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Volumn 121, Issue , 2014, Pages 1-65

Glial progenitors as targets for transformation in Glioma

Author keywords

Brain; Cancer; Glioblastoma; Glioma; Neural stem cell; Oligodendrocyte progenitor cell

Indexed keywords

EPIDERMAL GROWTH FACTOR; H3F3A PROTEIN; HISTONE H3; HYPOXIA INDUCIBLE FACTOR 1ALPHA; ISOCITRATE DEHYDROGENASE; MAMMALIAN TARGET OF RAPAMYCIN; NOTCH RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; POLYCOMB GROUP PROTEIN; PROTEIN TYROSINE KINASE; SCATTER FACTOR RECEPTOR; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG; WNT1 PROTEIN;

EID: 84901505595     PISSN: 0065230X     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-800249-0.00001-9     Document Type: Chapter
Times cited : (35)

References (333)
  • 1
    • 66349110614 scopus 로고    scopus 로고
    • GFAP-Cre-mediated activation of oncogenic K-ras results in expansion of the subventricular zone and infiltrating glioma
    • Retrieved from
    • Abel T.W., Clark C., Bierie B., Chytil A., Aakre M., Gorska A., et al. GFAP-Cre-mediated activation of oncogenic K-ras results in expansion of the subventricular zone and infiltrating glioma. Molecular Cancer Research 2009, 7:645-653. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/19435821.
    • (2009) Molecular Cancer Research , vol.7 , pp. 645-653
    • Abel, T.W.1    Clark, C.2    Bierie, B.3    Chytil, A.4    Aakre, M.5    Gorska, A.6
  • 3
    • 27644543354 scopus 로고    scopus 로고
    • Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis
    • Abounader R., Laterra J. Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis. Neuro-Oncology 2005, 7(4):436-451. 10.1215/S1152851705000050.
    • (2005) Neuro-Oncology , vol.7 , Issue.4 , pp. 436-451
    • Abounader, R.1    Laterra, J.2
  • 5
    • 78149479091 scopus 로고    scopus 로고
    • MTOR signaling in glioblastoma: Lessons learned from bench to bedside
    • Akhavan D., Cloughesy T.F., Mischel P.S. mTOR signaling in glioblastoma: Lessons learned from bench to bedside. Neuro-Oncology 2010, 12(8):882-889. 10.1093/neuonc/noq052.
    • (2010) Neuro-Oncology , vol.12 , Issue.8 , pp. 882-889
    • Akhavan, D.1    Cloughesy, T.F.2    Mischel, P.S.3
  • 6
    • 84877593565 scopus 로고    scopus 로고
    • De-repression of PDGFRβ transcription promotes acquired resistance to EGFR tyrosine kinase inhibitors in glioblastoma patients
    • Akhavan D., Pourzia A.L., Nourian A.A., Williams K.J., Nathanson D., Babic I., et al. De-repression of PDGFRβ transcription promotes acquired resistance to EGFR tyrosine kinase inhibitors in glioblastoma patients. Cancer Discovery 2013, 3(5):534-547. 10.1158/2159-8290.CD-12-0502.
    • (2013) Cancer Discovery , vol.3 , Issue.5 , pp. 534-547
    • Akhavan, D.1    Pourzia, A.L.2    Nourian, A.A.3    Williams, K.J.4    Nathanson, D.5    Babic, I.6
  • 7
    • 57849109837 scopus 로고    scopus 로고
    • Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model
    • Retrieved from
    • Alcantara Llaguno S., Chen J., Kwon C.-H., Jackson E.L., Li Y., Burns D.K., et al. Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell 2009, 15:45-56. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/19111880.
    • (2009) Cancer Cell , vol.15 , pp. 45-56
    • Alcantara Llaguno, S.1    Chen, J.2    Kwon, C.-H.3    Jackson, E.L.4    Li, Y.5    Burns, D.K.6
  • 8
    • 78649986150 scopus 로고    scopus 로고
    • TGF-β receptor inhibitors target the CD44(high)/Id1(high) glioma-initiating cell population in human glioblastoma
    • Anido J., Sáez-Borderías A., Gonzàlez-Juncà A., Rodón L., Folch G., Carmona M.A., et al. TGF-β receptor inhibitors target the CD44(high)/Id1(high) glioma-initiating cell population in human glioblastoma. Cancer Cell 2010, 18(6):655-668. 10.1016/j.ccr.2010.10.023.
    • (2010) Cancer Cell , vol.18 , Issue.6 , pp. 655-668
    • Anido, J.1    Sáez-Borderías, A.2    Gonzàlez-Juncà, A.3    Rodón, L.4    Folch, G.5    Carmona, M.A.6
  • 10
    • 84879796057 scopus 로고    scopus 로고
    • Transcriptional differences between normal and glioma-derived glial progenitor cells identify a core set of dysregulated genes
    • Auvergne R.M., Sim F.J., Wang S., Chandler-Militello D., Burch J., Al Fanek Y., et al. Transcriptional differences between normal and glioma-derived glial progenitor cells identify a core set of dysregulated genes. Cell Reports 2013, 3:1-15. 10.1016/j.celrep.2013.04.035.
    • (2013) Cell Reports , vol.3 , pp. 1-15
    • Auvergne, R.M.1    Sim, F.J.2    Wang, S.3    Chandler-Militello, D.4    Burch, J.5    Al Fanek, Y.6
  • 11
    • 19044397160 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and Ink4a/Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
    • Retrieved from
    • Bachoo R.M., Maher E.A., Ligon K.L., Sharpless N.E., Chan S.S., You M.J., et al. Epidermal growth factor receptor and Ink4a/Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell 2002, 1:269-277. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/12086863.
    • (2002) Cancer Cell , vol.1 , pp. 269-277
    • Bachoo, R.M.1    Maher, E.A.2    Ligon, K.L.3    Sharpless, N.E.4    Chan, S.S.5    You, M.J.6
  • 13
    • 51049101689 scopus 로고    scopus 로고
    • Targeting cancer stem cells through L1CAM suppresses glioma growth
    • Retrieved from
    • Bao S., Wu Q., Li Z., Sathornsumetee S., Wang H., McLendon R.E., et al. Targeting cancer stem cells through L1CAM suppresses glioma growth. Cancer Research 2008, 68:6043-6048. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2739001&tool=pmcentrez&rendertype=abstract.
    • (2008) Cancer Research , vol.68 , pp. 6043-6048
    • Bao, S.1    Wu, Q.2    Li, Z.3    Sathornsumetee, S.4    Wang, H.5    McLendon, R.E.6
  • 14
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • Retrieved from
    • Bao S., Wu Q., McLendon R.E., Hao Y., Shi Q., Hjelmeland A.B., et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006, 444:756-760. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/17051156.
    • (2006) Nature , vol.444 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5    Hjelmeland, A.B.6
  • 15
    • 84861760526 scopus 로고    scopus 로고
    • Kinetics of inhibitor cycling underlie therapeutic disparities between EGFR-driven lung and brain cancers
    • Barkovich K.J., Hariono S., Garske A.L., Zhang J., Blair J.A., Fan Q.-W., et al. Kinetics of inhibitor cycling underlie therapeutic disparities between EGFR-driven lung and brain cancers. Cancer Discovery 2012, 2(5):450-457. 10.1158/2159-8290.CD-11-0287.
    • (2012) Cancer Discovery , vol.2 , Issue.5 , pp. 450-457
    • Barkovich, K.J.1    Hariono, S.2    Garske, A.L.3    Zhang, J.4    Blair, J.A.5    Fan, Q.-W.6
  • 16
    • 77954720781 scopus 로고    scopus 로고
    • Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma
    • Batchelor T.T., Duda D.G., Di Tomaso E., Ancukiewicz M., Plotkin S.R., Gerstner E., et al. Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma. Journal of Clinical Oncology 2010, 28:2817-2823. 10.1200/JCO.2009.26.3988.
    • (2010) Journal of Clinical Oncology , vol.28 , pp. 2817-2823
    • Batchelor, T.T.1    Duda, D.G.2    Di Tomaso, E.3    Ancukiewicz, M.4    Plotkin, S.R.5    Gerstner, E.6
  • 17
    • 58149481284 scopus 로고    scopus 로고
    • The novel orally bioavailable inhibitor of phosphoinositol-3-kinase and mammalian target of rapamycin, NVP-BEZ235, inhibits growth and proliferation in multiple myeloma
    • Baumann P., Mandl-Weber S., Oduncu F., Schmidmaier R. The novel orally bioavailable inhibitor of phosphoinositol-3-kinase and mammalian target of rapamycin, NVP-BEZ235, inhibits growth and proliferation in multiple myeloma. Experimental Cell Research 2009, 315(3):485-497. 10.1016/j.yexcr.2008.11.007.
    • (2009) Experimental Cell Research , vol.315 , Issue.3 , pp. 485-497
    • Baumann, P.1    Mandl-Weber, S.2    Oduncu, F.3    Schmidmaier, R.4
  • 18
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • Retrieved from
    • Ben-Porath I., Thomson M.W., Carey V.J., Ge R., Bell G.W., Regev A., et al. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nature Genetics 2008, 40:499-507. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/18443585.
    • (2008) Nature Genetics , vol.40 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3    Ge, R.4    Bell, G.W.5    Regev, A.6
  • 19
    • 80052608062 scopus 로고    scopus 로고
    • Mutations in CIC and FUBP1 contribute to human oligodendroglioma
    • Bettegowda C., Agrawal N., Jiao Y., Sausen M., Wood L.D., Hruban R.H. Mutations in CIC and FUBP1 contribute to human oligodendroglioma. Science 2011, 333(6048):1453-1455.
    • (2011) Science , vol.333 , Issue.6048 , pp. 1453-1455
    • Bettegowda, C.1    Agrawal, N.2    Jiao, Y.3    Sausen, M.4    Wood, L.D.5    Hruban, R.H.6
  • 22
    • 80051597880 scopus 로고    scopus 로고
    • Enhanced efficacy of IGF1R inhibition in pediatric glioblastoma by combinatorial targeting of PDGFRα/β
    • Bielen A., Perryman L., Box G.M., Valenti M., de Haven Brandon A., Martins V., et al. Enhanced efficacy of IGF1R inhibition in pediatric glioblastoma by combinatorial targeting of PDGFRα/β. Molecular Cancer Therapeutics 2011, 10(8):1407-1418. 10.1158/1535-7163.MCT-11-0205.
    • (2011) Molecular Cancer Therapeutics , vol.10 , Issue.8 , pp. 1407-1418
    • Bielen, A.1    Perryman, L.2    Box, G.M.3    Valenti, M.4    de Haven Brandon, A.5    Martins, V.6
  • 23
    • 84877621282 scopus 로고    scopus 로고
    • Histone H3.3 mutations drive pediatric glioblastoma through upregulation of MYCN
    • Bjerke L., Mackay A., Nandhabalan M., Burford A., Jury A., Popov S., et al. Histone H3.3 mutations drive pediatric glioblastoma through upregulation of MYCN. Cancer Discovery 2013, 3:512-519.
    • (2013) Cancer Discovery , vol.3 , pp. 512-519
    • Bjerke, L.1    Mackay, A.2    Nandhabalan, M.3    Burford, A.4    Jury, A.5    Popov, S.6
  • 24
    • 58349111311 scopus 로고    scopus 로고
    • IDH1mutations at residue p.R132 (IDH1 R132) occur frequently in high-grade gliomas but not in other solid tumors
    • Bleeker F.E., Lamba S., Leenstra S., Troost D., Hulsebos T., Vandertop W.P., et al. IDH1mutations at residue p.R132 (IDH1 R132) occur frequently in high-grade gliomas but not in other solid tumors. Human Mutation 2009, 30(1):7-11.
    • (2009) Human Mutation , vol.30 , Issue.1 , pp. 7-11
    • Bleeker, F.E.1    Lamba, S.2    Leenstra, S.3    Troost, D.4    Hulsebos, T.5    Vandertop, W.P.6
  • 25
    • 84876880478 scopus 로고    scopus 로고
    • A multi-parametric imaging investigation of the response of C6 glioma xenografts to MLN0518 (tandutinib) treatment
    • Boult J.K.R., Terkelsen J., Walker-Samuel S., Bradley D.P., Robinson S.P. A multi-parametric imaging investigation of the response of C6 glioma xenografts to MLN0518 (tandutinib) treatment. PLoS One 2013, 8(4):e63024. 10.1371/journal.pone.0063024.
    • (2013) PLoS One , vol.8 , Issue.4
    • Boult, J.K.R.1    Terkelsen, J.2    Walker-Samuel, S.3    Bradley, D.P.4    Robinson, S.P.5
  • 26
    • 0036842720 scopus 로고    scopus 로고
    • CD44H is expressed by cells of the oligodendrocyte lineage and by oligodendrogliomas in humans
    • Retrieved from
    • Bouvier-Labit C., Liprandi A., Monti G., Pellissier J.F., Figarella-Branger D. CD44H is expressed by cells of the oligodendrocyte lineage and by oligodendrogliomas in humans. Journal of Neuro-Oncology 2002, 60:127-134. Retrieved from. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12635659.
    • (2002) Journal of Neuro-Oncology , vol.60 , pp. 127-134
    • Bouvier-Labit, C.1    Liprandi, A.2    Monti, G.3    Pellissier, J.F.4    Figarella-Branger, D.5
  • 28
    • 70849122697 scopus 로고    scopus 로고
    • Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations
    • C. Creighton, Ed
    • Brennan C., Momota H., Hambardzumyan D., Ozawa T., Tandon A., Pedraza A., et al. Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations. PLoS One 2009, 4(11):e7752. C. Creighton, Ed. 10.1371/journal.pone.0007752.
    • (2009) PLoS One , vol.4 , Issue.11
    • Brennan, C.1    Momota, H.2    Hambardzumyan, D.3    Ozawa, T.4    Tandon, A.5    Pedraza, A.6
  • 30
    • 33847685719 scopus 로고    scopus 로고
    • Institutional experience with chloroquine as an adjuvant to the therapy for glioblastoma multiforme
    • Briceño E., Calderon A., Sotelo J. Institutional experience with chloroquine as an adjuvant to the therapy for glioblastoma multiforme. Surgical Neurology 2007, 67(4):388-391. 10.1016/j.surneu.2006.08.080.
    • (2007) Surgical Neurology , vol.67 , Issue.4 , pp. 388-391
    • Briceño, E.1    Calderon, A.2    Sotelo, J.3
  • 32
    • 64949155000 scopus 로고    scopus 로고
    • Activity of a novel, dual PI3-kinase/mTor inhibitor NVP-BEZ235 against primary human pancreatic cancers grown as orthotopic xenografts
    • Cao P., Maira S.-M., García-Echeverría C., Hedley D.W. Activity of a novel, dual PI3-kinase/mTor inhibitor NVP-BEZ235 against primary human pancreatic cancers grown as orthotopic xenografts. British Journal of Cancer 2009, 100(8):1267-1276. 10.1038/sj.bjc.6604995.
    • (2009) British Journal of Cancer , vol.100 , Issue.8 , pp. 1267-1276
    • Cao, P.1    Maira, S.-M.2    García-Echeverría, C.3    Hedley, D.W.4
  • 33
    • 0036830642 scopus 로고    scopus 로고
    • Role of histone H3 lysine 27 methylation in Polycomb-group silencing
    • Retrieved from
    • Cao R., Wang L., Wang H., Xia L., Erdjument-Bromage H., Tempst P., et al. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 2002, 298:1039-1043. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/12351676.
    • (2002) Science , vol.298 , pp. 1039-1043
    • Cao, R.1    Wang, L.2    Wang, H.3    Xia, L.4    Erdjument-Bromage, H.5    Tempst, P.6
  • 34
    • 51349164790 scopus 로고    scopus 로고
    • Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer
    • Carracedo A., Ma L., Teruya-Feldstein J., Rojo F., Salmena L., Alimonti A., et al. Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer. The Journal of Clinical Investigation 2008, 118(9):3065-3074. 10.1172/JCI34739.
    • (2008) The Journal of Clinical Investigation , vol.118 , Issue.9 , pp. 3065-3074
    • Carracedo, A.1    Ma, L.2    Teruya-Feldstein, J.3    Rojo, F.4    Salmena, L.5    Alimonti, A.6
  • 35
    • 75149195336 scopus 로고    scopus 로고
    • The transcriptional network for mesenchymal transformation of brain tumours
    • Carro M.S., Lim W.K., Alvarez M.J., Bollo R.J., Zhao X., Snyder E.Y., et al. The transcriptional network for mesenchymal transformation of brain tumours. Nature 2009, 463(7279):318-325.
    • (2009) Nature , vol.463 , Issue.7279 , pp. 318-325
    • Carro, M.S.1    Lim, W.K.2    Alvarez, M.J.3    Bollo, R.J.4    Zhao, X.5    Snyder, E.Y.6
  • 36
    • 84877299145 scopus 로고    scopus 로고
    • The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
    • Chan K.-M., Fang D., Gan H., Hashizume R., Yu C., Schroeder M., et al. The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression. Genes & Development 2013, 27(9):985-990.
    • (2013) Genes & Development , vol.27 , Issue.9 , pp. 985-990
    • Chan, K.-M.1    Fang, D.2    Gan, H.3    Hashizume, R.4    Yu, C.5    Schroeder, M.6
  • 38
    • 84888265282 scopus 로고    scopus 로고
    • Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML
    • Chaturvedi A., Araujo Cruz M.M., Jyotsana N., Sharma A., Yun H., Görlich K., et al. Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML. Blood 2013, 122:2877-2887. 10.1182/blood-2013-03-491571.
    • (2013) Blood , vol.122 , pp. 2877-2887
    • Chaturvedi, A.1    Araujo Cruz, M.M.2    Jyotsana, N.3    Sharma, A.4    Yun, H.5    Görlich, K.6
  • 40
    • 84878248430 scopus 로고    scopus 로고
    • Modulation of the Wnt/beta-catenin pathway in human oligodendroglioma cells by Sox17 regulates proliferation and differentiation
    • Chen H.-L., Chew L.-J., Packer R.J., Gallo V. Modulation of the Wnt/beta-catenin pathway in human oligodendroglioma cells by Sox17 regulates proliferation and differentiation. Cancer Letters 2013, 335(2):361-371.
    • (2013) Cancer Letters , vol.335 , Issue.2 , pp. 361-371
    • Chen, H.-L.1    Chew, L.-J.2    Packer, R.J.3    Gallo, V.4
  • 41
    • 84865203983 scopus 로고    scopus 로고
    • A restricted cell population propagates glioblastoma growth after chemotherapy
    • Chen J., Li Y., Yu T.-S., McKay R.M., Burns D.K., Kernie S.G., et al. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature 2012, 488(7412):522-526.
    • (2012) Nature , vol.488 , Issue.7412 , pp. 522-526
    • Chen, J.1    Li, Y.2    Yu, T.-S.3    McKay, R.M.4    Burns, D.K.5    Kernie, S.G.6
  • 42
    • 57449104947 scopus 로고    scopus 로고
    • PI3K signaling in glioma-animal models and therapeutic challenges
    • Cheng C.K., Fan Q.-W., Weiss W.A. PI3K signaling in glioma-animal models and therapeutic challenges. Brain Pathology 2009, 19(1):112-120. 10.1111/j.1750-3639.2008.00233.x.
    • (2009) Brain Pathology , vol.19 , Issue.1 , pp. 112-120
    • Cheng, C.K.1    Fan, Q.-W.2    Weiss, W.A.3
  • 44
    • 77953995002 scopus 로고    scopus 로고
    • Covalent histone modifications-Miswritten, misinterpreted and mis-erased in human cancers
    • Chi P., Allis C.D., Wang G.G. Covalent histone modifications-Miswritten, misinterpreted and mis-erased in human cancers. Nature Reviews. Cancer 2010, 10(7):457-469.
    • (2010) Nature Reviews. Cancer , vol.10 , Issue.7 , pp. 457-469
    • Chi, P.1    Allis, C.D.2    Wang, G.G.3
  • 45
    • 78049241020 scopus 로고    scopus 로고
    • Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against T-cell acute lymphoblastic leukemia
    • Chiarini F., Grimaldi C., Ricci F., Tazzari P.L., Evangelisti C., Ognibene A., et al. Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against T-cell acute lymphoblastic leukemia. Cancer Research 2010, 70(20):8097-8107. 10.1158/0008-5472.CAN-10-1814.
    • (2010) Cancer Research , vol.70 , Issue.20 , pp. 8097-8107
    • Chiarini, F.1    Grimaldi, C.2    Ricci, F.3    Tazzari, P.L.4    Evangelisti, C.5    Ognibene, A.6
  • 46
    • 79952509861 scopus 로고    scopus 로고
    • Cooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain
    • Retrieved from
    • Chow L.M.L., Endersby R., Zhu X., Rankin S., Qu C., Zhang J., et al. Cooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain. Cancer Cell 2011, 19:305-316. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3060664&tool=pmcentrez&rendertype=abstract.
    • (2011) Cancer Cell , vol.19 , pp. 305-316
    • Chow, L.M.L.1    Endersby, R.2    Zhu, X.3    Rankin, S.4    Qu, C.5    Zhang, J.6
  • 47
    • 33846237601 scopus 로고    scopus 로고
    • HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity
    • Retrieved from
    • Clement V., Sanchez P., De Tribolet N., Radovanovic I., Ruiz I., Altaba A. HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity. Current Biology 2007, 17:165-172. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/17196391.
    • (2007) Current Biology , vol.17 , pp. 165-172
    • Clement, V.1    Sanchez, P.2    De Tribolet, N.3    Radovanovic, I.4    Ruiz, I.5    Altaba, A.6
  • 48
    • 33746635527 scopus 로고    scopus 로고
    • Treatment of primary glioblastoma multiforme with cetuximab, radiotherapy and temozolomide (GERT)-Phase I/II trial: Study protocol
    • Combs S.E., Heeger S., Haselmann R., Edler L., Debus J., Schulz-Ertner D. Treatment of primary glioblastoma multiforme with cetuximab, radiotherapy and temozolomide (GERT)-Phase I/II trial: Study protocol. BMC Cancer 2006, 6:133. 10.1186/1471-2407-6-133.
    • (2006) BMC Cancer , vol.6 , pp. 133
    • Combs, S.E.1    Heeger, S.2    Haselmann, R.3    Edler, L.4    Debus, J.5    Schulz-Ertner, D.6
  • 49
    • 84867658356 scopus 로고    scopus 로고
    • Histone deacetylase activity is required for human oligodendrocyte progenitor differentiation
    • Conway G.D., O'Bara M.A., Vedia B.H., Pol S.U., Sim F.J. Histone deacetylase activity is required for human oligodendrocyte progenitor differentiation. Glia 2012, 60:1944-1953. 10.1002/glia.22410.
    • (2012) Glia , vol.60 , pp. 1944-1953
    • Conway, G.D.1    O'Bara, M.A.2    Vedia, B.H.3    Pol, S.U.4    Sim, F.J.5
  • 50
    • 84860247330 scopus 로고    scopus 로고
    • The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma
    • Cooper L.A.D., Gutman D.A., Chisolm C., Appin C., Kong J., Rong Y., et al. The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma. American Journal of Pathology 2012, 180(5):2108-2119.
    • (2012) American Journal of Pathology , vol.180 , Issue.5 , pp. 2108-2119
    • Cooper, L.A.D.1    Gutman, D.A.2    Chisolm, C.3    Appin, C.4    Kong, J.5    Rong, Y.6
  • 51
    • 77958527996 scopus 로고    scopus 로고
    • The proneural molecular signature is enriched in oligodendrogliomas and predicts improved survival among diffuse gliomas
    • Cooper L.A.D., Gutman D.A., Long Q., Johnson B.A., Cholleti S.R., Kurc T., et al. The proneural molecular signature is enriched in oligodendrogliomas and predicts improved survival among diffuse gliomas. PloS One 2010, 5(9):e12548. 10.1371/journal.pone.0012548.
    • (2010) PloS One , vol.5 , Issue.9
    • Cooper, L.A.D.1    Gutman, D.A.2    Long, Q.3    Johnson, B.A.4    Cholleti, S.R.5    Kurc, T.6
  • 52
    • 84873050284 scopus 로고    scopus 로고
    • Regulatory networks defining EMT during cancer initiation and progression
    • Craene B.De, Berx G. Regulatory networks defining EMT during cancer initiation and progression. Nature Reviews Cancer 2013, 13(2):97-110.
    • (2013) Nature Reviews Cancer , vol.13 , Issue.2 , pp. 97-110
    • Craene, B.D.1    Berx, G.2
  • 54
    • 0035691884 scopus 로고    scopus 로고
    • The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis
    • Retrieved from
    • Dahmane N., Sánchez P., Gitton Y., Palma V., Sun T., Beyna M., et al. The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis. Development (Cambridge, England) 2001, 128:5201-5212. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/11748155.
    • (2001) Development (Cambridge, England) , vol.128 , pp. 5201-5212
    • Dahmane, N.1    Sánchez, P.2    Gitton, Y.3    Palma, V.4    Sun, T.5    Beyna, M.6
  • 55
    • 0035425048 scopus 로고    scopus 로고
    • PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo
    • Dai C., Celestino J.C., Okada Y., Louis D.N., Fuller G.N., Holland E.C. PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes & Development 2001, 15:1913-1925. 10.1101/gad.903001.
    • (2001) Genes & Development , vol.15 , pp. 1913-1925
    • Dai, C.1    Celestino, J.C.2    Okada, Y.3    Louis, D.N.4    Fuller, G.N.5    Holland, E.C.6
  • 56
    • 18644373850 scopus 로고    scopus 로고
    • The characteristics of astrocytomas and oligodendrogliomas are caused by two distinct and interchangeable signaling formats
    • Dai C., Lyustikman Y., Shih A., Hu X., Fuller G.N., Rosenblum M., et al. The characteristics of astrocytomas and oligodendrogliomas are caused by two distinct and interchangeable signaling formats. Neoplasia 2005, 7:397-406. 10.1593/neo.04691.
    • (2005) Neoplasia , vol.7 , pp. 397-406
    • Dai, C.1    Lyustikman, Y.2    Shih, A.3    Hu, X.4    Fuller, G.N.5    Rosenblum, M.6
  • 57
    • 0142250835 scopus 로고    scopus 로고
    • NG2-expressing glial progenitor cells: An abundant and widespread population of cycling cells in the adult rat CNS
    • Retrieved from
    • Dawson M.R.L., Polito A., Levine J.M., Reynolds R. NG2-expressing glial progenitor cells: An abundant and widespread population of cycling cells in the adult rat CNS. Molecular and Cellular Neurosciences 2003, 24:476-488. Retrieved from. http://linkinghub.elsevier.com/retrieve/pii/S1044743103002100.
    • (2003) Molecular and Cellular Neurosciences , vol.24 , pp. 476-488
    • Dawson, M.R.L.1    Polito, A.2    Levine, J.M.3    Reynolds, R.4
  • 58
    • 84865712690 scopus 로고    scopus 로고
    • The MET oncogene is a functional marker of a glioblastoma stem cell subtype
    • De Bacco F., Casanova E., Medico E., Pellegatta S., Orzan F., Albano R., et al. The MET oncogene is a functional marker of a glioblastoma stem cell subtype. Cancer Research 2012, 72(17):4537-4550.
    • (2012) Cancer Research , vol.72 , Issue.17 , pp. 4537-4550
    • De Bacco, F.1    Casanova, E.2    Medico, E.3    Pellegatta, S.4    Orzan, F.5    Albano, R.6
  • 59
    • 76749144538 scopus 로고    scopus 로고
    • A phase II study of XL184 in patients (pts) with progressive glioblastoma multiforme (GBM) in first or second relapse
    • Retrieved from, ASCO Meeting Abstracts
    • De Groot J.F., Prados M., Urquhart T., Robertson S., Yaron Y., Sorensen A.G., et al. A phase II study of XL184 in patients (pts) with progressive glioblastoma multiforme (GBM) in first or second relapse. Journal of Clinical Oncology 2009, 27(15s):2047. Retrieved from, ASCO Meeting Abstracts. http://meeting.ascopubs.org/cgi/content/abstract/27/15S/204.
    • (2009) Journal of Clinical Oncology , vol.27 , Issue.15 S , pp. 2047
    • De Groot, J.F.1    Prados, M.2    Urquhart, T.3    Robertson, S.4    Yaron, Y.5    Sorensen, A.G.6
  • 60
    • 79957472391 scopus 로고    scopus 로고
    • Evidence for label-retaining tumour-initiating cells in human glioblastoma
    • Retrieved from
    • Deleyrolle L.P., Harding A., Cato K., Siebzehnrubl F.A., Rahman M., Azari H., et al. Evidence for label-retaining tumour-initiating cells in human glioblastoma. Brain: A journal of neurology 2011, 134:1331-1343. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3097894&tool=pmcentrez&rendertype=abstract.
    • (2011) Brain: A journal of neurology , vol.134 , pp. 1331-1343
    • Deleyrolle, L.P.1    Harding, A.2    Cato, K.3    Siebzehnrubl, F.A.4    Rahman, M.5    Azari, H.6
  • 61
    • 77952294428 scopus 로고    scopus 로고
    • Small molecule kinase inhibitors in glioblastoma: A systematic review of clinical studies
    • De Witt Hamer P. Small molecule kinase inhibitors in glioblastoma: A systematic review of clinical studies. Neuro-Oncology 2010, 12(3):304-316.
    • (2010) Neuro-Oncology , vol.12 , Issue.3 , pp. 304-316
    • De Witt Hamer, P.1
  • 62
    • 58149380742 scopus 로고    scopus 로고
    • Stem cell concepts renew cancer research
    • Retrieved from
    • Dick J.E. Stem cell concepts renew cancer research. Blood 2008, 112:4793-4807. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/19064739.
    • (2008) Blood , vol.112 , pp. 4793-4807
    • Dick, J.E.1
  • 63
    • 64749093574 scopus 로고    scopus 로고
    • Association of reactive oxygen species levels and radioresistance in cancer stem cells
    • Diehn M., Cho R.W., Lobo N.A., Kalisky T., Dorie M.J., Kulp A.N., et al. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 2009, 458(7239):780-783.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 780-783
    • Diehn, M.1    Cho, R.W.2    Lobo, N.A.3    Kalisky, T.4    Dorie, M.J.5    Kulp, A.N.6
  • 64
    • 0037374550 scopus 로고    scopus 로고
    • Oligodendrogliomas result from the expression of an activated mutant epidermal growth factor receptor in a RAS transgenic mouse astrocytoma model
    • Retrieved from
    • Ding H., Shannon P., Lau N., Wu X., Roncari L., Baldwin R.L., et al. Oligodendrogliomas result from the expression of an activated mutant epidermal growth factor receptor in a RAS transgenic mouse astrocytoma model. Cancer Research 2003, 55:1106-1113. Retrieved from. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12615729.
    • (2003) Cancer Research , vol.55 , pp. 1106-1113
    • Ding, H.1    Shannon, P.2    Lau, N.3    Wu, X.4    Roncari, L.5    Baldwin, R.L.6
  • 65
    • 0242321829 scopus 로고    scopus 로고
    • The glial identity of neural stem cells
    • Retrieved from
    • Doetsch F. The glial identity of neural stem cells. Nature Neuroscience 2003, 6:1127-1134. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/14583753.
    • (2003) Nature Neuroscience , vol.6 , pp. 1127-1134
    • Doetsch, F.1
  • 66
    • 33746807790 scopus 로고    scopus 로고
    • Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas
    • Doherty L., Gigas D.C., Kesari S., Drappatz J., Kim R., Zimmerman J., et al. Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas. Neurology 2006, 67(1):156-158. 10.1212/01.wnl.0000223844.77636.29.
    • (2006) Neurology , vol.67 , Issue.1 , pp. 156-158
    • Doherty, L.1    Gigas, D.C.2    Kesari, S.3    Drappatz, J.4    Kim, R.5    Zimmerman, J.6
  • 67
    • 78651255671 scopus 로고    scopus 로고
    • Selective inhibition of PDGFR by imatinib elicits the sustained activation of ERK and downstream receptor signaling in malignant glioma cells
    • Dong Y., Jia L., Wang X., Tan X., Xu J., Deng Z., et al. Selective inhibition of PDGFR by imatinib elicits the sustained activation of ERK and downstream receptor signaling in malignant glioma cells. International Journal of Oncology 2011, 38(2):555-569. 10.3892/ijo.2010.861.
    • (2011) International Journal of Oncology , vol.38 , Issue.2 , pp. 555-569
    • Dong, Y.1    Jia, L.2    Wang, X.3    Tan, X.4    Xu, J.5    Deng, Z.6
  • 69
    • 0035810147 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
    • Druker B.J., Talpaz M., Resta D.J., Peng B., Buchdunger E., Ford J.M., et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. The New England Journal of Medicine 2001, 344(14):1031-1037.
    • (2001) The New England Journal of Medicine , vol.344 , Issue.14 , pp. 1031-1037
    • Druker, B.J.1    Talpaz, M.2    Resta, D.J.3    Peng, B.4    Buchdunger, E.5    Ford, J.M.6
  • 70
    • 84859847164 scopus 로고    scopus 로고
    • Emerging insights into the molecular and cellular basis of glioblastoma
    • Dunn G.P., Rinne M.L., Wykosky J., Genovese G., Quayle S.N., Dunn I.F., et al. Emerging insights into the molecular and cellular basis of glioblastoma. Genes & Development 2012, 26(8):756-784. 10.1101/gad.187922.112.
    • (2012) Genes & Development , vol.26 , Issue.8 , pp. 756-784
    • Dunn, G.P.1    Rinne, M.L.2    Wykosky, J.3    Genovese, G.4    Quayle, S.N.5    Dunn, I.F.6
  • 71
    • 84860577189 scopus 로고    scopus 로고
    • A DNA hypermethylation module for the stem/progenitor cell signature of cancer
    • Easwaran H., Johnstone S., Vanneste L., Ohm J., Mosbruger T., Wang Q., et al. A DNA hypermethylation module for the stem/progenitor cell signature of cancer. Genome Research 2012, 22:837-849. 10.1101/gr.131169.111.
    • (2012) Genome Research , vol.22 , pp. 837-849
    • Easwaran, H.1    Johnstone, S.2    Vanneste, L.3    Ohm, J.4    Mosbruger, T.5    Wang, Q.6
  • 72
    • 11144229294 scopus 로고    scopus 로고
    • Anti-epidermal growth factor receptor monoclonal antibody cetuximab augments radiation effects in glioblastoma multiforme in vitro and in vivo
    • Eller J.L., Longo S.L., Kyle M.M., Bassano D. Anti-epidermal growth factor receptor monoclonal antibody cetuximab augments radiation effects in glioblastoma multiforme in vitro and in vivo. Neurosurgery 2005, 56(1):155-162. 10.1227/01.NEU.0000145865.25689.55.
    • (2005) Neurosurgery , vol.56 , Issue.1 , pp. 155-162
    • Eller, J.L.1    Longo, S.L.2    Kyle, M.M.3    Bassano, D.4
  • 73
    • 0029135433 scopus 로고
    • The MMTV/c-myc transgene and p53 null alleles collaborate to induce T-cell lymphomas, but not mammary carcinomas in transgenic mice
    • Elson A., Deng C., Campos-Torres J., Donehower L.A., Leder P. The MMTV/c-myc transgene and p53 null alleles collaborate to induce T-cell lymphomas, but not mammary carcinomas in transgenic mice. Oncogene 1995, 11(1):181-190.
    • (1995) Oncogene , vol.11 , Issue.1 , pp. 181-190
    • Elson, A.1    Deng, C.2    Campos-Torres, J.3    Donehower, L.A.4    Leder, P.5
  • 74
    • 84865199671 scopus 로고    scopus 로고
    • Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas
    • Engler J.R., Robinson A.E., Smirnov I., Hodgson J.G., Berger M.S., Gupta N., et al. Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas. PloS One 2012, 7(8):e43339. 10.1371/journal.pone.0043339.
    • (2012) PloS One , vol.7 , Issue.8
    • Engler, J.R.1    Robinson, A.E.2    Smirnov, I.3    Hodgson, J.G.4    Berger, M.S.5    Gupta, N.6
  • 75
    • 0031789814 scopus 로고    scopus 로고
    • Neurogenesis in the adult human hippocampus
    • Retrieved from
    • Eriksson P.S., Perfilieva E., Bjork-Eriksson T., Alborn A.M., Nordborg C., Peterson D.A., et al. Neurogenesis in the adult human hippocampus. Nature Medicine 1998, 4:1313-1317. Retrieved from. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9809557.
    • (1998) Nature Medicine , vol.4 , pp. 1313-1317
    • Eriksson, P.S.1    Perfilieva, E.2    Bjork-Eriksson, T.3    Alborn, A.M.4    Nordborg, C.5    Peterson, D.A.6
  • 76
    • 34548596728 scopus 로고    scopus 로고
    • A dual phosphoinositide-3-kinase alpha/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma
    • Fan Q.-W., Cheng C.K., Nicolaides T.P., Hackett C.S., Knight Z.A., Shokat K.M., et al. A dual phosphoinositide-3-kinase alpha/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma. Cancer Research 2007, 67(17):7960-7965. 10.1158/0008-5472.CAN-07-2154.
    • (2007) Cancer Research , vol.67 , Issue.17 , pp. 7960-7965
    • Fan, Q.-W.1    Cheng, C.K.2    Nicolaides, T.P.3    Hackett, C.S.4    Knight, Z.A.5    Shokat, K.M.6
  • 77
    • 33646382364 scopus 로고    scopus 로고
    • A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma
    • Fan Q.-W., Knight Z.A., Goldenberg D.D., Yu W., Mostov K.E., Stokoe D., et al. A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma. Cancer cell 2006, 9(5):341-349. 10.1016/j.ccr.2006.03.029.
    • (2006) Cancer cell , vol.9 , Issue.5 , pp. 341-349
    • Fan, Q.-W.1    Knight, Z.A.2    Goldenberg, D.D.3    Yu, W.4    Mostov, K.E.5    Stokoe, D.6
  • 78
    • 79952111297 scopus 로고    scopus 로고
    • Targeting the RTK-PI3K-mTOR axis in malignant glioma: Overcoming resistance
    • Fan Q.-W., Weiss W.A. Targeting the RTK-PI3K-mTOR axis in malignant glioma: Overcoming resistance. Current Topics in Microbiology and Immunology 2010, 347:279-296. 10.1007/82_2010_67.
    • (2010) Current Topics in Microbiology and Immunology , vol.347 , pp. 279-296
    • Fan, Q.-W.1    Weiss, W.A.2
  • 80
    • 80053545678 scopus 로고    scopus 로고
    • Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy
    • Fathi A.T., Abdel-Wahab O. Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy. Advances in Hematology 2012, 2012(12):1-12.
    • (2012) Advances in Hematology , vol.2012 , Issue.12 , pp. 1-12
    • Fathi, A.T.1    Abdel-Wahab, O.2
  • 82
    • 78650019179 scopus 로고    scopus 로고
    • Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
    • Figueroa M.E., Abdel-Wahab O., Lu C., Ward P.S., Patel J., Shih A., et al. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 2010, 18(6):553-567. 10.1016/j.ccr.2010.11.015.
    • (2010) Cancer Cell , vol.18 , Issue.6 , pp. 553-567
    • Figueroa, M.E.1    Abdel-Wahab, O.2    Lu, C.3    Ward, P.S.4    Patel, J.5    Shih, A.6
  • 83
    • 77954563464 scopus 로고    scopus 로고
    • Hypoxia, inflammation, and the tumor microenvironment in metastatic disease
    • Finger E.C., Giaccia A.J. Hypoxia, inflammation, and the tumor microenvironment in metastatic disease. Cancer and Metastasis Reviews 2010, 29(2):285-293.
    • (2010) Cancer and Metastasis Reviews , vol.29 , Issue.2 , pp. 285-293
    • Finger, E.C.1    Giaccia, A.J.2
  • 84
    • 84884893986 scopus 로고    scopus 로고
    • Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake
    • Flavahan W.A., Wu Q., Hitomi M., Rahim N., Kim Y., Sloan A.E., et al. Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake. Nature Neuroscience 2013, 16:1373-1382.
    • (2013) Nature Neuroscience , vol.16 , pp. 1373-1382
    • Flavahan, W.A.1    Wu, Q.2    Hitomi, M.3    Rahim, N.4    Kim, Y.5    Sloan, A.E.6
  • 86
    • 0031853610 scopus 로고    scopus 로고
    • Platelet-derived growth factor induces chemotaxis of neuroepithelial stem cells
    • Retrieved from
    • Forsberg-Nilsson K., Behar T.N., Afrakhte M., Barker J.L., McKay R.D. Platelet-derived growth factor induces chemotaxis of neuroepithelial stem cells. Journal of Neuroscience Research 1998, 53:521-530. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/9726423.
    • (1998) Journal of Neuroscience Research , vol.53 , pp. 521-530
    • Forsberg-Nilsson, K.1    Behar, T.N.2    Afrakhte, M.3    Barker, J.L.4    McKay, R.D.5
  • 87
    • 84869878282 scopus 로고    scopus 로고
    • Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice
    • Friedmann-Morvinski D., Bushong E.A., Ke E., Soda Y., Marumoto T., Singer O., et al. Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice. Science 2012, 338:1080-1084. 10.1126/science.1226929.
    • (2012) Science , vol.338 , pp. 1080-1084
    • Friedmann-Morvinski, D.1    Bushong, E.A.2    Ke, E.3    Soda, Y.4    Marumoto, T.5    Singer, O.6
  • 88
    • 84858591526 scopus 로고    scopus 로고
    • In situ analysis of mutant EGFRs prevalent in glioblastoma multiforme reveals aberrant dimerization, activation, and differential response to anti-EGFR targeted therapy
    • Gajadhar A.S., Bogdanovic E., Muñoz D.M., Guha A. In situ analysis of mutant EGFRs prevalent in glioblastoma multiforme reveals aberrant dimerization, activation, and differential response to anti-EGFR targeted therapy. Molecular Cancer Research: MCR 2012, 10(3):428-440. 10.1158/1541-7786.MCR-11-0531.
    • (2012) Molecular Cancer Research: MCR , vol.10 , Issue.3 , pp. 428-440
    • Gajadhar, A.S.1    Bogdanovic, E.2    Muñoz, D.M.3    Guha, A.4
  • 90
    • 84883682803 scopus 로고    scopus 로고
    • Constitutive activation of signal transducer and activator of transcription 3 (STAT3) and nuclear factor B signaling in glioblastoma cancer stem cells regulates the notch pathway
    • Garner J.M., Fan M., Yang C.H., Du Z., Sims M., Davidoff A.M., et al. Constitutive activation of signal transducer and activator of transcription 3 (STAT3) and nuclear factor B signaling in glioblastoma cancer stem cells regulates the notch pathway. Journal of Biological Chemistry 2013, 288(36):26167-26176.
    • (2013) Journal of Biological Chemistry , vol.288 , Issue.36 , pp. 26167-26176
    • Garner, J.M.1    Fan, M.2    Yang, C.H.3    Du, Z.4    Sims, M.5    Davidoff, A.M.6
  • 91
    • 0034883605 scopus 로고    scopus 로고
    • Synergy between Hoxa1 and Hoxb1: The relationship between arch patterning and the generation of cranial neural crest
    • Retrieved from
    • Gavalas A., Trainor P., Ariza-McNaughton L., Krumlauf R. Synergy between Hoxa1 and Hoxb1: The relationship between arch patterning and the generation of cranial neural crest. Development (Cambridge, England) 2001, 128(15):3017-3027. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/11532923.
    • (2001) Development (Cambridge, England) , vol.128 , Issue.15 , pp. 3017-3027
    • Gavalas, A.1    Trainor, P.2    Ariza-McNaughton, L.3    Krumlauf, R.4
  • 92
    • 77954730533 scopus 로고    scopus 로고
    • Infiltrative patterns of glioblastoma spread detected via diffusion MRI after treatment with cediranib
    • Gerstner E.R., Chen P.-J., Wen P.Y., Jain R.K., Batchelor T.T., Sorensen G. Infiltrative patterns of glioblastoma spread detected via diffusion MRI after treatment with cediranib. Neuro-Oncology 2010, 12(5):466-472. 10.1093/neuonc/nop051.
    • (2010) Neuro-Oncology , vol.12 , Issue.5 , pp. 466-472
    • Gerstner, E.R.1    Chen, P.-J.2    Wen, P.Y.3    Jain, R.K.4    Batchelor, T.T.5    Sorensen, G.6
  • 93
    • 79959841782 scopus 로고    scopus 로고
    • Phase I trial with biomarker studies of vatalanib (PTK787) in patients with newly diagnosed glioblastoma treated with enzyme inducing anti-epileptic drugs and standard radiation and temozolomide
    • Gerstner E.R., Eichler A.F., Plotkin S.R., Drappatz J., Doyle C.L., Xu L., et al. Phase I trial with biomarker studies of vatalanib (PTK787) in patients with newly diagnosed glioblastoma treated with enzyme inducing anti-epileptic drugs and standard radiation and temozolomide. Journal of Neuro-Oncology 2011, 103(2):325-332. 10.1007/s11060-010-0390-7.
    • (2011) Journal of Neuro-Oncology , vol.103 , Issue.2 , pp. 325-332
    • Gerstner, E.R.1    Eichler, A.F.2    Plotkin, S.R.3    Drappatz, J.4    Doyle, C.L.5    Xu, L.6
  • 94
    • 84888045085 scopus 로고    scopus 로고
    • EGFR inhibitor BIBU induces apoptosis and defective autophagy in glioma cells
    • Ghildiyal R., Dixit D., Sen E. EGFR inhibitor BIBU induces apoptosis and defective autophagy in glioma cells. Molecular Carcinogenesis 2013, 52:970-982. 10.1002/mc.21938.
    • (2013) Molecular Carcinogenesis , vol.52 , pp. 970-982
    • Ghildiyal, R.1    Dixit, D.2    Sen, E.3
  • 95
    • 0142157702 scopus 로고    scopus 로고
    • Classification of human astrocytic gliomas on the basis of gene expression: A correlated group of genes with angiogenic activity emerges as a strong predictor of subtypes
    • Godard S., Getz G., Delorenzi M., Farmer P., Kobayashi H., Desbaillets I., et al. Classification of human astrocytic gliomas on the basis of gene expression: A correlated group of genes with angiogenic activity emerges as a strong predictor of subtypes. Cancer Research 2003, 63(20):6613-6625.
    • (2003) Cancer Research , vol.63 , Issue.20 , pp. 6613-6625
    • Godard, S.1    Getz, G.2    Delorenzi, M.3    Farmer, P.4    Kobayashi, H.5    Desbaillets, I.6
  • 98
    • 84876887800 scopus 로고    scopus 로고
    • MR imaging predictors of molecular profile and survival: Multi-institutional study of the TCGA glioblastoma data set
    • Gutman D.A., Cooper L.A.D., Hwang S.N., Holder C.A., Gao J., Aurora T.D., et al. MR imaging predictors of molecular profile and survival: Multi-institutional study of the TCGA glioblastoma data set. Radiology 2013, 267(2):560-569.
    • (2013) Radiology , vol.267 , Issue.2 , pp. 560-569
    • Gutman, D.A.1    Cooper, L.A.D.2    Hwang, S.N.3    Holder, C.A.4    Gao, J.5    Aurora, T.D.6
  • 100
    • 0030464161 scopus 로고    scopus 로고
    • Spinal cord oligodendrocytes develop from ventrally derived progenitor cells that express PDGF alpha-receptors
    • Retrieved from
    • Hall A., Giese N.A., Richardson W.D. Spinal cord oligodendrocytes develop from ventrally derived progenitor cells that express PDGF alpha-receptors. Development (Cambridge, England) 1996, 122:4085-4094. Retrieved from. http://discovery.ucl.ac.uk/109515/.
    • (1996) Development (Cambridge, England) , vol.122 , pp. 4085-4094
    • Hall, A.1    Giese, N.A.2    Richardson, W.D.3
  • 101
    • 0031317918 scopus 로고    scopus 로고
    • Preferential inhibition of glioblastoma cells with wild-type epidermal growth factor receptors by a novel tyrosine kinase inhibitor ethyl-2,5-dihydroxycinnamate
    • Han Y., Caday C.G., Umezawa K., Nanda A. Preferential inhibition of glioblastoma cells with wild-type epidermal growth factor receptors by a novel tyrosine kinase inhibitor ethyl-2,5-dihydroxycinnamate. Oncology Research 1997, 9:581-587.
    • (1997) Oncology Research , vol.9 , pp. 581-587
    • Han, Y.1    Caday, C.G.2    Umezawa, K.3    Nanda, A.4
  • 102
    • 69949114447 scopus 로고    scopus 로고
    • Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: A study of 1,010 diffuse gliomas
    • Hartmann C., Meyer J., Balss J., Capper D., Mueller W., Christians A., et al. Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: A study of 1,010 diffuse gliomas. Acta Neuropathologica 2009, 118(4):469-474.
    • (2009) Acta Neuropathologica , vol.118 , Issue.4 , pp. 469-474
    • Hartmann, C.1    Meyer, J.2    Balss, J.3    Capper, D.4    Mueller, W.5    Christians, A.6
  • 103
    • 84862317152 scopus 로고    scopus 로고
    • CD90 is identified as a marker for cancer stem cells in primary high-grade gliomas using tissue microarrays
    • He J., Liu Y., Zhu T., Zhu J., Dimeco F., Vescovi A.L., et al. CD90 is identified as a marker for cancer stem cells in primary high-grade gliomas using tissue microarrays. Molecular Cellular Proteomics: MCP 2011, 11:1-24. 10.1074/mcp.M111.010744.
    • (2011) Molecular Cellular Proteomics: MCP , vol.11 , pp. 1-24
    • He, J.1    Liu, Y.2    Zhu, T.3    Zhu, J.4    Dimeco, F.5    Vescovi, A.L.6
  • 104
    • 49949107386 scopus 로고    scopus 로고
    • The genetics of early telencephalon patterning: Some assembly required
    • Retrieved from
    • Hébert J.M., Fishell G. The genetics of early telencephalon patterning: Some assembly required. Nature Reviews Neuroscience 2008, 9:678-685. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2669317&tool=pmcentrez&rendertype=abstract.
    • (2008) Nature Reviews Neuroscience , vol.9 , pp. 678-685
    • Hébert, J.M.1    Fishell, G.2
  • 105
    • 69649103118 scopus 로고    scopus 로고
    • GFAP promoter driven transgenic expression of PDGFB in the mouse brain leads to glioblastoma in a Trp53 null background
    • Retrieved from
    • Hede S.-M., Hansson I., Afink G.B., Eriksson A., Nazarenko I., Andrae J., et al. GFAP promoter driven transgenic expression of PDGFB in the mouse brain leads to glioblastoma in a Trp53 null background. Glia 2009, 57:1143-1153. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/19115382.
    • (2009) Glia , vol.57 , pp. 1143-1153
    • Hede, S.-M.1    Hansson, I.2    Afink, G.B.3    Eriksson, A.4    Nazarenko, I.5    Andrae, J.6
  • 107
    • 42949175821 scopus 로고    scopus 로고
    • Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code
    • Retrieved from
    • Hochstim C., Deneen B., Lukaszewicz A., Zhou Q., Anderson D.J. Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code. Cell 2008, 133:510-522. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/18455991.
    • (2008) Cell , vol.133 , pp. 510-522
    • Hochstim, C.1    Deneen, B.2    Lukaszewicz, A.3    Zhou, Q.4    Anderson, D.J.5
  • 108
    • 70349630234 scopus 로고    scopus 로고
    • Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts
    • Hodgson J.G., Yeh R.-F., Ray A., Wang N.J., Smirnov I., Yu M., et al. Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts. Neuro-Oncology 2009, 11(5):477-487.
    • (2009) Neuro-Oncology , vol.11 , Issue.5 , pp. 477-487
    • Hodgson, J.G.1    Yeh, R.-F.2    Ray, A.3    Wang, N.J.4    Smirnov, I.5    Yu, M.6
  • 109
    • 0034020459 scopus 로고    scopus 로고
    • Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
    • Retrieved from
    • Holland E.C., Celestino J., Dai C., Schaefer L., Sawaya R.E., Fuller G.N. Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nature Genetics 2000, 25:55-57. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/10802656.
    • (2000) Nature Genetics , vol.25 , pp. 55-57
    • Holland, E.C.1    Celestino, J.2    Dai, C.3    Schaefer, L.4    Sawaya, R.E.5    Fuller, G.N.6
  • 110
    • 0032418416 scopus 로고    scopus 로고
    • A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice
    • Retrieved from
    • Holland Eric C., Hively W.P., DePinho R.A., Varmus H.E. A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice. Genes & Development 1998, 12:3675-3685. Retrieved from. http://www.genesdev.org/cgi/doi/10.1101/gad.12.23.3675.
    • (1998) Genes & Development , vol.12 , pp. 3675-3685
    • Holland, E.C.1    Hively, W.P.2    DePinho, R.A.3    Varmus, H.E.4
  • 111
    • 33645732616 scopus 로고    scopus 로고
    • Increased expression of CCAAT/enhancer binding protein β correlates with prognosis in glioma patients
    • Homma J., Yamanaka R., Yajima N., Tsuchiya N., Genkai N., Sano M., et al. Increased expression of CCAAT/enhancer binding protein β correlates with prognosis in glioma patients. Oncology Reports 2006, 15(3):595-601.
    • (2006) Oncology Reports , vol.15 , Issue.3 , pp. 595-601
    • Homma, J.1    Yamanaka, R.2    Yajima, N.3    Tsuchiya, N.4    Genkai, N.5    Sano, M.6
  • 112
    • 31144452918 scopus 로고    scopus 로고
    • TAZ: A beta-catenin-like molecule that regulates mesenchymal stem cell differentiation
    • Hong J.-H., Yaffe M.B. TAZ: A beta-catenin-like molecule that regulates mesenchymal stem cell differentiation. Cell Cycle 2006, 5(2):176-179.
    • (2006) Cell Cycle , vol.5 , Issue.2 , pp. 176-179
    • Hong, J.-H.1    Yaffe, M.B.2
  • 113
    • 78149249554 scopus 로고    scopus 로고
    • IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas
    • Houillier C., Wang X., Kaloshi G., Mokhtari K., Guillevin R., Laffaire J., et al. IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas. Neurology 2010, 75(17):1560-1566.
    • (2010) Neurology , vol.75 , Issue.17 , pp. 1560-1566
    • Houillier, C.1    Wang, X.2    Kaloshi, G.3    Mokhtari, K.4    Guillevin, R.5    Laffaire, J.6
  • 114
    • 18644377225 scopus 로고    scopus 로고
    • MTOR promotes survival and astrocytic characteristics induced by Pten/Akt signaling in glioblastoma1
    • Retrieved from
    • Hu X., Pandolfi P.P., Li Y., Koutcher J.A., Rosenblum M., Holland E.C. mTOR promotes survival and astrocytic characteristics induced by Pten/Akt signaling in glioblastoma1. Neoplasia 2005, 7:356-368. Retrieved from. http://www.ingentaselect.com/rpsv/cgi-bin/cgi?ini=xref&body=linker&reqdoi=10.1593/neo.04595.
    • (2005) Neoplasia , vol.7 , pp. 356-368
    • Hu, X.1    Pandolfi, P.P.2    Li, Y.3    Koutcher, J.A.4    Rosenblum, M.5    Holland, E.C.6
  • 115
    • 84862850415 scopus 로고    scopus 로고
    • Epigenetic control on cell fate choice in neural stem cells
    • Hu X.-L., Wang Y., Shen Q. Epigenetic control on cell fate choice in neural stem cells. Protein & Cell 2012, 3(4):278-290.
    • (2012) Protein & Cell , vol.3 , Issue.4 , pp. 278-290
    • Hu, X.-L.1    Wang, Y.2    Shen, Q.3
  • 116
    • 84878529371 scopus 로고    scopus 로고
    • Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain
    • Retrieved from
    • Hughes E.G., Kang S.H., Fukaya M., Bergles D.E. Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain. Nature Neuroscience 2013, 16:668-676. Retrieved from. http://www.nature.com/doifinder/10.1038/nn.3390.
    • (2013) Nature Neuroscience , vol.16 , pp. 668-676
    • Hughes, E.G.1    Kang, S.H.2    Fukaya, M.3    Bergles, D.E.4
  • 117
    • 77951599543 scopus 로고    scopus 로고
    • Targeting brain cancer: Advances in the molecular pathology of malignant glioma and medulloblastoma
    • Retrieved from
    • Huse J.T., Holland E.C. Targeting brain cancer: Advances in the molecular pathology of malignant glioma and medulloblastoma. Nature Reviews Cancer 2010, 10:319-331. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/20414201.
    • (2010) Nature Reviews Cancer , vol.10 , pp. 319-331
    • Huse, J.T.1    Holland, E.C.2
  • 118
    • 68349116524 scopus 로고    scopus 로고
    • IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas
    • Ichimura K., Pearson D.M., Kocialkowski S., Bäcklund L.M., Chan R., Jones D.T.W., et al. IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas. Neuro-Oncology 2009, 11(4):341-347.
    • (2009) Neuro-Oncology , vol.11 , Issue.4 , pp. 341-347
    • Ichimura, K.1    Pearson, D.M.2    Kocialkowski, S.3    Bäcklund, L.M.4    Chan, R.5    Jones, D.T.W.6
  • 119
    • 84871781182 scopus 로고    scopus 로고
    • Sustained activation of ERK1/2 MAPK in oligodendrocytes and schwann cells enhances myelin growth and stimulates oligodendrocyte progenitor expansion
    • Ishii A., Furusho M., Bansal R. Sustained activation of ERK1/2 MAPK in oligodendrocytes and schwann cells enhances myelin growth and stimulates oligodendrocyte progenitor expansion. The Journal of Neuroscience: The Official Journal of the Society for Neuroscience 2013, 33(1):175-186. 10.1523/JNEUROSCI.4403-12.2013.
    • (2013) The Journal of Neuroscience: The Official Journal of the Society for Neuroscience , vol.33 , Issue.1 , pp. 175-186
    • Ishii, A.1    Furusho, M.2    Bansal, R.3
  • 121
    • 78149492402 scopus 로고    scopus 로고
    • Trial of pazopanib (GW786034), an oral multi-targeted angiogenesis inhibitor, for adults with recurrent glioblastoma (North American Brain Tumor Consortium Study 06)
    • Retrieved from
    • Iwamoto F.M. trial of pazopanib (GW786034), an oral multi-targeted angiogenesis inhibitor, for adults with recurrent glioblastoma (North American Brain Tumor Consortium Study 06). Neuro-Oncology 2010, 12(8):855-861. Retrieved from. http://neuro-oncology.oxfordjournals.org/content/12/8/855.short.
    • (2010) Neuro-Oncology , vol.12 , Issue.8 , pp. 855-861
    • Iwamoto, F.M.1
  • 123
  • 124
  • 126
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • Jones P.A., Baylin S.B. The epigenomics of cancer. Cell 2007, 128(4):683-692. 10.1016/j.cell.2007.01.029.
    • (2007) Cell , vol.128 , Issue.4 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 127
    • 84864863728 scopus 로고    scopus 로고
    • MET signaling regulates glioblastoma stem cells
    • Joo K.M., Jin J., Kim E., Ho Kim K., Kim Y., Gu Kang B., et al. MET signaling regulates glioblastoma stem cells. Cancer Research 2012, 72:3828-3838. 10.1158/0008-5472.CAN-11-3760.
    • (2012) Cancer Research , vol.72 , pp. 3828-3838
    • Joo, K.M.1    Jin, J.2    Kim, E.3    Ho Kim, K.4    Kim, Y.5    Gu Kang, B.6
  • 128
    • 84866972099 scopus 로고    scopus 로고
    • Evaluation of tyrosine kinase inhibitor combinations for glioblastoma therapy
    • Joshi A.D., Loilome W., Siu I.-M., Tyler B., Gallia G.L., Riggins G.J. Evaluation of tyrosine kinase inhibitor combinations for glioblastoma therapy. PloS One 2012, 7(10):e44372. 10.1371/journal.pone.0044372.
    • (2012) PloS One , vol.7 , Issue.10
    • Joshi, A.D.1    Loilome, W.2    Siu, I.-M.3    Tyler, B.4    Gallia, G.L.5    Riggins, G.J.6
  • 131
  • 132
    • 1842865745 scopus 로고    scopus 로고
    • Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
    • Kanzawa T., Germano I.M., Komata T., Ito H., Kondo Y., Kondo S. Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. Cell Death and Differentiation 2004, 11(4):448-457. 10.1038/sj.cdd.4401359.
    • (2004) Cell Death and Differentiation , vol.11 , Issue.4 , pp. 448-457
    • Kanzawa, T.1    Germano, I.M.2    Komata, T.3    Ito, H.4    Kondo, Y.5    Kondo, S.6
  • 133
    • 84857666591 scopus 로고    scopus 로고
    • Astrocyte-specific expression patterns associated with the PDGF-induced glioma microenvironment
    • Katz A.M., Amankulor N.M., Pitter K., Helmy K., Squatrito M., Holland E.C. Astrocyte-specific expression patterns associated with the PDGF-induced glioma microenvironment. PloS One 2012, 7(2):e32453. 10.1371/journal.pone.0032453.
    • (2012) PloS One , vol.7 , Issue.2
    • Katz, A.M.1    Amankulor, N.M.2    Pitter, K.3    Helmy, K.4    Squatrito, M.5    Holland, E.C.6
  • 134
    • 84857013044 scopus 로고    scopus 로고
    • A mouse model of the most aggressive subgroup of human medulloblastoma
    • Kawauchi D., Robinson G., Uziel T., Gibson P., Rehg J., Gao C., et al. A mouse model of the most aggressive subgroup of human medulloblastoma. Cancer cell 2012, 21(2):168-180.
    • (2012) Cancer cell , vol.21 , Issue.2 , pp. 168-180
    • Kawauchi, D.1    Robinson, G.2    Uziel, T.3    Gibson, P.4    Rehg, J.5    Gao, C.6
  • 135
    • 31544442467 scopus 로고    scopus 로고
    • Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage
    • Kessaris N., Fogarty M., Iannarelli P., Grist M., Wegner M., Richardson W.D. Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage. Nature Neuroscience 2006, 9:173-179. 10.1038/nn1620.
    • (2006) Nature Neuroscience , vol.9 , pp. 173-179
    • Kessaris, N.1    Fogarty, M.2    Iannarelli, P.3    Grist, M.4    Wegner, M.5    Richardson, W.D.6
  • 137
    • 84865863019 scopus 로고    scopus 로고
    • K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
    • Khuong-Quang D.-A., Buczkowicz P., Rakopoulos P., Liu X.-Y., Fontebasso A.M., Bouffet E., et al. K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas. Acta Neuropathologica 2012, 124(3):439-447.
    • (2012) Acta Neuropathologica , vol.124 , Issue.3 , pp. 439-447
    • Khuong-Quang, D.-A.1    Buczkowicz, P.2    Rakopoulos, P.3    Liu, X.-Y.4    Fontebasso, A.M.5    Bouffet, E.6
  • 138
    • 0029018239 scopus 로고
    • Cloned multipotential precursors from the mouse cerebrum require FGF-2, whereas glial restricted precursors are stimulated with either FGF-2 or EGF
    • Retrieved from
    • Kilpatrick T.J., Bartlett P.F. Cloned multipotential precursors from the mouse cerebrum require FGF-2, whereas glial restricted precursors are stimulated with either FGF-2 or EGF. Journal of Neuroscience 1995, 15:3653-3661. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/7751935.
    • (1995) Journal of Neuroscience , vol.15 , pp. 3653-3661
    • Kilpatrick, T.J.1    Bartlett, P.F.2
  • 139
    • 84861789402 scopus 로고    scopus 로고
    • Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity
    • Kim Y., Kim E., Wu Q., Guryanova O., Hitomi M., Lathia J.D., et al. Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity. Genes & Development 2012, 26:1247-1262. 10.1101/gad.193565.112.
    • (2012) Genes & Development , vol.26 , pp. 1247-1262
    • Kim, Y.1    Kim, E.2    Wu, Q.3    Guryanova, O.4    Hitomi, M.5    Lathia, J.D.6
  • 140
    • 77949697909 scopus 로고    scopus 로고
    • Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice
    • Kioi M., Vogel H., Schultz G., Hoffman R.M., Harsh G.R., Brown J.M. Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice. The Journal of Clinical Investigation 2010, 120(3):694-705.
    • (2010) The Journal of Clinical Investigation , vol.120 , Issue.3 , pp. 694-705
    • Kioi, M.1    Vogel, H.2    Schultz, G.3    Hoffman, R.M.4    Harsh, G.R.5    Brown, J.M.6
  • 141
    • 77949458939 scopus 로고    scopus 로고
    • Identification of novel glial genes by single-cell transcriptional profiling of bergmann glial cells from mouse cerebellum
    • Koirala S., Corfas G. Identification of novel glial genes by single-cell transcriptional profiling of bergmann glial cells from mouse cerebellum. PLoS ONE 2010, 5:15. 10.1371/journal.pone.0009198.
    • (2010) PLoS ONE , vol.5 , pp. 15
    • Koirala, S.1    Corfas, G.2
  • 143
    • 0037069932 scopus 로고    scopus 로고
    • In vitro chemo- and radio-resistance in small cell lung cancer correlates with cell adhesion and constitutive activation of AKT and MAP kinase pathways
    • Kraus A.C., Ferber I., Bachmann S.-O., Specht H., Wimmel A., Gross M.W., et al. In vitro chemo- and radio-resistance in small cell lung cancer correlates with cell adhesion and constitutive activation of AKT and MAP kinase pathways. Oncogene 2002, 21(57):8683-8695.
    • (2002) Oncogene , vol.21 , Issue.57 , pp. 8683-8695
    • Kraus, A.C.1    Ferber, I.2    Bachmann, S.-O.3    Specht, H.4    Wimmel, A.5    Gross, M.W.6
  • 146
    • 44849089702 scopus 로고    scopus 로고
    • Pten haploinsufficiency accelerates formation of high-grade astrocytomas
    • Retrieved from
    • Kwon C.-H., Zhao D., Chen J., Alcantara S., Li Y., Burns D.K., et al. Pten haploinsufficiency accelerates formation of high-grade astrocytomas. Cancer Research 2008, 68:3286-3294. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2760841&tool=pmcentrez&rendertype=abstract.
    • (2008) Cancer Research , vol.68 , pp. 3286-3294
    • Kwon, C.-H.1    Zhao, D.2    Chen, J.3    Alcantara, S.4    Li, Y.5    Burns, D.K.6
  • 149
    • 77957736585 scopus 로고    scopus 로고
    • Wnts influence the timing and efficiency of oligodendrocyte precursor cell generation in the telencephalon
    • Retrieved from
    • Langseth A.J., Munji R.N., Choe Y., Huynh T., Pozniak C.D., Pleasure S.J. Wnts influence the timing and efficiency of oligodendrocyte precursor cell generation in the telencephalon. Journal of Neuroscience 2010, 30:13367-13372. Retrieved from. http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.1934-10.2010.
    • (2010) Journal of Neuroscience , vol.30 , pp. 13367-13372
    • Langseth, A.J.1    Munji, R.N.2    Choe, Y.3    Huynh, T.4    Pozniak, C.D.5    Pleasure, S.J.6
  • 150
    • 63549116173 scopus 로고    scopus 로고
    • Age-related myelin dynamics revealed by increased oligodendrogenesis and short internodes
    • Retrieved from
    • Lasiene J., Matsui A., Sawa Y., Wong F., Horner P.J. Age-related myelin dynamics revealed by increased oligodendrogenesis and short internodes. Aging Cell 2009, 8:201-213. Retrieved from. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703583/?tool=pubmed.
    • (2009) Aging Cell , vol.8 , pp. 201-213
    • Lasiene, J.1    Matsui, A.2    Sawa, Y.3    Wong, F.4    Horner, P.J.5
  • 151
    • 77956245743 scopus 로고    scopus 로고
    • Integrin alpha 6 regulates glioblastoma stem cells
    • Retrieved from
    • Lathia Justin D., Gallagher J., Heddleston J.M., Wang J., Eyler C.E., Macswords J., et al. Integrin alpha 6 regulates glioblastoma stem cells. Cell Stem Cell 2010, 6:421-432. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2884275&tool=pmcentrez&rendertype=abstract.
    • (2010) Cell Stem Cell , vol.6 , pp. 421-432
    • Lathia, J.D.1    Gallagher, J.2    Heddleston, J.M.3    Wang, J.4    Eyler, C.E.5    Macswords, J.6
  • 152
    • 80053430963 scopus 로고    scopus 로고
    • Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions
    • Lathia J.D., Hitomi M., Gallagher J., Gadani S.P., Adkins J., Vasanji A., et al. Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions. Cell Death Disease 2011, 2:e200. 10.1038/cddis.2011.80.
    • (2011) Cell Death Disease , vol.2
    • Lathia, J.D.1    Hitomi, M.2    Gallagher, J.3    Gadani, S.P.4    Adkins, J.5    Vasanji, A.6
  • 153
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by Polycomb in human embryonic stem cells
    • Retrieved from
    • Lee T.I., Jenner R.G., Boyer L.A., Guenther M.G., Levine S.S., Kumar R.M., et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 2006, 125:301-313. Retrieved from. http://discovery.ucl.ac.uk/7048/.
    • (2006) Cell , vol.125 , pp. 301-313
    • Lee, T.I.1    Jenner, R.G.2    Boyer, L.A.3    Guenther, M.G.4    Levine, S.S.5    Kumar, R.M.6
  • 154
    • 84869188311 scopus 로고    scopus 로고
    • Phase I/II study of sorafenib in combination with temsirolimus for recurrent glioblastoma or gliosarcoma: North American Brain Tumor Consortium study 05-02
    • Lee E.Q., Kuhn J., Lamborn K.R., Abrey L., DeAngelis L.M., Lieberman F., et al. Phase I/II study of sorafenib in combination with temsirolimus for recurrent glioblastoma or gliosarcoma: North American Brain Tumor Consortium study 05-02. Neuro-Oncology 2012, 14(12):1511-1518. 10.1093/neuonc/nos264.
    • (2012) Neuro-Oncology , vol.14 , Issue.12 , pp. 1511-1518
    • Lee, E.Q.1    Kuhn, J.2    Lamborn, K.R.3    Abrey, L.4    DeAngelis, L.M.5    Lieberman, F.6
  • 155
    • 33845926387 scopus 로고    scopus 로고
    • Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain
    • A. Lassman, Ed
    • Lee J.C., Vivanco I., Beroukhim R., Huang J.H.Y., Feng W.L., DeBiasi R.M., et al. Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain. PLoS Medicine 2006, 3(12):e485. A. Lassman, Ed.
    • (2006) PLoS Medicine , vol.3 , Issue.12
    • Lee, J.C.1    Vivanco, I.2    Beroukhim, R.3    Huang, J.H.Y.4    Feng, W.L.5    DeBiasi, R.M.6
  • 156
    • 79956361405 scopus 로고    scopus 로고
    • Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype
    • Retrieved from
    • Lei L., Sonabend A.M., Guarnieri P., Soderquist C., Ludwig T., Rosenfeld S., et al. Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype. PLoS ONE 2011, 6:e20041. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3100315&tool=pmcentrez&rendertype=abstract.
    • (2011) PLoS ONE , vol.6
    • Lei, L.1    Sonabend, A.M.2    Guarnieri, P.3    Soderquist, C.4    Ludwig, T.5    Rosenfeld, S.6
  • 157
    • 41149098966 scopus 로고    scopus 로고
    • TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway
    • Lei Q.-Y., Zhang H., Zhao B., Zha Z.-Y., Bai F., Pei X.-H., et al. TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway. Molecular and Cellular Biology 2008, 28(7):2426-2436.
    • (2008) Molecular and Cellular Biology , vol.28 , Issue.7 , pp. 2426-2436
    • Lei, Q.-Y.1    Zhang, H.2    Zhao, B.3    Zha, Z.-Y.4    Bai, F.5    Pei, X.-H.6
  • 158
    • 33751201534 scopus 로고    scopus 로고
    • Growth factor-dependent actions of PACAP on oligodendrocyte progenitor proliferation
    • Retrieved from
    • Lelievre V., Ghiani C.A., Seksenyan A., Gressens P., De Vellis J., Waschek J.A. Growth factor-dependent actions of PACAP on oligodendrocyte progenitor proliferation. Regulatory Peptides 2006, 137:58-66. Retrieved from. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16989910.
    • (2006) Regulatory Peptides , vol.137 , pp. 58-66
    • Lelievre, V.1    Ghiani, C.A.2    Seksenyan, A.3    Gressens, P.4    De Vellis, J.5    Waschek, J.A.6
  • 159
    • 84877785024 scopus 로고    scopus 로고
    • Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma
    • Lewis P.W., Müller M.M., Koletsky M.S., Cordero F., Lin S., Banaszynski L.A., et al. Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science 2013, 340(6134):857-861.
    • (2013) Science , vol.340 , Issue.6134 , pp. 857-861
    • Lewis, P.W.1    Müller, M.M.2    Koletsky, M.S.3    Cordero, F.4    Lin, S.5    Banaszynski, L.A.6
  • 160
    • 52149115126 scopus 로고    scopus 로고
    • ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling
    • Retrieved from
    • Li X., Huang Y., Jiang J., Frank S.J. ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling. Cellular Signalling 2008, 20:2145-2155. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2613789&tool=pmcentrez&rendertype=abstract.
    • (2008) Cellular Signalling , vol.20 , pp. 2145-2155
    • Li, X.1    Huang, Y.2    Jiang, J.3    Frank, S.J.4
  • 161
    • 79959971880 scopus 로고    scopus 로고
    • C-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype
    • Retrieved from
    • Li Y., Li A., Glas M., Lal B., Ying M., Sang Y., et al. c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype. Proceedings of the National Academy of Sciences of the United States of America 2011, 108:9951-9956. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3116406&tool=pmcentrez&rendertype=abstract.
    • (2011) Proceedings of the National Academy of Sciences of the United States of America , vol.108 , pp. 9951-9956
    • Li, Y.1    Li, A.2    Glas, M.3    Lal, B.4    Ying, M.5    Sang, Y.6
  • 163
    • 84862646896 scopus 로고    scopus 로고
    • Inhibition of mitochondria- and endoplasmic reticulum stress-mediated autophagy augments temozolomide-induced apoptosis in glioma cells
    • Lin C.-J., Lee C.-C., Shih Y.-L., Lin C.-H., Wang S.-H., Chen T.-H., et al. Inhibition of mitochondria- and endoplasmic reticulum stress-mediated autophagy augments temozolomide-induced apoptosis in glioma cells. PloS One 2012, 7(6):e38706. 10.1371/journal.pone.0038706.
    • (2012) PloS One , vol.7 , Issue.6
    • Lin, C.-J.1    Lee, C.-C.2    Shih, Y.-L.3    Lin, C.-H.4    Wang, S.-H.5    Chen, T.-H.6
  • 164
    • 67349108288 scopus 로고    scopus 로고
    • Oligodendrocyte progenitor cells can act as cell of origin for experimental glioma
    • Retrieved from
    • Lindberg N., Kastemar M., Olofsson T., Smits A., Uhrbom L. Oligodendrocyte progenitor cells can act as cell of origin for experimental glioma. Oncogene 2009, 28:2266-2275. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/19421151.
    • (2009) Oncogene , vol.28 , pp. 2266-2275
    • Lindberg, N.1    Kastemar, M.2    Olofsson, T.3    Smits, A.4    Uhrbom, L.5
  • 166
    • 52949119487 scopus 로고    scopus 로고
    • Antitumor activity of F90, an epidermal growth factor receptor tyrosine kinase inhibitor, on glioblastoma cell line SHG-44
    • Liu F.-J., Gui S.-B., Li C.-Z., Sun Z.-L., Zhang Y.-Z., Academy C. Antitumor activity of F90, an epidermal growth factor receptor tyrosine kinase inhibitor, on glioblastoma cell line SHG-44. Chinese Medical Journal 2008, 121(17):1702-1706.
    • (2008) Chinese Medical Journal , vol.121 , Issue.17 , pp. 1702-1706
    • Liu, F.-J.1    Gui, S.-B.2    Li, C.-Z.3    Sun, Z.-L.4    Zhang, Y.-Z.5    Academy, C.6
  • 167
    • 68849091778 scopus 로고    scopus 로고
    • NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas
    • Liu T.-J., Koul D., LaFortune T., Tiao N., Shen R.J., Maira S.-M., et al. NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas. Molecular Cancer Therapeutics 2009, 8(8):2204-2210. 10.1158/1535-7163.MCT-09-0160.
    • (2009) Molecular Cancer Therapeutics , vol.8 , Issue.8 , pp. 2204-2210
    • Liu, T.-J.1    Koul, D.2    LaFortune, T.3    Tiao, N.4    Shen, R.J.5    Maira, S.-M.6
  • 168
    • 79960809488 scopus 로고    scopus 로고
    • Mosaic analysis with double markers reveals tumor cell of origin in glioma
    • Liu C., Sage J.C., Miller M.R., Verhaak R.G.W., Hippenmeyer S., Vogel H., et al. Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell 2011, 146(2):209-221. 10.1016/j.cell.2011.06.014.
    • (2011) Cell , vol.146 , Issue.2 , pp. 209-221
    • Liu, C.1    Sage, J.C.2    Miller, M.R.3    Verhaak, R.G.W.4    Hippenmeyer, S.5    Vogel, H.6
  • 169
    • 33845671339 scopus 로고    scopus 로고
    • Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
    • Liu G., Yuan X., Zeng Z., Tunici P., Ng H., Abdulkadir I.R., et al. Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Molecular Cancer 2006, 5:67. 10.1186/1476-4598-5-67.
    • (2006) Molecular Cancer , vol.5 , pp. 67
    • Liu, G.1    Yuan, X.2    Zeng, Z.3    Tunici, P.4    Ng, H.5    Abdulkadir, I.R.6
  • 170
    • 84862605178 scopus 로고    scopus 로고
    • Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
    • Liu-Chittenden Y., Huang B., Shim J.S., Chen Q., Lee S.-J., Anders R.A., et al. Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes & Development 2012, 26(12):1300-1305.
    • (2012) Genes & Development , vol.26 , Issue.12 , pp. 1300-1305
    • Liu-Chittenden, Y.1    Huang, B.2    Shim, J.S.3    Chen, Q.4    Lee, S.-J.5    Anders, R.A.6
  • 171
    • 77952979261 scopus 로고    scopus 로고
    • EGFR-targeted therapy in malignant glioma: Novel aspects and mechanisms of drug resistance
    • Lo H.-W. EGFR-targeted therapy in malignant glioma: Novel aspects and mechanisms of drug resistance. Current Molecular Pharmacology 2010, 3(1):37-52.
    • (2010) Current Molecular Pharmacology , vol.3 , Issue.1 , pp. 37-52
    • Lo, H.-W.1
  • 173
    • 84863754907 scopus 로고    scopus 로고
    • VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex
    • Lu K.V., Chang J.P., Parachoniak C.A., Pandika M.M., Aghi M.K., Meyronet D., et al. VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex. Cancer Cell 2012, 22(1):21-35. 10.1016/j.ccr.2012.05.037.
    • (2012) Cancer Cell , vol.22 , Issue.1 , pp. 21-35
    • Lu, K.V.1    Chang, J.P.2    Parachoniak, C.A.3    Pandika, M.M.4    Aghi, M.K.5    Meyronet, D.6
  • 174
    • 84858796262 scopus 로고    scopus 로고
    • IDH mutation impairs histone demethylation and results in a block to cell differentiation
    • Lu C., Ward P.S., Kapoor G.S., Rohle D., Turcan S., Abdel-Wahab O., et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature 2013, 483(7390):474-478.
    • (2013) Nature , vol.483 , Issue.7390 , pp. 474-478
    • Lu, C.1    Ward, P.S.2    Kapoor, G.S.3    Rohle, D.4    Turcan, S.5    Abdel-Wahab, O.6
  • 176
  • 177
    • 0029959163 scopus 로고    scopus 로고
    • Patterning the vertebrate neuraxis
    • Retrieved from
    • Lumsden A., Krumlauf R. Patterning the vertebrate neuraxis. Science 1996, 274(5290):1109-1115. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/8895453.
    • (1996) Science , vol.274 , Issue.5290 , pp. 1109-1115
    • Lumsden, A.1    Krumlauf, R.2
  • 178
    • 10744230965 scopus 로고    scopus 로고
    • Sonic hedgehog is required for progenitor cell telencephalic stem cell niches
    • Machold R., Hayashi S., Rutlin M., Muzumdar M.D., Nery S., Corbin J.G., et al. Sonic hedgehog is required for progenitor cell telencephalic stem cell niches. Neuron 2003, 39:937-950.
    • (2003) Neuron , vol.39 , pp. 937-950
    • Machold, R.1    Hayashi, S.2    Rutlin, M.3    Muzumdar, M.D.4    Nery, S.5    Corbin, J.G.6
  • 179
    • 51049109033 scopus 로고    scopus 로고
    • Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity
    • Maira S.-M., Stauffer F., Brueggen J., Furet P., Schnell C., Fritsch C., et al. Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity. Molecular Cancer Therapeutics 2008, 7(7):1851-1863. 10.1158/1535-7163.MCT-08-0017.
    • (2008) Molecular Cancer Therapeutics , vol.7 , Issue.7 , pp. 1851-1863
    • Maira, S.-M.1    Stauffer, F.2    Brueggen, J.3    Furet, P.4    Schnell, C.5    Fritsch, C.6
  • 180
    • 84892839751 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition: What is the impact on breast cancer stem cells and drug resistance
    • Mallini P., Lennard T., Kirby J., Meeson A. Epithelial-to-mesenchymal transition: What is the impact on breast cancer stem cells and drug resistance. Cancer Treatment Reviews 2014, 40:341-348.
    • (2014) Cancer Treatment Reviews , vol.40 , pp. 341-348
    • Mallini, P.1    Lennard, T.2    Kirby, J.3    Meeson, A.4
  • 181
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani S.A., Guo W., Liao M.-J., Eaton E.N., Ayyanan A., Zhou A.Y., et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008, 133(4):704-715.
    • (2008) Cell , vol.133 , Issue.4 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.-J.3    Eaton, E.N.4    Ayyanan, A.5    Zhou, A.Y.6
  • 183
    • 58149330085 scopus 로고    scopus 로고
    • Development of a novel mouse glioma model using lentiviral vectors
    • Retrieved from
    • Marumoto T., Tashiro A., Friedmann-Morvinski D., Scadeng M., Soda Y., Gage F.H., et al. Development of a novel mouse glioma model using lentiviral vectors. Nature Medicine 2009, 15:110-116. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/19122659.
    • (2009) Nature Medicine , vol.15 , pp. 110-116
    • Marumoto, T.1    Tashiro, A.2    Friedmann-Morvinski, D.3    Scadeng, M.4    Soda, Y.5    Gage, F.H.6
  • 184
    • 77957351780 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis
    • Mazzoleni S., Politi L.S., Pala M., Cominelli M., Franzin A., Sergi Sergi L., et al. Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis. Cancer Research 2010, 70(19):7500-7513. 10.1158/0008-5472.CAN-10-2353.
    • (2010) Cancer Research , vol.70 , Issue.19 , pp. 7500-7513
    • Mazzoleni, S.1    Politi, L.S.2    Pala, M.3    Cominelli, M.4    Franzin, A.5    Sergi Sergi, L.6
  • 185
    • 79952217981 scopus 로고    scopus 로고
    • The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma
    • Mehta S., Huillard E., Kesari S., Maire C.L., Golebiowski D., Harrington E.P., et al. The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma. Cancer Cell 2011, 19(3):359-371.
    • (2011) Cancer Cell , vol.19 , Issue.3 , pp. 359-371
    • Mehta, S.1    Huillard, E.2    Kesari, S.3    Maire, C.L.4    Golebiowski, D.5    Harrington, E.P.6
  • 187
    • 18744368072 scopus 로고    scopus 로고
    • An essential role for a MEK-C/EBP pathway during growth factor-regulated cortical neurogenesis
    • Ménard C., Hein P., Paquin A., Savelson A., Yang X.M., Lederfein D., et al. An essential role for a MEK-C/EBP pathway during growth factor-regulated cortical neurogenesis. Neuron 2002, 36(4):597-610.
    • (2002) Neuron , vol.36 , Issue.4 , pp. 597-610
    • Ménard, C.1    Hein, P.2    Paquin, A.3    Savelson, A.4    Yang, X.M.5    Lederfein, D.6
  • 188
    • 34547098824 scopus 로고    scopus 로고
    • Mosaic organization of neural stem cells in the adult brain
    • Retrieved from
    • Merkle F.T., Mirzadeh Z., Alvarez-Buylla A. Mosaic organization of neural stem cells in the adult brain. Science 2007, 317:381-384. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/17615304.
    • (2007) Science , vol.317 , pp. 381-384
    • Merkle, F.T.1    Mirzadeh, Z.2    Alvarez-Buylla, A.3
  • 190
    • 36349000329 scopus 로고    scopus 로고
    • Low HER2-expressing glioblastomas are more often secondary to anaplastic transformation of low-grade glioma
    • Mineo J.-F., Bordron A., Baroncini M., Maurage C.-A., Ramirez C., Siminski R.-M., et al. Low HER2-expressing glioblastomas are more often secondary to anaplastic transformation of low-grade glioma. Journal of Neuro-Oncology 2007, 85(3):281-287. 10.1007/s11060-007-9424-1.
    • (2007) Journal of Neuro-Oncology , vol.85 , Issue.3 , pp. 281-287
    • Mineo, J.-F.1    Bordron, A.2    Baroncini, M.3    Maurage, C.-A.4    Ramirez, C.5    Siminski, R.-M.6
  • 191
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
    • Retrieved from
    • Mitsui K., Tokuzawa Y., Itoh H., Segawa K., Murakami M., Takahashi K., et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003, 113:631-642. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/12787504.
    • (2003) Cell , vol.113 , pp. 631-642
    • Mitsui, K.1    Tokuzawa, Y.2    Itoh, H.3    Segawa, K.4    Murakami, M.5    Takahashi, K.6
  • 193
  • 194
    • 77749252671 scopus 로고    scopus 로고
    • Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis
    • Retrieved from
    • Moransard M., Sawitzky M., Fontana A., Suter T. Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis. Glia 2010, 58:559-571. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/19941340.
    • (2010) Glia , vol.58 , pp. 559-571
    • Moransard, M.1    Sawitzky, M.2    Fontana, A.3    Suter, T.4
  • 195
    • 78049285307 scopus 로고    scopus 로고
    • Novel targeted agents for platelet-derived growth factor receptor and c-KIT in malignant gliomas
    • Morris P.G., Abrey L.E. Novel targeted agents for platelet-derived growth factor receptor and c-KIT in malignant gliomas. Targeted Oncology 2010, 5(3):193-200. 10.1007/s11523-010-0160-7.
    • (2010) Targeted Oncology , vol.5 , Issue.3 , pp. 193-200
    • Morris, P.G.1    Abrey, L.E.2
  • 196
    • 84879300467 scopus 로고    scopus 로고
    • Phase II open-label study of nintedanib in patients with recurrent glioblastoma multiforme
    • Muhic A., Poulsen H.S., Sorensen M., Grunnet K., Lassen U. Phase II open-label study of nintedanib in patients with recurrent glioblastoma multiforme. Journal of Neuro-Oncology 2013, 111(2):205-212. 10.1007/s11060-012-1009-y.
    • (2013) Journal of Neuro-Oncology , vol.111 , Issue.2 , pp. 205-212
    • Muhic, A.1    Poulsen, H.S.2    Sorensen, M.3    Grunnet, K.4    Lassen, U.5
  • 197
    • 0034865816 scopus 로고    scopus 로고
    • Human glioblastoma xenografts overexpressing a tumor-specific mutant epidermal growth factor receptor sensitized to cisplatin by the AG1478 tyrosine kinase inhibitor
    • Nagane M., Narita Y., Mishima K., Levitzki A., Burgess A.W., Cavenee W.K., et al. Human glioblastoma xenografts overexpressing a tumor-specific mutant epidermal growth factor receptor sensitized to cisplatin by the AG1478 tyrosine kinase inhibitor. Journal of Neurosurgery 2001, 95(3):472-479. 10.3171/jns.2001.95.3.0472.
    • (2001) Journal of Neurosurgery , vol.95 , Issue.3 , pp. 472-479
    • Nagane, M.1    Narita, Y.2    Mishima, K.3    Levitzki, A.4    Burgess, A.W.5    Cavenee, W.K.6
  • 198
    • 0033574767 scopus 로고    scopus 로고
    • Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300
    • Nakashima K. Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300. Science 1999, 284(5413):479-482.
    • (1999) Science , vol.284 , Issue.5413 , pp. 479-482
    • Nakashima, K.1
  • 199
    • 84874593624 scopus 로고    scopus 로고
    • Effects of dual targeting of tumor cells and stroma in human glioblastoma xenografts with a tyrosine kinase inhibitor against c-MET and VEGFR2
    • Navis A.C., Bourgonje A., Wesseling P., Wright A., Hendriks W., Verrijp K., et al. Effects of dual targeting of tumor cells and stroma in human glioblastoma xenografts with a tyrosine kinase inhibitor against c-MET and VEGFR2. PloS One 2013, 8(3):e58262. 10.1371/journal.pone.0058262.
    • (2013) PloS One , vol.8 , Issue.3
    • Navis, A.C.1    Bourgonje, A.2    Wesseling, P.3    Wright, A.4    Hendriks, W.5    Verrijp, K.6
  • 200
    • 79954517042 scopus 로고    scopus 로고
    • Brain abnormalities and glioma-like lesions in mice overexpressing the long isoform of PDGF-A in astrocytic cells
    • Nazarenko I., Hedrén A., Sjödin H., Orrego A., Andrae J., Afink G.B., et al. Brain abnormalities and glioma-like lesions in mice overexpressing the long isoform of PDGF-A in astrocytic cells. PLoS ONE 2011, 6:14. 10.1371/journal.pone.0018303.
    • (2011) PLoS ONE , vol.6 , pp. 14
    • Nazarenko, I.1    Hedrén, A.2    Sjödin, H.3    Orrego, A.4    Andrae, J.5    Afink, G.B.6
  • 201
    • 79959795987 scopus 로고    scopus 로고
    • Phase II study of sunitinib malate in patients with recurrent high-grade glioma
    • Neyns B., Sadones J., Chaskis C., Dujardin M., Everaert H., Lv S., et al. Phase II study of sunitinib malate in patients with recurrent high-grade glioma. Journal of Neuro-Oncology 2011, 103(3):491-501. 10.1007/s11060-010-0402-7.
    • (2011) Journal of Neuro-Oncology , vol.103 , Issue.3 , pp. 491-501
    • Neyns, B.1    Sadones, J.2    Chaskis, C.3    Dujardin, M.4    Everaert, H.5    Lv, S.6
  • 202
    • 84867854266 scopus 로고    scopus 로고
    • A dose escalation trial for the combination of erlotinib and sirolimus for recurrent malignant gliomas
    • Nghiemphu P.L., Lai A., Green R.M., Reardon D.A., Cloughesy T. A dose escalation trial for the combination of erlotinib and sirolimus for recurrent malignant gliomas. Journal of Neuro-Oncology 2012, 110(2):245-250. 10.1007/s11060-012-0960-y.
    • (2012) Journal of Neuro-Oncology , vol.110 , Issue.2 , pp. 245-250
    • Nghiemphu, P.L.1    Lai, A.2    Green, R.M.3    Reardon, D.A.4    Cloughesy, T.5
  • 204
    • 0030063699 scopus 로고    scopus 로고
    • Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain
    • Nishiyama A., Lin X.H., Giese N., Heldin C.H., Stallcup W.B. Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain. Journal of Neuroscience Research 1996, 43:299-314. 10.1002/(SICI)1097-4547(19960201)43:3<299::AID-JNR5>3.0.CO;2-E.
    • (1996) Journal of Neuroscience Research , vol.43 , pp. 299-314
    • Nishiyama, A.1    Lin, X.H.2    Giese, N.3    Heldin, C.H.4    Stallcup, W.B.5
  • 206
    • 77952108366 scopus 로고    scopus 로고
    • Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
    • Noushmehr H., Weisenberger D.J., Diefes K., Phillips H.S., Pujara K., Berman B.P., et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 2010, 17(5):510-522.
    • (2010) Cancer Cell , vol.17 , Issue.5 , pp. 510-522
    • Noushmehr, H.1    Weisenberger, D.J.2    Diefes, K.3    Phillips, H.S.4    Pujara, K.5    Berman, B.P.6
  • 207
    • 32944457518 scopus 로고    scopus 로고
    • MTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt
    • O'Reilly K.E., Rojo F., She Q.-B., Solit D., Mills G.B., Smith D., et al. mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt. Cancer Research 2006, 66(3):1500-1508. 10.1158/0008-5472.CAN-05-2925.
    • (2006) Cancer Research , vol.66 , Issue.3 , pp. 1500-1508
    • O'Reilly, K.E.1    Rojo, F.2    She, Q.-B.3    Solit, D.4    Mills, G.B.5    Smith, D.6
  • 208
    • 34147096333 scopus 로고    scopus 로고
    • Hepatocyte growth factor (HGF) promotes oligodendrocyte progenitor cell proliferation and inhibits its differentiation during postnatal development in the rat
    • Retrieved from
    • Ohya W., Funakoshi H., Kurosawa T., Nakamura T. Hepatocyte growth factor (HGF) promotes oligodendrocyte progenitor cell proliferation and inhibits its differentiation during postnatal development in the rat. Brain Research 2007, 1147:51-65. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/17382307.
    • (2007) Brain Research , vol.1147 , pp. 51-65
    • Ohya, W.1    Funakoshi, H.2    Kurosawa, T.3    Nakamura, T.4
  • 209
    • 84870804965 scopus 로고    scopus 로고
    • Biomarkers classification and therapeutic decision-making for malignant gliomas
    • Olar A., Aldape K.D. Biomarkers classification and therapeutic decision-making for malignant gliomas. Current Treatment Options in Oncology 2012, 13:1-20. 10.1007/s11864-012-0210-8.
    • (2012) Current Treatment Options in Oncology , vol.13 , pp. 1-20
    • Olar, A.1    Aldape, K.D.2
  • 210
    • 60649106195 scopus 로고    scopus 로고
    • Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
    • Pàez-Ribes M., Allen E., Hudock J., Takeda T., Okuyama H., Viñals F., et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 2009, 15(3):220-231.
    • (2009) Cancer Cell , vol.15 , Issue.3 , pp. 220-231
    • Pàez-Ribes, M.1    Allen, E.2    Hudock, J.3    Takeda, T.4    Okuyama, H.5    Viñals, F.6
  • 211
    • 0035863399 scopus 로고    scopus 로고
    • A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles
    • Paglin S., Hollister T., Delohery T., Hackett N., McMahill M., Sphicas E., et al. A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. Cancer Research 2001, 61(2):439-444.
    • (2001) Cancer Research , vol.61 , Issue.2 , pp. 439-444
    • Paglin, S.1    Hollister, T.2    Delohery, T.3    Hackett, N.4    McMahill, M.5    Sphicas, E.6
  • 212
    • 27944475835 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein phosphorylation biases cortical precursors to generate neurons rather than astrocytes in vivo
    • Paquin A. CCAAT/enhancer-binding protein phosphorylation biases cortical precursors to generate neurons rather than astrocytes in vivo. The Journal of Neuroscience: The Official Journal of the Society for Neuroscience 2005, 25(46):10747-10758.
    • (2005) The Journal of Neuroscience: The Official Journal of the Society for Neuroscience , vol.25 , Issue.46 , pp. 10747-10758
    • Paquin, A.1
  • 213
    • 52949127312 scopus 로고    scopus 로고
    • An integrated genomic analysis of human glioblastoma multiforme
    • Retrieved from
    • Parsons D.W., Jones S., Zhang X., Lin J.C.-H., Leary R.J., Angenendt P., et al. An integrated genomic analysis of human glioblastoma multiforme. Science 2008, 321:1807-1812. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/18772396.
    • (2008) Science , vol.321 , pp. 1807-1812
    • Parsons, D.W.1    Jones, S.2    Zhang, X.3    Lin, J.C.-H.4    Leary, R.J.5    Angenendt, P.6
  • 215
    • 78650002007 scopus 로고    scopus 로고
    • Non-stem cell origin for oligodendroglioma
    • Retrieved from
    • Persson A.I., Petritsch C., Swartling F.J., Itsara M., Sim F.J., Auvergne R., et al. Non-stem cell origin for oligodendroglioma. Cancer Cell 2010, 18:669-682. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3031116&tool=pmcentrez&rendertype=abstract.
    • (2010) Cancer Cell , vol.18 , pp. 669-682
    • Persson, A.I.1    Petritsch, C.2    Swartling, F.J.3    Itsara, M.4    Sim, F.J.5    Auvergne, R.6
  • 216
    • 34547210748 scopus 로고    scopus 로고
    • Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain
    • Retrieved from
    • Petryniak M.A., Potter G.B., Rowitch D.H., Rubenstein J.L.R. Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain. Neuron 2007, 55:417-433. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2039927&tool=pmcentrez&rendertype=abstract.
    • (2007) Neuron , vol.55 , pp. 417-433
    • Petryniak, M.A.1    Potter, G.B.2    Rowitch, D.H.3    Rubenstein, J.L.R.4
  • 217
    • 84882247189 scopus 로고    scopus 로고
    • PDGFRA amplification is common in pediatric and adult high-grade astrocytomas and identifies a poor prognostic group in IDH1 mutant glioblastoma
    • Phillips J.J., Aranda D., Ellison D.W., Judkins A.R., Croul S.E., Brat D.J., et al. PDGFRA amplification is common in pediatric and adult high-grade astrocytomas and identifies a poor prognostic group in IDH1 mutant glioblastoma. Brain Pathology 2013, 23(5):565-573.
    • (2013) Brain Pathology , vol.23 , Issue.5 , pp. 565-573
    • Phillips, J.J.1    Aranda, D.2    Ellison, D.W.3    Judkins, A.R.4    Croul, S.E.5    Brat, D.J.6
  • 218
    • 33644820339 scopus 로고    scopus 로고
    • Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
    • Phillips H.S., Kharbanda S., Chen R., Forrest W.F., Soriano R.H., Wu T.D., et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 2006, 9(3):157-173. 10.1016/j.ccr.2006.02.019.
    • (2006) Cancer Cell , vol.9 , Issue.3 , pp. 157-173
    • Phillips, H.S.1    Kharbanda, S.2    Chen, R.3    Forrest, W.F.4    Soriano, R.H.5    Wu, T.D.6
  • 220
    • 84868035933 scopus 로고    scopus 로고
    • Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype
    • Piao Y., Liang J., Holmes L., Zurita A.J., Henry V., Heymach J.V., et al. Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype. Neuro-Oncology 2012, 14(11):1379-1392.
    • (2012) Neuro-Oncology , vol.14 , Issue.11 , pp. 1379-1392
    • Piao, Y.1    Liang, J.2    Holmes, L.3    Zurita, A.J.4    Henry, V.5    Heymach, J.V.6
  • 223
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • Polyak K., Weinberg R.A. Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits. Nature Reviews. Cancer 2009, 9(4):265-273.
    • (2009) Nature Reviews. Cancer , vol.9 , Issue.4 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 224
    • 84863230465 scopus 로고    scopus 로고
    • Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR
    • Prahallad A., Sun C., Huang S., Di Nicolantonio F., Salazar R., Zecchin D., et al. Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR. Nature 2012, 483(7387):100-103. 10.1038/nature10868.
    • (2012) Nature , vol.483 , Issue.7387 , pp. 100-103
    • Prahallad, A.1    Sun, C.2    Huang, S.3    Di Nicolantonio, F.4    Salazar, R.5    Zecchin, D.6
  • 226
    • 20144387679 scopus 로고    scopus 로고
    • Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation
    • Retrieved from
    • Purow B.W., Haque R.M., Noel M.W., Su Q., Burdick M.J., Lee J., et al. Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation. Cancer Research 2005, 65:2353-2363. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/15781650.
    • (2005) Cancer Research , vol.65 , pp. 2353-2363
    • Purow, B.W.1    Haque, R.M.2    Noel, M.W.3    Su, Q.4    Burdick, M.J.5    Lee, J.6
  • 228
    • 0020538298 scopus 로고
    • A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium
    • Retrieved from
    • Raff M.C., Miller R.H., Noble M. A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium. Nature 1983, 303:390-396. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/6304520.
    • (1983) Nature , vol.303 , pp. 390-396
    • Raff, M.C.1    Miller, R.H.2    Noble, M.3
  • 229
    • 75749122223 scopus 로고    scopus 로고
    • A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy
    • Retrieved from
    • Raizer J.J., Abrey L.E. A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy. Neuro-Oncology 2010, 12(1):95-103. Retrieved from. http://neuro-oncology.oxfordjournals.org/content/12/1/95.short.
    • (2010) Neuro-Oncology , vol.12 , Issue.1 , pp. 95-103
    • Raizer, J.J.1    Abrey, L.E.2
  • 230
    • 0025096007 scopus 로고
    • Principles of neural cell migration
    • Rakic P. Principles of neural cell migration. Experientia 1990, 46(9):882-891.
    • (1990) Experientia , vol.46 , Issue.9 , pp. 882-891
    • Rakic, P.1
  • 231
    • 33644877965 scopus 로고    scopus 로고
    • Disruption of parallel and converging signaling pathways contributes to the synergistic antitumor effects of simultaneous mTOR and EGFR inhibition in GBM cells
    • Rao R.D., Mladek A.C., Lamont J.D., Goble J.M., Erlichman C., James C.D., et al. Disruption of parallel and converging signaling pathways contributes to the synergistic antitumor effects of simultaneous mTOR and EGFR inhibition in GBM cells. Neoplasia 2005, 7(10):921-929. 10.1593/neo.05361.
    • (2005) Neoplasia , vol.7 , Issue.10 , pp. 921-929
    • Rao, R.D.1    Mladek, A.C.2    Lamont, J.D.3    Goble, J.M.4    Erlichman, C.5    James, C.D.6
  • 232
    • 77957993803 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 positive glioblastoma cells show brain tumor stem cell capacity
    • Retrieved from
    • Rasper M., Schäfer A., Piontek G., Teufel J., Brockhoff G., Ringel F., et al. Aldehyde dehydrogenase 1 positive glioblastoma cells show brain tumor stem cell capacity. Neuro-Oncology 2010, 12:1024-1033. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3018920&tool=pmcentrez&rendertype=abstract.
    • (2010) Neuro-Oncology , vol.12 , pp. 1024-1033
    • Rasper, M.1    Schäfer, A.2    Piontek, G.3    Teufel, J.4    Brockhoff, G.5    Ringel, F.6
  • 233
    • 84875800035 scopus 로고    scopus 로고
    • In vivo c-Met pathway inhibition depletes human glioma xenografts of tumor-propagating stem-like cells
    • Rath P., Lal B., Ajala O., Li Y., Xia S., Kim J., et al. In vivo c-Met pathway inhibition depletes human glioma xenografts of tumor-propagating stem-like cells. Translational Oncology 2013, 6(2):104-111.
    • (2013) Translational Oncology , vol.6 , Issue.2 , pp. 104-111
    • Rath, P.1    Lal, B.2    Ajala, O.3    Li, Y.4    Xia, S.5    Kim, J.6
  • 235
    • 84863796631 scopus 로고    scopus 로고
    • Phase I study of AEE788, a novel multitarget inhibitor of ErbB- and VEGF-receptor-family tyrosine kinases, in recurrent glioblastoma patients
    • Reardon David A., Conrad C.A., Cloughesy T., Prados M.D., Friedman H.S., Aldape K.D., et al. Phase I study of AEE788, a novel multitarget inhibitor of ErbB- and VEGF-receptor-family tyrosine kinases, in recurrent glioblastoma patients. Cancer Chemotherapy and Pharmacology 2012, 69(6):1507-1518. 10.1007/s00280-012-1854-6.
    • (2012) Cancer Chemotherapy and Pharmacology , vol.69 , Issue.6 , pp. 1507-1518
    • Reardon, D.A.1    Conrad, C.A.2    Cloughesy, T.3    Prados, M.D.4    Friedman, H.S.5    Aldape, K.D.6
  • 237
    • 71649102124 scopus 로고    scopus 로고
    • Multicentre phase II studies evaluating imatinib plus hydroxyurea in patients with progressive glioblastoma
    • Reardon D.A., Dresemann G., Taillibert S., Campone M., van den Bent M., Clement P., et al. Multicentre phase II studies evaluating imatinib plus hydroxyurea in patients with progressive glioblastoma. British Journal of Cancer 2009, 101(12):1995-2004. 10.1038/sj.bjc.6605411.
    • (2009) British Journal of Cancer , vol.101 , Issue.12 , pp. 1995-2004
    • Reardon, D.A.1    Dresemann, G.2    Taillibert, S.3    Campone, M.4    van den Bent, M.5    Clement, P.6
  • 239
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • Retrieved from
    • Reya T., Morrison S.J., Clarke M.F., Weissman I.L. Stem cells, cancer, and cancer stem cells. Nature 2001, 414:105-111. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/11689955.
    • (2001) Nature , vol.414 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 240
    • 40749101512 scopus 로고    scopus 로고
    • Transcription-dependent epidermal growth factor receptor activation by hepatocyte growth factor
    • Reznik T.E., Sang Y., Ma Y., Abounader R., Rosen E.M., Xia S., et al. Transcription-dependent epidermal growth factor receptor activation by hepatocyte growth factor. Molecular Cancer Research: MCR 2008, 6(1):139-150. 10.1158/1541-7786.MCR-07-0236.
    • (2008) Molecular Cancer Research: MCR , vol.6 , Issue.1 , pp. 139-150
    • Reznik, T.E.1    Sang, Y.2    Ma, Y.3    Abounader, R.4    Rosen, E.M.5    Xia, S.6
  • 241
    • 78650153633 scopus 로고    scopus 로고
    • Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells
    • Retrieved from
    • Ricci-Vitiani L., Pallini R., Biffoni M., Todaro M., Invernici G., Cenci T., et al. Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells. Nature 2010, 468:824-828. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/21102434.
    • (2010) Nature , vol.468 , pp. 824-828
    • Ricci-Vitiani, L.1    Pallini, R.2    Biffoni, M.3    Todaro, M.4    Invernici, G.5    Cenci, T.6
  • 242
    • 0035884608 scopus 로고    scopus 로고
    • Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis
    • Rickman D.S., Bobek M.P., Misek D.E., Kuick R., Blaivas M., Kurnit D.M., et al. Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis. Cancer Research 2001, 61(18):6885-6891.
    • (2001) Cancer Research , vol.61 , Issue.18 , pp. 6885-6891
    • Rickman, D.S.1    Bobek, M.P.2    Misek, D.E.3    Kuick, R.4    Blaivas, M.5    Kurnit, D.M.6
  • 243
    • 13444257366 scopus 로고    scopus 로고
    • Antiangiogenic and antitumor activity of a selective PDGFR tyrosine kinase inhibitor, CP-673,451
    • Retrieved from
    • Roberts W.G., Whalen P.M., Soderstrom E., Moraski G., Lyssikatos J.P., Wang H.-F., et al. Antiangiogenic and antitumor activity of a selective PDGFR tyrosine kinase inhibitor, CP-673,451. Cancer Research 2005, 65(3):957-966. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/15705896.
    • (2005) Cancer Research , vol.65 , Issue.3 , pp. 957-966
    • Roberts, W.G.1    Whalen, P.M.2    Soderstrom, E.3    Moraski, G.4    Lyssikatos, J.P.5    Wang, H.-F.6
  • 244
    • 79952758949 scopus 로고    scopus 로고
    • Activated MEK cooperates with Ink4a/Arf loss or Akt activation to induce gliomas in vivo
    • Retrieved from
    • Robinson J.P., Vanbrocklin M.W., Lastwika K.J., McKinney A.J., Brandner S., Holmen S.L. Activated MEK cooperates with Ink4a/Arf loss or Akt activation to induce gliomas in vivo. Oncogene 2011, 30:1341-1350. Retrieved from. http://discovery.ucl.ac.uk/441249/.
    • (2011) Oncogene , vol.30 , pp. 1341-1350
    • Robinson, J.P.1    Vanbrocklin, M.W.2    Lastwika, K.J.3    McKinney, A.J.4    Brandner, S.5    Holmen, S.L.6
  • 245
    • 84877632013 scopus 로고    scopus 로고
    • An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells
    • Rohle D., Popovici-Muller J., Palaskas N., Turcan S., Grommes C., Campos C., et al. An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science 2013, 340(6132):626-630.
    • (2013) Science , vol.340 , Issue.6132 , pp. 626-630
    • Rohle, D.1    Popovici-Muller, J.2    Palaskas, N.3    Turcan, S.4    Grommes, C.5    Campos, C.6
  • 246
    • 78049274170 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and mammalian target of rapamycin as therapeutic targets in malignant glioma: Current clinical status and perspectives
    • Ronellenfitsch M.W., Steinbach J.P., Wick W. Epidermal growth factor receptor and mammalian target of rapamycin as therapeutic targets in malignant glioma: Current clinical status and perspectives. Targeted Oncology 2010, 5(3):183-191. 10.1007/s11523-010-0154-5.
    • (2010) Targeted Oncology , vol.5 , Issue.3 , pp. 183-191
    • Ronellenfitsch, M.W.1    Steinbach, J.P.2    Wick, W.3
  • 247
    • 84891810705 scopus 로고    scopus 로고
    • A high Notch pathway activation predicts response to γ secretase inhibitors in proneural subtype of glioma tumor initiating cells
    • Saito N., Fu J., Zheng S., Yao J., Wang S., Liu D.D., et al. A high Notch pathway activation predicts response to γ secretase inhibitors in proneural subtype of glioma tumor initiating cells. Stem Cells 2014, 32:301-312.
    • (2014) Stem Cells , vol.32 , pp. 301-312
    • Saito, N.1    Fu, J.2    Zheng, S.3    Yao, J.4    Wang, S.5    Liu, D.D.6
  • 249
    • 80054998431 scopus 로고    scopus 로고
    • Corridors of migrating neurons in the human brain and their decline during infancy
    • Sanai N., Nguyen T., Ihrie R.A., Mirzadeh Z., Tsai H.-H., Wong M., et al. Corridors of migrating neurons in the human brain and their decline during infancy. Nature 2011, 478:1-6. 10.1038/nature10487.
    • (2011) Nature , vol.478 , pp. 1-6
    • Sanai, N.1    Nguyen, T.2    Ihrie, R.A.3    Mirzadeh, Z.4    Tsai, H.-H.5    Wong, M.6
  • 250
    • 84880747370 scopus 로고    scopus 로고
    • Comparison of glioma stem cells to neural stem cells from the adult human brain identifies dysregulated Wnt- signaling and a fingerprint associated with clinical outcome
    • Sandberg C.J., Altschuler G., Jeong J., Strømme K.K., Stangeland B., Murrell W., et al. Comparison of glioma stem cells to neural stem cells from the adult human brain identifies dysregulated Wnt- signaling and a fingerprint associated with clinical outcome. Experimental Cell Research 2013, 319:1-14. 10.1016/j.yexcr.2013.06.004.
    • (2013) Experimental Cell Research , vol.319 , pp. 1-14
    • Sandberg, C.J.1    Altschuler, G.2    Jeong, J.3    Strømme, K.K.4    Stangeland, B.5    Murrell, W.6
  • 254
    • 84866480031 scopus 로고    scopus 로고
    • D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function
    • Sasaki M., Knobbe C.B., Itsumi M., Elia A.J., Harris I.S., Chio I.I.C., et al. D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes & Development 2012, 26(18):2038-2049.
    • (2012) Genes & Development , vol.26 , Issue.18 , pp. 2038-2049
    • Sasaki, M.1    Knobbe, C.B.2    Itsumi, M.3    Elia, A.J.4    Harris, I.S.5    Chio, I.I.C.6
  • 255
    • 84865520089 scopus 로고    scopus 로고
    • IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
    • Sasaki M., Knobbe C.B., Munger J.C., Lind E.F., Brenner D., Brüstle A., et al. IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics. Nature 2013, 488(7413):656-659.
    • (2013) Nature , vol.488 , Issue.7413 , pp. 656-659
    • Sasaki, M.1    Knobbe, C.B.2    Munger, J.C.3    Lind, E.F.4    Brenner, D.5    Brüstle, A.6
  • 257
    • 84862777348 scopus 로고    scopus 로고
    • Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
    • Schwartzentruber J., Korshunov A., Liu X.-Y., Jones D.T.W., Pfaff E., Jacob K., et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 2012, 482(7384):226-231.
    • (2012) Nature , vol.482 , Issue.7384 , pp. 226-231
    • Schwartzentruber, J.1    Korshunov, A.2    Liu, X.-Y.3    Jones, D.T.W.4    Pfaff, E.5    Jacob, K.6
  • 258
    • 24044492207 scopus 로고    scopus 로고
    • Pathological and molecular progression of astrocytomas in a GFAP:12 V-Ha-Ras mouse astrocytoma model
    • Retrieved from
    • Shannon P., Sabha N., Lau N., Kamnasaran D., Gutmann D.H., Guha A. Pathological and molecular progression of astrocytomas in a GFAP:12 V-Ha-Ras mouse astrocytoma model. The American Journal of Pathology 2005, 167:859-867. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1698742&tool=pmcentrez&rendertype=abstract.
    • (2005) The American Journal of Pathology , vol.167 , pp. 859-867
    • Shannon, P.1    Sabha, N.2    Lau, N.3    Kamnasaran, D.4    Gutmann, D.H.5    Guha, A.6
  • 259
    • 0030811256 scopus 로고    scopus 로고
    • Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide
    • Retrieved from
    • Shawver L.K., Schwartz D.P., Mann E., Chen H., Tsai J., Chu L., et al. Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research 1997, 3(7):1167-1177. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/9815796.
    • (1997) Clinical Cancer Research: An Official Journal of the American Association for Cancer Research , vol.3 , Issue.7 , pp. 1167-1177
    • Shawver, L.K.1    Schwartz, D.P.2    Mann, E.3    Chen, H.4    Tsai, J.5    Chu, L.6
  • 260
    • 84880303592 scopus 로고    scopus 로고
    • Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma
    • Shen J., Zheng H., Ruan J., Fang W., Li A., Tian G., et al. Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma. British Journal of Cancer 2013, 109(1):164-171. 10.1038/bjc.2013.306.
    • (2013) British Journal of Cancer , vol.109 , Issue.1 , pp. 164-171
    • Shen, J.1    Zheng, H.2    Ruan, J.3    Fang, W.4    Li, A.5    Tian, G.6
  • 261
    • 79951761651 scopus 로고    scopus 로고
    • Ezh2 expression in astrocytes induces their dedifferentiation toward neural stem cells
    • Retrieved from
    • Sher F., Boddeke E., Copray S. Ezh2 expression in astrocytes induces their dedifferentiation toward neural stem cells. Cellular Reprogramming 2011, 13:1-6. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/20979531.
    • (2011) Cellular Reprogramming , vol.13 , pp. 1-6
    • Sher, F.1    Boddeke, E.2    Copray, S.3
  • 262
    • 84863752340 scopus 로고    scopus 로고
    • Dynamic changes in Ezh2 gene occupancy underlie its involvement in neural stem cell self-renewal and differentiation towards oligodendrocytes
    • Sher F., Boddeke E., Olah M., Copray S. Dynamic changes in Ezh2 gene occupancy underlie its involvement in neural stem cell self-renewal and differentiation towards oligodendrocytes. PLoS ONE 2012, 7:e40399.
    • (2012) PLoS ONE , vol.7
    • Sher, F.1    Boddeke, E.2    Olah, M.3    Copray, S.4
  • 263
    • 56249129313 scopus 로고    scopus 로고
    • Differentiation of neural stem cells into oligodendrocytes: Involvement of the polycomb group protein Ezh2
    • Retrieved from
    • Sher F., Rössler R., Brouwer N., Balasubramaniyan V., Boddeke E., Copray S. Differentiation of neural stem cells into oligodendrocytes: Involvement of the polycomb group protein Ezh2. Stem Cells 2008, 26:2875-2883. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/18687996.
    • (2008) Stem Cells , vol.26 , pp. 2875-2883
    • Sher, F.1    Rössler, R.2    Brouwer, N.3    Balasubramaniyan, V.4    Boddeke, E.5    Copray, S.6
  • 264
    • 70350212976 scopus 로고    scopus 로고
    • STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells
    • Sherry M.M., Reeves A., Wu J.K., Cochran B.H. STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells. Stem Cells 2009, 27(10):2383-2392.
    • (2009) Stem Cells , vol.27 , Issue.10 , pp. 2383-2392
    • Sherry, M.M.1    Reeves, A.2    Wu, J.K.3    Cochran, B.H.4
  • 265
    • 3142713010 scopus 로고    scopus 로고
    • Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis
    • Shih A.H., Dai C., Hu X., Shih A.H., Dai C., Hu X., et al. Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis. Cancer Research 2004, 64:4783-4789.
    • (2004) Cancer Research , vol.64 , pp. 4783-4789
    • Shih, A.H.1    Dai, C.2    Hu, X.3    Shih, A.H.4    Dai, C.5    Hu, X.6
  • 266
    • 20444363086 scopus 로고    scopus 로고
    • Wnt signaling controls the timing of oligodendrocyte development in the spinal cord
    • Retrieved from
    • Shimizu T., Kagawa T., Wada T., Muroyama Y., Takada S., Ikenaka K. Wnt signaling controls the timing of oligodendrocyte development in the spinal cord. Developmental Biology 2005, 282:397-410. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/15950605.
    • (2005) Developmental Biology , vol.282 , pp. 397-410
    • Shimizu, T.1    Kagawa, T.2    Wada, T.3    Muroyama, Y.4    Takada, S.5    Ikenaka, K.6
  • 267
    • 58749088233 scopus 로고    scopus 로고
    • Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells
    • Shingu T., Fujiwara K., Bögler O., Akiyama Y., Moritake K., Shinojima N., et al. Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells. International Journal of Cancer 2009, 124(5):1060-1071. 10.1002/ijc.24030.
    • (2009) International Journal of Cancer , vol.124 , Issue.5 , pp. 1060-1071
    • Shingu, T.1    Fujiwara, K.2    Bögler, O.3    Akiyama, Y.4    Moritake, K.5    Shinojima, N.6
  • 269
    • 80054719845 scopus 로고    scopus 로고
    • CD140a identifies a population of highly myelinogenic, migration-competent and efficiently engrafting human oligodendrocyte progenitor cells
    • Sim F.J., McClain C.R., Schanz S.J., Protack T.L., Windrem M.S., Goldman S.A. CD140a identifies a population of highly myelinogenic, migration-competent and efficiently engrafting human oligodendrocyte progenitor cells. Nature Biotechnology 2011, 29:934-941. 10.1038/nbt.1972.
    • (2011) Nature Biotechnology , vol.29 , pp. 934-941
    • Sim, F.J.1    McClain, C.R.2    Schanz, S.J.3    Protack, T.L.4    Windrem, M.S.5    Goldman, S.A.6
  • 270
    • 70349469565 scopus 로고    scopus 로고
    • Mechanisms of polycomb gene silencing: Knowns and unknowns
    • Retrieved from
    • Simon J.A., Kingston R.E. Mechanisms of polycomb gene silencing: Knowns and unknowns. Nature Reviews Molecular Cell Biology 2009, 10:697-708. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/19738629.
    • (2009) Nature Reviews Molecular Cell Biology , vol.10 , pp. 697-708
    • Simon, J.A.1    Kingston, R.E.2
  • 272
  • 273
    • 77956178360 scopus 로고    scopus 로고
    • EMT, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer
    • Singh A., Settleman J. EMT, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer. Oncogene 2010, 29(34):4741-4751.
    • (2010) Oncogene , vol.29 , Issue.34 , pp. 4741-4751
    • Singh, A.1    Settleman, J.2
  • 274
    • 83455176258 scopus 로고    scopus 로고
    • Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma
    • Snuderl M., Fazlollahi L., Le L.P., Nitta M., Zhelyazkova B.H., Davidson C.J., et al. Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma. Cancer Cell 2011, 20(6):810-817.
    • (2011) Cancer Cell , vol.20 , Issue.6 , pp. 810-817
    • Snuderl, M.1    Fazlollahi, L.2    Le, L.P.3    Nitta, M.4    Zhelyazkova, B.H.5    Davidson, C.J.6
  • 275
    • 65349115320 scopus 로고    scopus 로고
    • SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma
    • Retrieved from
    • Son M.J., Woolard K., Nam D.-H., Lee J., Fine H.A. SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma. Cell Stem Cell 2009, 4:440-452. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/19427293.
    • (2009) Cell Stem Cell , vol.4 , pp. 440-452
    • Son, M.J.1    Woolard, K.2    Nam, D.-H.3    Lee, J.4    Fine, H.A.5
  • 276
    • 33645115547 scopus 로고    scopus 로고
    • Adding chloroquine to conventional treatment for glioblastoma multiforme: A randomized, double-blind, placebo-controlled trial
    • Sotelo J., Briceño E., López-González M.A. Adding chloroquine to conventional treatment for glioblastoma multiforme: A randomized, double-blind, placebo-controlled trial. Annals of Internal Medicine 2006, 144(5):337-343.
    • (2006) Annals of Internal Medicine , vol.144 , Issue.5 , pp. 337-343
    • Sotelo, J.1    Briceño, E.2    López-González, M.A.3
  • 277
    • 33746090935 scopus 로고    scopus 로고
    • Stem cell marker expression in the Bergmann glia population of the adult mouse brain
    • Sottile V., Li M., Scotting P.J. Stem cell marker expression in the Bergmann glia population of the adult mouse brain. Brain Research 2006, 1099(1):8-17.
    • (2006) Brain Research , vol.1099 , Issue.1 , pp. 8-17
    • Sottile, V.1    Li, M.2    Scotting, P.J.3
  • 279
    • 80655128138 scopus 로고    scopus 로고
    • Patterns of histone H3 lysine 27 monomethylation and erythroid cell type-specific gene expression
    • Steiner L.A., Schulz V.P., Maksimova Y., Wong C., Gallagher P.G. Patterns of histone H3 lysine 27 monomethylation and erythroid cell type-specific gene expression. The Journal of Biological Chemistry 2011, 286(45):39457-39465.
    • (2011) The Journal of Biological Chemistry , vol.286 , Issue.45 , pp. 39457-39465
    • Steiner, L.A.1    Schulz, V.P.2    Maksimova, Y.3    Wong, C.4    Gallagher, P.G.5
  • 280
    • 0037663384 scopus 로고    scopus 로고
    • The Sox9 transcription factor determines glial fate choice in the developing spinal cord
    • Stolt C.C., Lommes P., Sock E., Chaboissier M.-C., Schedl A., Wegner M. The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes & Development 2003, 17:1677-1689. 10.1101/gad.259003.
    • (2003) Genes & Development , vol.17 , pp. 1677-1689
    • Stolt, C.C.1    Lommes, P.2    Sock, E.3    Chaboissier, M.-C.4    Schedl, A.5    Wegner, M.6
  • 281
    • 33750447322 scopus 로고    scopus 로고
    • SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function
    • Retrieved from
    • Stolt C., Schlierf A., Lommes P., Hillgartner S., Werner T., Kosian T., et al. SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Developmental Cell 2006, 11:697-709. Retrieved from. http://discovery.ucl.ac.uk/143376/.
    • (2006) Developmental Cell , vol.11 , pp. 697-709
    • Stolt, C.1    Schlierf, A.2    Lommes, P.3    Hillgartner, S.4    Werner, T.5    Kosian, T.6
  • 282
    • 35348822482 scopus 로고    scopus 로고
    • Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies
    • Stommel J., Kimmelman A., Ying H. Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Science 2007, 287(2007). 10.1126/science.1142946.
    • (2007) Science , vol.287 , Issue.2007
    • Stommel, J.1    Kimmelman, A.2    Ying, H.3
  • 283
    • 84867606428 scopus 로고    scopus 로고
    • Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma
    • Sturm D., Witt H., Hovestadt V., Khuong-Quang D.-A., Jones D.T.W., Konermann C., et al. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 2012, 22(4):425-437.
    • (2012) Cancer Cell , vol.22 , Issue.4 , pp. 425-437
    • Sturm, D.1    Witt, H.2    Hovestadt, V.3    Khuong-Quang, D.-A.4    Jones, D.T.W.5    Konermann, C.6
  • 284
    • 80052574196 scopus 로고    scopus 로고
    • Asymmetry-defective oligodendrocyte progenitors are glioma precursors
    • Retrieved from
    • Sugiarto S., Persson A.I., Munoz E.G., Waldhuber M., Lamagna C., Andor N., et al. Asymmetry-defective oligodendrocyte progenitors are glioma precursors. Cancer Cell 2011, 20:328-340. Retrieved from. http://linkinghub.elsevier.com/retrieve/pii/S1535610811003084.
    • (2011) Cancer Cell , vol.20 , pp. 328-340
    • Sugiarto, S.1    Persson, A.I.2    Munoz, E.G.3    Waldhuber, M.4    Lamagna, C.5    Andor, N.6
  • 285
    • 23844438209 scopus 로고    scopus 로고
    • Activation of Akt and eIF4E survival pathways by rapamycin mediated mammalian target of rapamycin inhibition
    • Sun S.Y., Rosenberg L.M., Wang X., Zhou Z., Yue P., Fu H., et al. Activation of Akt and eIF4E survival pathways by rapamycin mediated mammalian target of rapamycin inhibition. Cancer Research 2005, 65:7052-7058.
    • (2005) Cancer Research , vol.65 , pp. 7052-7058
    • Sun, S.Y.1    Rosenberg, L.M.2    Wang, X.3    Zhou, Z.4    Yue, P.5    Fu, H.6
  • 286
    • 73649102464 scopus 로고    scopus 로고
    • EZH2 is essential for glioblastoma cancer stem cell maintenance
    • Retrieved from
    • Suvà M.-L., Riggi N., Janiszewska M., Radovanovic I., Provero P., Stehle J.-C., et al. EZH2 is essential for glioblastoma cancer stem cell maintenance. Cancer Research 2009, 69:9211-9218. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/19934320.
    • (2009) Cancer Research , vol.69 , pp. 9211-9218
    • Suvà, M.-L.1    Riggi, N.2    Janiszewska, M.3    Radovanovic, I.4    Provero, P.5    Stehle, J.-C.6
  • 287
    • 84857397985 scopus 로고    scopus 로고
    • Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response
    • Szerlip N.J., Pedraza A., Chakravarty D., Azim M., McGuire J., Fang Y., et al. Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response. Proceedings of the National Academy of Sciences of the United States of America 2012, 109(8):3041-3046. 10.1073/pnas.1114033109.
    • (2012) Proceedings of the National Academy of Sciences of the United States of America , vol.109 , Issue.8 , pp. 3041-3046
    • Szerlip, N.J.1    Pedraza, A.2    Chakravarty, D.3    Azim, M.4    McGuire, J.5    Fang, Y.6
  • 288
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126(4):663-676. 10.1016/j.cell.2006.07.024.
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 291
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • The Cancer Genome Atlas Research Network Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008, 455(7216):1061-1068. 10.1038/nature07385.
    • (2008) Nature , vol.455 , Issue.7216 , pp. 1061-1068
  • 292
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-Mesenchymal transitions in tumour progression
    • Thiery J.P. Epithelial-Mesenchymal transitions in tumour progression. Nature Reviews Cancer 2002, 2(6):442-454.
    • (2002) Nature Reviews Cancer , vol.2 , Issue.6 , pp. 442-454
    • Thiery, J.P.1
  • 293
    • 0035545795 scopus 로고    scopus 로고
    • Hox genes, neural crest cells and branchial arch patterning
    • Retrieved from
    • Trainor P.A., Krumlauf R. Hox genes, neural crest cells and branchial arch patterning. Current Opinion in Cell Biology 2001, 13(6):698-705. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/11698185.
    • (2001) Current Opinion in Cell Biology , vol.13 , Issue.6 , pp. 698-705
    • Trainor, P.A.1    Krumlauf, R.2
  • 295
    • 84858796263 scopus 로고    scopus 로고
    • IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
    • Turcan S., Rohle D., Goenka A., Walsh L.A., Fang F., Yilmaz E., et al. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature 2013, 483(7390):479-483.
    • (2013) Nature , vol.483 , Issue.7390 , pp. 479-483
    • Turcan, S.1    Rohle, D.2    Goenka, A.3    Walsh, L.A.4    Fang, F.5    Yilmaz, E.6
  • 296
    • 0036791177 scopus 로고    scopus 로고
    • Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt
    • Retrieved from
    • Uhrbom L., Dai C., Celestino J.C., Rosenblum M.K., Fuller G.N., Holland E.C. Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt. Cancer Research 2002, 62:5551-5558. Retrieved from. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12359767.
    • (2002) Cancer Research , vol.62 , pp. 5551-5558
    • Uhrbom, L.1    Dai, C.2    Celestino, J.C.3    Rosenblum, M.K.4    Fuller, G.N.5    Holland, E.C.6
  • 297
    • 84870325664 scopus 로고    scopus 로고
    • Identification of Hedgehog pathway responsive glioblastomas by isocitrate dehydrogenase mutation
    • Valadez J.G., Grover V.K., Carter M.D., Calcutt M.W., Abiria S.A., Lundberg C.J., et al. Identification of Hedgehog pathway responsive glioblastomas by isocitrate dehydrogenase mutation. Cancer Letters 2013, 328(2):297-306.
    • (2013) Cancer Letters , vol.328 , Issue.2 , pp. 297-306
    • Valadez, J.G.1    Grover, V.K.2    Carter, M.D.3    Calcutt, M.W.4    Abiria, S.A.5    Lundberg, C.J.6
  • 298
    • 77649122144 scopus 로고    scopus 로고
    • IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: A report of the European Organization for Research and Treatment of Cancer Brain Tumor Group
    • Van den Bent M.J., Dubbink H.J., Marie Y., Brandes A.A., Taphoorn M.J.B., Wesseling P., et al. IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: A report of the European Organization for Research and Treatment of Cancer Brain Tumor Group. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research 2010, 16(5):1597-1604. 10.1158/1078-0432.CCR-09-2902.
    • (2010) Clinical Cancer Research: An Official Journal of the American Association for Cancer Research , vol.16 , Issue.5 , pp. 1597-1604
    • Van den Bent, M.J.1    Dubbink, H.J.2    Marie, Y.3    Brandes, A.A.4    Taphoorn, M.J.B.5    Wesseling, P.6
  • 299
    • 0042425741 scopus 로고    scopus 로고
    • Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction
    • Van den Boom J., Wolter M., Kuick R., Misek D.E., Youkilis A.S., Wechsler D.S., et al. Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction. The American Journal of Pathology 2003, 163(3):1033-1043.
    • (2003) The American Journal of Pathology , vol.163 , Issue.3 , pp. 1033-1043
    • Van den Boom, J.1    Wolter, M.2    Kuick, R.3    Misek, D.E.4    Youkilis, A.S.5    Wechsler, D.S.6
  • 300
    • 84882273357 scopus 로고    scopus 로고
    • Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas
    • Venneti S., Garimella M.T., Sullivan L.M., Martinez D., Huse J.T., Heguy A., et al. Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas. Brain Pathology 2013, 23:558-564.
    • (2013) Brain Pathology , vol.23 , pp. 558-564
    • Venneti, S.1    Garimella, M.T.2    Sullivan, L.M.3    Martinez, D.4    Huse, J.T.5    Heguy, A.6
  • 301
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • Verhaak R.G.W., Hoadley K.A., Purdom E., Wang V., Qi Y., Wilkerson M.D., et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010, 17(1):98-110. 10.1016/j.ccr.2009.12.020.
    • (2010) Cancer Cell , vol.17 , Issue.1 , pp. 98-110
    • Verhaak, R.G.W.1    Hoadley, K.A.2    Purdom, E.3    Wang, V.4    Qi, Y.5    Wilkerson, M.D.6
  • 302
    • 84861760527 scopus 로고    scopus 로고
    • Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors
    • Vivanco I., Robins H.I., Rohle D., Campos C., Grommes C., Nghiemphu P.L., et al. Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors. Cancer Discovery 2012, 2(5):458-471. 10.1158/2159-8290.CD-11-0284.
    • (2012) Cancer Discovery , vol.2 , Issue.5 , pp. 458-471
    • Vivanco, I.1    Robins, H.I.2    Rohle, D.3    Campos, C.4    Grommes, C.5    Nghiemphu, P.L.6
  • 303
    • 0034085545 scopus 로고    scopus 로고
    • Evaluation of early response to SU101 target-based therapy in patients with recurrent supratentorial malignant gliomas using FDG PET and Gd-DTPA MRI
    • Retrieved from
    • Vlassenko A.G., Thiessen B., Beattie B.J., Malkin M.G., Blasberg R.G. Evaluation of early response to SU101 target-based therapy in patients with recurrent supratentorial malignant gliomas using FDG PET and Gd-DTPA MRI. Journal of Neuro-Oncology 2000, 46(3):249-259. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/10902856.
    • (2000) Journal of Neuro-Oncology , vol.46 , Issue.3 , pp. 249-259
    • Vlassenko, A.G.1    Thiessen, B.2    Beattie, B.J.3    Malkin, M.G.4    Blasberg, R.G.5
  • 304
    • 82955182157 scopus 로고    scopus 로고
    • Cediranib enhances control of wild type EGFR and EGFRvIII-expressing gliomas through potentiating temozolomide, but not through radiosensitization: Implications for the clinic
    • Wachsberger P.R., Lawrence R.Y., Liu Y., Xia X., Andersen B., Dicker A.P. Cediranib enhances control of wild type EGFR and EGFRvIII-expressing gliomas through potentiating temozolomide, but not through radiosensitization: Implications for the clinic. Journal of Neuro-Oncology 2011, 105(2):181-190. 10.1007/s11060-011-0580-y.
    • (2011) Journal of Neuro-Oncology , vol.105 , Issue.2 , pp. 181-190
    • Wachsberger, P.R.1    Lawrence, R.Y.2    Liu, Y.3    Xia, X.4    Andersen, B.5    Dicker, A.P.6
  • 305
    • 78650098659 scopus 로고    scopus 로고
    • Glioblastoma stem-like cells give rise to tumour endothelium
    • Wang R., Chadalavada K., Wilshire J., Kowalik U., Hovinga K.E., Geber A., et al. Glioblastoma stem-like cells give rise to tumour endothelium. Nature 2010, 468:829-833. 10.1038/nature09624.
    • (2010) Nature , vol.468 , pp. 829-833
    • Wang, R.1    Chadalavada, K.2    Wilshire, J.3    Kowalik, U.4    Hovinga, K.E.5    Geber, A.6
  • 306
    • 33748058820 scopus 로고    scopus 로고
    • Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells
    • Wang M.Y., Lu K.V., Zhu S., Dia E.Q., Vivanco I., Shackleford G.M., et al. Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells. Cancer Research 2006, 66(16):7864-7869. 10.1158/0008-5472.CAN-04-4392.
    • (2006) Cancer Research , vol.66 , Issue.16 , pp. 7864-7869
    • Wang, M.Y.1    Lu, K.V.2    Zhu, S.3    Dia, E.Q.4    Vivanco, I.5    Shackleford, G.M.6
  • 307
    • 84880398240 scopus 로고    scopus 로고
    • CD133/CD140a-based isolation of distinct human multipotent neural progenitor cells and oligodendrocyte progenitor cells
    • Wang J., O'Bara M.A., Pol S.U., Sim F.J. CD133/CD140a-based isolation of distinct human multipotent neural progenitor cells and oligodendrocyte progenitor cells. Stem Cells and Development 2013, 22(15):2121-2131. 10.1089/scd.2013.0003.
    • (2013) Stem Cells and Development , vol.22 , Issue.15 , pp. 2121-2131
    • Wang, J.1    O'Bara, M.A.2    Pol, S.U.3    Sim, F.J.4
  • 308
    • 0032126751 scopus 로고    scopus 로고
    • Notch receptor activation inhibits oligodendrocyte differentiation
    • Retrieved from
    • Wang S., Sdrulla A.D., diSibio G., Bush G., Nofziger D., Hicks C., et al. Notch receptor activation inhibits oligodendrocyte differentiation. Neuron 1998, 21:63-75. Retrieved from. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9697852.
    • (1998) Neuron , vol.21 , pp. 63-75
    • Wang, S.1    Sdrulla, A.D.2    diSibio, G.3    Bush, G.4    Nofziger, D.5    Hicks, C.6
  • 309
    • 84882737154 scopus 로고    scopus 로고
    • Combination of mTOR and EGFR kinase inhibitors blocks mTORC1 and mTORC2 kinase activity and suppresses the progression of colorectal carcinoma
    • Wang Q., Wei F., Li C., Lv G., Wang G., Liu T., et al. Combination of mTOR and EGFR kinase inhibitors blocks mTORC1 and mTORC2 kinase activity and suppresses the progression of colorectal carcinoma. PloS One 2013, 8(8):e73175. 10.1371/journal.pone.0073175.
    • (2013) PloS One , vol.8 , Issue.8
    • Wang, Q.1    Wei, F.2    Li, C.3    Lv, G.4    Wang, G.5    Liu, T.6
  • 310
    • 65649142176 scopus 로고    scopus 로고
    • Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model
    • Retrieved from
    • Wang Y., Yang J., Zheng H., Tomasek G.J., Zhang P., McKeever P.E., et al. Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model. Cancer Cell 2009, 15:514-526. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/19477430.
    • (2009) Cancer Cell , vol.15 , pp. 514-526
    • Wang, Y.1    Yang, J.2    Zheng, H.3    Tomasek, G.J.4    Zhang, P.5    McKeever, P.E.6
  • 311
    • 79960905269 scopus 로고    scopus 로고
    • Hepatocyte growth factor acts as a mitogen and chemoattractant for postnatal subventricular zone-olfactory bulb neurogenesis
    • Retrieved from
    • Wang T.-W., Zhang H., Gyetko M.R., Parent J.M. Hepatocyte growth factor acts as a mitogen and chemoattractant for postnatal subventricular zone-olfactory bulb neurogenesis. Molecular and Cellular Neurosciences 2011, 48:38-50. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3160177&tool=pmcentrez&rendertype=abstract.
    • (2011) Molecular and Cellular Neurosciences , vol.48 , pp. 38-50
    • Wang, T.-W.1    Zhang, H.2    Gyetko, M.R.3    Parent, J.M.4
  • 312
    • 65349150503 scopus 로고    scopus 로고
    • IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas
    • Watanabe T., Nobusawa S., Kleihues P., Ohgaki H. IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas. The American Journal of Pathology 2009, 174(4):1149-1153.
    • (2009) The American Journal of Pathology , vol.174 , Issue.4 , pp. 1149-1153
    • Watanabe, T.1    Nobusawa, S.2    Kleihues, P.3    Ohgaki, H.4
  • 313
    • 84866343528 scopus 로고    scopus 로고
    • CT322, a VEGFR-2 antagonist, demonstrates anti-glioma efficacy in orthotopic brain tumor model as a single agent or in combination with temozolomide and radiation therapy
    • Waters J.D., Sanchez C., Sahin A., Futalan D., Gonda D.D., Scheer J.K., et al. CT322, a VEGFR-2 antagonist, demonstrates anti-glioma efficacy in orthotopic brain tumor model as a single agent or in combination with temozolomide and radiation therapy. Journal of Neuro-Oncology 2012, 110(1):37-48. 10.1007/s11060-012-0948-7.
    • (2012) Journal of Neuro-Oncology , vol.110 , Issue.1 , pp. 37-48
    • Waters, J.D.1    Sanchez, C.2    Sahin, A.3    Futalan, D.4    Gonda, D.D.5    Scheer, J.K.6
  • 314
    • 33747885901 scopus 로고    scopus 로고
    • High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model
    • Retrieved from
    • Wei Q., Clarke L., Scheidenhelm D.K., Qian B., Tong A., Sabha N., et al. High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model. Cancer Research 2006, 66:7429-7437. Retrieved from. http://www.ncbi.nlm.nih.gov/pubmed/16885338.
    • (2006) Cancer Research , vol.66 , pp. 7429-7437
    • Wei, Q.1    Clarke, L.2    Scheidenhelm, D.K.3    Qian, B.4    Tong, A.5    Sabha, N.6
  • 315
    • 0037382205 scopus 로고    scopus 로고
    • Genetic determinants of malignancy in a mouse model for oligodendroglioma
    • Weiss W.A., Burns M.J., Hackett C., Aldape K., Hill J.R., Kuriyama H., et al. Genetic determinants of malignancy in a mouse model for oligodendroglioma. Cancer Research 2003, 63:1589-1595. http://www.ncbi.nlm.nih.gov/pubmed/12670909.
    • (2003) Cancer Research , vol.63 , pp. 1589-1595
    • Weiss, W.A.1    Burns, M.J.2    Hackett, C.3    Aldape, K.4    Hill, J.R.5    Kuriyama, H.6
  • 317
    • 84884711305 scopus 로고    scopus 로고
    • Proneural genes in neocortical development
    • Wilkinson G., Dennis D., Schuurmans C. Proneural genes in neocortical development. Neuroscience 2013, 253C:256-273.
    • (2013) Neuroscience , vol.253 C , pp. 256-273
    • Wilkinson, G.1    Dennis, D.2    Schuurmans, C.3
  • 318
    • 84862777410 scopus 로고    scopus 로고
    • Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
    • Wu G., Broniscer A., McEachron T.A., Lu C., Paugh B.S., Becksfort J., et al. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nature Genetics 2012, 44(3):251-253.
    • (2012) Nature Genetics , vol.44 , Issue.3 , pp. 251-253
    • Wu, G.1    Broniscer, A.2    McEachron, T.A.3    Lu, C.4    Paugh, B.S.5    Becksfort, J.6
  • 320
    • 78651463452 scopus 로고    scopus 로고
    • Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases
    • Xu W., Yang H., Liu Y., Yang Y., Wang P., Kim S.H., et al. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell 2011, 219(1):17-30.
    • (2011) Cancer Cell , vol.219 , Issue.1 , pp. 17-30
    • Xu, W.1    Yang, H.2    Liu, Y.3    Yang, Y.4    Wang, P.5    Kim, S.H.6
  • 321
    • 83355166909 scopus 로고    scopus 로고
    • Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth
    • Yakes F.M., Chen J., Tan J., Yamaguchi K., Shi Y., Yu P., et al. Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth. Molecular Cancer Therapeutics 2011, 10(12):2298-2308. 10.1158/1535-7163.MCT-11-0264.
    • (2011) Molecular Cancer Therapeutics , vol.10 , Issue.12 , pp. 2298-2308
    • Yakes, F.M.1    Chen, J.2    Tan, J.3    Yamaguchi, K.4    Shi, Y.5    Yu, P.6
  • 323
    • 77953005998 scopus 로고    scopus 로고
    • Targeting the dimerization of epidermal growth factor receptors with small-molecule inhibitors
    • Yang R.Y.C., Yang K.S., Pike L.J., Marshall G.R. Targeting the dimerization of epidermal growth factor receptors with small-molecule inhibitors. Chemical Biology & Drug Design 2010, 76(1):1-9. 10.1111/j.1747-0285.2010.00986.x.
    • (2010) Chemical Biology & Drug Design , vol.76 , Issue.1 , pp. 1-9
    • Yang, R.Y.C.1    Yang, K.S.2    Pike, L.J.3    Marshall, G.R.4
  • 324
    • 82755194965 scopus 로고    scopus 로고
    • Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers
    • Yip S., Butterfield Y.S., Morozova O., Chittaranjan S., Blough M.D., An J., et al. Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers. The Journal of Pathology 2011, 226(1):7-16.
    • (2011) The Journal of Pathology , vol.226 , Issue.1 , pp. 7-16
    • Yip, S.1    Butterfield, Y.S.2    Morozova, O.3    Chittaranjan, S.4    Blough, M.D.5    An, J.6
  • 325
    • 0037075806 scopus 로고    scopus 로고
    • A non-transgenic mouse model for B-cell lymphoma: In vivo infection of p53-null bone marrow progenitors by a Myc retrovirus is sufficient for tumorigenesis
    • Yu D., Thomas-Tikhonenko A. A non-transgenic mouse model for B-cell lymphoma: In vivo infection of p53-null bone marrow progenitors by a Myc retrovirus is sufficient for tumorigenesis. Oncogene 2002, 21(12):1922-1927.
    • (2002) Oncogene , vol.21 , Issue.12 , pp. 1922-1927
    • Yu, D.1    Thomas-Tikhonenko, A.2
  • 327
    • 67649412006 scopus 로고    scopus 로고
    • TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition
    • Zhang H., Liu C.-Y., Zha Z.-Y., Zhao B., Yao J., Zhao S., et al. TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. The Journal of Biological Chemistry 2009, 284(20):13355-13362.
    • (2009) The Journal of Biological Chemistry , vol.284 , Issue.20 , pp. 13355-13362
    • Zhang, H.1    Liu, C.-Y.2    Zha, Z.-Y.3    Zhao, B.4    Yao, J.5    Zhao, S.6
  • 328
    • 84878723078 scopus 로고    scopus 로고
    • Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas
    • Zhang J., Wu G., Miller C.P., Tatevossian R.G., Dalton J.D., Tang B., et al. Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nature Genetics 2013, 45(6):602-612.
    • (2013) Nature Genetics , vol.45 , Issue.6 , pp. 602-612
    • Zhang, J.1    Wu, G.2    Miller, C.P.3    Tatevossian, R.G.4    Dalton, J.D.5    Tang, B.6
  • 329
    • 77951837150 scopus 로고    scopus 로고
    • The Hippo-YAP pathway in organ size control and tumorigenesis: An updated version
    • Zhao B., Li L., Lei Q., Guan K.-L. The Hippo-YAP pathway in organ size control and tumorigenesis: An updated version. Genes & Development 2010, 24(9):862-874.
    • (2010) Genes & Development , vol.24 , Issue.9 , pp. 862-874
    • Zhao, B.1    Li, L.2    Lei, Q.3    Guan, K.-L.4
  • 330
    • 64849098267 scopus 로고    scopus 로고
    • Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha
    • Zhao S., Lin Y., Xu W., Jiang W., Zha Z., Wang P., et al. Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. Science 2009, 324(5924):261-265.
    • (2009) Science , vol.324 , Issue.5924 , pp. 261-265
    • Zhao, S.1    Lin, Y.2    Xu, W.3    Jiang, W.4    Zha, Z.5    Wang, P.6
  • 332
    • 23644443053 scopus 로고    scopus 로고
    • Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma
    • Retrieved from
    • Zhu Y., Guignard F., Zhao D., Liu L., Burns D.K., Mason R.P., et al. Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma. Cancer Cell 2005, 8:119-130. Retrieved from. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3024718&tool=pmcentrez&rendertype=abstract.
    • (2005) Cancer Cell , vol.8 , pp. 119-130
    • Zhu, Y.1    Guignard, F.2    Zhao, D.3    Liu, L.4    Burns, D.K.5    Mason, R.P.6
  • 333
    • 84877875172 scopus 로고    scopus 로고
    • Polydendrocytes in development and myelin repair
    • Zuo H., Nishiyama A. Polydendrocytes in development and myelin repair. Neuroscience Bulletin 2013, 1-12. 10.1007/s12264-013-1320-4.
    • (2013) Neuroscience Bulletin
    • Zuo, H.1    Nishiyama, A.2


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