메뉴 건너뛰기




Volumn 8, Issue 8, 2013, Pages

Increased Cellular Senescence and Vascular Rarefaction Exacerbate the Progression of Kidney Fibrosis in Aged Mice Following Transient Ischemic Injury

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; COLLAGEN TYPE 3; COLLAGEN TYPE 4; CREATININE; FIBRONECTIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN P21; PROTEIN P53; TUMOR NECROSIS FACTOR ALPHA;

EID: 84881113183     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070464     Document Type: Article
Times cited : (106)

References (51)
  • 1
    • 33644874086 scopus 로고    scopus 로고
    • Acute kidney injury, mortality, length of stay, and costs in hospitalized patients
    • Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW, (2005) Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol 16: 3365-3370.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3365-3370
    • Chertow, G.M.1    Burdick, E.2    Honour, M.3    Bonventre, J.V.4    Bates, D.W.5
  • 2
    • 79953175649 scopus 로고    scopus 로고
    • Pathophysiology of ischemic acute kidney injury
    • Sharfuddin AA, Molitoris BA, (2011) Pathophysiology of ischemic acute kidney injury. Nat Rev Nephrol 7: 189-200.
    • (2011) Nat Rev Nephrol , vol.7 , pp. 189-200
    • Sharfuddin, A.A.1    Molitoris, B.A.2
  • 3
    • 47149094501 scopus 로고    scopus 로고
    • Recovery of kidney function after acute kidney injury in the elderly: a systematic review and meta-analysis
    • Schmitt R, Coca S, Kanbay M, Tinetti ME, Cantley LG, et al. (2008) Recovery of kidney function after acute kidney injury in the elderly: a systematic review and meta-analysis. Am J Kidney Dis 52: 262-271.
    • (2008) Am J Kidney Dis , vol.52 , pp. 262-271
    • Schmitt, R.1    Coca, S.2    Kanbay, M.3    Tinetti, M.E.4    Cantley, L.G.5
  • 4
    • 57149105572 scopus 로고    scopus 로고
    • Zag expression during aging suppresses proliferation after kidney injury
    • Schmitt R, Marlier A, Cantley LG, (2008) Zag expression during aging suppresses proliferation after kidney injury. J Am Soc Nephrol 19: 2375-2383.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 2375-2383
    • Schmitt, R.1    Marlier, A.2    Cantley, L.G.3
  • 5
    • 78751636310 scopus 로고    scopus 로고
    • System URD, Bethesda: National Institutes of Health, national Institute of Diabetes and Digestive and Kidney Diseases
    • System URD (2010) USRDS 2010 Annual Data Report. Bethesda: National Institutes of Health, national Institute of Diabetes and Digestive and Kidney Diseases.
    • (2010) USRDS 2010 Annual Data Report
  • 6
    • 72949089927 scopus 로고    scopus 로고
    • Experimental ischemia-reperfusion: biases and myths-the proximal vs. distal hypoxic tubular injury debate revisited
    • Heyman SN, Rosenberger C, Rosen S, (2010) Experimental ischemia-reperfusion: biases and myths-the proximal vs. distal hypoxic tubular injury debate revisited. Kidney Int 77: 9-16.
    • (2010) Kidney Int , vol.77 , pp. 9-16
    • Heyman, S.N.1    Rosenberger, C.2    Rosen, S.3
  • 7
    • 0033970202 scopus 로고    scopus 로고
    • Acute renal failure. II. Experimental models of acute renal failure: imperfect but indispensable
    • Lieberthal W, Nigam SK, (2000) Acute renal failure. II. Experimental models of acute renal failure: imperfect but indispensable. Am J Physiol Renal Physiol 278: F1-F12.
    • (2000) Am J Physiol Renal Physiol , vol.278
    • Lieberthal, W.1    Nigam, S.K.2
  • 8
    • 33947663090 scopus 로고    scopus 로고
    • Long-term outcome of acute tubular necrosis: a contribution to its natural history
    • Liano F, Felipe C, Tenorio MT, Rivera M, Abraira V, et al. (2007) Long-term outcome of acute tubular necrosis: a contribution to its natural history. Kidney Int 71: 679-686.
    • (2007) Kidney Int , vol.71 , pp. 679-686
    • Liano, F.1    Felipe, C.2    Tenorio, M.T.3    Rivera, M.4    Abraira, V.5
  • 9
    • 0037836057 scopus 로고    scopus 로고
    • Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure
    • Bonventre JV, (2003) Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure. J Am Soc Nephrol 14Suppl 1: S55-61.
    • (2003) J Am Soc Nephrol , vol.14
    • Bonventre, J.V.1
  • 12
    • 77952174830 scopus 로고    scopus 로고
    • Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
    • Yang L, Besschetnova TY, Brooks CR, Shah JV, Bonventre JV, (2010) Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nat Med 16: 535-543.
    • (2010) Nat Med , vol.16 , pp. 535-543
    • Yang, L.1    Besschetnova, T.Y.2    Brooks, C.R.3    Shah, J.V.4    Bonventre, J.V.5
  • 13
    • 35348923554 scopus 로고    scopus 로고
    • Increased susceptibility of aging kidney to ischemic injury: identification of candidate genes changed during aging, but corrected by caloric restriction
    • Chen G, Bridenbaugh EA, Akintola AD, Catania JM, Vaidya VS, et al. (2007) Increased susceptibility of aging kidney to ischemic injury: identification of candidate genes changed during aging, but corrected by caloric restriction. Am J Physiol Renal Physiol 293: F1272-1281.
    • (2007) Am J Physiol Renal Physiol , vol.293
    • Chen, G.1    Bridenbaugh, E.A.2    Akintola, A.D.3    Catania, J.M.4    Vaidya, V.S.5
  • 14
    • 0036710467 scopus 로고    scopus 로고
    • Age-related decline in cellular response to oxidative stress: links to growth factor signaling pathways with common defects
    • Holbrook NJ, Ikeyama S, (2002) Age-related decline in cellular response to oxidative stress: links to growth factor signaling pathways with common defects. Biochem Pharmacol 64: 999-1005.
    • (2002) Biochem Pharmacol , vol.64 , pp. 999-1005
    • Holbrook, N.J.1    Ikeyama, S.2
  • 16
    • 77449114064 scopus 로고    scopus 로고
    • The pathogenesis of susceptibility to acute kidney injury in the elderly
    • Rosner MH, (2009) The pathogenesis of susceptibility to acute kidney injury in the elderly. Curr Aging Sci 2: 158-164.
    • (2009) Curr Aging Sci , vol.2 , pp. 158-164
    • Rosner, M.H.1
  • 18
    • 79954592623 scopus 로고    scopus 로고
    • The induction of macrophage hemeoxygenase-1 is protective during acute kidney injury in aging mice
    • Ferenbach DA, Nkejabega NC, McKay J, Choudhary AK, Vernon MA, et al. (2011) The induction of macrophage hemeoxygenase-1 is protective during acute kidney injury in aging mice. Kidney Int 79: 966-976.
    • (2011) Kidney Int , vol.79 , pp. 966-976
    • Ferenbach, D.A.1    Nkejabega, N.C.2    McKay, J.3    Choudhary, A.K.4    Vernon, M.A.5
  • 19
    • 0031668169 scopus 로고    scopus 로고
    • Polarity, integrin, and extracellular matrix dynamics in the postischemic rat kidney
    • Zuk A, Bonventre JV, Brown D, Matlin KS, (1998) Polarity, integrin, and extracellular matrix dynamics in the postischemic rat kidney. Am J Physiol 275: C711-731.
    • (1998) Am J Physiol , vol.275
    • Zuk, A.1    Bonventre, J.V.2    Brown, D.3    Matlin, K.S.4
  • 20
    • 0017704925 scopus 로고
    • Studies of cellular recovery from injury. III. Ultrastructural studies on the recovery of the pars recta of the proximal tubule (P3 segment) of the rat kidney from temporary ischemia
    • Glaumann B, Glaumann H, Trump BF, (1977) Studies of cellular recovery from injury. III. Ultrastructural studies on the recovery of the pars recta of the proximal tubule (P3 segment) of the rat kidney from temporary ischemia. Virchows Arch B Cell Pathol 25: 281-308.
    • (1977) Virchows Arch B Cell Pathol , vol.25 , pp. 281-308
    • Glaumann, B.1    Glaumann, H.2    Trump, B.F.3
  • 21
    • 0018142634 scopus 로고
    • Ischemic damage and repair in the rat proximal tubule: differences among the S1, S2, and S3 segments
    • Venkatachalam MA, Bernard DB, Donohoe JF, Levinsky NG, (1978) Ischemic damage and repair in the rat proximal tubule: differences among the S1, S2, and S3 segments. Kidney Int 14: 31-49.
    • (1978) Kidney Int , vol.14 , pp. 31-49
    • Venkatachalam, M.A.1    Bernard, D.B.2    Donohoe, J.F.3    Levinsky, N.G.4
  • 22
    • 0030419494 scopus 로고    scopus 로고
    • Molecular insights into renal interstitial fibrosis
    • Eddy AA, (1996) Molecular insights into renal interstitial fibrosis. J Am Soc Nephrol 7: 2495-2508.
    • (1996) J Am Soc Nephrol , vol.7 , pp. 2495-2508
    • Eddy, A.A.1
  • 24
    • 0029047362 scopus 로고
    • A biomarker that identifies senescent human cells in culture and in aging skin in vivo
    • Dimri GP, Lee X, Basile G, Acosta M, Scott G, et al. (1995) A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A 92: 9363-9367.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 9363-9367
    • Dimri, G.P.1    Lee, X.2    Basile, G.3    Acosta, M.4    Scott, G.5
  • 25
    • 78349295987 scopus 로고    scopus 로고
    • Senescence and dysfunction of proximal tubular cells are associated with activated p53 expression by indoxyl sulfate
    • Shimizu H, Bolati D, Adijiang A, Enomoto A, Nishijima F, et al. (2010) Senescence and dysfunction of proximal tubular cells are associated with activated p53 expression by indoxyl sulfate. Am J Physiol Cell Physiol 299: C1110-1117.
    • (2010) Am J Physiol Cell Physiol , vol.299
    • Shimizu, H.1    Bolati, D.2    Adijiang, A.3    Enomoto, A.4    Nishijima, F.5
  • 26
    • 60749095669 scopus 로고    scopus 로고
    • Renal ischemia-reperfusion leads to long term infiltration of activated and effector-memory T lymphocytes
    • Ascon M, Ascon DB, Liu M, Cheadle C, Sarkar C, et al. (2009) Renal ischemia-reperfusion leads to long term infiltration of activated and effector-memory T lymphocytes. Kidney Int 75: 526-535.
    • (2009) Kidney Int , vol.75 , pp. 526-535
    • Ascon, M.1    Ascon, D.B.2    Liu, M.3    Cheadle, C.4    Sarkar, C.5
  • 27
    • 42449105787 scopus 로고    scopus 로고
    • Macrophages contribute to the development of renal fibrosis following ischaemia/reperfusion-induced acute kidney injury
    • Ko GJ, Boo CS, Jo SK, Cho WY, Kim HK, (2008) Macrophages contribute to the development of renal fibrosis following ischaemia/reperfusion-induced acute kidney injury. Nephrol Dial Transplant 23: 842-852.
    • (2008) Nephrol Dial Transplant , vol.23 , pp. 842-852
    • Ko, G.J.1    Boo, C.S.2    Jo, S.K.3    Cho, W.Y.4    Kim, H.K.5
  • 28
    • 0035199934 scopus 로고    scopus 로고
    • Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function
    • Basile DP, Donohoe D, Roethe K, Osborn JL, (2001) Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function. Am J Physiol Renal Physiol 281: F887-899.
    • (2001) Am J Physiol Renal Physiol , vol.281
    • Basile, D.P.1    Donohoe, D.2    Roethe, K.3    Osborn, J.L.4
  • 29
    • 34548647550 scopus 로고    scopus 로고
    • Acute and chronic microvascular alterations in a mouse model of ischemic acute kidney injury
    • Horbelt M, Lee SY, Mang HE, Knipe NL, Sado Y, et al. (2007) Acute and chronic microvascular alterations in a mouse model of ischemic acute kidney injury. Am J Physiol Renal Physiol 293: F688-695.
    • (2007) Am J Physiol Renal Physiol , vol.293
    • Horbelt, M.1    Lee, S.Y.2    Mang, H.E.3    Knipe, N.L.4    Sado, Y.5
  • 30
    • 26244454791 scopus 로고    scopus 로고
    • Oxidative stress promotes endothelial cell apoptosis and loss of microvessels in the spontaneously hypertensive rats
    • Kobayashi N, DeLano FA, Schmid-Schonbein GW, (2005) Oxidative stress promotes endothelial cell apoptosis and loss of microvessels in the spontaneously hypertensive rats. Arterioscler Thromb Vasc Biol 25: 2114-2121.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2114-2121
    • Kobayashi, N.1    DeLano, F.A.2    Schmid-Schonbein, G.W.3
  • 31
    • 68049112547 scopus 로고    scopus 로고
    • Reactive oxygen species/oxidative stress contributes to progression of kidney fibrosis following transient ischemic injury in mice
    • Kim J, Seok YM, Jung KJ, Park KM, (2009) Reactive oxygen species/oxidative stress contributes to progression of kidney fibrosis following transient ischemic injury in mice. Am J Physiol Renal Physiol 297: F461-470.
    • (2009) Am J Physiol Renal Physiol , vol.297
    • Kim, J.1    Seok, Y.M.2    Jung, K.J.3    Park, K.M.4
  • 32
    • 33748431953 scopus 로고    scopus 로고
    • Mortality after acute renal failure: models for prognostic stratification and risk adjustment
    • Chertow GM, Soroko SH, Paganini EP, Cho KC, Himmelfarb J, et al. (2006) Mortality after acute renal failure: models for prognostic stratification and risk adjustment. Kidney Int 70: 1120-1126.
    • (2006) Kidney Int , vol.70 , pp. 1120-1126
    • Chertow, G.M.1    Soroko, S.H.2    Paganini, E.P.3    Cho, K.C.4    Himmelfarb, J.5
  • 34
    • 82955223260 scopus 로고    scopus 로고
    • Age-dependent responses to renal ischemia-reperfusion injury
    • Kusaka J, Koga H, Hagiwara S, Hasegawa A, Kudo K, et al. (2012) Age-dependent responses to renal ischemia-reperfusion injury. J Surg Res 172: 153-158.
    • (2012) J Surg Res , vol.172 , pp. 153-158
    • Kusaka, J.1    Koga, H.2    Hagiwara, S.3    Hasegawa, A.4    Kudo, K.5
  • 37
    • 44949153476 scopus 로고    scopus 로고
    • Long-term outcomes of acute kidney injury
    • Goldberg R, Dennen P, (2008) Long-term outcomes of acute kidney injury. Adv Chronic Kidney Dis 15: 297-307.
    • (2008) Adv Chronic Kidney Dis , vol.15 , pp. 297-307
    • Goldberg, R.1    Dennen, P.2
  • 38
    • 79960882488 scopus 로고    scopus 로고
    • Replicative senescence in kidney aging, renal disease, and renal transplantation
    • Naesens M, (2011) Replicative senescence in kidney aging, renal disease, and renal transplantation. Discov Med 11: 65-75.
    • (2011) Discov Med , vol.11 , pp. 65-75
    • Naesens, M.1
  • 39
    • 77956534990 scopus 로고    scopus 로고
    • Cell senescence in the aging kidney
    • Yang H, Fogo AB, (2010) Cell senescence in the aging kidney. J Am Soc Nephrol 21: 1436-1439.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1436-1439
    • Yang, H.1    Fogo, A.B.2
  • 41
    • 77952105389 scopus 로고    scopus 로고
    • Inflammatory networks during cellular senescence: causes and consequences
    • Freund A, Orjalo AV, Desprez PY, Campisi J, (2010) Inflammatory networks during cellular senescence: causes and consequences. Trends Mol Med 16: 238-246.
    • (2010) Trends Mol Med , vol.16 , pp. 238-246
    • Freund, A.1    Orjalo, A.V.2    Desprez, P.Y.3    Campisi, J.4
  • 42
    • 33645525811 scopus 로고    scopus 로고
    • The relationship between albuminuria, MCP-1/CCL2, and interstitial macrophages in chronic kidney disease
    • Eardley KS, Zehnder D, Quinkler M, Lepenies J, Bates RL, et al. (2006) The relationship between albuminuria, MCP-1/CCL2, and interstitial macrophages in chronic kidney disease. Kidney Int 69: 1189-1197.
    • (2006) Kidney Int , vol.69 , pp. 1189-1197
    • Eardley, K.S.1    Zehnder, D.2    Quinkler, M.3    Lepenies, J.4    Bates, R.L.5
  • 43
    • 59449085356 scopus 로고    scopus 로고
    • Chemokine/chemokine receptor-mediated inflammation regulates pathologic changes from acute kidney injury to chronic kidney disease
    • Furuichi K, Kaneko S, Wada T, (2009) Chemokine/chemokine receptor-mediated inflammation regulates pathologic changes from acute kidney injury to chronic kidney disease. Clin Exp Nephrol 13: 9-14.
    • (2009) Clin Exp Nephrol , vol.13 , pp. 9-14
    • Furuichi, K.1    Kaneko, S.2    Wada, T.3
  • 44
    • 0029945622 scopus 로고    scopus 로고
    • Mechanisms involved in the pathogenesis of tubulointerstitial fibrosis in 5/6-nephrectomized rats
    • Kliem V, Johnson RJ, Alpers CE, Yoshimura A, Couser WG, et al. (1996) Mechanisms involved in the pathogenesis of tubulointerstitial fibrosis in 5/6-nephrectomized rats. Kidney Int 49: 666-678.
    • (1996) Kidney Int , vol.49 , pp. 666-678
    • Kliem, V.1    Johnson, R.J.2    Alpers, C.E.3    Yoshimura, A.4    Couser, W.G.5
  • 45
    • 69449106763 scopus 로고    scopus 로고
    • Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats
    • Schaier M, Vorwalder S, Sommerer C, Dikow R, Hug F, et al. (2009) Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats. Am J Physiol Renal Physiol 297: F769-780.
    • (2009) Am J Physiol Renal Physiol , vol.297
    • Schaier, M.1    Vorwalder, S.2    Sommerer, C.3    Dikow, R.4    Hug, F.5
  • 46
    • 77955174530 scopus 로고    scopus 로고
    • Pivotal role of CD4(+) T cells in renal fibrosis following ureteric obstruction
    • Tapmeier TT, Fearn A, Brown K, Chowdhury P, Sacks SH, et al. (2010) Pivotal role of CD4(+) T cells in renal fibrosis following ureteric obstruction. Kidney Int 78: 351-362.
    • (2010) Kidney Int , vol.78 , pp. 351-362
    • Tapmeier, T.T.1    Fearn, A.2    Brown, K.3    Chowdhury, P.4    Sacks, S.H.5
  • 47
    • 55849103960 scopus 로고    scopus 로고
    • Macrophage diversity in renal injury and repair
    • Ricardo SD, van Goor H, Eddy AA, (2008) Macrophage diversity in renal injury and repair. J Clin Invest 118: 3522-3530.
    • (2008) J Clin Invest , vol.118 , pp. 3522-3530
    • Ricardo, S.D.1    van Goor, H.2    Eddy, A.A.3
  • 48
    • 84881110633 scopus 로고    scopus 로고
    • Inhibition of the c-fms receptor prevents kidney macrophage accumulation and is renoprotective following ischemic injury [Abstract]
    • Clements M, Gershenovich M, Chaber C, Ledbetter S, Zuk A (2011) Inhibition of the c-fms receptor prevents kidney macrophage accumulation and is renoprotective following ischemic injury [Abstract]. J Am Soc Nephrol 22.
    • (2011) J Am Soc Nephrol , vol.22
    • Clements, M.1    Gershenovich, M.2    Chaber, C.3    Ledbetter, S.4    Zuk, A.5
  • 49
    • 59249107409 scopus 로고    scopus 로고
    • Decreased vascular repair and neovascularization with ageing: mechanisms and clinical relevance with an emphasis on hypoxia-inducible factor-1
    • Hoenig MR, Bianchi C, Rosenzweig A, Sellke FW, (2008) Decreased vascular repair and neovascularization with ageing: mechanisms and clinical relevance with an emphasis on hypoxia-inducible factor-1. Curr Mol Med 8: 754-767.
    • (2008) Curr Mol Med , vol.8 , pp. 754-767
    • Hoenig, M.R.1    Bianchi, C.2    Rosenzweig, A.3    Sellke, F.W.4
  • 50
    • 0035124069 scopus 로고    scopus 로고
    • Impaired angiogenesis in the aging kidney: vascular endothelial growth factor and thrombospondin-1 in renal disease
    • Kang DH, Anderson S, Kim YG, Mazzalli M, Suga S, et al. (2001) Impaired angiogenesis in the aging kidney: vascular endothelial growth factor and thrombospondin-1 in renal disease. Am J Kidney Dis 37: 601-611.
    • (2001) Am J Kidney Dis , vol.37 , pp. 601-611
    • Kang, D.H.1    Anderson, S.2    Kim, Y.G.3    Mazzalli, M.4    Suga, S.5
  • 51
    • 62349127883 scopus 로고    scopus 로고
    • Development and validation of an acute kidney injury risk index for patients undergoing general surgery: results from a national data set
    • Kheterpal S, Tremper KK, Heung M, Rosenberg AL, Englesbe M, et al. (2009) Development and validation of an acute kidney injury risk index for patients undergoing general surgery: results from a national data set. Anesthesiology 110: 505-515.
    • (2009) Anesthesiology , vol.110 , pp. 505-515
    • Kheterpal, S.1    Tremper, K.K.2    Heung, M.3    Rosenberg, A.L.4    Englesbe, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.