Unifying Family A GPCR Theories of Activation

Pharmacology and Therapeutics

Volumn 143, Issue 1, 2014, Pages 51-60

  Tehan, Benjamin G ^a   Bortolato, Andrea ^a   Blaney, Frank E ^a   Weir, Malcolm P ^a   Mason, Jonathan S ^a  

^a Heptares Therapeutics Ltd   (United Kingdom)

Author keywords

Activation; Conservational analysis; Constitutive activity; GPCR

Indexed keywords

ADENOSINE A2 RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; G PROTEIN COUPLED RECEPTOR; GLYCOPROTEIN; MUSCARINIC M2 RECEPTOR; RHODOPSIN;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; ANIMAL; CHEMICAL PHENOMENA; CHEMISTRY; PHYSIOLOGY; STRUCTURE ACTIVITY RELATION;

ANIMALS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; RECEPTORS, G-PROTEIN-COUPLED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84898901491     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2014.02.004     Document Type: Review

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