The Warburg effect: Why and how do cancer cells activate glycolysis in the presence of oxygen?

Anti-Cancer Agents in Medicinal Chemistry

Volumn 8, Issue 3, 2008, Pages 305-312

  López Lázaro, Miguel ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

Aerobic glycolysis inhibitors; Dysoxic metabolism; Hydrogen peroxide; Hypoxia inducible factor 1; Metabolism; Reactive oxygen species; Superoxide anion

Indexed keywords

5 (N,N DIMETHYL)AMILORIDE; ALPHA CHLOROHYDRIN; AMILORIDE; ANTINEOPLASTIC AGENT; APIGENIN; BERBERINE; BISPHOSPHONIC ACID DERIVATIVE; BROMOPYRUVIC ACID; CELECOXIB; DEOXYGLUCOSE; DICHLOROACETIC ACID; DIHYDROXYNAPHTHOIC ACID DERIVATIVE; GENISTEIN; IBUPROFEN; IMATINIB; INSULIN; LONIDAMINE; MANNOHEPTULOSE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; ORNIDAZOLE; OXAMIC ACID; OXYGEN; OXYTHIAMINE; RESVERATROL; SB 204990; THIOGLUCOSE; TOPOTECAN; TRASTUZUMAB; TUBERCIDIN; UNINDEXED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INVASION; CARCINOGENESIS; CELL HYPOXIA; CELL METABOLISM; CELL PH; CELL PROLIFERATION; CLEAR CELL CARCINOMA; CLINICAL TRIAL; DRUG EFFICACY; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE INACTIVATION; GENE MUTATION; GENETIC TRANSCRIPTION; GLYCOLYSIS; HUMAN; KIDNEY CARCINOMA; METASTASIS POTENTIAL; NEOPLASM; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PROSTATE HYPERTROPHY; PROTEIN EXPRESSION; ANIMAL; DRUG EFFECT; METABOLISM; PHYSIOLOGY; REVIEW;

ANIMALS; ANTINEOPLASTIC AGENTS; GLYCOLYSIS; HUMANS; NEOPLASMS; OXYGEN;

EID: 43549121719     PISSN: 18715206     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152008783961932     Document Type: Article

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