Systematic identification of mutations that constitutively activate the angiotensin II type 1A receptor by screening a randomly mutated cDNA library with an original pharmacological bioassay

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 13, 2000, Pages 7615-7620

  Parnot, Charles ^a   Bardin, Sabine ^a   Miserey Lenkei, Stéphanie ^a   Guedin, Denis ^a,b   Corvol, Pierre ^a   Clauser, Eric ^a  

^a INSERM   (France)

^b SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AEQUORIN; ANGIOTENSIN; G PROTEIN COUPLED RECEPTOR; INOSITOL PHOSPHATE;

AMINO ACID SEQUENCE; ARTICLE; BRAIN MAPPING; CALCIUM MOBILIZATION; DNA LIBRARY; EUKARYOTE; GENE MUTATION; MEMBRANE POTENTIAL; MOLECULAR CLONING; MUTATION; PRIORITY JOURNAL; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS; THEORY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BIOLOGICAL ASSAY; CHO CELLS; CRICETINAE; GENE LIBRARY; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; RECEPTORS, ANGIOTENSIN; SIGNAL TRANSDUCTION;

EID: 0034691035     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.110142297     Document Type: Article

References (38)

1. Scheer, A. & Cotecchia, S. (1997) J. Recept. Signal Transduct. Res. 17, 57-73.
2. Cotecchia, S., Exum, S., Caron, M. G. & Lefkowitz, R. J. (1990) Proc. Natl. Acad. Sci. USA 87, 2896-2900.
3. Kjelsberg, M. A., Cotecchia, S., Ostrowski, J., Caron, M. G. & Lefkowitz, R. J. (1992) J. Biol. Chem. 267, 1430-1433.
4. Samama, P., Cotecchia, S., Costa, T. & Lefkowitz, R. J. (1993) J. Biol. Chem. 268, 4625-4636.
5. perez, D. M., Hwa, J., Gaivin, R., Mathur, M., Brown, F. & Graham, R. M. (1996) Mol. Pharmacol. 49, 112-122.
6. Dryja, T. P., Berson, E. L., Rao, V. R. & Oprian, D. D. (1993) Nat. Genet. 4, 280-283.
7. Shenker, A., Laue, L., Kosugi, S., Merendino, J. J., Jr., Minegishi, T. & Cutler, G. B., Jr. (1993) Nature (London) 365, 652-654.
8. Schipani, E., Kruse, K. & Juppner, H. (1995) Science 268, 98-100.
9. Parma, J., Duprez, L., Van Sande, J., Cochaux, P., Gervy, C., Mockel, J., Dumont, J. & Vassart, G. (1993) Nature (London) 365, 649-651.
10. Duprez, L., Parma, J., Van Sande, J., Allgeier, A., Leclerc, J., Schvartz, C., Delisle, M. J., Decoulx, M., Orgiazzi, J., Dumont, J., et al. (1994) Nat. Genet. 7, 396-401.
11. Bais, C., Santomasso, B., Coso, O., Arvanitakis, L., Raaka, E. G., Gutkind, J. S., Asch, A. S., Cesarman, E., Gershengorn, M. C., Mesri, E. A. & Gerhengorn, M. C. (1998) Nature (London) 391, 86-89.
12. Xie, J., Murone, M., Luoh, S. M., Ryan, A., Gu, Q., Zhang, C. Bonifas, J. M., Lam, C. W., Hynes, M., Goddard, A., et al. (1998) Nature (London) 391, 90-92.
13. Milano, C. A., Dolber, P. C., Rockman, H. A., Bond, R. A., Venable, M. E., Allen, L. F. & Lefkowitz, R. J. (1994) Proc. Natl. Acad. Sci. USA 91, 10109-10113.
14. Schipani, E., Lanske, B., Hunzelman, J., Luz, A., Kovacs, C. S., Lee, K., Pirro, A., Kronenberg, H. M. & Juppner, H. (1997) Proc. Natl. Acad. Sci. USA 94, 13689-13694.
15. Weiss, J. M., Morgan, P. H., Lutz, M. W. & Kenakin, T. P. (1996) J. Theor. Biol. 178, 151-167.
16. Weiss, J. M., Morgan, P. H., Lutz, M. W. & Kenakin, T. P. (1996) J. Theor. Biol. 178, 169-182.
17. Weiss, J. M., Morgan, P. H., Lutz, M. W. & Kenakin, T. P. (1996) J. Theor. Biol. 181, 381-397.
18. Chen, G., Way, J., Armour, S., Watson, C., Queen, K., Jayawickreme, C. K., Chen, W. J. & Kenakin, T. (2000) Mol. Pharmacol. 57, 125-134.
19. Groblewski, T., Maigret, B., Larguier, R., Lombard, C. Bonnafous, J. C. & Marie, J. (1997) J. Biol. Chem. 272, 1822-1826.
20. Feng, Y. H., Miura, S., Husain, A. & Karnik, S. S. (1998) Biochemistry 37, 15791-15798.
21. Miura, S., Feng, Y. H., Husain, A. & Karnik, S. S. (1999) J. Biol. Chem. 274, 7103-7110.
22. Balmforth, A. J., Lee, A. J., Warburton, P., Donnelly, D. & Ball, S. G. (1997) J. Biol. Chem. 272, 4245-4251.
23. Monnot, C., Bihoreau, C., Conchon, S., Curnow, K. M., Corvol, P. & Clauser, E. (1996) J. Biol. Chem. 271, 1507-1513.
24. Rizzuto, R., Simpson, A. W., Brini, M. & Pozzan, T. (1992) Nature (London) 358, 325-327.
25. Gossen, M. & Bujard, H. (1992) Proc. Natl. Acad. Sci. USA 89, 5547-5551.
26. Conchon, S., Monnot, C., Sirieix, M. E., Bihoreau, C., Corvol, P. & Clauser, E. (1994) Biochem. Biophys. Res. Commun. 199, 1347-1354.
27. Cadwell, R. C. & Joyce, G. F. (1992) PCR Methods Appl. 2, 28-33.
28. Parnot, C., Le Moullec, J. M., Cousin, M. A., Guedin, D., Corvol, P. & Pinet, F. (1997) Hypertension 30, 837-844.
29. Conchon, S., Barrault, M. B., Miserey, S., Corvol, P. & Clauser, E. (1997) J. Biol. Chem. 272, 25566-25572.
30. Burstein, E. S., Spalding, T. A., Brauner-Osborne, H. & Brann, M. R. (1995) FEBS Lett. 363, 261-263.
31. Brink, M. F., Nels, R. N., Verbeet, M. P. & de Boer, H. A. (1994) J. Mol. Biol. 237, 368-377.
32. Chen, K. & Arnold, F. H. (1993) Proc. Natl. Acad. Sci. USA 90, 5618-5622.
33. Crameri, A., Whitehorn, E. A., Tate, E. & Stemmer, W. P. (1996) Nat. Biotechnol. 14, 315-319.
34. Konopka, J. B., Margarit, S. M. & Dube, P. (1996) Proc. Natl. Acad. Sci. USA 93, 6764-6769.
35. Baranski, T. J., Herzmark, P., Lichtarge, O., Gerber, B. O., Trueheart, J., Meng, E. C., Iiri, T., Sheikh, S. P. & Bourne, H. R. (1999) J. Biol. Chem. 274, 15757-15765.
36. Kenakin, T. (1996) Pharmacol. Rev. 48, 413-463.
37. Duprez, L., Parma, J., Van Sande, J., Rodien, P., Sabine, C., Abramowicz, M., Dumont, J. E. & Vassart, G. (1999) J. Pediatr. Endocrinol. Metab. 12, Suppl. 1, 295-302.
38. Davies, E., Bonnardeaux, A., Plouin, P. F., Corvol, P. & Clauser, E. (1997) J. Clin. Endocrinol. Metab. 82, 611-615.