Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer

American Journal of Pathology

Volumn 158, Issue 3, 2001, Pages 905-919

  Ivanov, Sergey ^a   Liao, Shu Yuan ^d   Ivanova, Alla ^a   Danilkovitch Miagkova, Alla ^a   Tarasova, Nadezhda ^b   Weirich, Gregor ^a   Merrill, Marsha J ^c   Proescholdt, Martin A ^c   Oldfield, Edward H ^c   Lee, Joshua ^a   Zavada, Jan ^f   Waheed, Abdul ^e   Sly, William ^e   Lerman, Michael I ^a   Stanbridge, Eric J ^d  

^a SAIC FREDERICK INC   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f INSTITUTE OF MATHEMATICS   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONATE DEHYDRATASE; GENE PRODUCT; PROTEIN CA12; PROTEIN CA9; RNA; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; CANCER; CELL CULTURE; CELL LINE; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; IMMUNOHISTOCHEMISTRY; METASTASIS; PH; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TUMOR GROWTH; VON HIPPEL LINDAU DISEASE;

EID: 0035107383     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64038-2     Document Type: Article

References (52)

1. Hypoxia, clonal selection, and the role of HIF-1 in tumor progression
2. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
3. Oncogenic alterations of metabolism
4. Causes and consequences of tumour acidity and implications for treatment
5. 2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation
6. Transport of molecules, particles, and cells in solid tumors
7. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
8. Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene
9. Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes
10. The von Hippel-Lindau tumour suppressor protein: New perspectives
11. 2 homeostasis by hypoxia-inducible factor 1
12. Oxygen sensing and molecular adaptation to hypoxia
13. Hypoxia and the regulation of gene expression
14. The VHL tumour-suppressor gene paradigm
15. One ring to rule a superfamily of E3 ubiquitin ligases
16. VHL: A very hip ligase
17. Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex
18. Mechanism of dexamethasone suppression of brain tumor-associated vascular permeability in rats. Involvement of the glucocorticoid receptor and vascular permeability factor
19. Expression of MaTu-MN protein in human tumor cultures and in clinical specimens
20. Identification of carbonic anhydrase XII as the membrane isozyme expressed in the normal human endometrial epithelium
21. Identification of the MN antigen as a diagnostic biomarker of cervical intraepithelial neoplasia and cervical carcinoma
22. Identification of the MN/CA9 protein as a reliable diagnostic biomarker of clear cell carcinoma of the kidney
23. Expression of the tumor-associated gene MN: A potential biomarker for human renal cell carcinoma
24. Immunohistochemical study of colorectar tumors for expression of a novel transmembrane carbonic anhydrase, MN/CA IX, with potential value as a marker of cell proliferation
25. Immunohistochemistry of carbonic anhydrase isozyme IX (MN/CA IX) in human gut reveals polarized expression in the epithelial cells with the highest proliferative capacity
26. Expression of a novel transmembrane carbonic anhydrase isozyme XII in normal human gut and colorectal tumors
27. Human carbonic anhydrase XII: cDNA cloning, expression, and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cell cancers
28. Structure of the vacuolar ATPase by electron microscopy
29. +-ATPase
30. An electrophysiological comparison of voltage-gated proton channels, other ion channels, and other proton channels
31. +-exchangers
32. The proton-linked monocarboxylate transporter (MCT) family: Structure, function and regulation
33. Human carbonic anhydrases and carbonic anhydrase deficiencies
34. Catalysis and inhibition of human carbonic anhydrase IV
35. Inherited carcinomas of the kidney
36. Matrix metalloproteinases: Multifunctional contributors to tumor progression
37. Openings between defective endothelial cells explain tumor vessel leakiness
38. The importance of aquaporin water channel protein structures
39. Aquaporin water channels and lung physiology
40. Expression of the MN antigen in cervical Papanicolaou smears is an early diagnostic biomarker of cervical dysplasia
41. Expression of MN/CA9 protein in Papanicolaou smears containing atypical glandular cells of undetermined significance is a diagnostic biomarker of cervical dysplasia and neoplasia
42. Monoclonal antibody G 250 recognizes a determinant present in renal cell carcinoma and absent from normal kidney
43. MN/CA IX/G250 as a potential target for immunotherapy of renal cell carcinomas
44. Phase I/II radioimmunotherapy trial with iodine-131-labeled monoclonal antibody G250 in metastatic renal cell carcinoma
45. Targeted toxins
46. Phase I radioimmunotherapy of metastatic renal cell carcinoma with 1311-labeled chimeric monoclonal antibody G250
47. MN antigen expression in normal, preneoplastic, and neoplastic esophagus: A clinicopathological study of a new cancer-associated biomarker
48. Carbonic anhydrase IX antigen differentiates between preneoplastic and malignant lesions in nonsmall cell lung carcinomas
49. Carbonic anhydrase inhibitor suppresses invasion of renal cancer cells in vitro
50. The development of topical carbonic anhydrase inhibitors
51. Sulfonamides and secretion of aqueous humor