Constitutive activation of opsin by mutation of methionine 257 on transmembrane helix 6

Biochemistry

Volumn 37, Issue 22, 1998, Pages 8253-8261

  Han, May ^a,b   Smith, Steven O ^b   Sakmar, Thomas P ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; METHIONINE; OPSIN; RETINAL; RHODOPSIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL STRAIN COS1; NONHUMAN; PHOTOACTIVATION; PRIORITY JOURNAL; PROTEIN CONFORMATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CATTLE; COS CELLS; DRUG SYNERGISM; MEMBRANE PROTEINS; METHIONINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OPSIN; PROTEIN STRUCTURE, SECONDARY; RHODOPSIN; SPECTROPHOTOMETRY, ULTRAVIOLET; TRANSDUCIN;

EID: 0032474444     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980147r     Document Type: Article

References (68)

1. Cotecchia, S., Exum, S., Caron, M. G., and Lefkowitz, R. J. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 2896-2890.
2. Tiberi, M., and Caron, M. G. (1994) J. Biol. Chem. 269, 27925-27931.
3. Cohen, D. P., Thaw, C. N., Varma, A., Gershengorn, M. C., and Nussenzveig, D. R. (1997) Endocrinology 138, 1400-1405.
4. Bond, R. A., Leff, P., Johnson, T. D., Milano, C. A., Rockeman, H. A., McMinn, T. R., Apparsundaram, S., Hyek, M. F., Kenakin, T. P., Allen, L. F., and Lefkowitz, R. J. (1995) Nature 374, 272-276.
5. Burstein, E. S., Spalding, T. A., and Brann, M. R. (1997) Mol. Pharmacol. 51, 312-319.
6. Shenker, A., Laue, L., Kosugi, S., Merendino, J. J., Jr., Minegishi, T., and Cutler, G. B., Jr. (1993) Nature 365, 652-654.
7. Laue, L., Chan, W. Y., Hsueh, A. J. W., Kudo, M., Hsu, S. Y., Wu, S. M., Blomberg, L., and Cutler, G. B., Jr. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 1906-1910.
8. Kosugi, S., Mori, T., and Shenker, A. (1996) J. Biol. Chem. 271, 31813-31817.
9. Parma, J., Duprez, L., van Sande, J., Cochaux, P., Gervy, C., Mockel, J., Dumont, J., and Vassart, G. (1993) Nature 365, 649-651.
10. van Sande, J., Parma, J., Tonacchera, M., Swillens, S., Dumont, J., and Vassart, G. (1995) J. Clin. Endocrinol. Metab. 80, 2577-2585.
11. Parma, J., van Sande, J., Swillens, S., Tonacchera, M., Dumont, J., and Vassart, G. (1995) Mol. Endocrinol. 9, 725-733.
12. Pollak, M. R., Brown, E. M., Estep, H. L., McLaine, P. N., Kifor, O., Park, J., Hebert, S. C., Seidman, C. E., and Seidman, J. G. (1994) Nat. Genet. 8, 303-307.
13. Schipani, E., Kruse, K., and Jüppner, H. (1995) Science 268, 98-99.
14. Arvanitakis, L., Geras-Raaka, E., Varma, A., Gershengorn, M. C., and Cesarman, E. (1997) Nature 385, 347-350.
15. Rao, V. R., and Oprian, D. D. (1996) Annu. Rev. Biophys. Biomol. Struct. 25, 287-314.
16. Dryja, T. P., Berson, E. L., Rao, V. R., and Oprian, D. D. (1993) Nat. Genet. 4, 280-283.
17. Sieving, P. A., Richards, J. E., Naarendorp, F., Bingham, E. L., Scott, K., and Alpern, M. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 880-884.
18. Keen, T. J., Inglehearn, C. F., Lester, D. H., Bashir, R., Jay, M., Bird, A. C., and Jay, B. (1991) Genomics 11, 199-205.
19. Sullivan, J. M., Scott, K. M., Falls, H. F., Richards, J. E., and Sieving, P. A. (1993) Invest. Ophthalmol. Visual Sci. 34, 11494.
20. Rim, J., and Oprian, D. D. (1995) Biochemistry 34, 11938-11945.
21. Robinson, P. R., Cohen, G. B., Zhukovsky, E. A., and Oprian, D. D. (1992) Neuron 9, 719-725.
22. Rao, V. R., Cohen, G. B., and Oprian, D. D. (1994) Nature 367, 639-642.
23. Fahmy, K., Zvyaga, T. A., Sakmar, T. P., and Siebert, F. (1996) Biochemistry 35, 15065-15073.
24. Richard, E. A., and Lisman, J. E. (1992) Nature 356, 336-338.
25. Li, T., Franson, W. K., Gordon, J. W., Berson, E. L., and Dryja, T. P. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 3551-3555.
26. van Rhee, A. M., and Jacobson, K. A. (1996) Drug Dev. Res. 37, 1-38.
27. Porcellini, A., Ciullo, I., Laviola, L., Amabile, G., Fenzi, G., and Avvedimento, V. E. (1994) J. Clin. Endocrinol. Metab. 79, 657-661.
28. Kosugi, S., and Mori, T. (1996) Biochem. Biophys. Res. Commun. 222, 713-717.
29. Han, M., Lin, S. W., Minkova, M., Smith, S. O., and Sakmar, T. P. (1996) J. Biol. Chem. 271, 32337-32342.
30. Leff, P. (1995) Trends Pharmacol. Sci. 16, 89-97.
31. Lefkowitz, R. J., Cotecchia, S., Samama, P., and Costa, T. (1993) Trends Pharmacol. Sci. 14, 303-307.
32. Lo, K., Jones, S. S., Hackett, N. R., and Khorana, H. G. (1984) Proc. Natl. Acad. Sci. U.S.A. 81, 2285-2289.
33. Ferretti, L., Karnik, S. S., Khorana, H. G., Nassal, M., and Oprian, D. D. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 599-603.
34. Franke, R. R., Sakmar, T. P., Oprian, D. D., and Khorana, H. G. (1988) J. Biol. Chem. 263, 2119-2122.
35. Han, M., Lin, S. W., Smith, S. O., and Sakmar, T. P. (1996) J. Biol. Chem. 271, 32330-32336.
36. Kaushal, S., and Khorana, H. G. (1994) Biochemistry 33, 6121-6128.
37. Wimley, W. C., and White, S. H. (1996) Nat. Struct. Biol. 3, 842-848.
38. Chothia, C. (1975) Nature 254, 304-311.
39. Kjelsberg, M. A., Cotecchia, S., Ostrowski, J., Caron, M. G., and Lefkowitz, R. J. (1992) J. Biol. Chem. 267, 1430-1433.
40. Scheer, A., Fanelli, F., Costa, T., de Benedetti, P. G., and Cotecchia, S. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 808-813.
41. Cohen, G. B., Yang, T., Robinson, P. R., and Oprian, D. D. (1993) Biochemistry 32, 6222-6115.
42. Fahmy, K., and Sakmar, T. P. (1993) Biochemistry 32, 7229-7236.
43. Amis, S., Fahmy, K., Hofmann, K. P., and Sakmar, T. P. (1994) J. Biol. Chem. 269, 23879-23881.
44. Schertler, G. F. X., Villa, C., and Henderson, R. (1993) Nature 362, 770-772.
45. Baldwin, J. M. (1993) EMBO J. 12, 1693-1703.
46. Shieh, T., Han, M., Sakmar, T. P., and Smith, S. O. (1997) J. Mol. Biol. 269, 373-384.
47. Farrens, D. L., Altenbach, C., Yang, K., Hubbell, W. L., and Khorana, H. G. (1996) Science 274, 768-770.
48. Probst, W. C., Snyder, L. A., Schuster, D. I., Brosius, J., and Sealfon, S. C. (1992) DNA Cell Biol. 11, 1-20.
49. Unger, V. M., Hargrave, P. A., Baldwin, J. M., and Schertler, G. F. X. (1997) Nature 389, 203-206.
50. Farahbakhsh, Z. T., Ridge, K. D., Khorana, H. G., and Hubbell, W. L. (1995) Biochemistry 34, 8812-8819.
51. Altenbach, C., Yang, K., Farrens, D. L., Farahbakhsh, Z. T., Khorana, H. G., and Hubbell, W. L. (1996) Biochemistry 35, 12470-12478.
52. Sheikh, S., Zvyaga, T. A., Lichtarge, O., Sakmar, T. P., and Bourne, H. R. (1996) Nature 383, 347-350.
53. Cohen, G. B., Oprian, D. D., Yang, T., and Robinson, P. R. (1992) Biochemistry 31, 12592-12601.
54. König B., Arendt, A., McDowell, J. H., Kahlert, M., Hargrave, P. A., and Hofmann, K. P. (1989) Proc. Natl. Acad. Sci. U.S.A. 86, 6878-6882.
55. Franke, R. R., Sakmar, T. P., Graham, R. M., and Khorana, H. G. (1992) J. Biol. Chem. 267, 14767-14774.
56. Strader, C. D., Fong, T. M., Tota, M. R., and Underwood, D. (1994) Annu. Rev. Biochem. 63, 101-132.
57. Franke, R. R., König, B., Sakmar, T. P., Khorana, H. G., and Hofmann, K. P. (1990) Science 250, 122-125.
58. Fahmy, K., Siebert, F., and Sakmar, T. P. (1995) Biophys. Chem. 56, 171-181.
59. Hwa, J., Gaivin, R., Porter, J. E., and Perez, D. M. (1997) Biochemistry 36, 633-639.
60. Bhogal, N., Donnelly, D., and Findlay, J. B. (1994) J. Biol. Chem. 269, 27269-27274.
61. Kremer, H., Kraaij, R., Toledo, S. P. A., Post, M., Friedman, J. B., Hayashida, C. Y., van Reen, M., Milgrom, E., Ropers, H., Mariman, E., Themmen, A. P. N., and Brunner, H. G. (1995) Nat. Genet. 9, 160-164.
62. Jäger, S., Palczewski, K., and Hofmann, K. P. (1996) Biochemistry 35, 2901-2908.
63. Han, M., Lou, J., Nakanishi, K., Sakmar, T. P., and Smith, S. O. (1997) J. Biol. Chem. 272, 23081-23085.
64. Ren, Q., Kurose, H., Lefkowitz, R. J., and Cotecchia, S. (1993) J. Biol. Chem. 268, 16483-16487.
65. Kremer, H., Mariman, E., Otten, B. J., Mol, G. W., Jr., Stoelinga, G. B. A., Wit, J. M., Jansen, M., Drop, S. L., Faas, B., Ropers, H.-H., and Brunner, H. G. (1993) Hum. Mol. Genet. 2, 1779-1783.
66. Yano, K., Saji, M., Hidaka, A., Moriya, N., Okuno, A., Kohn, L. D., and Cutler, G. B., Jr. (1995) J. Clin. Endocrinol. Metab. 80, 1162-1168.
67. Konopka, J. B., Margarit, S. M., and Dube, P. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 6764-6769.
68. Sung, C.-H., Davenport, C. M., and Nathans, J. (1993) J. Biol. Chem. 268, 26645-26649.