PDGFRA amplification is common in pediatric and adult high-grade astrocytomas and identifies a poor prognostic group in IDH1 mutant glioblastoma

Brain Pathology

Volumn 23, Issue 5, 2013, Pages 565-573

  Phillips, Joanna J ^a,b   Aranda, Derick ^a,b   Ellison, David W ^f   Judkins, Alexander R ^d   Croul, Sidney E ⁿ   Brat, Daniel J ^g   Ligon, Keith L ^h   Horbinski, Craig ^j   Venneti, Sriram ^k   Zadeh, Gelareh ^o   Santi, Mariarita ^l   Zhou, Shengmei ^d   Appin, Christina L ^g   Sioletic, Stefano ⁱ   Sullivan, Lisa M ^l   Martinez Lage, Maria ^m   Robinson, Aaron E ^a,b   Yong, William H ^e   Cloughesy, Timothy ^e   Lai, Albert ^e   Phillips, Heidi S ^c   Marshall, Roxanne ^a,b   Mueller, Sabine ^b   Haas Kogan, Daphne A ^a,b   Molinaro, Annette M ^a,b   Perry, Arie ^a,b   more..

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GENENTECH INC   (United States)

^d CHILDREN S HOSPITAL LOS ANGELES   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^g EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h DANA FARBER CANCER INSTITUTE   (United States)

ⁱ BRIGHAM AND WOMEN S HOSPITAL   (United States)

^j UNIVERSITY OF KENTUCKY   (United States)

^k MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^l CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^m UNIVERSITY OF PENNSYLVANIA   (United States)

ⁿ UNIVERSITY OF TORONTO   (Canada)

^o UNIVERSITY OF TORONTO   (Canada)

more..

Author keywords

Astrocytoma; FISH; IDH1; isocitrate dehydrogenase 1; PDGFRA; prognosis

Indexed keywords

ISOCITRATE DEHYDROGENASE 1; PLATELET DERIVED GROWTH FACTOR A;

ADOLESCENT; ADULT; AGED; ARTICLE; ASTROCYTOMA; CANCER PROGNOSIS; CHILD; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GAIN OF FUNCTION MUTATION; GENE DOSAGE; GLIOBLASTOMA; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM;

ASTROCYTOMA; FISH; IDH1; ISOCITRATE DEHYDROGENASE 1; PDGFRA; PROGNOSIS;

ADOLESCENT; ADULT; ASTROCYTOMA; BRAIN NEOPLASMS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DNA COPY NUMBER VARIATIONS; FEMALE; GLIOBLASTOMA; HUMANS; ISOCITRATE DEHYDROGENASE; MALE; MIDDLE AGED; MUTATION; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; SEX FACTORS; STATISTICS, NONPARAMETRIC; YOUNG ADULT;

EID: 84882247189     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/bpa.12043     Document Type: Article

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