Parthenogenetic stem cells for tissue-engineered heart repair

Journal of Clinical Investigation

Volumn 123, Issue 3, 2013, Pages 1285-1298

  Didié, Michael ^a,b   Christalla, Peter ^a,b   Rubart, Michael ^c   Muppala, Vijayakumar ^a,b   Döker, Stephan ^a,b   Unsöld, Bernhard ^a,b   El Armouche, Ali ^a,b   Rau, Thomas ^b,d   Eschenhagen, Thomas ^b,d   Schwoerer, Alexander P ^b,d   Ehmke, Heimo ^b,d   Schumacher, Udo ^d   Fuchs, Sigrid ^d   Lange, Claudia ^d   Becker, Alexander ^a,b,c   Tao, Wen ^c   Scherschel, John A ^c   Soonpaa, Mark H ^c   Yang, Tao ^c   Lin, Qiong ^e   Zenke, Martin ^e   Han, Dong Wook ^f,g   Schöler, Hans R ^f   Rudolph, Cornelia ^h   Steinemann, Doris ^h   Schlegelberger, Brigitte ^h   Kattman, Steve ⁱ   Witty, Alec ⁱ   Keller, Gordon ⁱ   Field, Loren J ^c   Zimmermann, Wolfram Hubertus ^a,b   more..

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^e RWTH AACHEN UNIVERSITY   (Germany)

^f MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

^g Konkuk University School of Medicine   (South Korea)

^h HANNOVER MEDICAL SCHOOL   (Germany)

ⁱ UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN;

ALLOTRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL MATURATION; CELL SELECTION; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; EPIGENETICS; FEMALE; GENETIC VARIABILITY; HAPLOIDY; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE CELL; HEART SURGERY; HOMOZYGOSITY; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR IMPRINTING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARTHENOGENESIS; PARTHENOGENETIC STEM CELL; PRIORITY JOURNAL; STEM CELL; TISSUE ENGINEERING;

ACTION POTENTIALS; ANIMALS; ANTIGENS, DIFFERENTIATION; CALCIUM SIGNALING; CELL DIFFERENTIATION; CELL SHAPE; CELLS, CULTURED; EMBRYONIC STEM CELLS; EPIGENESIS, GENETIC; GENOTYPE; HEART; HISTOCOMPATIBILITY; HISTOCOMPATIBILITY ANTIGENS CLASS II; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, SCID; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; ORGAN CULTURE TECHNIQUES; ORGANOIDS; PARTHENOGENESIS; PHENOTYPE; STEM CELL TRANSPLANTATION; TISSUE ENGINEERING; TRANSPLANTATION, HOMOLOGOUS;

EID: 84874623698     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI66854     Document Type: Article

References (55)

1. Neaves WB, Baumann P. Unisexual reproduction among vertebrates. Trends Genet. 2011;27(3):81-88.
2. Surani MA, Barton SC, Norris ML. Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis. Nature. 1984;308(5959):548-550. (Pubitemid 14130845)
3. Brevini TA, Gandolfi F. Parthenotes as a source of embryonic stem cells. Cell Prolif. 2008; 41(suppl 1):20-30. (Pubitemid 350295854)
4. Linder D, McCaw BK, Hecht F. Parthenogenic origin of benign ovarian teratomas. N Engl J Med. 1975;292(2):63-66.
5. Cibelli JB, et al. Parthenogenetic stem cells in nonhuman primates. Science. 2002;295(5556):819. (Pubitemid 34118355)
6. Allen ND, Barton SC, Hilton K, Norris ML, Surani MA. A functional analysis of imprinting in parthenogenetic embryonic stem cells. Development. 1994;120(6):1473-1482. (Pubitemid 24175890)
7. Revazova ES, et al. Patient-specific stem cell lines derived from human parthenogenetic blastocysts. Cloning Stem Cells. 2007;9(3):432-449.
8. Lin G, et al. A highly homozygous and parthenogenetic human embryonic stem cell line derived from a one-pronuclear oocyte following in vitro fertilization procedure. Cell Res. 2007;17(12):999-1007. (Pubitemid 350261797)
9. Robertson EJ, Evans MJ, Kaufman MH. X-chromosome instability in pluripotential stem cell lines derived from parthenogenetic embryos. J Embryol Exp Morphol. 1983;74:297-309. (Pubitemid 13127153)
10. Chen Z, et al. Birth of parthenote mice directly from parthenogenetic embryonic stem cells. Stem Cells. 2009;27(9):2136-2145.
11. Fundele RH, et al. Temporal and spatial selection against parthenogenetic cells during development of fetal chimeras. Development. 1990;108(1):203-211.
12. Nagy A, Sass M, Markkula M. Systematic non-uniform distribution of parthenogenetic cells in adult mouse chimaeras. Development. 1989;106(2):321-324. (Pubitemid 19178968)
13. Spindle A, Sturm KS, Flannery M, Meneses JJ, Wu K, Pedersen RA. Defective chorioallantoic fusion in mid-gestation lethality of parthenogenone〈- 〉 tetraploid chimeras. Dev Biol. 1996;173(2):447-458.
14. Sturm KS, Flannery ML, Pedersen RA. Abnormal development of embryonic and extraembryonic cell lineages in parthenogenetic mouse embryos. Dev Dyn. 1994;201(1):11-28. (Pubitemid 24298168)
15. Vrana KE, et al. Nonhuman primate parthenogenetic stem cells. Proc Natl Acad Sci U S A. 2003; 100(suppl 1):11911-11916. (Pubitemid 37205903)
16. Laflamme MA, Murry CE. Heart regeneration. Nature. 2012;473(7347):326- 335.
17. Bühler K, et al. DIR Annual 2010. J Reproduktionsmed Endokrinol. 2011;8(4):253-280.
18. Mai Q, et al. Derivation of human embryonic stem cell lines from parthenogenetic blastocysts. Cell Res. 2007;17(12):1008-1019. (Pubitemid 350261798)
19. Kim K, et al. Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer. Cell Stem Cell. 2007;1(3):346-352. (Pubitemid 47355324)
20. Taylor CJ, Bolton EM, Pocock S, Sharples LD, Pedersen RA, Bradley JA. Banking on human embryonic stem cells: estimating the number of donor cell lines needed for HLA matching. Lancet. 2005; 366(9502):2019-2025. (Pubitemid 41773377)
21. Nakajima F, Tokunaga K, Nakatsuji N. Human leukocyte antigen matching estimations in a hypothetical bank of human embryonic stem cell lines in the Japanese population for use in cell transplantation therapy. Stem Cells. 2007;25(4):983-985. (Pubitemid 46572595)
22. Fernandes S, Kuklok S, McGonigle J, Reinecke H, Murry CE. Synthetic matrices to serve as niches for muscle cell transplantation. Cells Tissues Organs. 2012;195(1-2):48-59.
23. Zimmermann WH, et al. Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts. Nat Med. 2006;12(4):452-458.
24. Kattman SJ, et al. Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines. Cell Stem Cell. 2011;8(2):228-240.
25. Burridge PW, Keller G, Gold JD, Wu JC. Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming. Cell Stem Cell. 2012;10(1):16-28.
26. Klug MG, Soonpaa MH, Koh GY, Field LJ. Genetically selected cardiomyocytes from differentiating embryonic stem cells form stable intracardiac grafts. J Clin Invest. 1996;98(1):216-224. (Pubitemid 26243839)
27. Rubart M, Pasumarthi KB, Nakajima H, Soonpaa MH, Nakajima HO, Field LJ. Physiological coupling of donor and host cardiomyocytes after cellular transplantation. Circ Res. 2003;92(11):1217-1224. (Pubitemid 36723649)
28. Dubois NC, et al. SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells. Nat Biotechnol. 2011; 29(11):1011-1018.
29. Elliott DA, et al. NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes. Nat Methods. 2011;8(12):1037-1040.
30. Nagy A, Rossant J, Nagy R, Abramow-Newerly W, Roder JC. Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci U S A. 1993;90(18):8424-8428. (Pubitemid 23277681)
31. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006; 126(4):663-676. (Pubitemid 44233629)
32. Sharova LV, et al. Global gene expression profiling reveals similarities and differences among mouse pluripotent stem cells of different origins and strains. Dev Biol. 2007;307(2):446-459. (Pubitemid 47001365)
33. Kim K, et al. Histocompatible embryonic stem cells by parthenogenesis. Science. 2007; 315(5811):482-486. (Pubitemid 46178390)
34. Do JT, et al. Generation of parthenogenetic induced pluripotent stem cells from parthenogenetic neural stem cells. Stem Cells. 2009;27(12):2962-2968.
35. Mitalipov S, Clepper L, Sritanaudomchai H, Fujimoto A, Wolf D. Methylation status of imprinting centers for H19/IGF2 and SNURF/SNRPN in primate embryonic stem cells. Stem Cells. 2007; 25(3):581-588. (Pubitemid 46354216)
36. Boheler KR, Czyz J, Tweedie D, Yang HT, Anisimov SV, Wobus AM. Differentiation of pluripotent embryonic stem cells into cardiomyocytes. Circ Res. 2002;91(3):189-201. (Pubitemid 34875673)
37. Kehat I, et al. Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J Clin Invest. 2001;108(3):407-414. (Pubitemid 32730787)
38. Zwi L, et al. Cardiomyocyte differentiation of human induced pluripotent stem cells. Circulation. 2009; 120(15):1513-1523.
39. Mauritz C, et al. Generation of functional murine cardiac myocytes from induced pluripotent stem cells. Circulation. 2008;118(5):507-517.
40. Guan K, et al. Generation of functional cardiomyocytes from adult mouse spermatogonial stem cells. Circ Res. 2007;100(11):1615-1625. (Pubitemid 46897265)
41. Ieda M, et al. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell. 2010;142(3):375-386.
42. Qian L, et al. In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature. 2012;485(7400):593-598.
43. Song K, et al. Heart repair by reprogramming nonmyocytes with cardiac transcription factors. Nature. 2012;485(7400):599-604.
44. Schwartz SD, et al. Embryonic stem cell trials for macular degeneration: a preliminary report. Lancet. 2012;379(9817):713-720.
45. Zimmermann WH. Embryonic and embryonic-like stem cells in heart muscle engineering. J Mol Cell Cardiol. 2011;50(2):320-326.
46. van Laake LW, et al. Extracellular matrix formation after transplantation of human embryonic stem cell-derived cardiomyocytes. Cell Mol Life Sci. 2010;67(2):277-290.
47. Kehat I, et al. Electromechanical integration of cardiomyocytes derived from human embryonic stem cells. Nat Biotechnol. 2004;22(10):1282-1289. (Pubitemid 39341201)
48. Shiba Y, et al. Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts. Nature. 2012;489(7415):322-325.
49. Zimmermann WH, et al. Tissue engineering of a differentiated cardiac muscle construct. Circ Res. 2002; 90(2):223-230.
50. Streckfuss-Bomeke K, et al. Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts [published online ahead of print July 12, 2012]. Eur Heart J. doi:10.1093/eurheartj/ehs203.
51. Soong PL, Tiburcy M, Zimmermann WH. Cardiac differentiation of human embryonic stem cells and their assembly into engineered heart muscle. Curr Protoc Cell Biol. 2012;Chapter 23:Unit23.8.
52. Wobus AM, Wallukat G, Hescheler J. Pluripotent mouse embryonic stem cells are able to differentiate into cardiomyocytes expressing chronotropic responses to adrenergic and cholinergic agents and Ca2+ channel blockers. Differentiation. 1991; 48(3):173-182.
53. Irizarry RA, et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics. 2003;4(2):249-264.
54. Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Roy Statist Soc Ser B. 1995;57:289-300.
55. Guan K, et al. Pluripotency of spermatogonial stem cells from adult mouse testis. Nature. 2006; 440(7088):1199-1203.