Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

Nature

Volumn 482, Issue 7386, 2012, Pages 547-551

  Haga, Kazuko ^a   Kruse, Andrew C ^b   Asada, Hidetsugu ^c,d   Yurugi Kobayashi, Takami ^c,d   Shiroishi, Mitsunori ^d,e   Zhang, Cheng ^b   Weis, William I ^b   Okada, Tetsuji ^a   Kobilka, Brian K ^b   Haga, Tatsuya ^a   Kobayashi, Takuya ^c,d,f  

^a GAKUSHUIN UNIVERSITY   (Japan)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c KYOTO UNIVERSITY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e KYUSHU UNIVERSITY   (Japan)

^f KYOTO UNIVERSITY FACULTY OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BINDING PROTEIN; MUSCARINIC M2 RECEPTOR; QUINUCLIDINYL BENZILATE; TYROSINE;

AMINO ACID; CARDIOVASCULAR DISEASE; HOMOLOGY; LIGAND; MEMBRANE; NERVOUS SYSTEM; PHYSIOLOGICAL RESPONSE; PROTEIN;

ALLOSTERISM; ARTICLE; BINDING SITE; DRUG RECEPTOR BINDING; HUMAN; MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRUCTURE ANALYSIS;

ACETYLCHOLINE; ACETYLCHOLINESTERASE; ALLOSTERIC REGULATION; BINDING SITES; CARRIER PROTEINS; CHOLINERGIC ANTAGONISTS; CRYSTALLOGRAPHY, X-RAY; EVOLUTION, MOLECULAR; HUMANS; LIGANDS; MODELS, MOLECULAR; PROTEIN CONFORMATION; QUINUCLIDINYL BENZILATE; RECEPTOR, MUSCARINIC M2; TYROSINE;

EID: 84862777405     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10753     Document Type: Article

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