Biomarkers classification and therapeutic decision-making for malignant gliomas

Current Treatment Options in Oncology

Volumn 13, Issue 4, 2012, Pages 417-436

  Olar, Adriana ^a   Aldape, Kenneth D ^b  

^a HOUSTON METHODIST HOSPITAL   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

1p19q; BRAF; BRAF KIAA1549; BRAFV600E; CIC; Diffuse glioma; EGFR; EGFRvIII; G CIMP; IDH; Ki 67; Mesenchymal; MGMT; MIB 1; PHH3; Predictive markers; Prognosis; Proneural; TP53; Treatment

Indexed keywords

B RAF KINASE; BIOLOGICAL MARKER; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR VIII; GEFITINIB; GLUTAMIC ACID; HISTONE H3; HYBRID PROTEIN; ISOCITRATE DEHYDROGENASE 1; ISOCITRATE DEHYDROGENASE 2; KI 67 ANTIGEN; LOMUSTINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROCARBAZINE; PROTEIN P53; TEMOZOLOMIDE; UNCLASSIFIED DRUG; VALINE; VEMURAFENIB; VINCRISTINE;

ANAPLASTIC OLIGODENDROGLIAL TUMOR; ARTICLE; BRAIN TUMOR; CANCER ADJUVANT THERAPY; CANCER CLASSIFICATION; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; CARCINOGENESIS; CHROMOSOME 19Q; CHROMOSOME 1P; CHROMOSOME TRANSLOCATION; CIC GENE; CLINICAL DECISION MAKING; CPG ISLAND; DNA METHYLATION; DRUG METABOLISM; DRUG PENETRATION; DRUG POTENCY; GENE; GENE DELETION; GENE EXPRESSION; GENOMIC INSTABILITY; GLIOBLASTOMA; GLIOMA; HETEROZYGOSITY LOSS; HUMAN; INCIDENCE; LUNG CANCER; OLIGODENDROGLIOMA; PHENOTYPE; PILOCYTIC ASTROCYTOMA; PLEOMORPHIC XANTHOASTROCYTOMA; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTO ONCOGENE BRAF; TP53 GENE; TREATMENT RESPONSE;

BRAIN NEOPLASMS; CPG ISLANDS; DECISION MAKING; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; ISOCITRATE DEHYDROGENASE; MUTATION; PROGNOSIS; PROTO-ONCOGENE PROTEINS B-RAF; RECEPTOR, EPIDERMAL GROWTH FACTOR; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84870804965     PISSN: 15272729     EISSN: 15346277     Source Type: Journal    
DOI: 10.1007/s11864-012-0210-8     Document Type: Article

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