CSF-1R inhibition alters macrophage polarization and blocks glioma progression

Nature Medicine

Volumn 19, Issue 10, 2013, Pages 1264-1272

  Pyonteck, Stephanie M ^a   Akkari, Leila ^a   Schuhmacher, Alberto J ^a   Bowman, Robert L ^a   Sevenich, Lisa ^a   Quail, Daniela F ^a   Olson, Oakley C ^a   Quick, Marsha L ^a   Huse, Jason T ^a   Teijeiro, Virginia ^a   Setty, Manu ^a   Leslie, Christina S ^a   Oei, Yoko ^b   Pedraza, Alicia ^a   Zhang, Jianan ^a   Brennan, Cameron W ^a   Sutton, James C ^b   Holland, Eric C ^a   Daniel, Dylan ^b   Joyce, Johanna A ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BLZ 945; COLONY STIMULATING FACTOR 1 RECEPTOR; COLONY STIMULATING FACTOR RECEPTOR; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER SURVIVAL; CELL POLARITY; CELL SURVIVAL; CONTROLLED STUDY; DRUG SCREENING; DRUG TARGETING; DRUG TOLERABILITY; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; LONG TERM SURVIVAL; MACROPHAGE; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL TIME; TARGET CELL; TUMOR XENOGRAFT; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN TUMOR; CYTOLOGY; DISEASE COURSE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

MUS;

ANIMALS; BRAIN NEOPLASMS; DISEASE PROGRESSION; GLIOBLASTOMA; MACROPHAGES; MICE; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; SIGNAL TRANSDUCTION;

EID: 84887481716     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3337     Document Type: Article

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