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Volumn 71, Issue 24, 2011, Pages 7558-7567

Phosphorylation of carbonic anhydrase IX controls its ability to mediate extracellular acidification in hypoxic tumors

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; BICARBONATE SODIUM COTRANSPORTER; CARBONATE DEHYDRATASE IX; CYCLIC AMP; PROTEIN TYROSINE KINASE A; SERINE; THREONINE;

EID: 84255199558     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-2520     Document Type: Article
Times cited : (116)

References (31)
  • 1
    • 44449091556 scopus 로고    scopus 로고
    • Molecular mechanisms of carbonic anhydrase IX-mediated pH regulation under hypoxia
    • Pastorekova S, Ratcliffe PJ, Pastorek J. Molecular mechanisms of carbonic anhydrase IX-mediated pH regulation under hypoxia. BJU Int 2008;101 (Suppl 4):8-15.
    • (2008) BJU Int , vol.101 , Issue.SUPPL. 4 , pp. 8-15
    • Pastorekova, S.1    Ratcliffe, P.J.2    Pastorek, J.3
  • 2
    • 58249094845 scopus 로고    scopus 로고
    • Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH
    • Chiche J, Ilc K, Laferriere J, Trottier E, Dayan F, Mazure NM, et al. Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH. Cancer Res 2009;69:358-68.
    • (2009) Cancer Res , vol.69 , pp. 358-368
    • Chiche, J.1    Ilc, K.2    Laferriere, J.3    Trottier, E.4    Dayan, F.5    Mazure, N.M.6
  • 3
    • 33745303045 scopus 로고    scopus 로고
    • Hypoxia signalling in cancer and approaches to enforce tumour regression
    • DOI 10.1038/nature04871, PII NATURE04871
    • Pouyssegur J, Dayan F, Mazure NM. Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 2006;441:437-43. (Pubitemid 44050138)
    • (2006) Nature , vol.441 , Issue.7092 , pp. 437-443
    • Pouyssegur, J.1    Dayan, F.2    Mazure, N.M.3
  • 5
    • 50649105780 scopus 로고    scopus 로고
    • Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths
    • Swietach P, Wigfield S, Cobden P, Supuran CT, Harris AL, Vaughan-Jones RD. Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths. J Biol Chem 2008;283:20473-83.
    • (2008) J Biol Chem , vol.283 , pp. 20473-20483
    • Swietach, P.1    Wigfield, S.2    Cobden, P.3    Supuran, C.T.4    Harris, A.L.5    Vaughan-Jones, R.D.6
  • 8
    • 67749145635 scopus 로고    scopus 로고
    • The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths
    • Swietach P, Patiar S, Supuran CT, Harris AL, Vaughan-Jones RD. The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths. J Biol Chem 2009;284:20299-310.
    • (2009) J Biol Chem , vol.284 , pp. 20299-20310
    • Swietach, P.1    Patiar, S.2    Supuran, C.T.3    Harris, A.L.4    Vaughan-Jones, R.D.5
  • 9
    • 79955538507 scopus 로고    scopus 로고
    • Catalysis and pH control by membrane-associated carbonic anhydrase IX in MDA-MB-231 breast cancer cells
    • Li Y, Tu C, Wang H, Silverman DN, Frost SC. Catalysis and pH control by membrane-associated carbonic anhydrase IX in MDA-MB-231 breast cancer cells. J Biol Chem 2011;286:15789-96.
    • (2011) J Biol Chem , vol.286 , pp. 15789-15796
    • Li, Y.1    Tu, C.2    Wang, H.3    Silverman, D.N.4    Frost, S.C.5
  • 10
    • 79953138420 scopus 로고    scopus 로고
    • Carbonic anhydrase IX (CA9) modulates tumor-associated cell migration and invasion
    • Shin HJ, Rho SB, Jung DC, Han IO, Oh ES, Kim JY. Carbonic anhydrase IX (CA9) modulates tumor-associated cell migration and invasion. J Cell Sci 2011;124:1077-87.
    • (2011) J Cell Sci , vol.124 , pp. 1077-1087
    • Shin, H.J.1    Rho, S.B.2    Jung, D.C.3    Han, I.O.4    Oh, E.S.5    Kim, J.Y.6
  • 11
    • 2542601328 scopus 로고    scopus 로고
    • Hypoxia inducible carbonic anhydrase IX, marker of tumor hypoxia, survival pathway and therapy target
    • Potter C, Harris AL. Hypoxia inducible carbonic anhydrase IX, marker of tumour hypoxia, survival pathway and therapy target. Cell Cycle 2004;3:164-7. (Pubitemid 40268690)
    • (2004) Cell Cycle , vol.3 , Issue.2 , pp. 164-167
    • Potter, C.1    Harris, A.L.2
  • 12
    • 42149164854 scopus 로고    scopus 로고
    • Cancer-associated carbonic anhydrases and their inhibition
    • DOI 10.2174/138161208783877893
    • Pastorekova S, Zatovicova M, Pastorek J. Cancer-associated carbonic anhydrases and their inhibition. Curr Pharm Des 2008;14:685-98. (Pubitemid 351736449)
    • (2008) Current Pharmaceutical Design , vol.14 , Issue.7 , pp. 685-698
    • Pastorekova, S.1    Zatovicova, M.2    Pastorek, J.3
  • 13
    • 38849143765 scopus 로고    scopus 로고
    • Carbonic anhydrases: Novel therapeutic applications for inhibitors and activators
    • DOI 10.1038/nrd2467, PII NRD2467
    • Supuran CT. Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. Nat Rev Drug Discov 2008;7:168-81. (Pubitemid 351194064)
    • (2008) Nature Reviews Drug Discovery , vol.7 , Issue.2 , pp. 168-181
    • Supuran, C.T.1
  • 14
    • 71749105278 scopus 로고    scopus 로고
    • Intact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX
    • Hulikova A, Zatovicova M, Svastova E, Ditte P, Brasseur R, Kettmann R, et al. Intact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX. FEBS Lett 2009;583:3563-8.
    • (2009) FEBS Lett , vol.583 , pp. 3563-3568
    • Hulikova, A.1    Zatovicova, M.2    Svastova, E.3    Ditte, P.4    Brasseur, R.5    Kettmann, R.6
  • 15
    • 0028111173 scopus 로고
    • Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment
    • Pastorek J, Pastorekova S, Callebaut I, Mornon JP, Zelnik V, Opavsky R, et al. Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment. Oncogene 1994;9:2877-88.
    • (1994) Oncogene , vol.9 , pp. 2877-2888
    • Pastorek, J.1    Pastorekova, S.2    Callebaut, I.3    Mornon, J.P.4    Zelnik, V.5    Opavsky, R.6
  • 16
    • 0030601349 scopus 로고    scopus 로고
    • Inhibition of protein kinase A phenocopies ectopic expression of hedgehog in the CNS of wild-type and cyclops mutant embryos
    • DOI 10.1006/dbio.1996.0209
    • Ungar AR, Moon RT. Inhibition of protein kinase A phenocopies ectopic expression of hedgehog in the CNS of wild-type and cyclops mutant embryos. Dev Biol 1996;178:186-91. (Pubitemid 26297251)
    • (1996) Developmental Biology , vol.178 , Issue.1 , pp. 186-191
    • Ungar, A.R.1    Moon, R.T.2
  • 17
    • 0023645848 scopus 로고
    • Expression of Cdnas for 2 isoforms of the catalytic subunit of camp-dependent protein-kinase
    • Uhler MD, Mcknight GS. Expression of Cdnas for 2 isoforms of the catalytic subunit of camp-dependent protein-kinase. J Biol Chem 1987;262:15202-7.
    • (1987) J Biol Chem , vol.262 , pp. 15202-15207
    • Uhler, M.D.1    Mcknight, G.S.2
  • 18
    • 28244451574 scopus 로고    scopus 로고
    • The role of carbonic anhydrase IX overexpression in kidney cancer
    • DOI 10.1016/j.ejca.2005.09.011, PII S0959804905008415
    • Dorai T, Sawczuk IS, Pastorek J, Wiernik PH, Dutcher JP. The role of carbonic anhydrase IX overexpression in kidney cancer. Eur J Cancer 2005;41:2935-47. (Pubitemid 41713134)
    • (2005) European Journal of Cancer , vol.41 , Issue.18 , pp. 2935-2947
    • Dorai, T.1    Sawczuk, I.S.2    Pastorek, J.3    Wiernik, P.H.4    Dutcher, J.P.5
  • 19
    • 0035413602 scopus 로고    scopus 로고
    • Physiological substrates of cAMP-dependent protein kinase
    • DOI 10.1021/cr000236l
    • Shabb JB. Physiological substrates of cAMP-dependent protein kinase. Chem Rev 2001;101:2381-411. (Pubitemid 35373025)
    • (2001) Chemical Reviews , vol.101 , Issue.8 , pp. 2381-2411
    • Shabb, J.B.1
  • 20
    • 43049121301 scopus 로고    scopus 로고
    • A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins
    • Arnold HK, Sears RC. A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins. Cancer Metastasis Rev 2008;27:147-58.
    • (2008) Cancer Metastasis Rev , vol.27 , pp. 147-158
    • Arnold, H.K.1    Sears, R.C.2
  • 23
    • 68149105927 scopus 로고    scopus 로고
    • Protons make tumor cells move like clockwork
    • Stock C, Schwab A. Protons make tumor cells move like clockwork. Pflugers Arch-Eur J Physiol 2009;458:981-92.
    • (2009) Pflugers Arch-Eur J Physiol , vol.458 , pp. 981-992
    • Stock, C.1    Schwab, A.2
  • 26
    • 34848884803 scopus 로고    scopus 로고
    • Intermittent hypoxia changes HIF-1alpha phosphorylation pattern in endothelial cells: Unravelling of a new PKA-dependent regulation of HIF-1alpha
    • Toffoli S, Feron O, Raes M, Michiels C. Intermittent hypoxia changes HIF-1alpha phosphorylation pattern in endothelial cells: unravelling of a new PKA-dependent regulation of HIF-1alpha. Biochim Biophys Acta 2007;1773:1558-71.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 1558-1571
    • Toffoli, S.1    Feron, O.2    Raes, M.3    Michiels, C.4
  • 28
  • 29
    • 67649391241 scopus 로고    scopus 로고
    • The intracellular juxtamembrane domain of the epidermal growth factor (EGF) receptor is responsible for the allosteric regulation of EGF binding
    • 2009
    • Macdonald-Obermann JL, Pike LJ. (2009) The intracellular juxtamembrane domain of the epidermal growth factor (EGF) receptor is responsible for the allosteric regulation of EGF binding. J Biol Chem 2009;284:13570-6.
    • (2009) J Biol Chem , vol.284 , pp. 13570-13576
    • Macdonald-Obermann, J.L.1    Pike, L.J.2
  • 30
    • 0040777075 scopus 로고    scopus 로고
    • Model of a quinary structure between krebs TCA cycle enzymes: A model for the metabolon
    • DOI 10.1021/bi972011j
    • Velot C, Moxin MB, Teige M, Srere P. Model of a quinary structure between Krebs TCA cycle enzymes: A model for the metabolon. Biochemistry 1997;36:14271-6. (Pubitemid 27509918)
    • (1997) Biochemistry , vol.36 , Issue.47 , pp. 14271-14276
    • Velot, C.1    Mixon, M.B.2    Teige, M.3    Srere, P.A.4
  • 31
    • 1842852597 scopus 로고    scopus 로고
    • Induction by hypoxia combined with low glucose or low bicarbonate and high posttranslational stability upon reoxygenation contribute to carbonic anhydrase IX expression in cancer cells
    • Rafajova M, Zatovicova M, Kettmann R, Pastorek J, Pastorekova S. Induction by hypoxia combined with low glucose or low bicarbonate and high posttranslational stability upon reoxygenation contribute to carbonic anhydrase IX expression in cancer cells. Int J Oncol 2004;24:995-1004.
    • (2004) Int J Oncol , vol.24 , pp. 995-1004
    • Rafajova, M.1    Zatovicova, M.2    Kettmann, R.3    Pastorek, J.4    Pastorekova, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.