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Volumn 83, Issue 2, 1998, Pages 492-498

Hyperfunctioning thyroid nodules in toxic multinodular goiter share activating thyrotropin receptor mutations with solitary toxic adenoma

Author keywords

[No Author keywords available]

Indexed keywords

THYROTROPIN; THYROTROPIN RECEPTOR;

EID: 15144351998     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.83.2.492     Document Type: Article
Times cited : (118)

References (35)
  • 1
    • 0002214655 scopus 로고    scopus 로고
    • Toxic adenoma and toxic multinodular goiter
    • Braverman LE, Utiger RD, eds. Philadelphia: Lippincott-Raven
    • Hay ID, Morris JC. 1996 Toxic adenoma and toxic multinodular goiter. In: Braverman LE, Utiger RD, eds. Werner and Ingbar's the thyroid. Philadelphia: Lippincott-Raven; 566-572.
    • (1996) Werner and Ingbar's the Thyroid , pp. 566-572
    • Hay, I.D.1    Morris, J.C.2
  • 2
    • 0023444080 scopus 로고
    • The autonomously functioning thyroid nodule: Goetsch's disease
    • Hamburger JI. 1987 The autonomously functioning thyroid nodule: Goetsch's disease. Endocr Rev. 8:439-450.
    • (1987) Endocr Rev , vol.8 , pp. 439-450
    • Hamburger, J.I.1
  • 3
    • 0023220109 scopus 로고
    • Plummer's disease: Localized thyroid autonomy
    • Wiener JD. 1987 Plummer's disease: localized thyroid autonomy. J Endocrinol Invest. 10:207-224.
    • (1987) J Endocrinol Invest , vol.10 , pp. 207-224
    • Wiener, J.D.1
  • 4
    • 0027369421 scopus 로고
    • Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas
    • Parma J, Duprez L, Van Sande J, et al. 1993 Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas. Nature. 365:649-651.
    • (1993) Nature , vol.365 , pp. 649-651
    • Parma, J.1    Duprez, L.2    Van Sande, J.3
  • 5
    • 0028588698 scopus 로고
    • Identification and functional characterization of two new somatic mutations causing constitutive activation of the TSH receptor in hyperfunctioning autonomous adenomas of the thyroid
    • Paschke R, Tonacchera M, Van Sande J, Parma J, Vassart G. 1994 Identification and functional characterization of two new somatic mutations causing constitutive activation of the TSH receptor in hyperfunctioning autonomous adenomas of the thyroid. J Clin Endocrinol Metab. 79:1785-1789.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 1785-1789
    • Paschke, R.1    Tonacchera, M.2    Van Sande, J.3    Parma, J.4    Vassart, G.5
  • 8
    • 0029093051 scopus 로고
    • Rarity of oncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in Japan
    • 1195
    • Takeshita A, Nagayama Y, Yokoyama N, et al. 1995 Rarity of oncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in Japan. J Clin Endocrinol Metab. 1195:80:2607-2610.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 2607-2610
    • Takeshita, A.1    Nagayama, Y.2    Yokoyama, N.3
  • 9
    • 1542501222 scopus 로고
    • Studies on the prevalence of TSH receptor mutations in a large series of consecutive hyperfunctioning adenomas
    • Abstract
    • Porcellini A, Tassi V, Ciullo I, et al. 1995 Studies on the prevalence of TSH receptor mutations in a large series of consecutive hyperfunctioning adenomas. Thyroid. 5[Suppl 1]:S-8. (Abstract).
    • (1995) Thyroid , vol.5 , Issue.1 SUPPL.
    • Porcellini, A.1    Tassi, V.2    Ciullo, I.3
  • 10
    • 0029964174 scopus 로고    scopus 로고
    • Thyrotropin receptor gene alterations in thyroid hyperfunctioning adenomas
    • Russo D, Arturi F, Suarez HG, et al. 1996 Thyrotropin receptor gene alterations in thyroid hyperfunctioning adenomas. J Clin Endocrinol Metab. 81:1548-1551.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 1548-1551
    • Russo, D.1    Arturi, F.2    Suarez, H.G.3
  • 11
    • 0003853631 scopus 로고    scopus 로고
    • Absence of mutations in the TSH receptor and the Gsα subunit in nodules and adenomas of multinodular goiters and identification of a new activating mutation (Tyr 601 Asp) in a solitary toxic adenoma
    • Abstract
    • Kopp P, Wilkes B, Gu WX, Jameson JL. 1997 Absence of mutations in the TSH receptor and the Gsα subunit in nodules and adenomas of multinodular goiters and identification of a new activating mutation (Tyr 601 Asp) in a solitary toxic adenoma. Thyroid 6[Suppl 1]:S-9. (Abstract).
    • (1997) Thyroid , vol.6 , Issue.1 SUPPL.
    • Kopp, P.1    Wilkes, B.2    Gu, W.X.3    Jameson, J.L.4
  • 13
    • 9044240477 scopus 로고    scopus 로고
    • Functional characteristics of three new germline mutations of the TSH receptor gene causing autosomal dominant toxic hyperplasia
    • Tonacchera M, Van Sande J, Cetani F, et al. 1996 Functional characteristics of three new germline mutations of the TSH receptor gene causing autosomal dominant toxic hyperplasia. J Clin Endocrinol Metab. 81:547-554.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 547-554
    • Tonacchera, M.1    Van Sande, J.2    Cetani, F.3
  • 14
    • 0024596736 scopus 로고
    • Selective inactivation of the exonuclease activity of bacteriophage T7 DNA polymerase by in vitro mutagenesis
    • Tabor S, Richardson CC. 1989 Selective inactivation of the exonuclease activity of bacteriophage T7 DNA polymerase by in vitro mutagenesis. J Biol Chem. 264:6447-6458.
    • (1989) J Biol Chem , vol.264 , pp. 6447-6458
    • Tabor, S.1    Richardson, C.C.2
  • 15
    • 0022506056 scopus 로고
    • Thyroid stimulating antibody mimics thyrotropin in its ability to desensitize 3′-5′-monophosphate response to acute stimulation in continuously cultured thyroid cells (FRT-L5)
    • Vitti P, Chiovato L, Ceccarelli P, et al. 1986 Thyroid stimulating antibody mimics thyrotropin in its ability to desensitize 3′-5′-monophosphate response to acute stimulation in continuously cultured thyroid cells (FRT-L5). J Clin Endocrinol Metab. 454-458.
    • (1986) J Clin Endocrinol Metab , pp. 454-458
    • Vitti, P.1    Chiovato, L.2    Ceccarelli, P.3
  • 16
    • 0021821094 scopus 로고
    • Bovine thyrotropin has a specific bioactivity 5- to 10-fold that of previous estimates for highly purified hormone
    • Rapoport B, Seto P. 1985 Bovine thyrotropin has a specific bioactivity 5- to 10-fold that of previous estimates for highly purified hormone. Endocrinology 116:1379-1382.
    • (1985) Endocrinology , vol.116 , pp. 1379-1382
    • Rapoport, B.1    Seto, P.2
  • 17
    • 0029012098 scopus 로고
    • Interpretation of binding curves obtained with high receptor concentrations: Practical aid for computer analysis
    • Swillens S. 1995 Interpretation of binding curves obtained with high receptor concentrations: practical aid for computer analysis. Mol Pharmacol 47:1197-1203.
    • (1995) Mol Pharmacol , vol.47 , pp. 1197-1203
    • Swillens, S.1
  • 18
    • 0343553834 scopus 로고    scopus 로고
    • Diversity and prevalence of somatic mutations in the TSH receptor gene as a cause of toxic adenoma
    • Abstract
    • Duprez L, Parma J, Dumont JE, Hermans J, Vassart G. 1996 Diversity and prevalence of somatic mutations in the TSH receptor gene as a cause of toxic adenoma. J Endocrinol Invest. 19[Suppl 6]:69. (Abstract).
    • (1996) J Endocrinol Invest , vol.19 , Issue.6 SUPPL. , pp. 69
    • Duprez, L.1    Parma, J.2    Dumont, J.E.3    Hermans, J.4    Vassart, G.5
  • 19
    • 0008786451 scopus 로고    scopus 로고
    • Identification of different thyrotropin receptor mutations in toxic multinodular goiter
    • Abstract
    • Paschke R, Fuehrer D, Holzapfel HP. 1996 Identification of different thyrotropin receptor mutations in toxic multinodular goiter. J Endocrinol Invest. 19[Suppl 6]:28. (Abstract).
    • (1996) J Endocrinol Invest , vol.19 , Issue.6 SUPPL. , pp. 28
    • Paschke, R.1    Fuehrer, D.2    Holzapfel, H.P.3
  • 21
    • 0028113398 scopus 로고
    • Constitutive activation of cyclic AMP but not phosphatidylinositol signaling caused by four mutations in the 6th transmembrane helix of the human TSH receptor
    • Kosugi S, Shenker A, Mori T. 1994 Constitutive activation of cyclic AMP but not phosphatidylinositol signaling caused by four mutations in the 6th transmembrane helix of the human TSH receptor. FEBS Lett. 356:291-294.
    • (1994) FEBS Lett , vol.356 , pp. 291-294
    • Kosugi, S.1    Shenker, A.2    Mori, T.3
  • 22
    • 0028880502 scopus 로고
    • Somatic mutations in the VI transmembrane segment of the thyrotropin receptor constitutively activate cAMP signalling in thyroid hyperfunctioning adenomas
    • Porcellini A, Ciullo I, Pannain S, Fenzi GF, Awedimento E 1995 Somatic mutations in the VI transmembrane segment of the thyrotropin receptor constitutively activate cAMP signalling in thyroid hyperfunctioning adenomas Oncogene. 11:1089-1093.
    • (1995) Oncogene , vol.11 , pp. 1089-1093
    • Porcellini, A.1    Ciullo, I.2    Pannain, S.3    Fenzi, G.F.4    Awedimento, E.5
  • 23
  • 24
    • 0024403390 scopus 로고
    • Natural heterogeneity of thyroid cells: The basis for understanding thyroid function and nodular goiter growth
    • Studer H, Peter HJ, Gerber H. 1989 Natural heterogeneity of thyroid cells: the basis for understanding thyroid function and nodular goiter growth Endocr Rev. 10:125-135.
    • (1989) Endocr Rev , vol.10 , pp. 125-135
    • Studer, H.1    Peter, H.J.2    Gerber, H.3
  • 25
    • 0026781160 scopus 로고
    • Histomorphological and immunohistochemical evidence that human nodular goiters grow by episodic replication of multiple clusters of thyroid follicular cells
    • Studer H, Gerber H, Zbaeren J, Peter HJ. 1992 Histomorphological and immunohistochemical evidence that human nodular goiters grow by episodic replication of multiple clusters of thyroid follicular cells. J Clin Endocrinol Metab. 875:1151-1158.
    • (1992) J Clin Endocrinol Metab , vol.875 , pp. 1151-1158
    • Studer, H.1    Gerber, H.2    Zbaeren, J.3    Peter, H.J.4
  • 26
    • 0029081447 scopus 로고
    • Mechanisms of nonneoplastic endocrine hyperplasia: A changing concept: A review focused on the thyroid gland
    • Studer H, Derwahl M. 1995 Mechanisms of nonneoplastic endocrine hyperplasia: a changing concept: a review focused on the thyroid gland. Endocr Rev. 16:411-426.
    • (1995) Endocr Rev , vol.16 , pp. 411-426
    • Studer, H.1    Derwahl, M.2
  • 29
  • 30
    • 0029032529 scopus 로고
    • Decrease of incidence of toxic nodular goiter in a region of Switzerland after full correction of mild iodine deficiency
    • Baltisberger BL, Minder CE, Burgi H. 1995 Decrease of incidence of toxic nodular goiter in a region of Switzerland after full correction of mild iodine deficiency. Eur J Endocrinol. 132:546-549.
    • (1995) Eur J Endocrinol , vol.132 , pp. 546-549
    • Baltisberger, B.L.1    Minder, C.E.2    Burgi, H.3
  • 34
    • 0026661582 scopus 로고
    • Physiological and pathological regulation of thyroid cell proliferation and differentiation by thyrotropin and other factors
    • Dumont JE, Lamy F, Roger P, Maenhaut C. 1992 Physiological and pathological regulation of thyroid cell proliferation and differentiation by thyrotropin and other factors. Physiol Rev. 72:667-697.
    • (1992) Physiol Rev , vol.72 , pp. 667-697
    • Dumont, J.E.1    Lamy, F.2    Roger, P.3    Maenhaut, C.4
  • 35
    • 8544221172 scopus 로고    scopus 로고
    • Diversity and prevalence of somatic mutations in the thyrotropin receptor and Gsα genes as a cause of toxic thyroid adenomas
    • Parma J, Duprez L, Van Sande J, et al. 1997 Diversity and prevalence of somatic mutations in the thyrotropin receptor and Gsα genes as a cause of toxic thyroid adenomas. J Clin Endocrinol Metab. 82:2695-2701.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2695-2701
    • Parma, J.1    Duprez, L.2    Van Sande, J.3


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