-
1
-
-
84862877433
-
Effects of hypoxia and HIFs on cancer metabolism
-
Mucaj V, Shay J, Simon M (2012) Effects of hypoxia and HIFs on cancer metabolism. Int J Hematol 95(5):464-470. doi:10.1007/s12185-012-1070-5
-
(2012)
Int J Hematol
, vol.95
, Issue.5
, pp. 464-470
-
-
Mucaj, V.1
Shay, J.2
Simon, M.3
-
2
-
-
79957534572
-
Targeting hypoxia in cancer therapy
-
Wilson WR, Hay MP (2011) Targeting hypoxia in cancer therapy. Nat Rev Cancer 11(6):393-410. doi:10.1038/nrc3064
-
(2011)
Nat Rev Cancer
, vol.11
, Issue.6
, pp. 393-410
-
-
Wilson, W.R.1
Hay, M.P.2
-
3
-
-
84859870939
-
Recent developments in targeting carbonic anhydrase IX for cancer therapeutics
-
McDonald PC, Winum JY, Supuran CT, Dedhar S (2012) Recent developments in targeting carbonic anhydrase IX for cancer therapeutics. Oncotarget 3(1):84-97
-
(2012)
Oncotarget
, vol.3
, Issue.1
, pp. 84-97
-
-
McDonald, P.C.1
Winum, J.Y.2
Supuran, C.T.3
Dedhar, S.4
-
4
-
-
34548317034
-
Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer
-
Gatenby RA, Smallbone K, Maini PK, Rose F, Averill J, Nagle RB, Worrall L, Gillies RJ (2007) Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer. Br J Cancer 97(5):646-653. doi:10.1038/sj.bjc.6603922
-
(2007)
Br J Cancer
, vol.97
, Issue.5
, pp. 646-653
-
-
Gatenby, R.A.1
Smallbone, K.2
Maini, P.K.3
Rose, F.4
Averill, J.5
Nagle, R.B.6
Worrall, L.7
Gillies, R.J.8
-
5
-
-
37549013776
-
A microenvironmental model of carcinogenesis
-
Gatenby RA, Gillies RJ (2008) A microenvironmental model of carcinogenesis. Nat Rev Cancer 8(1):56-61. doi:10.1038/nrc2255
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.1
, pp. 56-61
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
6
-
-
58249094845
-
Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH
-
Chiche J, Ilc K, Laferriere J, Trottier E, Dayan F, Mazure NM, Brahimi-Horn MC, Pouyssegur J (2009) Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH. Cancer Res 69(1):358-368. doi: 10.1158/0008-5472.can-08-2470
-
(2009)
Cancer Res
, vol.69
, Issue.1
, pp. 358-368
-
-
Chiche, J.1
Ilc, K.2
Laferriere, J.3
Trottier, E.4
Dayan, F.5
Mazure, N.M.6
Brahimi-Horn, M.C.7
Pouyssegur, J.8
-
7
-
-
55549090009
-
Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes
-
Hilvo M, Baranauskiene L, Salzano AM, Scaloni A, Matulis D, Innocenti A, Scozzafava A, Monti SM, Di Fiore A, De Simone G, Lindfors M, Janis J, Valjakka J, Pastorekova S, Pastorek J, Kulomaa MS, Nordlund HR, Supuran CT, Parkkila S (2008) Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes. J Biol Chem 283(41):27799-27809. doi: 10.1074/jbc.M800938200
-
(2008)
J Biol Chem
, vol.283
, Issue.41
, pp. 27799-27809
-
-
Hilvo, M.1
Baranauskiene, L.2
Salzano, A.M.3
Scaloni, A.4
Matulis, D.5
Innocenti, A.6
Scozzafava, A.7
Monti, S.M.8
Di Fiore, A.9
De Simone, G.10
Lindfors, M.11
Janis, J.12
Valjakka, J.13
Pastorekova, S.14
Pastorek, J.15
Kulomaa, M.S.16
Nordlund, H.R.17
Supuran, C.T.18
Parkkila, S.19
-
8
-
-
84860491757
-
Role of zinc in catalytic activity of carbonic anhydrase IX
-
Tu C, Foster L, Alvarado A, McKenna R, Silverman DN, Frost SC (2012) Role of zinc in catalytic activity of carbonic anhydrase IX. Arch Biochem Biophys 521(1-2):90-94. doi:10.1016/j.abb.2012.03.017
-
(2012)
Arch Biochem Biophys
, vol.521
, Issue.1-2
, pp. 90-94
-
-
Tu, C.1
Foster, L.2
Alvarado, A.3
McKenna, R.4
Silverman, D.N.5
Frost, S.C.6
-
9
-
-
0026561063
-
A novel quasi-viral agent, MaTu, is a two-component system
-
Pastorekova S, Zavadova Z, Kostal M, Babusikova O, Zavada J (1992) A novel quasi-viral agent, MaTu, is a two-component system. Virology 187(2):620-626
-
(1992)
Virology
, vol.187
, Issue.2
, pp. 620-626
-
-
Pastorekova, S.1
Zavadova, Z.2
Kostal, M.3
Babusikova, O.4
Zavada, J.5
-
10
-
-
0027153461
-
Expression of MaTu-MN protein in human tumor cultures and in clinical specimens
-
Zavada J, Zavadova Z, Pastorekova S, Ciampor F, Pastorek J, Zelnik V (1993) Expression of MaTu-MN protein in human tumor cultures and in clinical specimens. Int J Cancer 54(2):268-274
-
(1993)
Int J Cancer
, vol.54
, Issue.2
, pp. 268-274
-
-
Zavada, J.1
Zavadova, Z.2
Pastorekova, S.3
Ciampor, F.4
Pastorek, J.5
Zelnik, V.6
-
11
-
-
0028111173
-
Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment
-
Pastorek J, Pastorekova S, Callebaut I, Mornon JP, Zelnik V, Opavsky R, Zat'ovicova M, Liao S, Portetelle D, Stanbridge EJ, Zavada J, Burny A, Kettman R (1994) Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment. Oncogene 9(10):2877-2888
-
(1994)
Oncogene
, vol.9
, Issue.10
, pp. 2877-2888
-
-
Pastorek, J.1
Pastorekova, S.2
Callebaut, I.3
Mornon, J.P.4
Zelnik, V.5
Opavsky, R.6
Zat'ovicova, M.7
Liao, S.8
Portetelle, D.9
Stanbridge, E.J.10
Zavada, J.11
Burny, A.12
Kettman, R.13
-
12
-
-
0029975564
-
Human MN/CA9 gene, a novel member of the carbonic anhydrase family: Structure and exon to protein domain relationships
-
Opavsky R, Pastorekova S, Zelnik V, Gibadulinova A, Stanbridge EJ, Zavada J, Kettmann R, Pastorek J (1996) Human MN/CA9 gene, a novel member of the carbonic anhydrase family: structure and exon to protein domain relationships. Genomics 33(3):480-487. doi: 10.1006/geno.1996.0223
-
(1996)
Genomics
, vol.33
, Issue.3
, pp. 480-487
-
-
Opavsky, R.1
Pastorekova, S.2
Zelnik, V.3
Gibadulinova, A.4
Stanbridge, E.J.5
Zavada, J.6
Kettmann, R.7
Pastorek, J.8
-
13
-
-
0034099829
-
Molecular cloning and immunogenicity of renal cell carcinoma-associated antigen G250
-
Grabmaier K, Vissers JL, De Weijert MC, Oosterwijk-Wakka JC, Van Bokhoven A, Brakenhoff RH, Noessner E, Mulders PA, Merkx G, Figdor CG, Adema GJ, Oosterwijk E (2000) Molecular cloning and immunogenicity of renal cell carcinoma-associated antigen G250. Int J Cancer 85(6):865-870
-
(2000)
Int J Cancer
, vol.85
, Issue.6
, pp. 865-870
-
-
Grabmaier, K.1
Vissers, J.L.2
De Weijert, M.C.3
Oosterwijk-Wakka, J.C.4
Van Bokhoven, A.5
Brakenhoff, R.H.6
Noessner, E.7
Mulders, P.A.8
Merkx, G.9
Figdor, C.G.10
Adema, G.J.11
Oosterwijk, E.12
-
14
-
-
0034024783
-
Human tumour-associated cell adhesion protein MN/CA IX: Identification of M75 epitope and of the region mediating cell adhesion
-
Zavada J, Zavadova Z, Pastorek J, Biesova Z, Jezek J, Velek J (2000) Human tumour-associated cell adhesion protein MN/CA IX: identification of M75 epitope and of the region mediating cell adhesion. Br J Cancer 82(11):1808-1813. doi:10.1054/bjoc.2000.1111
-
(2000)
Br J Cancer
, vol.82
, Issue.11
, pp. 1808-1813
-
-
Zavada, J.1
Zavadova, Z.2
Pastorek, J.3
Biesova, Z.4
Jezek, J.5
Velek, J.6
-
15
-
-
38049077062
-
Alternative splicing variant of the hypoxia marker carbonic anhydrase IX expressed independently of hypoxia and tumour phenotype
-
Barathova M, Takacova M, Holotnakova T, Gibadulinova A, Ohradanova A, Zatovicova M, Hulikova A, Kopacek J, Parkkila S, Supuran CT, Pastorekova S, Pastorek J (2008) Alternative splicing variant of the hypoxia marker carbonic anhydrase IX expressed independently of hypoxia and tumour phenotype. Br J Cancer 98(1):129-136. doi:10.1038/sj.bjc.6604111
-
(2008)
Br J Cancer
, vol.98
, Issue.1
, pp. 129-136
-
-
Barathova, M.1
Takacova, M.2
Holotnakova, T.3
Gibadulinova, A.4
Ohradanova, A.5
Zatovicova, M.6
Hulikova, A.7
Kopacek, J.8
Parkkila, S.9
Supuran, C.T.10
Pastorekova, S.11
Pastorek, J.12
-
16
-
-
67349229817
-
Alternative splicing variants of carbonic anhydrase IX in human non-small cell lung cancer
-
Malentacchi F, Simi L, Nannelli C, Andreani M, Janni A, Pastorekova S, Orlando C (2009) Alternative splicing variants of carbonic anhydrase IX in human non-small cell lung cancer. Lung Cancer 64(3):271-276. doi:10.1016/j.lungcan.2008.10.001
-
(2009)
Lung Cancer
, vol.64
, Issue.3
, pp. 271-276
-
-
Malentacchi, F.1
Simi, L.2
Nannelli, C.3
Reani, M.4
Janni, A.5
Pastorekova, S.6
Orlando, C.7
-
17
-
-
70349490906
-
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX
-
Alterio V, Hilvo M, Di Fiore A, Supuran CT, Pan PW, Parkkila S, Scaloni A, Pastorek J, Pastorekova S, Pedone C, Scozzafava A, Monti SM, De Simone G (2009) Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX. Proc Natl Acad Sci U S A 106(38):16233-16238. doi:10.1073/pnas.0908301106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.38
, pp. 16233-16238
-
-
Alterio, V.1
Hilvo, M.2
Di Fiore, A.3
Supuran, C.T.4
Pan, P.W.5
Parkkila, S.6
Scaloni, A.7
Pastorek, J.8
Pastorekova, S.9
Pedone, C.10
Scozzafava, A.11
Monti, S.M.12
De Simone, G.13
-
18
-
-
74449091486
-
Carbonic anhydrase IX: Biochemical and crystallo-graphic characterization of a novel antitumor target
-
De Simone G, Supuran CT (2010) Carbonic anhydrase IX: biochemical and crystallo-graphic characterization of a novel antitumor target. Biochim Biophys Acta 1804(2):404-409. doi:10.1016/j.bbapap.2009.07.027
-
(2010)
Biochim Biophys Acta
, vol.1804
, Issue.2
, pp. 404-409
-
-
De Simone, G.1
Supuran, C.T.2
-
19
-
-
70349199011
-
The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as an intrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors
-
Innocenti A, Pastorekova S, Pastorek J, Scozzafava A, De Simone G, Supuran CT (2009) The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as an intrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors. Bioorg Med Chem Lett 19(20):5825-5828. doi:10.1016/j.bmcl.2009.08.088
-
(2009)
Bioorg Med Chem Lett
, vol.19
, Issue.20
, pp. 5825-5828
-
-
Innocenti, A.1
Pastorekova, S.2
Pastorek, J.3
Scozzafava, A.4
De Simone, G.5
Supuran, C.T.6
-
20
-
-
8844249356
-
Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH
-
Svastova E, Hulikova A, Rafajova M, Zat'ovicova M, Gibadulinova A, Casini A, Cecchi A, Scozzafava A, Supuran CT, Pastorek J, Pastorekova S (2004) Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH. FEBS Lett 577(3):439-445. doi:10.1016/j.febslet.2004.10.043
-
(2004)
FEBS Lett
, vol.577
, Issue.3
, pp. 439-445
-
-
Svastova, E.1
Hulikova, A.2
Rafajova, M.3
Zat'ovicova, M.4
Gibadulinova, A.5
Casini, A.6
Cecchi, A.7
Scozzafava, A.8
Supuran, C.T.9
Pastorek, J.10
Pastorekova, S.11
-
21
-
-
43549121719
-
The Warburg effect: Why and how do cancer cells activate glycolysis in the presence of oxygen?
-
Lopez-Lazaro M (2008) The Warburg effect: why and how do cancer cells activate glycolysis in the presence of oxygen? Anti-Cancer Agents in Medicinal Chemistry 8(3):305-312
-
(2008)
Anti-Cancer Agents in Medicinal Chemistry
, vol.8
, Issue.3
, pp. 305-312
-
-
Lopez-Lazaro, M.1
-
22
-
-
0037463790
-
Carbonic anhydrase inhibitors: Inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides
-
Vullo D, Franchi M, Gallori E, Pastorek J, Scozzafava A, Pastorekova S, Supuran CT (2003) Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides. Bioorg Med Chem Lett 13(6):1005-1009
-
(2003)
Bioorg Med Chem Lett
, vol.13
, Issue.6
, pp. 1005-1009
-
-
Vullo, D.1
Franchi, M.2
Gallori, E.3
Pastorek, J.4
Scozzafava, A.5
Pastorekova, S.6
Supuran, C.T.7
-
23
-
-
77953373415
-
Proton dynamics in cancer
-
Huber V, De Milito A, Harguindey S, Reshkin SJ, Wahl ML, Rauch C, Chiesi A, Pouyssegur J, Gatenby RA, Rivoltini L, Fais S (2010) Proton dynamics in cancer. J Transl Med 8:57. doi: 10.1186/1479-5876-8-57
-
(2010)
J Transl Med
, vol.8
, pp. 57
-
-
Huber, V.1
De Milito, A.2
Harguindey, S.3
Reshkin, S.J.4
Wahl, M.L.5
Rauch, C.6
Chiesi, A.7
Pouyssegur, J.8
Gatenby, R.A.9
Rivoltini, L.10
Fais, S.11
-
24
-
-
78649659788
-
PH control mechanisms of tumor survival and growth
-
Parks SK, Chiche J, Pouyssegur J (2011) pH control mechanisms of tumor survival and growth. J Cell Physiol 226(2):299-308. doi:10.1002/jcp.22400
-
(2011)
J Cell Physiol
, vol.226
, Issue.2
, pp. 299-308
-
-
Parks, S.K.1
Chiche, J.2
Pouyssegur, J.3
-
25
-
-
77955296520
-
Membrane-bound carbonic anhy-drases are key pH regulators controlling tumor growth and cell migration
-
Chiche J, Ilc K, Brahimi-Horn MC, Pouyssegur J (2010) Membrane-bound carbonic anhy-drases are key pH regulators controlling tumor growth and cell migration. Adv Enzyme Regul 50(1):20-33. doi:10.1016/j.advenzreg.2009.10.005
-
(2010)
Adv Enzyme Regul
, vol.50
, Issue.1
, pp. 20-33
-
-
Chiche, J.1
Ilc, K.2
Brahimi-Horn, M.C.3
Pouyssegur, J.4
-
26
-
-
44449125717
-
Cancer-associated, hypoxia-inducible carbonic anhydrase IX facilitates CO2 diffusion
-
Swietach P, Wigfield S, Supuran CT, Harris AL, Vaughan-Jones RD (2008) Cancer-associated, hypoxia-inducible carbonic anhydrase IX facilitates CO2 diffusion. BJU Int 4:22-24
-
(2008)
BJU Int
, vol.4
, pp. 22-24
-
-
Swietach, P.1
Wigfield, S.2
Supuran, C.T.3
Harris, A.L.4
Vaughan-Jones, R.D.5
-
27
-
-
84874104439
-
Characterization of carbonic anhydrase IX interactome reveals proteins assisting its nuclear localization in hypoxic cells
-
Buanne P, Renzone G, Monteleone F, Vitale M, Monti SM, Sandomenico A, Garbi C, Montanaro D, Accardo M, Troncone G, Zatovicova M, Csaderova L, Supuran CT, Pastorekova S, Scaloni A, De Simone G, Zambrano N (2013) Characterization of carbonic anhydrase IX interactome reveals proteins assisting its nuclear localization in hypoxic cells. J Proteome Res 12(1):282-292. doi:10.1021/pr300565w
-
(2013)
J Proteome Res
, vol.12
, Issue.1
, pp. 282-292
-
-
Buanne, P.1
Renzone, G.2
Monteleone, F.3
Vitale, M.4
Monti, S.M.5
Sandomenico, A.6
Garbi, C.7
Montanaro, D.8
Accardo, M.9
Troncone, G.10
Zatovicova, M.11
Csaderova, L.12
Supuran, C.T.13
Pastorekova, S.14
Scaloni, A.15
De Simone, G.16
Zambrano, N.17
-
28
-
-
0034671307
-
Hypoxia-inducible expression of tumor-associated carbonic anhydrases
-
Wykoff CC, Beasley NJ, Watson PH, Turner KJ, Pastorek J, Sibtain A, Wilson GD, Turley H, Talks KL, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL (2000) Hypoxia-inducible expression of tumor-associated carbonic anhydrases. Cancer Res 60(24):7075-7083
-
(2000)
Cancer Res
, vol.60
, Issue.24
, pp. 7075-7083
-
-
Wykoff, C.C.1
Beasley, N.J.2
Watson, P.H.3
Turner, K.J.4
Pastorek, J.5
Sibtain, A.6
Wilson, G.D.7
Turley, H.8
Talks, K.L.9
Maxwell, P.H.10
Pugh, C.W.11
Ratcliffe, P.J.12
Harris, A.L.13
-
29
-
-
0027210562
-
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia
-
Wang GL, Semenza GL (1993) General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci U S A 90(9):4304-4308
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, Issue.9
, pp. 4304-4308
-
-
Wang, G.L.1
Semenza, G.L.2
-
30
-
-
0027427588
-
Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia
-
Wang GL, Semenza GL (1993) Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia. J Biol Chem 268(29):21513-21518
-
(1993)
J Biol Chem
, vol.268
, Issue.29
, pp. 21513-21518
-
-
Wang, G.L.1
Semenza, G.L.2
-
31
-
-
62749124795
-
Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9: A one transcription factor (HIF-1) show?
-
Kaluz S, Kaluzova M, Liao SY, Lerman M, Stanbridge EJ (2009) Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9: a one transcription factor (HIF-1) show? Biochim Biophys Acta 1795(2):162-172. doi:10.1016/j.bbcan.2009.01.001
-
(2009)
Biochim Biophys Acta
, vol.1795
, Issue.2
, pp. 162-172
-
-
Kaluz, S.1
Kaluzova, M.2
Liao, S.Y.3
Lerman, M.4
Stanbridge, E.J.5
-
32
-
-
4644237401
-
Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors
-
Aprelikova O, Chandramouli GV, Wood M, Vasselli JR, Riss J, Maranchie JK, Linehan WM, Barrett JC (2004) Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors. J Cell Biochem 92(3):491-501. doi:10.1002/jcb.20067
-
(2004)
J Cell Biochem
, vol.92
, Issue.3
, pp. 491-501
-
-
Aprelikova, O.1
Chandramouli, G.V.2
Wood, M.3
Vasselli, J.R.4
Riss, J.5
Maranchie, J.K.6
Linehan, W.M.7
Barrett, J.C.8
-
33
-
-
77955284188
-
The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism
-
Zhang N, Fu Z, Linke S, Chicher J, Gorman JJ, Visk D, Haddad GG, Poellinger L, Peet DJ, Powell F, Johnson RS (2010) The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism. CellMetab 11(5):364-378. doi:10.1016/j.cmet.2010.03.001
-
(2010)
Cellmetab
, vol.11
, Issue.5
, pp. 364-378
-
-
Zhang, N.1
Fu, Z.2
Linke, S.3
Chicher, J.4
Gorman, J.J.5
Visk, D.6
Haddad, G.G.7
Poellinger, L.8
Peet, D.J.9
Powell, F.10
Johnson, R.S.11
-
34
-
-
0036469038
-
Asparagine hydroxy-lation of the HIF transactivation domain a hypoxic switch
-
Lando D, Peet DJ, Whelan DA, Gorman JJ, Whitelaw ML (2002) Asparagine hydroxy-lation of the HIF transactivation domain a hypoxic switch. Science 295(5556):858-861. doi: 10.1126/science.1068592
-
(2002)
Science
, vol.295
, Issue.5556
, pp. 858-861
-
-
Lando, D.1
Peet, D.J.2
Whelan, D.A.3
Gorman, J.J.4
Whitelaw, M.L.5
-
35
-
-
0032731194
-
Transcriptional regulation of the MN/CA 9 gene coding for the tumor-associated carbonic anhydrase IX. Identification and characterization of a proximal silencer element
-
Kaluz S, Kaluzova M, Opavsky R, Pastorekova S, Gibadulinova A, Dequiedt F, Kettmann R, Pastorek J (1999) Transcriptional regulation of the MN/CA 9 gene coding for the tumor-associated carbonic anhydrase IX. Identification and characterization of a proximal silencer element. J Biol Chem 274(46):32588-32595
-
(1999)
J Biol Chem
, vol.274
, Issue.46
, pp. 32588-32595
-
-
Kaluz, S.1
Kaluzova, M.2
Opavsky, R.3
Pastorekova, S.4
Gibadulinova, A.5
Dequiedt, F.6
Kettmann, R.7
Pastorek, J.8
-
36
-
-
0037374179
-
Expression of the hypoxia marker carbonic anhydrase IX is critically dependent on SP1 activity. Identification of a novel type of hypoxia-responsive enhancer
-
Kaluz S, Kaluzova M, Stanbridge EJ (2003) Expression of the hypoxia marker carbonic anhydrase IX is critically dependent on SP1 activity. Identification of a novel type of hypoxia-responsive enhancer. Cancer Res 63(5):917-922
-
(2003)
Cancer Res
, vol.63
, Issue.5
, pp. 917-922
-
-
Kaluz, S.1
Kaluzova, M.2
Stanbridge, E.J.3
-
37
-
-
0035503904
-
Characterization of the MN/CA 9 promoter proximal region: A role for specificity protein (SP) and activator protein 1 (AP1) factors
-
Kaluzova M, Pastorekova S, Svastova E, Pastorek J, Stanbridge EJ, Kaluz S (2001) Characterization of the MN/CA 9 promoter proximal region: a role for specificity protein (SP) and activator protein 1 (AP1) factors. Biochem J 359(Pt 3):669-677
-
(2001)
Biochem J
, vol.359
, pp. 669-677
-
-
Kaluzova, M.1
Pastorekova, S.2
Svastova, E.3
Pastorek, J.4
Stanbridge, E.J.5
Kaluz, S.6
-
38
-
-
77953276827
-
Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX
-
Hao Y, Li Y, Zhang J, Liu D, Liu F, Zhao Y, Shen T, Li F (2010) Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX. Nucleic Acids Res 38(9):2813-2824. doi:10.1093/nar/gkq006
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.9
, pp. 2813-2824
-
-
Hao, Y.1
Li, Y.2
Zhang, J.3
Liu, D.4
Liu, F.5
Zhao, Y.6
Shen, T.7
Li, F.8
-
39
-
-
0036682009
-
Lowered oxygen tension induces expression of the hypoxia marker MN/carbonic anhydrase IX in the absence of hypoxia-inducible factor 1 alpha stabilization: A role for phosphatidylinositol 3'-kinase
-
Kaluz S, Kaluzova M, Chrastina A, Olive PL, Pastorekova S, Pastorek J, Lerman MI, Stanbridge EJ (2002) Lowered oxygen tension induces expression of the hypoxia marker MN/carbonic anhydrase IX in the absence of hypoxia-inducible factor 1 alpha stabilization: a role for phosphatidylinositol 3'-kinase. Cancer Res 62(15):4469-4477
-
(2002)
Cancer Res
, vol.62
, Issue.15
, pp. 4469-4477
-
-
Kaluz, S.1
Kaluzova, M.2
Chrastina, A.3
Olive, P.L.4
Pastorekova, S.5
Pastorek, J.6
Lerman, M.I.7
Stanbridge, E.J.8
-
40
-
-
19544381887
-
MAPK pathway contributes to density- and hypoxia-induced expression of the tumor-associated carbonic anhydrase IX
-
Kopacek J, Barathova M, Dequiedt F, Sepelakova J, Kettmann R, Pastorek J, Pastorekova S (2005) MAPK pathway contributes to density- and hypoxia-induced expression of the tumor-associated carbonic anhydrase IX. Biochim Biophys Acta 1729(1):41-49. doi:10.1016/j.bbaexp.2005.03.003
-
(2005)
Biochim Biophys Acta
, vol.1729
, Issue.1
, pp. 41-49
-
-
Kopacek, J.1
Barathova, M.2
Dequiedt, F.3
Sepelakova, J.4
Kettmann, R.5
Pastorek, J.6
Pastorekova, S.7
-
41
-
-
71749105278
-
Intact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX
-
Hulikova A, Zatovicova M, Svastova E, Ditte P, Brasseur R, Kettmann R, Supuran CT, Kopacek J, Pastorek J, Pastorekova S (2009) Intact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX. FEBS Lett 583(22):3563-3568. doi:10.1016/j.febslet.2009.10.060
-
(2009)
FEBS Lett
, vol.583
, Issue.22
, pp. 3563-3568
-
-
Hulikova, A.1
Zatovicova, M.2
Svastova, E.3
Ditte, P.4
Brasseur, R.5
Kettmann, R.6
Supuran, C.T.7
Kopacek, J.8
Pastorek, J.9
Pastorekova, S.10
-
42
-
-
28244451574
-
The role of carbonic anhydrase IX overexpression in kidney cancer
-
Dorai T, Sawczuk IS, Pastorek J, Wiernik PH, Dutcher JP (2005) The role of carbonic anhydrase IX overexpression in kidney cancer. Eur J Cancer 41(18):2935-2947. doi:10.1016/j.ejca.2005.09.011
-
(2005)
Eur J Cancer
, vol.41
, Issue.18
, pp. 2935-2947
-
-
Dorai, T.1
Sawczuk, I.S.2
Pastorek, J.3
Wiernik, P.H.4
Dutcher, J.P.5
-
43
-
-
84255199558
-
Phosphorylation of carbonic anhydrase IX controls its ability to mediate extracellular acidification in hypoxic tumors
-
Ditte P, Dequiedt F, Svastova E, Hulikova A, Ohradanova-Repic A, Zatovicova M, Csaderova L, Kopacek J, Supuran CT, Pastorekova S, Pastorek J (2011) Phosphorylation of carbonic anhydrase IX controls its ability to mediate extracellular acidification in hypoxic tumors. Cancer Res 71(24):7558-7567. doi:10.1158/0008-5472.can-11-2520
-
(2011)
Cancer Res
, vol.71
, Issue.24
, pp. 7558-7567
-
-
Ditte, P.1
Dequiedt, F.2
Svastova, E.3
Hulikova, A.4
Ohradanova-Repic, A.5
Zatovicova, M.6
Csaderova, L.7
Kopacek, J.8
Supuran, C.T.9
Pastorekova, S.10
Pastorek, J.11
-
44
-
-
0141887319
-
Soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients
-
Zavada J, Zavadova Z, Zat'ovicova M, Hyrsl L, Kawaciuk I (2003) Soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients. Br J Cancer 89(6):1067-1071. doi:10.1038/sj.bjc.6601264
-
(2003)
Br J Cancer
, vol.89
, Issue.6
, pp. 1067-1071
-
-
Zavada, J.1
Zavadova, Z.2
Zat'ovicova, M.3
Hyrsl, L.4
Kawaciuk, I.5
-
45
-
-
27944500753
-
Ectodomain shedding of the hypoxia-induced carbonic anhydrase IX is a metalloprotease-dependent process regulated by TACE/ADAM17
-
Zatovicova M, Sedlakova O, Svastova E, Ohradanova A, Ciampor F, Arribas J, Pastorek J, Pastorekova S (2005) Ectodomain shedding of the hypoxia-induced carbonic anhydrase IX is a metalloprotease-dependent process regulated by TACE/ADAM17. Br J Cancer 93(11):1267-1276. doi:10.1038/sj.bjc.6602861
-
(2005)
Br J Cancer
, vol.93
, Issue.11
, pp. 1267-1276
-
-
Zatovicova, M.1
Sedlakova, O.2
Svastova, E.3
Ohradanova, A.4
Ciampor, F.5
Arribas, J.6
Pastorek, J.7
Pastorekova, S.8
-
46
-
-
0027981949
-
Identification of the MN antigen as a diagnostic biomarker of cervical intraepithelial squamous and glandular neoplasia and cervical carcinomas
-
Liao SY, Brewer C, Zavada J, Pastorek J, Pastorekova S, Manetta A, Berman ML, DiSaia PJ, Stanbridge EJ (1994) Identification of the MN antigen as a diagnostic biomarker of cervical intraepithelial squamous and glandular neoplasia and cervical carcinomas. Am J Pathol 145(3):598-609
-
(1994)
Am J Pathol
, vol.145
, Issue.3
, pp. 598-609
-
-
Liao, S.Y.1
Brewer, C.2
Zavada, J.3
Pastorek, J.4
Pastorekova, S.5
Manetta, A.6
Berman, M.L.7
Disaia, P.J.8
Stanbridge, E.J.9
-
47
-
-
0031040821
-
Carbonic anhydrase IX, MN/CA IX: Analysis of stomach complementary DNA sequence and expression in human and rat alimentary tracts
-
Pastorekova S, Parkkila S, Parkkila AK, Opavsky R, Zelnik V, Saarnio J, Pastorek J (1997) Carbonic anhydrase IX, MN/CA IX: analysis of stomach complementary DNA sequence and expression in human and rat alimentary tracts. Gastroenterology 112(2):398-408
-
(1997)
Gastroenterology
, vol.112
, Issue.2
, pp. 398-408
-
-
Pastorekova, S.1
Parkkila, S.2
Parkkila, A.K.3
Opavsky, R.4
Zelnik, V.5
Saarnio, J.6
Pastorek, J.7
-
48
-
-
36048987954
-
Carbonic anhydrase IX is not an independent predictor of outcome for patients with clear cell renal cell carcinoma
-
Leibovich BC, Sheinin Y, Lohse CM, Thompson RH, Cheville JC, Zavada J, Kwon ED (2007) Carbonic anhydrase IX is not an independent predictor of outcome for patients with clear cell renal cell carcinoma. J Clin Oncol 25(30):4757-4764. doi:10.1200/jco.2007.12.1087
-
(2007)
J Clin Oncol
, vol.25
, Issue.30
, pp. 4757-4764
-
-
Leibovich, B.C.1
Sheinin, Y.2
Lohse, C.M.3
Thompson, R.H.4
Cheville, J.C.5
Zavada, J.6
Kwon, E.D.7
-
49
-
-
0035107383
-
Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer
-
Ivanov S, Liao SY, Ivanova A, Danilkovitch-Miagkova A, Tarasova N, Weirich G, Merrill MJ, Proescholdt MA, Oldfield EH, Lee J, Zavada J, Waheed A, Sly W, Lerman MI, Stanbridge EJ (2001) Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer. Am J Pathol 158(3):905-919. doi:10.1016/s0002-9440(10)64038-2
-
(2001)
Am J Pathol
, vol.158
, Issue.3
, pp. 905-919
-
-
Ivanov, S.1
Liao, S.Y.2
Ivanova, A.3
Danilkovitch-Miagkova, A.4
Tarasova, N.5
Weirich, G.6
Merrill, M.J.7
Proescholdt, M.A.8
Oldfield, E.H.9
Lee, J.10
Zavada, J.11
Waheed, A.12
Sly, W.13
Lerman, M.I.14
Stanbridge, E.J.15
-
50
-
-
78649636616
-
Carbonic anhydrase 9 in clear cell renal cell carcinoma: A marker for diagnosis, prognosis and treatment
-
Tostain J, Li G, Gentil-Perret A, Gigante M (2010) Carbonic anhydrase 9 in clear cell renal cell carcinoma: a marker for diagnosis, prognosis and treatment. Eur J Cancer 46(18):3141-3148. doi:10.1016/j.ejca.2010.07.020
-
(2010)
Eur J Cancer
, vol.46
, Issue.18
, pp. 3141-3148
-
-
Tostain, J.1
Li, G.2
Gentil-Perret, A.3
Gigante, M.4
-
51
-
-
0022502868
-
Monoclonal antibody G250 recognizes a determinant present in renal-cell carcinoma and absent from normal kidney
-
Oosterwijk E, Ruiter DJ, Hoedemaeker PJ, Pauwels EK, Jonas U, Zwartendijk J, Warnaar SO (1986) Monoclonal antibody G250 recognizes a determinant present in renal-cell carcinoma and absent from normal kidney. Int J Cancer 38(4):489-494
-
(1986)
Int J Cancer
, vol.38
, Issue.4
, pp. 489-494
-
-
Oosterwijk, E.1
Ruiter, D.J.2
Hoedemaeker, P.J.3
Pauwels, E.K.4
Jonas, U.5
Zwartendijk, J.6
Warnaar, S.O.7
-
52
-
-
44449089520
-
Carbonic anhydrase IX: Historical and future perspectives
-
Oosterwijk E (2008) Carbonic anhydrase IX: historical and future perspectives. BJU Int 101(Suppl 4):2-7. doi:10.1111/j.1464-410X.2008.07641.x
-
(2008)
BJU Int
, vol.101
, pp. 2-7
-
-
Oosterwijk, E.1
-
53
-
-
78649676646
-
Carbonic anhydrase IX expression in renal neoplasms: Correlation with tumor type and grade
-
Genega EM, Ghebremichael M, Najarian R, Fu Y, Wang Y, Argani P, Grisanzio C, Signoretti S (2010) Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade. Am J Clin Pathol 134(6):873-879. doi:10.1309/ajcpppr57hnjmslz
-
(2010)
Am J Clin Pathol
, vol.134
, Issue.6
, pp. 873-879
-
-
Genega, E.M.1
Ghebremichael, M.2
Najarian, R.3
Fu, Y.4
Wang, Y.5
Argani, P.6
Grisanzio, C.7
Signoretti, S.8
-
54
-
-
75749122186
-
Prognostic relevance of carbonic anhydrase-IX in high-risk, early-stage cervical cancer: A gynecologic oncology group study
-
Liao SY, Darcy KM, Randall LM, Tian C, Monk BJ, Burger RA, Fruehauf JP, Peters WA, Stock RJ, Stanbridge EJ (2010) Prognostic relevance of carbonic anhydrase-IX in high-risk, early-stage cervical cancer: a gynecologic oncology group study. Gynecol Oncol 116(3):452-458. doi:10.1016/j.ygyno.2009.10.062
-
(2010)
Gynecol Oncol
, vol.116
, Issue.3
, pp. 452-458
-
-
Liao, S.Y.1
Darcy, K.M.2
Randall, L.M.3
Tian, C.4
Monk, B.J.5
Burger, R.A.6
Fruehauf, J.P.7
Peters, W.A.8
Stock, R.J.9
Stanbridge, E.J.10
-
55
-
-
62549099960
-
Expression of carbonic anhydrase IX suggests poor outcome in rectal cancer
-
Korkeila E, Talvinen K, Jaakkola PM, Minn H, Syrjanen K, Sundstrom J, Pyrhonen S (2009) Expression of carbonic anhydrase IX suggests poor outcome in rectal cancer. Br J Cancer 100(6):874-880. doi:10.1038/sj.bjc.6604949
-
(2009)
Br J Cancer
, vol.100
, Issue.6
, pp. 874-880
-
-
Korkeila, E.1
Talvinen, K.2
Jaakkola, P.M.3
Minn, H.4
Syrjanen, K.5
Sundstrom, J.6
Pyrhonen, S.7
-
56
-
-
33846211525
-
Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer
-
Hussain SA, Ganesan R, Reynolds G, Gross L, Stevens A, Pastorek J, Murray PG, Perunovic B, Anwar MS, Billingham L, James ND, Spooner D, Poole CJ, Rea DW, Palmer DH (2007) Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer. Br J Cancer 96(1):104-109. doi:10.1038/sj.bjc.6603530
-
(2007)
Br J Cancer
, vol.96
, Issue.1
, pp. 104-109
-
-
Hussain, S.A.1
Ganesan, R.2
Reynolds, G.3
Gross, L.4
Stevens, A.5
Pastorek, J.6
Murray, P.G.7
Perunovic, B.8
Anwar, M.S.9
Billingham, L.10
James, N.D.11
Spooner, D.12
Poole, C.J.13
Rea, D.W.14
Palmer, D.H.15
-
57
-
-
33644756432
-
Quantitative analysis of carbonic anhy-drase IX mRNA in human non-small cell lung cancer
-
Simi L, Venturini G, Malentacchi F, Gelmini S, Andreani M, Janni A, Pastorekova S, Supuran CT, Pazzagli M, Orlando C (2006) Quantitative analysis of carbonic anhy-drase IX mRNA in human non-small cell lung cancer. Lung Cancer 52(1):59-66. doi:10.1016/j.lungcan.2005.11.017
-
(2006)
Lung Cancer
, vol.52
, Issue.1
, pp. 59-66
-
-
Simi, L.1
Venturini, G.2
Malentacchi, F.3
Gelmini, S.4
Reani, M.5
Janni, A.6
Pastorekova, S.7
Supuran, C.T.8
Pazzagli, M.9
Orlando, C.10
-
58
-
-
39549089089
-
Carbonic anhydrase IX in oligodendroglial brain tumors
-
Jarvela S, Parkkila S, Bragge H, Kahkonen M, Parkkila AK, Soini Y, Pastorekova S, Pastorek J, Haapasalo H (2008) Carbonic anhydrase IX in oligodendroglial brain tumors. BMC Cancer 8:1. doi:10.1186/1471-2407-8-1
-
(2008)
BMC Cancer
, vol.8
, pp. 1
-
-
Jarvela, S.1
Parkkila, S.2
Bragge, H.3
Kahkonen, M.4
Parkkila, A.K.5
Soini, Y.6
Pastorekova, S.7
Pastorek, J.8
Haapasalo, H.9
-
59
-
-
0037314709
-
Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: Implications for prognosis and therapy
-
Bui MH, Seligson D, Han KR, Pantuck AJ, Dorey FJ, Huang Y, Horvath S, Leibovich BC, Chopra S, Liao SY, Stanbridge E, Lerman MI, Palotie A, Figlin RA, Belldegrun AS (2003) Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy. Clin Cancer Res 9(2):802-811
-
(2003)
Clin Cancer Res
, vol.9
, Issue.2
, pp. 802-811
-
-
Bui, M.H.1
Seligson, D.2
Han, K.R.3
Pantuck, A.J.4
Dorey, F.J.5
Huang, Y.6
Horvath, S.7
Leibovich, B.C.8
Chopra, S.9
Liao, S.Y.10
Stanbridge, E.11
Lerman, M.I.12
Palotie, A.13
Figlin, R.A.14
Belldegrun, A.S.15
-
60
-
-
0032788570
-
Acidic environment causes apoptosis by increasing caspase activity
-
Park HJ, Lyons JC, Ohtsubo T, Song CW (1999) Acidic environment causes apoptosis by increasing caspase activity. Br J Cancer 80(12):1892-1897. doi:10.1038/sj.bjc.6690617
-
(1999)
Br J Cancer
, vol.80
, Issue.12
, pp. 1892-1897
-
-
Park, H.J.1
Lyons, J.C.2
Ohtsubo, T.3
Song, C.W.4
-
61
-
-
33744942376
-
Acid-mediated tumor invasion: Amultidisciplinary study
-
Gatenby RA, Gawlinski ET, Gmitro AF, Kaylor B, Gillies RJ (2006) Acid-mediated tumor invasion: amultidisciplinary study. Cancer Res 66(10):5216-5223. doi:10.1158/0008-5472.can-05-4193
-
(2006)
Cancer Res
, vol.66
, Issue.10
, pp. 5216-5223
-
-
Gatenby, R.A.1
Gawlinski, E.T.2
Gmitro, A.F.3
Kaylor, B.4
Gillies, R.J.5
-
62
-
-
0035881307
-
Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo
-
Fukumura D, Xu L, Chen Y, Gohongi T, Seed B, Jain RK (2001) Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo. CancerRes 61(16):6020-6024
-
(2001)
Cancerres
, vol.61
, Issue.16
, pp. 6020-6024
-
-
Fukumura, D.1
Xu, L.2
Chen, Y.3
Gohongi, T.4
Seed, B.5
Jain, R.K.6
-
63
-
-
44449091556
-
Molecular mechanisms of carbonic anhydrase IX-mediated pH regulation under hypoxia
-
Pastorekova S, Ratcliffe PJ, Pastorek J (2008) Molecular mechanisms of carbonic anhydrase IX-mediated pH regulation under hypoxia. BJU Int 101(Suppl 4):8-15. doi:10.1111/j.1464-410X.2008.07642.x
-
(2008)
BJU Int
, vol.101
, pp. 8-15
-
-
Pastorekova, S.1
Ratcliffe, P.J.2
Pastorek, J.3
-
64
-
-
0031748828
-
The contribution of lactic acid to acidification of tumours: Studies of variant cells lacking lactate dehydrogenase
-
Yamagata M, Hasuda K, Stamato T, Tannock IF (1998) The contribution of lactic acid to acidification of tumours: studies of variant cells lacking lactate dehydrogenase. Br J Cancer 77(11):1726-1731
-
(1998)
Br J Cancer
, vol.77
, Issue.11
, pp. 1726-1731
-
-
Yamagata, M.1
Hasuda, K.2
Stamato, T.3
Tannock, I.F.4
-
65
-
-
34447547148
-
Regulation of tumor pH and the role of carbonic anhydrase 9
-
Swietach P, Vaughan-Jones RD, Harris AL (2007) Regulation of tumor pH and the role of carbonic anhydrase 9. Cancer Metastasis Rev 26(2):299-310. doi:10.1007/s10555-007-9064-0
-
(2007)
Cancer Metastasis Rev
, vol.26
, Issue.2
, pp. 299-310
-
-
Swietach, P.1
Vaughan-Jones, R.D.2
Harris, A.L.3
-
66
-
-
34547793020
-
Interactions of transmembrane carbonic anhydrase, CAIX, with bicarbonate transporters
-
Morgan PE, Pastorekova S, Stuart-Tilley AK, Alper SL, Casey JR (2007) Interactions of transmembrane carbonic anhydrase, CAIX, with bicarbonate transporters. Am J Physiol 293(2):C738-C748. doi:10.1152/ajpcell.00157.2007
-
(2007)
Am J Physiol
, vol.293
, Issue.2
, pp. 738-748
-
-
Morgan, P.E.1
Pastorekova, S.2
Stuart-Tilley, A.K.3
Alper, S.L.4
Casey, J.R.5
-
67
-
-
84856237720
-
Carbonic anhydrase IX interacts with bicarbonate transporters in lamellipodia and increases cell migration via its catalytic domain
-
Svastova E, Witarski W, Csaderova L, Kosik I, Skvarkova L, Hulikova A, Zatovicova M, Barathova M, Kopacek J, Pastorek J, Pastorekova S (2012) Carbonic anhydrase IX interacts with bicarbonate transporters in lamellipodia and increases cell migration via its catalytic domain. J Biol Chem 287(5):3392-3402. doi:10.1074/jbc.M111.286062
-
(2012)
J Biol Chem
, vol.287
, Issue.5
, pp. 3392-3402
-
-
Svastova, E.1
Witarski, W.2
Csaderova, L.3
Kosik, I.4
Skvarkova, L.5
Hulikova, A.6
Zatovicova, M.7
Barathova, M.8
Kopacek, J.9
Pastorek, J.10
Pastorekova, S.11
-
68
-
-
24944481656
-
The role of pH dynamics and the NaC/HC antiporter in the etiopathogenesis and treatment of cancer. Two faces of the same coin-one single nature
-
Harguindey S, Orive G, Luis Pedraz J, Paradiso A, Reshkin SJ (2005) The role of pH dynamics and the NaC/HC antiporter in the etiopathogenesis and treatment of cancer. Two faces of the same coin-one single nature. Biochim Biophys Acta 1756(1):1-24. doi:10.1016/j.bbcan.2005.06.004
-
(2005)
Biochim Biophys Acta
, vol.1756
, Issue.1
, pp. 1-24
-
-
Harguindey, S.1
Orive, G.2
Luis Pedraz, J.3
Paradiso, A.4
Reshkin, S.J.5
-
69
-
-
4544279148
-
Plasmalemmal vacuolar-type HC-ATPase in cancer biology
-
Sennoune SR, Luo D, Martinez-Zaguilan R (2004) Plasmalemmal vacuolar-type HC-ATPase in cancer biology. Cell Biochem Biophys 40(2):185-206.doi:10.1385/cbb:40:2:185
-
(2004)
Cell Biochem Biophys
, vol.40
, Issue.2
, pp. 185-206
-
-
Sennoune, S.R.1
Luo, D.2
Martinez-Zaguilan, R.3
-
70
-
-
1242340302
-
The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond
-
Halestrap AP, Meredith D (2004) The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. Pflugers Archiv European J Physiol 447(5):619-628. doi:10.1007/s00424-003-1067-2
-
(2004)
Pflugers Archiv European J Physiol
, vol.447
, Issue.5
, pp. 619-628
-
-
Halestrap, A.P.1
Meredith, D.2
-
71
-
-
0038431219
-
Molecular mechanisms of tumor metastasis and angiogenesis
-
Bohle AS, Kalthoff H (1999) Molecular mechanisms of tumor metastasis and angiogenesis. Langenbecks Arch Surg 384(2):133-140
-
(1999)
Langenbecks Arch Surg
, vol.384
, Issue.2
, pp. 133-140
-
-
Bohle, A.S.1
Kalthoff, H.2
-
72
-
-
84869752511
-
Hypoxia activated EGFR signaling induces epithelial to mesenchymal transition (EMT)
-
Misra A, Pandey C, Sze SK, Thanabalu T (2012) Hypoxia activated EGFR signaling induces epithelial to mesenchymal transition (EMT). PLoS One 7(11):e49766. doi:10.1371/journal.pone.0049766
-
(2012)
Plos One
, vol.7
, Issue.11
, pp. 49766
-
-
Misra, A.1
Pandey, C.2
Sze, S.K.3
Thanabalu, T.4
-
73
-
-
0028618307
-
Pericellular pH affects distribution and secretion of cathepsin B in malignant cells
-
Rozhin J, Sameni M, Ziegler G, Sloane BF (1994) Pericellular pH affects distribution and secretion of cathepsin B in malignant cells. Cancer Res 54(24):6517-6525
-
(1994)
Cancer Res
, vol.54
, Issue.24
, pp. 6517-6525
-
-
Rozhin, J.1
Sameni, M.2
Ziegler, G.3
Sloane, B.F.4
-
74
-
-
44449089860
-
Acid treatment of melanoma cells selects for invasive phenotypes
-
Moellering RE, Black KC, Krishnamurty C, Baggett BK, Stafford P, Rain M, Gatenby RA, Gillies RJ (2008) Acid treatment of melanoma cells selects for invasive phenotypes. Clin Exp Metastasis 25(4):411-425. doi:10.1007/s10585-008-9145-7
-
(2008)
Clin Exp Metastasis
, vol.25
, Issue.4
, pp. 411-425
-
-
Moellering, R.E.1
Black, K.C.2
Krishnamurty, C.3
Baggett, B.K.4
Stafford, P.5
Rain, M.6
Gatenby, R.A.7
Gillies, R.J.8
-
75
-
-
0345791482
-
Extracellular acidification alters lysosomal trafficking in human breast cancer cells
-
Glunde K, Guggino SE, Solaiyappan M, Pathak AP, Ichikawa Y, Bhujwalla ZM (2003) Extracellular acidification alters lysosomal trafficking in human breast cancer cells. Neoplasia 5(6):533-545
-
(2003)
Neoplasia
, vol.5
, Issue.6
, pp. 533-545
-
-
Glunde, K.1
Guggino, S.E.2
Solaiyappan, M.3
Pathak, A.P.4
Ichikawa, Y.5
Bhujwalla, Z.M.6
-
76
-
-
0032786530
-
Regulation of E-cadherin: Does hypoxia initiate the metastatic cascade?
-
Beavon IR (1999) Regulation of E-cadherin: does hypoxia initiate the metastatic cascade? Mol Pathol 52(4):179-188
-
(1999)
Mol Pathol
, vol.52
, Issue.4
, pp. 179-188
-
-
Beavon, I.R.1
-
77
-
-
0028964341
-
Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1)
-
Berx G, Staes K, van Hengel J, Molemans F, Bussemakers MJ, van Bokhoven A, van Roy F (1995) Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1). Genomics 26(2):281-289
-
(1995)
Genomics
, vol.26
, Issue.2
, pp. 281-289
-
-
Berx, G.1
Staes, K.2
Van Hengel, J.3
Molemans, F.4
Bussemakers, M.J.5
Van Bokhoven, A.6
Van Roy, F.7
-
78
-
-
80051901366
-
The role of the cell adhesion molecules (Integrins/cadherins) in prostate cancer
-
Drivalos A, Papatsoris AG, Chrisofos M, Efstathiou E, Dimopoulos MA (2011) The role of the cell adhesion molecules (integrins/cadherins) in prostate cancer. Int Braz J Urol 37(3):302-306
-
(2011)
Int Braz J Urol
, vol.37
, Issue.3
, pp. 302-306
-
-
Drivalos, A.1
Papatsoris, A.G.2
Chrisofos, M.3
Efstathiou, E.4
Dimopoulos, M.A.5
-
79
-
-
77954374568
-
The expression of E-cadherin-catenin complex in patients with advanced gastric cancer: Role in formation of metastasis
-
Czyzewska J, Guzinska-Ustymowicz K, Ustymowicz M, Pryczynicz A, Kemona A (2010) The expression of E-cadherin-catenin complex in patients with advanced gastric cancer: role in formation of metastasis. Folia Histochem Cytobiol 48(1):37-45. doi:10.2478/v10042-010-0017-z
-
(2010)
Folia Histochem Cytobiol
, vol.48
, Issue.1
, pp. 37-45
-
-
Czyzewska, J.1
Guzinska-Ustymowicz, K.2
Ustymowicz, M.3
Pryczynicz, A.4
Kemona, A.5
-
80
-
-
33751252276
-
Cancer metastasis: Building a framework
-
Gupta GP, Massague J (2006) Cancer metastasis: building a framework. Cell 127(4):679-695. doi:10.1016/j.cell.2006.11.001
-
(2006)
Cell
, vol.127
, Issue.4
, pp. 679-695
-
-
Gupta, G.P.1
Massague, J.2
-
81
-
-
68149105927
-
Protons make tumor cells move like clockwork
-
Stock C, Schwab A (2009) Protons make tumor cells move like clockwork. Pflugers Arch 458(5):981-992. doi:10.1007/s00424-009-0677-8
-
(2009)
Pflugers Arch
, vol.458
, Issue.5
, pp. 981-992
-
-
Stock, C.1
Schwab, A.2
-
82
-
-
79952145914
-
Intracellular pH gradients in migrating cells
-
Martin C, Pedersen SF, Schwab A, Stock C (2011) Intracellular pH gradients in migrating cells. Am J Physiol 300(3):C490-C495. doi:10.1152/ajpcell.00280.2010
-
(2011)
Am J Physiol
, vol.300
, Issue.3
, pp. 490-495
-
-
Martin, C.1
Pedersen, S.F.2
Schwab, A.3
Stock, C.4
-
83
-
-
36649014657
-
PH dependence of melanoma cell migration: Protons extruded by NHE1 dominate protons of the bulk solution
-
Stuwe L, Muller M, Fabian A, Waning J, Mally S, Noel J, Schwab A, Stock C (2007) pH dependence of melanoma cell migration: protons extruded by NHE1 dominate protons of the bulk solution. J Physiol 585(Pt 2):351-360. doi:10.1113/jphysiol.2007.145185
-
(2007)
J Physiol
, vol.585
, pp. 351-360
-
-
Stuwe, L.1
Muller, M.2
Fabian, A.3
Waning, J.4
Mally, S.5
Noel, J.6
Schwab, A.7
Stock, C.8
-
84
-
-
23844449323
-
Migration of human melanoma cells depends on extracellular pH and NaC/HC exchange
-
Stock C, Gassner B, Hauck CR, Arnold H, Mally S, Eble JA, Dieterich P, Schwab A (2005) Migration of human melanoma cells depends on extracellular pH and NaC/HC exchange. J Physiol 567(Pt 1):225-238. doi:10.1113/jphysiol.2005.088344
-
(2005)
J Physiol
, vol.567
, pp. 225-238
-
-
Stock, C.1
Gassner, B.2
Hauck, C.R.3
Arnold, H.4
Mally, S.5
Eble, J.A.6
Dieterich, P.7
Schwab, A.8
-
85
-
-
65549095446
-
Spatial distribution of protein kinase A activity during cell migration is mediated by A-kinase anchoring protein AKAP Lbc
-
Paulucci-Holthauzen AA, Vergara LA, Bellot LJ, Canton D, Scott JD, O'Connor KL (2009) Spatial distribution of protein kinase A activity during cell migration is mediated by A-kinase anchoring protein AKAP Lbc. J Biol Chem 284(9):5956-5967. doi:10.1074/jbc.M805606200
-
(2009)
J Biol Chem
, vol.284
, Issue.9
, pp. 5956-5967
-
-
Paulucci-Holthauzen, A.A.1
Vergara, L.A.2
Bellot, L.J.3
Canton, D.4
Scott, J.D.5
O'connor, K.L.6
-
86
-
-
0142121458
-
Carbonic anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via interaction with beta-catenin
-
Svastova E, Zilka N, Zat'ovicova M, Gibadulinova A, Ciampor F, Pastorek J, Pastorekova S (2003) Carbonic anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via interaction with beta-catenin. Exp Cell Res 290(2):332-345
-
(2003)
Exp Cell Res
, vol.290
, Issue.2
, pp. 332-345
-
-
Svastova, E.1
Zilka, N.2
Zat'ovicova, M.3
Gibadulinova, A.4
Ciampor, F.5
Pastorek, J.6
Pastorekova, S.7
-
87
-
-
84860003307
-
Dickkopf-1 (DKK-1) interrupts FAK/PI3K/mTOR pathway by interaction of carbonic anhydrase IX (CA9) in tumorigenesis
-
Kim BR, Shin HJ, Kim JY, Byun HJ, Lee JH, Sung YK, Rho SB (2012) Dickkopf-1 (DKK-1) interrupts FAK/PI3K/mTOR pathway by interaction of carbonic anhydrase IX (CA9) in tumorigenesis. Cell Signal 24(7):1406-1413. doi:10.1016/j.cellsig.2012.03.002
-
(2012)
Cell Signal
, vol.24
, Issue.7
, pp. 1406-1413
-
-
Kim, B.R.1
Shin, H.J.2
Kim, J.Y.3
Byun, H.J.4
Lee, J.H.5
Sung, Y.K.6
Rho, S.B.7
-
88
-
-
79953138420
-
Carbonic anhydrase IX (CA9) modulates tumor-associated cell migration and invasion
-
Shin HJ, Rho SB, Jung DC, Han IO, Oh ES, Kim JY (2011) Carbonic anhydrase IX (CA9) modulates tumor-associated cell migration and invasion. J Cell Sci 124(Pt 7):1077-1087. doi:10.1242/jcs.072207
-
(2011)
J Cell Sci
, vol.124
, pp. 1077-1087
-
-
Shin, H.J.1
Rho, S.B.2
Jung, D.C.3
Han, I.O.4
Oh, E.S.5
Kim, J.Y.6
-
89
-
-
0034009497
-
Carbonic anhydrase inhibitor suppresses invasion of renal cancer cells in vitro
-
Parkkila S, Rajaniemi H, Parkkila AK, Kivela J, Waheed A, Pastorekova S, Pastorek J, Sly WS (2000) Carbonic anhydrase inhibitor suppresses invasion of renal cancer cells in vitro. Proc Natl Acad Sci U S A 97(5):2220-2224. doi:10.1073/pnas.040554897
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.5
, pp. 2220-2224
-
-
Parkkila, S.1
Rajaniemi, H.2
Parkkila, A.K.3
Kivela, J.4
Waheed, A.5
Pastorekova, S.6
Pastorek, J.7
Sly, W.S.8
-
90
-
-
84867818496
-
Inhibition of carbonic anhydrase IX as a novel anticancer mechanism
-
Supuran CT (2012) Inhibition of carbonic anhydrase IX as a novel anticancer mechanism. World Journal of Clinical Oncology 3(7):98-103. doi:10.5306/wjco.v3.i7.98
-
(2012)
World Journal of Clinical Oncology
, vol.3
, Issue.7
, pp. 98-103
-
-
Supuran, C.T.1
-
91
-
-
84858288806
-
Novel coumarins and 2-thioxo-coumarins as inhibitors of the tumor-associated carbonic anhydrases IX and XII
-
Carta F, Maresca A, Scozzafava A, Supuran CT (2012) Novel coumarins and 2-thioxo-coumarins as inhibitors of the tumor-associated carbonic anhydrases IX and XII. Bioorg Med Chem 20(7):2266-2273. doi:10.1016/j.bmc.2012.02.014
-
(2012)
Bioorg Med Chem
, vol.20
, Issue.7
, pp. 2266-2273
-
-
Carta, F.1
Maresca, A.2
Scozzafava, A.3
Supuran, C.T.4
-
92
-
-
0027463723
-
Carbonic anhydrase inhibitors. Part 11. Coordination compounds of heterocyclic sulfonamides with lanthanides are potent inhibitors of isozymes I and II
-
Supuran CT, Manole G, Andruh M (1993) Carbonic anhydrase inhibitors. Part 11. Coordination compounds of heterocyclic sulfonamides with lanthanides are potent inhibitors of isozymes I and II. J Inorg Biochem 49(2):97-103
-
(1993)
J Inorg Biochem
, vol.49
, Issue.2
, pp. 97-103
-
-
Supuran, C.T.1
Manole, G.2
Ruh, M.3
-
93
-
-
79954591401
-
Correlation of in vivo and in vitro measures of carbonic anhydrase IX antigen expression in renal masses using antibody 124I-cG250
-
Pryma DA, O'Donoghue JA, Humm JL, Jungbluth AA, Old LJ, Larson SM, Divgi CR (2011) Correlation of in vivo and in vitro measures of carbonic anhydrase IX antigen expression in renal masses using antibody 124I-cG250. J Nucl Med 52(4):535-540. doi: 10.2967/jnumed.110.083295
-
(2011)
J Nucl Med
, vol.52
, Issue.4
, pp. 535-540
-
-
Pryma, D.A.1
O'donoghue, J.A.2
Humm, J.L.3
Jungbluth, A.A.4
Old, L.J.5
Larson, S.M.6
Divgi, C.R.7
-
94
-
-
68749119336
-
Human monoclonal antibodies targeting carbonic anhydrase IX for the molecular imaging of hypoxic regions in solid tumours
-
Ahlskog JK, Schliemann C, Marlind J, Qureshi U, Ammar A, Pedley RB, Neri D (2009) Human monoclonal antibodies targeting carbonic anhydrase IX for the molecular imaging of hypoxic regions in solid tumours. Br J Cancer 101(4):645-657. doi:10.1038/sj.bjc.6605200
-
(2009)
Br J Cancer
, vol.101
, Issue.4
, pp. 645-657
-
-
Ahlskog, J.K.1
Schliemann, C.2
Marlind, J.3
Qureshi, U.4
Ammar, A.5
Pedley, R.B.6
Neri, D.7
-
95
-
-
78649813619
-
Carbonic anhydrase IX as an anticancer therapy target: Preclinical evaluation of internalizing monoclonal antibody directed to catalytic domain
-
Zatovicova M, Jelenska L, Hulikova A, Csaderova L, Ditte Z, Ditte P, Goliasova T, Pastorek J, Pastorekova S (2010) Carbonic anhydrase IX as an anticancer therapy target: preclinical evaluation of internalizing monoclonal antibody directed to catalytic domain. Curr Pharm Des 16(29):3255-3263
-
(2010)
Curr Pharm Des
, vol.16
, Issue.29
, pp. 3255-3263
-
-
Zatovicova, M.1
Jelenska, L.2
Hulikova, A.3
Csaderova, L.4
Ditte, Z.5
Ditte, P.6
Goliasova, T.7
Pastorek, J.8
Pastorekova, S.9
-
96
-
-
77949716901
-
Unique biological properties of catalytic domain directed human anti-CAIX antibodies discovered through phage-display technology
-
Xu C, Lo A, Yammanuru A, Tallarico AS, Brady K, Murakami A, Barteneva N, Zhu Q, Marasco WA (2010) Unique biological properties of catalytic domain directed human anti-CAIX antibodies discovered through phage-display technology. PLoS One 5(3):e9625. doi: 10.1371/journal.pone.0009625
-
(2010)
Plos One
, vol.5
, Issue.3
, pp. 9625
-
-
Xu, C.1
Lo, A.2
Yammanuru, A.3
Tallarico, A.S.4
Brady, K.5
Murakami, A.6
Barteneva, N.7
Zhu, Q.8
Marasco, W.A.9
-
97
-
-
79952488307
-
Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX
-
Murri-Plesko MT, Hulikova A, Oosterwijk E, Scott AM, Zortea A, Harris AL, Ritter G, Old L, Bauer S, Swietach P, Renner C (2011) Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX. Eur J Pharmacol 657(1-3):173-183. doi:10.1016/j.ejphar.2011.01.063
-
(2011)
Eur J Pharmacol
, vol.657
, Issue.1-3
, pp. 173-183
-
-
Murri-Plesko, M.T.1
Hulikova, A.2
Oosterwijk, E.3
Scott, A.M.4
Zortea, A.5
Harris, A.L.6
Ritter, G.7
Old, L.8
Bauer, S.9
Swietach, P.10
Renner, C.11
-
98
-
-
78751650361
-
A clinical phase I/II trial with the monoclonal antibody cG250 (RENCAREX®) and interferon-alpha-2a in metastatic renal cell carcinoma patients
-
Siebels M, Rohrmann K, Oberneder R, Stahler M, Haseke N, Beck J, Hofmann R, Kindler M, Kloepfer P, Stief C (2011) A clinical phase I/II trial with the monoclonal antibody cG250 (RENCAREX®) and interferon-alpha-2a in metastatic renal cell carcinoma patients. World J Urol 29(1):121-126. doi:10.1007/s00345-010-0570-2
-
(2011)
World J Urol
, vol.29
, Issue.1
, pp. 121-126
-
-
Siebels, M.1
Rohrmann, K.2
Oberneder, R.3
Stahler, M.4
Haseke, N.5
Beck, J.6
Hofmann, R.7
Kindler, M.8
Kloepfer, P.9
Stief, C.10
-
99
-
-
0033119192
-
Intratumoral distribution of two consecutive injections of chimeric antibody G250 in primary renal cell carcinoma: Implications for fractionated dose radioimmunotherapy
-
Steffens MG, Boerman OC, Oyen WJ, Kniest PH, Witjes JA, Oosterhof GO, van Leenders GJ, Debruyne FM, Corstens FH, Oosterwijk E (1999) Intratumoral distribution of two consecutive injections of chimeric antibody G250 in primary renal cell carcinoma: implications for fractionated dose radioimmunotherapy. Cancer Res 59:1615-1619
-
(1999)
Cancer Res
, vol.59
, pp. 1615-1619
-
-
Steffens, M.G.1
Boerman, O.C.2
Oyen, W.J.3
Kniest, P.H.4
Witjes, J.A.5
Oosterhof, G.O.6
Van Leenders, G.J.7
Debruyne, F.M.8
Corstens, F.H.9
Oosterwijk, E.10
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