Proneural genes in neocortical development

Neuroscience

Volumn 253, Issue , 2013, Pages 256-273

  Wilkinson, G ^a   Dennis, D ^a   Schuurmans, C ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Astrocyte and oligodendrocyte cell fates; Basic helix loop helix transcription factors; GABAergic and glutamatergic neuronal fates; Neocortex; Neurog1, Neurog2, Ascl1; Proneural genes

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3; HAIRY AND ENHANCER OF SPLIT 1 PROTEIN; NEUROGENIN 1; NEUROGENIN 2; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR MASH1; TRANSCRIPTION FACTOR PU 1; UNCLASSIFIED DRUG;

ACHAETE SCUTE LIKE 1 GENE; BRAIN DEVELOPMENT; BRAIN MATURATION; BRAIN NERVE CELL; CELL CYCLE PHASE; CELL DIFFERENTIATION; CELL FATE; CELL LINEAGE; CELL MIGRATION; GAIN OF FUNCTION MUTATION; GENE CONTROL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INTERACTION; GENE SWITCHING; GENETIC SELECTION; GLIA CELL; HUMAN; INTRACELLULAR SIGNALING; LOSS OF FUNCTION MUTATION; MOLECULAR DYNAMICS; NEOCORTEX; NEUROG 2 GENE; NEUROGENIN 1 GENE; NONHUMAN; OLIGODENDROCYTE PRECURSOR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STABILITY; REVIEW; TELENCEPHALON; UPREGULATION; WNT SIGNALING PATHWAY;

ACHAETE SCUTE-LIKE 1; ACHAETE-SCUTE COMPLEX; AS-C; ASCL1; ASTROCYTE AND OLIGODENDROCYTE CELL FATES; BAF; BASIC-HELIX-LOOP-HELIX; BASIC-HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BHLH; BRAHMA-ASSOCIATED FACTORS; CAUDAL GANGLIONIC EMINENCES; CGE; GABA(+); GABAERGIC; GABAERGIC AND GLUTAMATERGIC NEURONAL FATES; GLU(+); GLUTAMATERGIC; GLYCOGEN SYNTHASE KINASE 3; GSK3; HAIRY AND ENHANCER OF SPLIT 1; HES1; HIGH MOBILITY GROUP A; HMGA; LATERAL GANGLIONIC EMINENCES; LGE; MEDIAL GANGLIONIC EMINENCES; MGE; NEOCORTEX; NEUROG; NEUROG1, NEUROG2, ASCL1; NEUROGENIN; NICD; NOTCH INTRACELLULAR DOMAIN; OLIGODENDROCYTE PRECURSOR CELLS; OPCS; PCG; PCG REPRESSIVE COMPLEX; POLYCOMB; PRC; PRONEURAL GENES; RADIAL GLIAL CELLS; RGCS; SERINE-PROLINE; SIGNAL TRANSDUCERS AND ACTIVATORS OF TRANSCRIPTION; SP; STAT; SUBVENTRICULAR ZONE; SVZ; VENTRICULAR ZONE; VZ;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; NEOCORTEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; STEM CELLS;

EID: 84884711305     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.08.029     Document Type: Review

References (201)

1. Abematsu M., Kagawa T., Fukuda S., Inoue T., Takebayashi H., Komiya S., Taga T. Basic fibroblast growth factor endows dorsal telencephalic neural progenitors with the ability to differentiate into oligodendrocytes but not gamma-aminobutyric acidergic neurons. J Neurosci Res 2006, 83:731-743.
2. Akazawa C., Sasai Y., Nakanishi S., Kageyama R. Molecular characterization of a rat negative regulator with a basic helix-loop-helix structure predominantly expressed in the developing nervous system. J Biol Chem 1992, 267:21879-21885.
3. Ali F., Hindley C., McDowell G., Deibler R., Jones A., Kirschner M., Guillemot F., Philpott A. Cell cycle-regulated multi-site phosphorylation of neurogenin 2 coordinates cell cycling with differentiation during neurogenesis. Development 2011, 138:4267-4277.
4. Alifragis P., Poortinga G., Parkhurst S.M., Delidakis C. A network of interacting transcriptional regulators involved in Drosophila neural fate specification revealed by the yeast two-hybrid system. Proc Natl Acad Sci U S A 1997, 94:13099-13104.
5. Anderson S.A., Eisenstat D.D., Shi L., Rubenstein J.L. Interneuron migration from basal forebrain to neocortex: dependence on Dlx genes. Science 1997, 278:474-476.
6. Anderson S.A., Kaznowski C.E., Horn C., Rubenstein J.L., McConnell S.K. Distinct origins of neocortical projection neurons and interneurons in vivo. Cereb Cortex 2002, 12:702-709.
7. Anderson S.A., Marin O., Horn C., Jennings K., Rubenstein J.L. Distinct cortical migrations from the medial and lateral ganglionic eminences. Development 2001, 128:353-363.
8. Anderson S.A., Qiu M., Bulfone A., Eisenstat D.D., Meneses J., Pedersen R., Rubenstein J.L. Mutations of the homeobox genes Dlx-1 and Dlx-2 disrupt the striatal subventricular zone and differentiation of late born striatal neurons. Neuron 1997, 19:27-37.
9. Arber S., Ladle D.R., Lin J.H., Frank E., Jessell T.M. ETS gene Er81 controls the formation of functional connections between group Ia sensory afferents and motor neurons. Cell 2000, 101:485-498.
10. Aulehla A., Wehrle C., Brand-Saberi B., Kemler R., Gossler A., Kanzler B., Herrmann B.G. Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Dev Cell 2003, 4:395-406.
11. Azevedo F.A., Carvalho L.R., Grinberg L.T., Farfel J.M., Ferretti R.E., Leite R.E., Jacob Filho W., Lent R., Herculano-Houzel S. Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain. J Comp Neurol 2009, 513:532-541.
12. Aziz A., Liu Q.C., Dilworth F.J. Regulating a master regulator: establishing tissue-specific gene expression in skeletal muscle. Epigenetics 2010, 5:691-695.
13. Backman M., Machon O., Mygland L., van den Bout C.J., Zhong W., Taketo M.M., Krauss S. Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon. Dev Biol 2005, 279:155-168.
14. Bai G., Sheng N., Xie Z., Bian W., Yokota Y., Benezra R., Kageyama R., Guillemot F., Jing N. Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1. Dev Cell 2007, 13:283-297.
15. Barnes A.P., Polleux F. Establishment of axon-dendrite polarity in developing neurons. Annu Rev Neurosci 2009, 32:347-381.
16. Basak O., Taylor V. Identification of self-replicating multipotent progenitors in the embryonic nervous system by high Notch activity and Hes5 expression. Eur J Neurosci 2007, 25:1006-1022.
17. Battiste J., Helms A.W., Kim E.J., Savage T.K., Lagace D.C., Mandyam C.D., Eisch A.J., Miyoshi G., Johnson J.E. Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord. Development 2007, 134:285-293.
18. Berninger B., Guillemot F., Gotz M. Directing neurotransmitter identity of neurones derived from expanded adult neural stem cells. Eur J Neurosci 2007, 25:2581-2590.
19. Bertrand N., Castro D.S., Guillemot F. Proneural genes and the specification of neural cell types. Nat Rev Neurosci 2002, 3:517-530.
20. Bluske K.K., Vue T.Y., Kawakami Y., Taketo M.M., Yoshikawa K., Johnson J.E., Nakagawa Y. Beta-Catenin signaling specifies progenitor cell identity in parallel with Shh signaling in the developing mammalian thalamus. Development 2012, 139:2692-2702.
21. Britz O., Mattar P., Nguyen L., Langevin L.M., Zimmer C., Alam S., Guillemot F., Schuurmans C. A role for proneural genes in the maturation of cortical progenitor cells. Cereb Cortex 2006, 16(Suppl. 1):i138-151.
22. Brunetti-Pierri N., Berg J.S., Scaglia F., Belmont J., Bacino C.A., Sahoo T., Lalani S.R., Graham B., Lee B., Shinawi M., Shen J., Kang S.H., Pursley A., Lotze T., Kennedy G., Lansky-Shafer S., Weaver C., Roeder E.R., Grebe T.A., Arnold G.L., Hutchison T., Reimschisel T., Amato S., Geragthy M.T., Innis J.W., Obersztyn E., Nowakowska B., Rosengren S.S., Bader P.I., Grange D.K., Naqvi S., Garnica A.D., Bernes S.M., Fong C.T., Summers A., Walters W.D., Lupski J.R., Stankiewicz P., Cheung S.W., Patel A. Recurrent reciprocal 1q21.1 deletions and duplications associated with microcephaly or macrocephaly and developmental and behavioral abnormalities. Nat Genet 2008, 40:1466-1471.
23. Butt S.J., Fuccillo M., Nery S., Noctor S., Kriegstein A., Corbin J.G., Fishell G. The temporal and spatial origins of cortical interneurons predict their physiological subtype. Neuron 2005, 48:591-604.
24. Cabrera C.V., Alonso M.C. Transcriptional activation by heterodimers of the achaete-scute and daughterless gene products of Drosophila. EMBO J 1991, 10:2965-2973.
25. Cai L., Morrow E.M., Cepko C.L. Misexpression of basic helix-loop-helix genes in the murine cerebral cortex affects cell fate choices and neuronal survival. Development 2000, 127:3021-3030.
26. Caiazzo M., Dell'Anno M.T., Dvoretskova E., Lazarevic D., Taverna S., Leo D., Sotnikova T.D., Menegon A., Roncaglia P., Colciago G., Russo G., Carninci P., Pezzoli G., Gainetdinov R.R., Gustincich S., Dityatev A., Broccoli V. Direct generation of functional dopaminergic neurons from mouse and human fibroblasts. Nature 2011, 476:224-227.
27. Calegari F., Haubensak W., Haffner C., Huttner W.B. Selective lengthening of the cell cycle in the neurogenic subpopulation of neural progenitor cells during mouse brain development. J Neurosci 2005, 25:6533-6538.
28. Calegari F., Huttner W.B. An inhibition of cyclin-dependent kinases that lengthens, but does not arrest, neuroepithelial cell cycle induces premature neurogenesis. J Cell Sci 2003, 116:4947-4955.
29. Casarosa S., Fode C., Guillemot F. Mash1 regulates neurogenesis in the ventral telencephalon. Development 1999, 126:525-534.
30. Castro D.S., Martynoga B., Parras C., Ramesh V., Pacary E., Johnston C., Drechsel D., Lebel-Potter M., Garcia L.G., Hunt C., Dolle D., Bithell A., Ettwiller L., Buckley N., Guillemot F. A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets. Genes Dev 2011, 25:930-945.
31. Castro D.S., Skowronska-Krawczyk D., Armant O., Donaldson I.J., Parras C., Hunt C., Critchley J.A., Nguyen L., Gossler A., Gottgens B., Matter J.M., Guillemot F. Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif. Dev Cell 2006, 11:831-844.
32. Caviness V.S. Neocortical histogenesis in normal and reeler mice: a developmental study based upon [3H]thymidine autoradiography. Brain Res 1982, 256:293-302.
33. Caviness V.S., Takahashi T., Nowakowski R.S. Numbers, time and neocortical neuronogenesis: a general developmental and evolutionary model. Trends Neurosci 1995, 18:379-383.
34. Chandran S., Kato H., Gerreli D., Compston A., Svendsen C.N., Allen N.D. FGF-dependent generation of oligodendrocytes by a hedgehog-independent pathway. Development 2003, 130:6599-6609.
35. Chen B., Schaevitz L.R., McConnell S.K. Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex. Proc Natl Acad Sci U S A 2005, 102:17184-17189.
36. Chi T.H., Wan M., Lee P.P., Akashi K., Metzger D., Chambon P., Wilson C.B., Crabtree G.R. Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development. Immunity 2003, 19:169-182.
37. Chickarmane V., Enver T., Peterson C. Computational modeling of the hematopoietic erythroid-myeloid switch reveals insights into cooperativity, priming, and irreversibility. PLoS Comput Biol 2009, 5:e1000268.
38. Crespi B., Stead P., Elliot M. Evolution in health and medicine Sackler colloquium: comparative genomics of autism and schizophrenia. Proc Natl Acad Sci U S A 2009, 107(Suppl. 1):1736-1741.
39. Cross M.A., Enver T. The lineage commitment of haemopoietic progenitor cells. Curr Opin Genet Dev 1997, 7:609-613.
40. Dang L., Yoon K., Wang M., Gaiano N. Notch3 signaling promotes radial glial/progenitor character in the mammalian telencephalon. Dev Neurosci 2006, 28:58-69.
41. Dehay C., Kennedy H. Cell-cycle control and cortical development. Nat Rev Neurosci 2007, 8:438-450.
42. Dillon N. Factor mediated gene priming in pluripotent stem cells sets the stage for lineage specification. Bioessays 2012.
43. Dixit R., Zimmer C., Waclaw R.R., Mattar P., Shaker T., Kovach C., Logan C., Campbell K., Guillemot F., Schuurmans C. Ascl1 participates in Cajal-Retzius cell development in the neocortex. Cereb Cortex 2011, 21:2599-2611.
44. Englund C., Fink A., Lau C., Pham D., Daza R.A., Bulfone A., Kowalczyk T., Hevner R.F. Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex. J Neurosci 2005, 25:247-251.
45. Enver T., Pera M., Peterson C., Andrews P.W. Stem cell states, fates, and the rules of attraction. Cell Stem Cell 2009, 4:387-397.
46. Fangusaro J. Pediatric high grade glioma: a review and update on tumor clinical characteristics and biology. Front Oncol 2012, 2:105.
47. Farah M.H., Olson J.M., Sucic H.B., Hume R.I., Tapscott S.J., Turner D.L. Generation of neurons by transient expression of neural bHLH proteins in mammalian cells. Development 2000, 127:693-702.
48. Feng J., Fouse S., Fan G. Epigenetic regulation of neural gene expression and neuronal function. Pediatr Res 2007, 61:58R-63R.
49. Fertuzinhos S., Krsnik Z., Kawasawa Y.I., Rasin M.R., Kwan K.Y., Chen J.G., Judas M., Hayashi M., Sestan N. Selective depletion of molecularly defined cortical interneurons in human holoprosencephaly with severe striatal hypoplasia. Cereb Cortex 2009, 19:2196-2207.
50. Fode C., Ma Q., Casarosa S., Ang S.L., Anderson D.J., Guillemot F. A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons. Genes Dev 2000, 14:67-80.
51. Forcales S.V., Puri P.L. Signaling to the chromatin during skeletal myogenesis: novel targets for pharmacological modulation of gene expression. Semin Cell Dev Biol 2005, 16:596-611.
52. Gabay L., Lowell S., Rubin L.L., Anderson D.J. Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro. Neuron 2003, 40:485-499.
53. Gaiano N., Nye J.S., Fishell G. Radial glial identity is promoted by Notch1 signaling in the murine forebrain. Neuron 2000, 26:395-404.
54. Galceran J., Sustmann C., Hsu S.C., Folberth S., Grosschedl R. LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis. Genes Dev 2004, 18:2718-2723.
55. Garcia-Bellido A. Genetic analysis of the achaete-scute system of Drosophila melanogaster. Genetics 1979, 91:491-520.
56. Ge W., He F., Kim K.J., Blanchi B., Coskun V., Nguyen L., Wu X., Zhao J., Heng J.I., Martinowich K., Tao J., Wu H., Castro D., Sobeih M.M., Corfas G., Gleeson J.G., Greenberg M.E., Guillemot F., Sun Y.E. Coupling of cell migration with neurogenesis by proneural bHLH factors. Proc Natl Acad Sci U S A 2006, 103:1319-1324.
57. Geoffroy C.G., Critchley J.A., Castro D.S., Ramelli S., Barraclough C., Descombes P., Guillemot F., Raineteau O. Engineering of dominant active basic helix-loop-helix proteins that are resistant to negative regulation by postnatal central nervous system antineurogenic cues. Stem Cells 2009, 27:847-856.
58. Giresi P.G., Lieb J.D. Isolation of active regulatory elements from eukaryotic chromatin using FAIRE (Formaldehyde Assisted Isolation of Regulatory Elements). Methods 2009, 48:233-239.
59. Gohlke J.M., Armant O., Parham F.M., Smith M.V., Zimmer C., Castro D.S., Nguyen L., Parker J.S., Gradwohl G., Portier C.J., Guillemot F. Characterization of the proneural gene regulatory network during mouse telencephalon development. BMC Biol 2008, 6:15.
60. Golbabapour S., Majid N.A., Hassandarvish P., Hajrezaie M., Abdulla M.A., Hadi A.H. Gene silencing and polycomb group proteins: an overview of their structure, mechanisms and phylogenetics. OMICS 2013, 17:283-296.
61. Gonzalez-Quevedo R., Lee Y., Poss K.D., Wilkinson D.G. Neuronal regulation of the spatial patterning of neurogenesis. Dev Cell 2010, 18:136-147.
62. Gotz M., Huttner W.B. The cell biology of neurogenesis. Nat Rev Mol Cell Biol 2005, 6:777-788.
63. Gradwohl G., Fode C., Guillemot F. Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors. Dev Biol 1996, 180:227-241.
64. Guichet P.O., Bieche I., Teigell M., Serguera C., Rothhut B., Rigau V., Scamps F., Ripoll C., Vacher S., Taviaux S., Chevassus H., Duffau H., Mallet J., Susini A., Joubert D., Bauchet L., Hugnot J.P. Cell death and neuronal differentiation of glioblastoma stem-like cells induced by neurogenic transcription factors. Glia 2013, 61:225-239.
65. Gunhaga L., Marklund M., Sjodal M., Hsieh J.C., Jessell T.M., Edlund T. Specification of dorsal telencephalic character by sequential Wnt and FGF signaling. Nat Neurosci 2003, 6:701-707.
66. Hack M.A., Sugimori M., Lundberg C., Nakafuku M., Gotz M. Regionalization and fate specification in neurospheres: the role of Olig2 and Pax6. Mol Cell Neurosci 2004, 25:664-678.
67. Hand R., Bortone D., Mattar P., Nguyen L., Heng J.I., Guerrier S., Boutt E., Peters E., Barnes A.P., Parras C., Schuurmans C., Guillemot F., Polleux F. Phosphorylation of Neurogenin2 specifies the migration properties and the dendritic morphology of pyramidal neurons in the neocortex. Neuron 2005, 48:45-62.
68. Hand R., Polleux F. Neurogenin2 regulates the initial axon guidance of cortical pyramidal neurons projecting medially to the corpus callosum. Neural Dev 2011, 6:30.
69. Hasegawa H., Ashigaki S., Takamatsu M., Suzuki-Migishima R., Ohbayashi N., Itoh N., Takada S., Tanabe Y. Laminar patterning in the developing neocortex by temporally coordinated fibroblast growth factor signaling. J Neurosci 2004, 24:8711-8719.
70. Haubensak W., Attardo A., Denk W., Huttner W.B. Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: a major site of neurogenesis. Proc Natl Acad Sci U S A 2004, 101:3196-3201.
71. Heinrich C., Blum R., Gascon S., Masserdotti G., Tripathi P., Sanchez R., Tiedt S., Schroeder T., Gotz M., Berninger B. Directing astroglia from the cerebral cortex into subtype specific functional neurons. PLoS Biol 2010, 8:e1000373.
72. Heng J.I., Nguyen L., Castro D.S., Zimmer C., Wildner H., Armant O., Skowronska-Krawczyk D., Bedogni F., Matter J.M., Hevner R., Guillemot F. Neurogenin 2 controls cortical neuron migration through regulation of Rnd2. Nature 2008, 455:114-118.
73. Henke R.M., Meredith D.M., Borromeo M.D., Savage T.K., Johnson J.E. Ascl1 and Neurog2 form novel complexes and regulate Delta-like3 (Dll3) expression in the neural tube. Dev Biol 2009, 328:529-540.
74. Hindley C., Ali F., McDowell G., Cheng K., Jones A., Guillemot F., Philpott A. Post-translational modification of Ngn2 differentially affects transcription of distinct targets to regulate the balance between progenitor maintenance and differentiation. Development 2012, 139:1718-1723.
75. Hirabayashi Y., Itoh Y., Tabata H., Nakajima K., Akiyama T., Masuyama N., Gotoh Y. The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells. Development 2004, 131:2791-2801.
76. Hirabayashi Y., Suzki N., Tsuboi M., Endo T.A., Toyoda T., Shinga J., Koseki H., Vidal M., Gotoh Y. Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition. Neuron 2009, 63:600-613.
77. Ho L., Crabtree G.R. Chromatin remodelling during development. Nature 2010, 463:474-484.
78. Holm P.C., Mader M.T., Haubst N., Wizenmann A., Sigvardsson M., Gotz M. Loss- and gain-of-function analyses reveal targets of Pax6 in the developing mouse telencephalon. Mol Cell Neurosci 2007, 34:99-119.
79. Honjo T. The shortest path from the surface to the nucleus: RBP-J kappa/Su(H) transcription factor. Genes Cells 1996, 1:1-9.
80. Horton S., Meredith A., Richardson J.A., Johnson J.E. Correct coordination of neuronal differentiation events in ventral forebrain requires the bHLH factor MASH1. Mol Cell Neurosci 1999, 14:355-369.
81. Hsieh J., Gage F.H. Chromatin remodeling in neural development and plasticity. Curr Opin Cell Biol 2005, 17:664-671.
82. Huang H.P., Liu M., El-Hodiri H.M., Chu K., Jamrich M., Tsai M.J. Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3. Mol Cell Biol 2000, 20:3292-3307.
83. Huang S., Guo Y.P., May G., Enver T. Bifurcation dynamics in lineage-commitment in bipotent progenitor cells. Dev Biol 2007, 305:695-713.
84. Imayoshi I., Shimogori T., Ohtsuka T., Kageyama R. Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Development 2008, 135:2531-2541.
85. Institute A. Allen developing mouse brain atlas 2009, [Internet], Allen Institute for Brain Science.
86. Israsena N., Hu M., Fu W., Kan L., Kessler J.A. The presence of FGF2 signaling determines whether beta-catenin exerts effects on proliferation or neuronal differentiation of neural stem cells. Dev Biol 2004, 268:220-231.
87. Jakovcevski I., Filipovic R., Mo Z., Rakic S., Zecevic N. Oligodendrocyte development and the onset of myelination in the human fetal brain. Front Neuroanat 2009, 3:5.
88. Jakovcevski I., Mayer N., Zecevic N. Multiple origins of human neocortical interneurons are supported by distinct expression of transcription factors. Cereb Cortex 2011, 21:1771-1782.
89. Jarman A.P., Grell E.H., Ackerman L., Jan L.Y., Jan Y.N. Atonal is the proneural gene for Drosophila photoreceptors. Nature 1994, 369:398-400.
90. Jessberger S., Toni N., Clemenson G.D., Ray J., Gage F.H. Directed differentiation of hippocampal stem/progenitor cells in the adult brain. Nat Neurosci 2008, 11:888-893.
91. Johnson J.E., Birren S.J., Saito T., Anderson D.J. DNA binding and transcriptional regulatory activity of mammalian achaete-scute homologous (MASH) proteins revealed by interaction with a muscle-specific enhancer. Proc Natl Acad Sci U S A 1992, 89:3596-3600.
92. Ju B.G., Solum D., Song E.J., Lee K.J., Rose D.W., Glass C.K., Rosenfeld M.G. Activating the PARP-1 sensor component of the groucho/TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway. Cell 2004, 119:815-829.
93. Juliandi B., Abematsu M., Nakashima K. Epigenetic regulation in neural stem cell differentiation. Dev Growth Differ 2010, 52:493-504.
94. Kageyama R., Ohtsuka T., Kobayashi T. Roles of Hes genes in neural development. Dev Growth Differ 2008, 50(Suppl. 1):S97-103.
95. Kataoka A., Shimogori T. Fgf8 controls regional identity in the developing thalamus. Development 2008, 135:2873-2881.
96. Kendler K.S., Myers J.M., O'Neill F.A., Martin R., Murphy B., MacLean C.J., Walsh D., Straub R.E. Clinical features of schizophrenia and linkage to chromosomes 5q, 6p, 8p, and 10p in the Irish Study of High-Density Schizophrenia Families. Am J Psychiatry 2000, 157:402-408.
97. Kessaris N., Fogarty M., Iannarelli P., Grist M., Wegner M., Richardson W.D. Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage. Nat Neurosci 2006, 9:173-179.
98. Kishi Y., Fujii Y., Hirabayashi Y., Gotoh Y. HMGA regulates the global chromatin state and neurogenic potential in neocortical precursor cells. Nat Neurosci 2012, 15:1127-1133.
99. Knuckles P., Vogt M.A., Lugert S., Milo M., Chong M.M., Hautbergue G.M., Wilson S.A., Littman D.R., Taylor V. Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs. Nat Neurosci 2012, 15:962-969.
100. Kovach C., Dixit R., Li S., Mattar P., Wilkinson G., Elsen G.E., Kurrasch D.M., Hevner R.F., Schuurmans C. Neurog2 simultaneously activates and represses alternative gene expression programs in the developing neocortex. Cereb Cortex 2012, 23:1884-1900.
101. Kowalczyk T., Pontious A., Englund C., Daza R.A., Bedogni F., Hodge R., Attardo A., Bell C., Huttner W.B., Hevner R.F. Intermediate neuronal progenitors (basal progenitors) produce pyramidal-projection neurons for all layers of cerebral cortex. Cereb Cortex 2009, 19:2439-2450.
102. Kroll T.T., O'Leary D.D. Ventralized dorsal telencephalic progenitors in Pax6 mutant mice generate GABA interneurons of a lateral ganglionic eminence fate. Proc Natl Acad Sci U S A 2005, 102:7374-7379.
103. Ladewig J., Mertens J., Kesavan J., Doerr J., Poppe D., Glaue F., Herms S., Wernet P., Kogler G., Muller F.J., Koch P., Brustle O. Small molecules enable highly efficient neuronal conversion of human fibroblasts. Nat Methods 2012, 9:575-578.
104. Le-Niculescu H., Balaraman Y., Patel S., Tan J., Sidhu K., Jerome R.E., Edenberg H.J., Kuczenski R., Geyer M.A., Nurnberger J.I., Faraone S.V., Tsuang M.T., Niculescu A.B. Towards understanding the schizophrenia code: an expanded convergent functional genomics approach. Am J Med Genet B Neuropsychiatr Genet 2007, 144B:129-158.
105. Letinic K., Zoncu R., Rakic P. Origin of GABAergic neurons in the human neocortex. Nature 2002, 417:645-649.
106. Li S., Mattar P., Zinyk D., Singh K., Chaturvedi C.P., Kovach C., Dixit R., Kurrasch D.M., Ma Y.C., Chan J.A., Wallace V., Dilworth F.J., Brand M., Schuurmans C. GSK3 temporally regulates neurogenin 2 proneural activity in the neocortex. J Neurosci 2012, 32:7791-7805.
107. Ligon K.L., Alberta J.A., Kho A.T., Weiss J., Kwaan M.R., Nutt C.L., Louis D.N., Stiles C.D., Rowitch D.H. The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas. J Neuropathol Exp Neurol 2004, 63:499-509.
108. Ligon K.L., Huillard E., Mehta S., Kesari S., Liu H., Alberta J.A., Bachoo R.M., Kane M., Louis D.N., Depinho R.A., Anderson D.J., Stiles C.D., Rowitch D.H. Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma. Neuron 2007, 53:503-517.
109. Lukaszewicz A., Savatier P., Cortay V., Kennedy H., Dehay C. Contrasting effects of basic fibroblast growth factor and neurotrophin 3 on cell cycle kinetics of mouse cortical stem cells. J Neurosci 2002, 22:6610-6622.
110. Ma Y.C., Song M.R., Park J.P., Henry Ho H.Y., Hu L., Kurtev M.V., Zieg J., Ma Q., Pfaff S.L., Greenberg M.E. Regulation of motor neuron specification by phosphorylation of neurogenin 2. Neuron 2008, 58:65-77.
111. Machon O., Backman M., Krauss S., Kozmik Z. The cellular fate of cortical progenitors is not maintained in neurosphere cultures. Mol Cell Neurosci 2005, 30:388-397.
112. Marcus E.A., Kintner C., Harris W. The role of GSK3beta in regulating neuronal differentiation in Xenopus laevis. Mol Cell Neurosci 1998, 12:269-280.
113. Marin O., Rubenstein J.L. A long, remarkable journey: tangential migration in the telencephalon. Nat Rev Neurosci 2001, 2:780-790.
114. Marin O., Valdeolmillos M., Moya F. Neurons in motion: same principles for different shapes?. Trends Neurosci 2006, 29:655-661.
115. Mattar P., Britz O., Johannes C., Nieto M., Ma L., Rebeyka A., Klenin N., Polleux F., Guillemot F., Schuurmans C. A screen for downstream effectors of neurogenin2 in the embryonic neocortex. Dev Biol 2004, 273:373-389.
116. Mattar P., Langevin L.M., Markham K., Klenin N., Shivji S., Zinyk D., Schuurmans C. Basic helix-loop-helix transcription factors cooperate to specify a cortical projection neuron identity. Mol Cell Biol 2008, 28:1456-1469.
117. McDowell G.S., Kucerova R., Philpott A. Non-canonical ubiquitylation of the proneural protein Ngn2 occurs in both Xenopus embryos and mammalian cells. Biochem Biophys Res Commun 2010, 400:655-660.
118. Meredith A., Johnson J.E. Negative autoregulation of Mash1 expression in CNS development. Dev Biol 2000, 222:336-346.
119. Miller F.D., Gauthier A.S. Timing is everything: making neurons versus glia in the developing cortex. Neuron 2007, 54:357-369.
120. Miyata T., Kawaguchi A., Saito K., Kawano M., Muto T., Ogawa M. Asymmetric production of surface-dividing and non-surface-dividing cortical progenitor cells. Development 2004, 131:3133-3145.
121. Mizuguchi R., Sugimori M., Takebayashi H., Kosako H., Nagao M., Yoshida S., Nabeshima Y., Shimamura K., Nakafuku M. Combinatorial roles of olig2 and neurogenin2 in the coordinated induction of pan-neuronal and subtype-specific properties of motoneurons. Neuron 2001, 31:757-771.
122. Mohamed Ariff I., Mitra A., Basu A. Epigenetic regulation of self-renewal and fate determination in neural stem cells. J Neurosci Res 2011, 90:529-539.
123. Molyneaux B.J., Arlotta P., Hirata T., Hibi M., Macklis J.D. Fezl is required for the birth and specification of corticospinal motor neurons. Neuron 2005, 47:817-831.
124. Moore K.B., Schneider M.L., Vetter M.L. Posttranslational mechanisms control the timing of bHLH function and regulate retinal cell fate. Neuron 2002, 34:183-195.
125. Murre C., McCaw P.S., Vaessin H., Caudy M., Jan L.Y., Jan Y.N., Cabrera C.V., Buskin J.N., Hauschka S.D., Lassar A.B., et al. Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence. Cell 1989, 58:537-544.
126. Muzio L., Di Benedetto B., Stoykova A., Boncinelli E., Gruss P., Mallamaci A. Emx2 and Pax6 control regionalization of the pre-neuronogenic cortical primordium. Cereb Cortex 2002, 12:129-139.
127. Muzio L., DiBenedetto B., Stoykova A., Boncinelli E., Gruss P., Mallamaci A. Conversion of cerebral cortex into basal ganglia in Emx2(-/-) Pax6(Sey/Sey) double-mutant mice. Nat Neurosci 2002, 5:737-745.
128. Nadarajah B., Brunstrom J.E., Grutzendler J., Wong R.O., Pearlman A.L. Two modes of radial migration in early development of the cerebral cortex. Nat Neurosci 2001, 4:143-150.
129. Najmabadi H., Hu H., Garshasbi M., Zemojtel T., Abedini S.S., Chen W., Hosseini M., Behjati F., Haas S., Jamali P., Zecha A., Mohseni M., Puttmann L., Vahid L.N., Jensen C., Moheb L.A., Bienek M., Larti F., Mueller I., Weissmann R., Darvish H., Wrogemann K., Hadavi V., Lipkowitz B., Esmaeeli-Nieh S., Wieczorek D., Kariminejad R., Firouzabadi S.G., Cohen M., Fattahi Z., Rost I., Mojahedi F., Hertzberg C., Dehghan A., Rajab A., Banavandi M.J., Hoffer J., Falah M., Musante L., Kalscheuer V., Ullmann R., Kuss A.W., Tzschach A., Kahrizi K., Ropers H.H. Deep sequencing reveals 50 novel genes for recessive cognitive disorders. Nature 2011, 478:57-63.
130. Nakamura F. FilGAP and its close relatives: a mediator of Rho-Rac antagonism that regulates cell morphology and migration. Biochem J 2013, 453:17-25.
131. Nakatani H., Martin E., Hassani H., Clavairoly A., Maire C.L., Viadieu A., Kerninon C., Delmasure A., Frah M., Weber M., Nakafuku M., Zalc B., Thomas J.L., Guillemot F., Nait-Oumesmar B., Parras C. Ascl1/Mash1 promotes brain oligodendrogenesis during myelination and remyelination. J Neurosci 2013, 33:9752-9768.
132. Nery S., Fishell G., Corbin J.G. The caudal ganglionic eminence is a source of distinct cortical and subcortical cell populations. Nat Neurosci 2002, 5:1279-1287.
133. Nguyen L., Besson A., Heng J.I., Schuurmans C., Teboul L., Parras C., Philpott A., Roberts J.M., Guillemot F. P27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex. Genes Dev 2006, 20:1511-1524.
134. Nieto M., Schuurmans C., Britz O., Guillemot F. Neural bHLH genes control the neuronal versus glial fate decision in cortical progenitors. Neuron 2001, 29:401-413.
135. Novitch B.G., Chen A.I., Jessell T.M. Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH repressor Olig2. Neuron 2001, 31:773-789.
136. Ochiai W., Nakatani S., Takahara T., Kainuma M., Masaoka M., Minobe S., Namihira M., Nakashima K., Sakakibara A., Ogawa M., Miyata T. Periventricular notch activation and asymmetric Ngn2 and Tbr2 expression in pair-generated neocortical daughter cells. Mol Cell Neurosci 2009, 40:225-233.
137. Ohkawara T., Shintani T., Saegusa C., Yuasa-Kawada J., Takahashi M., Noda M. A novel basic helix-loop-helix (bHLH) transcriptional repressor, NeuroAB, expressed in bipolar and amacrine cells in the chick retina. Brain Res Mol Brain Res 2004, 128:58-74.
138. Ohsako S., Hyer J., Panganiban G., Oliver I., Caudy M. Hairy function as a DNA-binding helix-loop-helix repressor of Drosophila sensory organ formation. Genes Dev 1994, 8:2743-2755.
139. Ohtaka-Maruyama C., Hirai S., Miwa A., Heng J.I., Shitara H., Ishii R., Taya C., Kawano H., Kasai M., Nakajima K., Okado H. RP58 regulates the multipolar-bipolar transition of newborn neurons in the developing cerebral cortex. Cell Rep 2013, 3:458-471.
140. Ohtsuka T., Ishibashi M., Gradwohl G., Nakanishi S., Guillemot F., Kageyama R. Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation. EMBO J 1999, 18:2196-2207.
141. Onoguchi M., Hirabayashi Y., Koseki H., Gotoh Y. A noncoding RNA regulates the neurogenin1 gene locus during mouse neocortical development. Proc Natl Acad Sci U S A 2012, 109:16939-16944.
142. Otero J.J., Rowitch D., Vandenberg S. OLIG2 is differentially expressed in pediatric astrocytic and in ependymal neoplasms. J Neurooncol 2011, 104:423-438.
143. Pacary E., Heng J., Azzarelli R., Riou P., Castro D., Lebel-Potter M., Parras C., Bell D.M., Ridley A.J., Parsons M., Guillemot F. Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling. Neuron 2011, 69:1069-1084.
144. Pang Z.P., Yang N., Vierbuchen T., Ostermeier A., Fuentes D.R., Yang T.Q., Citri A., Sebastiano V., Marro S., Sudhof T.C., Wernig M. Induction of human neuronal cells by defined transcription factors. Nature 2011, 476:220-223.
145. Parras C.M., Galli R., Britz O., Soares S., Galichet C., Battiste J., Johnson J.E., Nakafuku M., Vescovi A., Guillemot F. Mash1 specifies neurons and oligodendrocytes in the postnatal brain. EMBO J 2004, 23:4495-4505.
146. Parras C.M., Hunt C., Sugimori M., Nakafuku M., Rowitch D., Guillemot F. The proneural gene Mash1 specifies an early population of telencephalic oligodendrocytes. J Neurosci 2007, 27:4233-4242.
147. Parras C.M., Schuurmans C., Scardigli R., Kim J., Anderson D.J., Guillemot F. Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identity. Genes Dev 2002, 16:324-338.
148. Paugh B.S., Qu C., Jones C., Liu Z., Adamowicz-Brice M., Zhang J., Bax D.A., Coyle B., Barrow J., Hargrave D., Lowe J., Gajjar A., Zhao W., Broniscer A., Ellison D.W., Grundy R.G., Baker S.J. Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease. J Clin Oncol 2010, 28:3061-3068.
149. Penn B.H., Bergstrom D.A., Dilworth F.J., Bengal E., Tapscott S.J. A MyoD-generated feed-forward circuit temporally patterns gene expression during skeletal muscle differentiation. Genes Dev 2004, 18:2348-2353.
150. Petanjek Z., Berger B., Esclapez M. Origins of cortical GABAergic neurons in the cynomolgus monkey. Cereb Cortex 2009, 19:249-262.
151. Pfisterer U., Kirkeby A., Torper O., Wood J., Nelander J., Dufour A., Bjorklund A., Lindvall O., Jakobsson J., Parmar M. Direct conversion of human fibroblasts to dopaminergic neurons. Proc Natl Acad Sci U S A 2011, 108:10343-10348.
152. Phillips H.S., Kharbanda S., Chen R., Forrest W.F., Soriano R.H., Wu T.D., Misra A., Nigro J.M., Colman H., Soroceanu L., Williams P.M., Modrusan Z., Feuerstein B.G., Aldape K. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 2006, 9:157-173.
153. Piper M., Barry G., Hawkins J., Mason S., Lindwall C., Little E., Sarkar A., Smith A.G., Moldrich R.X., Boyle G.M., Tole S., Gronostajski R.M., Bailey T.L., Richards L.J. NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci 2010, 30:9127-9139.
154. Poitras L., Ghanem N., Hatch G., Ekker M. The proneural determinant MASH1 regulates forebrain Dlx1/2 expression through the I12b intergenic enhancer. Development 2007, 134:1755-1765.
155. Polleux F., Lauder J.M. Toward a developmental neurobiology of autism. Ment Retard Dev Disabil Res Rev 2004, 10:303-317.
156. Ribes V., Stutzmann F., Bianchetti L., Guillemot F., Dolle P., Le Roux I. Combinatorial signalling controls neurogenin2 expression at the onset of spinal neurogenesis. Dev Biol 2008, 321:470-481.
157. Ross S.E., Greenberg M.E., Stiles C.D. Basic helix-loop-helix factors in cortical development. Neuron 2003, 39:13-25.
158. Salomoni P., Calegari F. Cell cycle control of mammalian neural stem cells: putting a speed limit on G1. Trends Cell Biol 2010, 20:233-243.
159. Sansom S.N., Griffiths D.S., Faedo A., Kleinjan D.J., Ruan Y., Smith J., van Heyningen V., Rubenstein J.L., Livesey F.J. The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet 2009, 5:e1000511.
160. Scardigli R., Baumer N., Gruss P., Guillemot F., Le Roux I. Direct and concentration-dependent regulation of the proneural gene neurogenin2 by Pax6. Development 2003, 130:3269-3281.
161. Schuurmans C., Armant O., Nieto M., Stenman J.M., Britz O., Klenin N., Brown C., Langevin L.M., Seibt J., Tang H., Cunningham J.M., Dyck R., Walsh C., Campbell K., Polleux F., Guillemot F. Sequential phases of cortical specification involve neurogenin-dependent and -independent pathways. EMBO J 2004, 23:2892-2902.
162. Schwab S.G., Eckstein G.N., Hallmayer J., Lerer B., Albus M., Borrmann M., Lichtermann D., Ertl M.A., Maier W., Wildenauer D.B. Evidence suggestive of a locus on chromosome 5q31 contributing to susceptibility for schizophrenia in German and Israeli families by multipoint affected sib-pair linkage analysis. Mol Psychiatry 1997, 2:156-160.
163. Segklia A., Seuntjens E., Elkouris M., Tsalavos S., Stappers E., Mitsiadis T.A., Huylebroeck D., Remboutsika E., Graf D. Bmp7 regulates the survival, proliferation, and neurogenic properties of neural progenitor cells during corticogenesis in the mouse. PLoS One 2012, 7:e34088.
164. Selkoe D., Kopan R. Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration. Annu Rev Neurosci 2003, 26:565-597.
165. Seo S., Lim J.W., Yellajoshyula D., Chang L.W., Kroll K.L. Neurogenin and NeuroD direct transcriptional targets and their regulatory enhancers. EMBO J 2007, 26:5093-5108.
166. Seo S., Richardson G.A., Kroll K.L. The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD. Development 2005, 132:105-115.
167. Sequeira A., Turecki G. Genome wide gene expression studies in mood disorders. OMICS 2006, 10:444-454.
168. Sessa A., Mao C.A., Hadjantonakis A.K., Klein W.H., Broccoli V. Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex. Neuron 2008, 60:56-69.
169. Shaker T., Dennis D., Kurrasch D.M., Schuurmans C. Neurog1 and Neurog2 coordinately regulate development of the olfactory system. Neural Dev 2012, 7:28.
170. Shankaran H., Ippolito D.L., Chrisler W.B., Resat H., Bollinger N., Opresko L.K., Wiley H.S. Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor. Mol Syst Biol 2009, 5:332.
171. Shi Y., Zhao X., Hsieh J., Wichterle H., Impey S., Banerjee S., Neveu P., Kosik K.S. MicroRNA regulation of neural stem cells and neurogenesis. J Neurosci 2010, 30:14931-14936.
172. Shimizu T., Nakazawa M., Kani S., Bae Y.K., Shimizu T., Kageyama R., Hibi M. Zinc finger genes Fezf1 and Fezf2 control neuronal differentiation by repressing Hes5 expression in the forebrain. Development 2010, 137:1875-1885.
173. Shimojo H., Ohtsuka T., Kageyama R. Oscillations in notch signaling regulate maintenance of neural progenitors. Neuron 2008, 58:52-64.
174. Shimojo H., Ohtsuka T., Kageyama R. Dynamic expression of notch signaling genes in neural stem/progenitor cells. Front Neurosci 2011, 5:78.
175. Skol A.D., Young K.A., Tsuang D.W., Faraone S.V., Haverstock S.L., Bingham S., Prabhudesai S., Mena F., Menon A.S., Yu C.E., Rundell P., Pepple J., Sauter F., Baldwin C., Weiss D., Collins J., Keith T., Boehnke M., Schellenberg G.D., Tsuang M.T. Modest evidence for linkage and possible confirmation of association between NOTCH4 and schizophrenia in a large Veterans Affairs Cooperative Study sample. Am J Med Genet B Neuropsychiatr Genet 2003, 118B:8-15.
176. Skowronska-Krawczyk D., Ballivet M., Dynlacht B.D., Matter J.M. Highly specific interactions between bHLH transcription factors and chromatin during retina development. Development 2004, 131:4447-4454.
177. Smart I.H., Smart M. The location of nuclei of different labelling intensities in autoradiographs of the anterior forebrain of postnatial mice injected with [3H]thymidine on the eleventh and twelfth days post-conception. J Anat 1977, 123:515-525.
178. Stoykova A., Treichel D., Hallonet M., Gruss P. Pax6 modulates the dorsoventral patterning of the mammalian telencephalon. J Neurosci 2000, 20:8042-8050.
179. Strasser M., Theis F.J., Marr C. Stability and multiattractor dynamics of a toggle switch based on a two-stage model of stochastic gene expression. Biophys J 2012, 102:19-29.
180. Subramanian L., Sarkar A., Shetty A.S., Muralidharan B., Padmanabhan H., Piper M., Monuki E.S., Bach I., Gronostajski R.M., Richards L.J., Tole S. Transcription factor Lhx2 is necessary and sufficient to suppress astrogliogenesis and promote neurogenesis in the developing hippocampus. Proc Natl Acad Sci U S A 2011, 108:E265-274.
181. Sun Y., Nadal-Vicens M., Misono S., Lin M.Z., Zubiaga A., Hua X., Fan G., Greenberg M.E. Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms. Cell 2001, 104:365-376.
182. Super H., Soriano E., Uylings H.B. The functions of the preplate in development and evolution of the neocortex and hippocampus. Brain Res Brain Res Rev 1998, 27:40-64.
183. Takahashi T., Goto T., Miyama S., Nowakowski R.S., Caviness V.S. Sequence of neuron origin and neocortical laminar fate: relation to cell cycle of origin in the developing murine cerebral wall. J Neurosci 1999, 19:10357-10371.
184. Tamamaki N., Fujimori K.E., Takauji R. Origin and route of tangentially migrating neurons in the developing neocortical intermediate zone. J Neurosci 1997, 17:8313-8323.
185. Tapscott S.J. The circuitry of a master switch: Myod and the regulation of skeletal muscle gene transcription. Development 2005, 132:2685-2695.
186. Theil T., Alvarez-Bolado G., Walter A., Ruther U. Gli3 is required for Emx gene expression during dorsal telencephalon development. Development 1999, 126:3561-3571.
187. Tole S., Ragsdale C.W., Grove E.A. Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J). Dev Biol 2000, 217:254-265.
188. Vierbuchen T., Ostermeier A., Pang Z.P., Kokubu Y., Sudhof T.C., Wernig M. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 2010, 463:1035-1041.
189. Villares R., Cabrera C.V. The achaete-scute gene complex of D. melanogaster: conserved domains in a subset of genes required for neurogenesis and their homology to myc. Cell 1987, 50:415-424.
190. Vinals F., Reiriz J., Ambrosio S., Bartrons R., Rosa J.L., Ventura F. BMP-2 decreases Mash1 stability by increasing Id1 expression. EMBO J 2004, 23:3527-3537.
191. Vosper J.M., Fiore-Heriche C.S., Horan I., Wilson K., Wise H., Philpott A. Regulation of neurogenin stability by ubiquitin-mediated proteolysis. Biochem J 2007, 407:277-284.
192. Watanabe K., Kamiya D., Nishiyama A., Katayama T., Nozaki S., Kawasaki H., Watanabe Y., Mizuseki K., Sasai Y. Directed differentiation of telencephalic precursors from embryonic stem cells. Nat Neurosci 2005, 8:288-296.
193. Wontakal S.N., Guo X., Smith C., Maccarthy T., Bresnick E.H., Bergman A., Snyder M.P., Weissman S.M., Zheng D., Skoultchi A.I. A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation. Proc Natl Acad Sci U S A 2012, 109:3832-3837.
194. Xu Q., Cobos I., De La Cruz E., Rubenstein J.L., Anderson S.A. Origins of cortical interneuron subtypes. J Neurosci 2004, 24:2612-2622.
195. Xu Q., de la Cruz E., Anderson S.A. Cortical interneuron fate determination: diverse sources for distinct subtypes?. Cereb Cortex 2003, 13:670-676.
196. Yoo A.S., Sun A.X., Li L., Shcheglovitov A., Portmann T., Li Y., Lee-Messer C., Dolmetsch R.E., Tsien R.W., Crabtree G.R. MicroRNA-mediated conversion of human fibroblasts to neurons. Nature 2011, 476:228-231.
197. Yu X., Zecevic N. Dorsal radial glial cells have the potential to generate cortical interneurons in human but not in mouse brain. J Neurosci 2011, 31:2413-2420.
198. Zaharieva I., Georgieva L., Nikolov I., Kirov G., Owen M.J., O'Donovan M.C., Toncheva D. Association study in the 5q31-32 linkage region for schizophrenia using pooled DNA genotyping. BMC Psychiatry 2008, 8:11.
199. Zandi S., Bryder D., Sigvardsson M. Load and lock: the molecular mechanisms of B-lymphocyte commitment. Immunol Rev 2010, 238:47-62.
200. Zhang P., Zhang X., Iwama A., Yu C., Smith K.A., Mueller B.U., Narravula S., Torbett B.E., Orkin S.H., Tenen D.G. PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding. Blood 2000, 96:2641-2648.
201. Zhang Y., Pak C., Han Y., Ahlenius H., Zhang Z., Chanda S., Marro S., Patzke C., Acuna C., Covy J., Xu W., Yang N., Danko T., Chen L., Wernig M., Sudhof T.C. Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron 2013, 78:785-798.