-
1
-
-
33751547539
-
How many drug targets are there?
-
Overington, J.P., Al-Lazikani, B. and Hopkins, A.L. (2006) How many drug targets are there? Nat. Rev. Drug Discov., 5, 993-996.
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 993-996
-
-
Overington, J.P.1
Al-Lazikani, B.2
Hopkins, A.L.3
-
2
-
-
84878371294
-
International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: Recommendations for new pairings with cognate ligands
-
Davenport, A.P., Alexander, S.P., Sharman, J.L., Pawson, A.J., Benson, H.E., Monaghan, A.E., Liew, W.C., Mpamhanga, C.P., Bonner, T.I., Neubig, R.R. et al. (2013) International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands. Pharmacol. Rev., 65, 967-986.
-
(2013)
Pharmacol. Rev.
, vol.65
, pp. 967-986
-
-
Davenport, A.P.1
Alexander, S.P.2
Sharman, J.L.3
Pawson, A.J.4
Benson, H.E.5
Monaghan, A.E.6
Liew, W.C.7
Mpamhanga, C.P.8
Bonner, T.I.9
Neubig, R.R.10
-
3
-
-
0037020329
-
Drug design strategies for targeting G-protein-coupled receptors
-
Klabunde, T. and Hessler, G. (2002) Drug design strategies for targeting G-protein-coupled receptors. Chembiochem, 3, 928-944.
-
(2002)
Chembiochem
, vol.3
, pp. 928-944
-
-
Klabunde, T.1
Hessler, G.2
-
4
-
-
84871967576
-
Polypharmacology: Drug discovery for the future
-
Reddy, A.S. and Zhang, S. (2013) Polypharmacology: drug discovery for the future. Exp. Rev. Clin. Pharmacol., 6, 41-47.
-
(2013)
Exp. Rev. Clin. Pharmacol.
, vol.6
, pp. 41-47
-
-
Reddy, A.S.1
Zhang, S.2
-
5
-
-
78651297517
-
GPCRDB: Information system for G protein-coupled receptors
-
Vroling, B., Sanders, M., Baakman, C., Borrmann, A., Verhoeven, S., Klomp, J., Oliveira, L., de Vlieg, J. and Vriend, G. (2011) GPCRDB: information system for G protein-coupled receptors. Nucleic Acids Res., 39, 309-319.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 309-319
-
-
Vroling, B.1
Sanders, M.2
Baakman, C.3
Borrmann, A.4
Verhoeven, S.5
Klomp, J.6
Oliveira, L.7
De Vlieg, J.8
Vriend, G.9
-
6
-
-
0037252680
-
GPCRDB information system for G proteincoupled receptors
-
Horn, F., Bettler, E., Oliveira, L., Campagne, F., Cohen, F.E. and Vriend, G. (2003) GPCRDB information system for G proteincoupled receptors. Nucleic Acids Res., 31, 294-297.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 294-297
-
-
Horn, F.1
Bettler, E.2
Oliveira, L.3
Campagne, F.4
Cohen, F.E.5
Vriend, G.6
-
7
-
-
0035170508
-
Collecting and harvesting biological data: The GPCRDB and NucleaRDB information systems
-
Horn, F., Vriend, G. and Cohen, F.E. (2001) Collecting and harvesting biological data: the GPCRDB and NucleaRDB information systems. Nucleic Acids Res., 29, 346-349.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 346-349
-
-
Horn, F.1
Vriend, G.2
Cohen, F.E.3
-
8
-
-
0031803634
-
GPCRDB: An information system for G protein-coupled receptors
-
Horn, F., Weare, J., Beukers, M.W., Horsch, S., Bairoch, A., Chen, W., Edvardsen, O., Campagne, F. and Vriend, G. (1998) GPCRDB: an information system for G protein-coupled receptors. Nucleic Acids Res., 26, 275-279.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 275-279
-
-
Horn, F.1
Weare, J.2
Beukers, M.W.3
Horsch, S.4
Bairoch, A.5
Chen, W.6
Edvardsen, O.7
Campagne, F.8
Vriend, G.9
-
9
-
-
80052603513
-
Integrating GPCR-specific information with full text articles
-
Vroling, B., Thorne, D., McDermott, P., Attwood, T.K., Vriend, G. and Pettifer, S. (2011) Integrating GPCR-specific information with full text articles. BMC Bioinformatics, 12, 362.
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 362
-
-
Vroling, B.1
Thorne, D.2
McDermott, P.3
Attwood, T.K.4
Vriend, G.5
Pettifer, S.6
-
10
-
-
80053297434
-
Snooker: A structure-based pharmacophore generation tool applied to class A GPCRs
-
Sanders, M.P., Verhoeven, S., de Graaf, C., Roumen, L., Vroling, B., Nabuurs, S.B., de Vlieg, J. and Klomp, J.P. (2011) Snooker: a structure-based pharmacophore generation tool applied to class A GPCRs. J. Chem. Inf. Model., 51, 2277-2292.
-
(2011)
J. Chem. Inf. Model.
, vol.51
, pp. 2277-2292
-
-
Sanders, M.P.1
Verhoeven, S.2
De Graaf, C.3
Roumen, L.4
Vroling, B.5
Nabuurs, S.B.6
De Vlieg, J.7
Klomp, J.P.8
-
11
-
-
80051521545
-
Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment
-
Kufareva, I., Rueda, M., Katritch, V., Stevens, R.C. and Abagyan, R. (2011) Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment. Structure, 19, 1108-1126.
-
(2011)
Structure
, vol.19
, pp. 1108-1126
-
-
Kufareva, I.1
Rueda, M.2
Katritch, V.3
Stevens, R.C.4
Abagyan, R.5
-
12
-
-
84857254248
-
Crystal structure of a lipid G protein-coupled receptor
-
Hanson, M.A., Roth, C.B., Jo, E., Griffith, M.T., Scott, F.L., Reinhart, G., Desale, H., Clemons, B., Cahalan, S.M., Schuerer, S.C. et al. (2012) Crystal structure of a lipid G protein-coupled receptor. Science, 335, 851-855.
-
(2012)
Science
, vol.335
, pp. 851-855
-
-
Hanson, M.A.1
Roth, C.B.2
Jo, E.3
Griffith, M.T.4
Scott, F.L.5
Reinhart, G.6
Desale, H.7
Clemons, B.8
Cahalan, S.M.9
Schuerer, S.C.10
-
13
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski, K., Kumasaka, T., Hori, T., Behnke, C.A., Motoshima, H., Fox, B.A., Le, T.I., Teller, D.C., Okada, T., Stenkamp, R.E. et al. (2000) Crystal structure of rhodopsin: a G protein-coupled receptor. Science, 289, 739-745.
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
Behnke, C.A.4
Motoshima, H.5
Fox, B.A.6
Le, T.I.7
Teller, D.C.8
Okada, T.9
Stenkamp, R.E.10
-
14
-
-
56749103466
-
The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist
-
Jaakola, V.-P., Griffith, M.T., Hanson, M.A., Cherezov, V., Chien, E.Y.T., Lane, J.R., Ijzerman, A.P. and Stevens, R.C. (2008) The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist. Science, 322, 1211-1217.
-
(2008)
Science
, vol.322
, pp. 1211-1217
-
-
Jaakola, V.-P.1
Griffith, M.T.2
Hanson, M.A.3
Cherezov, V.4
Chien, E.Y.T.5
Lane, J.R.6
Ijzerman, A.P.7
Stevens, R.C.8
-
15
-
-
78651277458
-
A series of PDB related databases for everyday needs
-
Joosten, R.P., te Beek, T.A., Krieger, E., Hekkelman, M.L., Hooft, R.W., Schneider, R., Sander, C. and Vriend, G. (2011) A series of PDB related databases for everyday needs. Nucleic Acids Res., 39, D411-D419.
-
(2011)
Nucleic Acids Res.
, vol.39
-
-
Joosten, R.P.1
Te Beek, T.A.2
Krieger, E.3
Hekkelman, M.L.4
Hooft, R.W.5
Schneider, R.6
Sander, C.7
Vriend, G.8
-
16
-
-
0037264352
-
Homology modeling
-
Krieger, E., Nabuurs, S.B. and Vriend, G. (2003) Homology modeling. Methods Biochem. Anal., 44, 509-523.
-
(2003)
Methods Biochem. Anal.
, vol.44
, pp. 509-523
-
-
Krieger, E.1
Nabuurs, S.B.2
Vriend, G.3
-
17
-
-
0001228323
-
A common motif in G-protein-coupled seven transmembrane helix receptors
-
Oliveira, L., Paiva, A.C.M. and Vriend, G. (1993) A common motif in G-protein-coupled seven transmembrane helix receptors. J. Comput. Aided Mol. Des., 7, 649-658.
-
(1993)
J. Comput. Aided Mol. Des.
, vol.7
, pp. 649-658
-
-
Oliveira, L.1
Paiva, A.C.M.2
Vriend, G.3
-
18
-
-
77957055780
-
Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein-coupled receptors
-
Ballesteros, J.A. and Weinstein, H. (1995) Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein-coupled receptors. Methods Neurosci., 25, 366-428.
-
(1995)
Methods Neurosci.
, vol.25
, pp. 366-428
-
-
Ballesteros, J.A.1
Weinstein, H.2
-
19
-
-
67650753759
-
Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design
-
Gloriam, D.E., Foord, S.M., Blaney, F.E. and Garland, S.L. (2009) Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design. J. Med. Chem., 52, 4429-4442.
-
(2009)
J. Med. Chem.
, vol.52
, pp. 4429-4442
-
-
Gloriam, D.E.1
Foord, S.M.2
Blaney, F.E.3
Garland, S.L.4
-
20
-
-
0000122573
-
PHYLIP-Phylogeny Inference Package (Version 3.2)
-
Felsenstein, J. (1989) PHYLIP-Phylogeny Inference Package (Version 3.2). Cladistics, 5, 164-166.
-
(1989)
Cladistics
, vol.5
, pp. 164-166
-
-
Felsenstein, J.1
-
21
-
-
79960617476
-
Methods for the successful application of chemogenomics to GPCR drug design
-
Garland, S. and Gloriam, D. (2011) Methods for the successful application of chemogenomics to GPCR drug design. Curr. Top. Med. Chem., 11, 1870-1871.
-
(2011)
Curr. Top. Med. Chem.
, vol.11
, pp. 1870-1871
-
-
Garland, S.1
Gloriam, D.2
|