required for activation of an injury-induced axon death pathway. Science 337, 481-484.
    • (2012) Science , vol.337 , pp. 481-484
    • Osterloh, J.M.1
  • 50
    • 84863178511 scopus 로고    scopus 로고
    • Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: Definition of the critical region and residues in the signal sequence
    • Panneerselvam P, Singh LP, Ho B, Chen J, Ding JL (2012). Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: definition of the critical region and residues in the signal sequence. Biochem J 442, 263-271.
    • (2012) Biochem J , vol.442 , pp. 263-271
    • Panneerselvam, P.1    Singh, L.P.2    Ho, B.3    Chen, J.4    Ding, J.L.5
  • 51
    • 33745602748 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
    • DOI 10.1038/nature04788, PII N04788
    • Park J, Lee SB, Lee S, Kim Y, Song S, Kim S, Bae E, Kim J, Shong M, Kim JM, Chung J (2006). Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 441, 1157-1161. (Pubitemid 43990737)
    • (2006) Nature , vol.441 , Issue.7097 , pp. 1157-1161
    • Park, J.1    Lee, S.B.2    Lee, S.3    Kim, Y.4    Song, S.5    Kim, S.6    Bae, E.7    Kim, J.8    Shong, M.9    Kim, J.-M.10    Chung, J.11
  • 53
    • 77955844260 scopus 로고    scopus 로고
    • The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway
    • Poole AC, Thomas RE, Yu S, Vincow ES, Pallanck L (2010). The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway. PLoS One 5, e10054.
    • (2010) PLoS One , vol.5
    • Poole, A.C.1    Thomas, R.E.2    Yu, S.3    Vincow, E.S.4    Pallanck, L.5
  • 59
    • 75949098487 scopus 로고    scopus 로고
    • PINK1-dependent recruitment of parkin to mitochondria in mitophagy
    • Vives-Bauza C et al. (2010). PINK1-dependent recruitment of parkin to mitochondria in mitophagy. Proc Natl Acad Sci USA 107, 378-383.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 378-383
    • Vives-Bauza, C.1
  • 60
    • 0035913278 scopus 로고    scopus 로고
    • TAK1 is a ubiquitin-dependent kinase of MKK and IKK
    • DOI 10.1038/35085597
    • Wang C, Deng L, Hong M, Akkaraju GR, Inoue J, Chen ZJ (2001). TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 412, 346-351. (Pubitemid 32694385)
    • (2001) Nature , vol.412 , Issue.6844 , pp. 346-351
    • Wang, C.1    Deng, L.2    Hong, M.3    Akkaraju, G.R.4    Inoue, J.-I.5    Chen, Z.J.6
  • 61
    • 0242720415 scopus 로고    scopus 로고
    • TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology
    • DOI 10.1002/bies.10352
    • Wu H, Arron JR (2003). TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology. Bioessays 25, 1096-1105. (Pubitemid 37411769)
    • (2003) BioEssays , vol.25 , Issue.11 , pp. 1096-1105
    • Wu, H.1    Arron, J.R.2
  • 62
    • 0033197872 scopus 로고    scopus 로고
    • The structural basis for the recognition of diverse receptor sequences by TRAF2
    • DOI 10.1016/S1097-2765(00)80334-2
    • Ye H, Park YC, Kreishman M, Kieff E, Wu H (1999). The structural basis for the recognition of diverse receptor sequences by TRAF2. Mol Cell 4, 321-330. (Pubitemid 29499785)
    • (1999) Molecular Cell , vol.4 , Issue.3 , pp. 321-330
    • Ye, H.1    Park, Y.C.2    Kreishman, M.3    Kieff, E.4    Wu, H.5
  • 63
    • 79957472437 scopus 로고    scopus 로고
    • Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane
    • Yoshii SR, Kishi C, Ishihara N, Mizushima N (2011). Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane. J Biol Chem 286, 19630-19640.
    • (2011) J Biol Chem , vol.286 , pp. 19630-19640
    • Yoshii, S.R.1    Kishi, C.2    Ishihara, N.3    Mizushima, N.4
  • 65
    • 77950384477 scopus 로고    scopus 로고
    • Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
    • Ziviani E, Tao RN, Whitworth AJ (2010). Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin. Proc Natl Acad Sci USA107, 5018-5023. Technology
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 5018-5023
    • Ziviani, E.1    Tao, R.N.2    Whitworth, A.J.3


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