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Volumn 31, Issue 4, 1999, Pages 773-783

Pentoxifylline inhibits PDGF-induced proliferation of and TGF-β-stimulated collagen synthesis by vascular smooth muscle cells

Author keywords

Collagen; Pentoxifylline; Proliferation; Vascular smooth muscle cell

Indexed keywords

ANTIMITOTIC AGENT; BUCLADESINE; COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC GMP; MESSENGER RNA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NONAPEPTIDE; PENTOXIFYLLINE; PLATELET DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 0033119248     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1998.0910     Document Type: Article
Times cited : (55)

References (40)
  • 1
    • 0025800329 scopus 로고
    • Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle ells
    • AMENTO EP, EHSANI N, PALMER H, LIBBY P, 1991. Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle ells. Atherosclerosis Throm 11: 1223-1230.
    • (1991) Atherosclerosis Throm , vol.11 , pp. 1223-1230
    • Amento, E.P.1    Ehsani, N.2    Palmer, H.3    Libby, P.4
  • 4
    • 0024514942 scopus 로고
    • Pentoxifylline inhibits normal human dermal fibroblast in vitro proliferation, collagen, glycosaminoglycan, and fibronectin production, and increases collagenase activity
    • BERMAN B, MATTHEW R, DUNCAN MR, 1989. Pentoxifylline inhibits normal human dermal fibroblast in vitro proliferation, collagen, glycosaminoglycan, and fibronectin production, and increases collagenase activity. J Invest Dermatol 92: 605-610.
    • (1989) J Invest Dermatol , vol.92 , pp. 605-610
    • Berman, B.1    Matthew, R.2    Duncan, M.R.3
  • 5
    • 0026757051 scopus 로고
    • Activation of MAP kinases by calcium-dependent and calcium-independent pathways. Stimulation by thapsigargin and epidermal growth factor
    • CHAO T-SO, BYRON KL, LEE K-M, VILLEREAL M, ROSNER MR, 1992. Activation of MAP kinases by calcium-dependent and calcium-independent pathways. Stimulation by thapsigargin and epidermal growth factor. J Biol Chem 267: 19876-19883.
    • (1992) J Biol Chem , vol.267 , pp. 19876-19883
    • Chao, T.-S.O.1    Byron, K.L.2    Lee, K.-M.3    Villereal, M.4    Rosner, M.R.5
  • 6
    • 0025248571 scopus 로고
    • Inhibitor of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-bromocinnamyl (amino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma
    • CHIJIWA T, MISHIMA A, HAGIWARA M, SANO M, HAYASHI K, INOUE T, NAITO K, TOSHIOKA T, HIDAKA H, 1990. Inhibitor of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-bromocinnamyl (amino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma. J Biol Chem 265: 5267-5272.
    • (1990) J Biol Chem , vol.265 , pp. 5267-5272
    • Chijiwa, T.1    Mishima, A.2    Hagiwara, M.3    Sano, M.4    Hayashi, K.5    Inoue, T.6    Naito, K.7    Toshioka, T.8    Hidaka, H.9
  • 7
    • 0020502095 scopus 로고
    • Mechanisms of stenosis after arterial injury
    • CLOWES AW, REIDY MA, CLOWES MM, 1983. Mechanisms of stenosis after arterial injury. Lab Invest 49: 208-215.
    • (1983) Lab Invest , vol.49 , pp. 208-215
    • Clowes, A.W.1    Reidy, M.A.2    Clowes, M.M.3
  • 8
    • 0028801716 scopus 로고
    • Pentoxifylline, pentifylline, and interferons decrease type I and III procollagen mRNA levels in dermal fibroblasts: Evidence for mediation by nuclear factor 1 down-regulation
    • DUNCAN MR, HASAN A, BERMAN B, 1995. Pentoxifylline, pentifylline, and interferons decrease type I and III procollagen mRNA levels in dermal fibroblasts: evidence for mediation by nuclear factor 1 down-regulation. J Invest Dermatol 104: 282-286.
    • (1995) J Invest Dermatol , vol.104 , pp. 282-286
    • Duncan, M.R.1    Hasan, A.2    Berman, B.3
  • 10
    • 0026418308 scopus 로고
    • Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF
    • FERNS GAA, RAINES EW, SPRUGEL KH, MOTANI AS, REIDY MA, ROSS R, 1991. Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF. Science 253: 1129-1132.
    • (1991) Science , vol.253 , pp. 1129-1132
    • Ferns, G.A.A.1    Raines, E.W.2    Sprugel, K.H.3    Motani, A.S.4    Reidy, M.A.5    Ross, R.6
  • 11
    • 0029552361 scopus 로고
    • Pentoxifylline and intermittent claudication: Review of clinical trials and cost-effectiveness analyses
    • GILLINGS DB, 1995. Pentoxifylline and intermittent claudication: review of clinical trials and cost-effectiveness analyses. J Cardiovasc Pharmacol 25 [Suppl 2]: S44-S50.
    • (1995) J Cardiovasc Pharmacol , vol.25 , Issue.SUPPL. 2
    • Gillings, D.B.1
  • 12
    • 0024353865 scopus 로고
    • Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein
    • GLASS DB, CHEN H-C, MENDE-MUELLER L, REED J, WALSH DA, 1989. Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein. J Biol Chem 264: 8802-8810.
    • (1989) J Biol Chem , vol.264 , pp. 8802-8810
    • Glass, D.B.1    Chen, H.-C.2    Mende-Mueller, L.3    Reed, J.4    Walsh, D.A.5
  • 13
    • 0026062120 scopus 로고
    • Platelet-derived growth factor activity and mRNA expression in healing vascular grafts in baboons. Association in vivo of platelet-derived growth factor mRNA and protein with cellular proliferation
    • GOLDEN MA, AU YPT, KIRKMAN TR, WILCOX JN, RAINES EW, ROSS R, CLOWES AW, 1991. Platelet-derived growth factor activity and mRNA expression in healing vascular grafts in baboons. Association in vivo of platelet-derived growth factor mRNA and protein with cellular proliferation. J Clin Invest 87: 406-414.
    • (1991) J Clin Invest , vol.87 , pp. 406-414
    • Golden, M.A.1    Au, Y.P.T.2    Kirkman, T.R.3    Wilcox, J.N.4    Raines, E.W.5    Ross, R.6    Clowes, A.W.7
  • 14
    • 0027374550 scopus 로고
    • Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells
    • GRAVES LM, BORNFELDT KE, RAINES EW, POTTS BC, MACDONALD SG, ROSS R, KREBS EG, 1993. Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells. Proc Natl Acad Sci USA 90: 10300-10304.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10300-10304
    • Graves, L.M.1    Bornfeldt, K.E.2    Raines, E.W.3    Potts, B.C.4    MacDonald, S.G.5    Ross, R.6    Krebs, E.G.7
  • 15
    • 0030582462 scopus 로고    scopus 로고
    • Interactions between cAMP- and cGMP-dependent protein kinase inhibitors and phosphodiesterase IV inhibitors on arachidonate release from human monocytes
    • HICHAMI A, BIOCHOT E, GERMAIN N, COQUERET O, LAGENTE V, 1996. Interactions between cAMP-and cGMP-dependent protein kinase inhibitors and phosphodiesterase IV inhibitors on arachidonate release from human monocytes. Life Sci 59: 255-261.
    • (1996) Life Sci , vol.59 , pp. 255-261
    • Hichami, A.1    Biochot, E.2    Germain, N.3    Coqueret, O.4    Lagente, V.5
  • 16
    • 0017128325 scopus 로고
    • Bioavailability and pharmacokinetics of pentoxifylline and Trental 400 in man
    • HINZE JH, GRIGOLEIT HG, RETHY B, 1976. Bioavailability and pharmacokinetics of pentoxifylline and Trental 400 in man. Pharmatherapeutica 1: 160-171.
    • (1976) Pharmatherapeutica , vol.1 , pp. 160-171
    • Hinze, J.H.1    Grigoleit, H.G.2    Rethy, B.3
  • 17
    • 0031930455 scopus 로고    scopus 로고
    • Platelet-derived growth factor and pentoxifylline modulation of collagen synthesis in myofibroblasts
    • ISBRUCKER RA, PETERSON TC, 1998. Platelet-derived growth factor and pentoxifylline modulation of collagen synthesis in myofibroblasts. Toxicol Appl Pharmacol 149: 120-126.
    • (1998) Toxicol Appl Pharmacol , vol.149 , pp. 120-126
    • Isbrucker, R.A.1    Peterson, T.C.2
  • 18
    • 0026495734 scopus 로고
    • Pharmacology of smooth muscle cell replication
    • JACKSON CL, SCHWARTZ SM, 1992. Pharmacology of smooth muscle cell replication. Hypertension 20: 713-736.
    • (1992) Hypertension , vol.20 , pp. 713-736
    • Jackson, C.L.1    Schwartz, S.M.2
  • 19
    • 0027261204 scopus 로고
    • Role of endogenous platelet-derived growth factor in arterial smooth muscle cell migration after balloon catheter injury
    • JACKSON CL, RAINES EW, ROSS R, REIDY MA, 1993. Role of endogenous platelet-derived growth factor in arterial smooth muscle cell migration after balloon catheter injury. Arteriosclerosis Throm 13: 1218-1226.
    • (1993) Arteriosclerosis Throm , vol.13 , pp. 1218-1226
    • Jackson, C.L.1    Raines, E.W.2    Ross, R.3    Reidy, M.A.4
  • 20
    • 0023762188 scopus 로고
    • Serum deprivation of vascular smooth muscle cells enhances collagen gene expression
    • KINDY MS, CHANG C-J, SONENSHEIN GE, 1988. Serum deprivation of vascular smooth muscle cells enhances collagen gene expression. J Biol Chem 263: 11426-11430.
    • (1988) J Biol Chem , vol.263 , pp. 11426-11430
    • Kindy, M.S.1    Chang, C.-J.2    Sonenshein, G.E.3
  • 21
    • 0030921717 scopus 로고    scopus 로고
    • Cyclin D1 expression is a major target of the cAMP-induced inhibition of cell cycle entry in flbroblasts
    • L'ALLEMAIN G, LAVOIE JN, RIVARD N, BALDIN V, POUYSSEGUR J, 1997. Cyclin D1 expression is a major target of the cAMP-induced inhibition of cell cycle entry in flbroblasts. Oncogene 14: 1981-1990.
    • (1997) Oncogene , vol.14 , pp. 1981-1990
    • L'Allemain, G.1    Lavoie, J.N.2    Rivard, N.3    Baldin, V.4    Pouyssegur, J.5
  • 24
    • 0029161583 scopus 로고
    • Inhibition of cyclic nucleotide phosphodiesterase isozymes type-III and type-IV suppress mitogenesis of rat mesangial cells
    • MATOUSOVICK, GRANDE JP, CHINI CCS, CHINI EN, DOUSA TP, 1995. Inhibition of cyclic nucleotide phosphodiesterase isozymes type-III and type-IV suppress mitogenesis of rat mesangial cells. J Clin Invest 96: 401-410.
    • (1995) J Clin Invest , vol.96 , pp. 401-410
    • Matousovic, K.1    Grande, J.P.2    Chini, C.C.S.3    Chini, E.N.4    Dousa, T.P.5
  • 25
    • 0029976573 scopus 로고    scopus 로고
    • cAMP-mediated growth inhibition in flbroblasts is not mediated via mitogen-activated protein (MAP) kinase (ERK) inhibition
    • MCKENZIE FR, POUYSSEGUR J, 1996. cAMP-mediated growth inhibition in flbroblasts is not mediated via mitogen-activated protein (MAP) kinase (ERK) inhibition. J Biol Chem 271: 13476-13483.
    • (1996) J Biol Chem , vol.271 , pp. 13476-13483
    • McKenzie, F.R.1    Pouyssegur, J.2
  • 26
    • 0026450848 scopus 로고
    • Expression of transforming growth factor-β1 is increased in human vascular restenosis lesions
    • NIKOL S, ISNER JM, PICKERING JG, KEARNEY M, LECLERC G, WEIR L, 1992. Expression of transforming growth factor-β1 is increased in human vascular restenosis lesions. J Clin Invest 90: 1582-1592.
    • (1992) J Clin Invest , vol.90 , pp. 1582-1592
    • Nikol, S.1    Isner, J.M.2    Pickering, J.G.3    Kearney, M.4    Leclerc, G.5    Weir, L.6
  • 27
    • 0027190890 scopus 로고
    • Collagen synthesis of human arterial smooth muscle cells: Effects of platelet-derived growth factor, transforming growth factor-β1 and interleukin-1
    • OKADA Y, KATSUDA S, WATANABE H, NAKANISHI I, 1993. Collagen synthesis of human arterial smooth muscle cells: effects of platelet-derived growth factor, transforming growth factor-β1 and interleukin-1. Acta Pathologica Japonica 43: 160-167.
    • (1993) Acta Pathologica Japonica , vol.43 , pp. 160-167
    • Okada, Y.1    Katsuda, S.2    Watanabe, H.3    Nakanishi, I.4
  • 28
    • 0028070508 scopus 로고
    • Synergistic interactions between selective pharmacological inhibitors of phosphodiesterase isozyme families PDE III and PDE IV to attenuate proliferation of rat vascular smooth muscle cells
    • PAN X, ARSUZ E, KRZANOWSKI JJ, FITZPATRICK DF, POLSON JB, 1994. Synergistic interactions between selective pharmacological inhibitors of phosphodiesterase isozyme families PDE III and PDE IV to attenuate proliferation of rat vascular smooth muscle cells. Biochem Pharmacol 48: 827-835.
    • (1994) Biochem Pharmacol , vol.48 , pp. 827-835
    • Pan, X.1    Arsuz, E.2    Krzanowski, J.J.3    Fitzpatrick, D.F.4    Polson, J.B.5
  • 29
    • 0028104858 scopus 로고
    • In vitro effect of platelet-derived growth factor on fibro-proliferation and effect of cytokine antagonists
    • PETERSON TC, ISBRUCKER RA, HOOPER ML, 1994. In vitro effect of platelet-derived growth factor on fibro-proliferation and effect of cytokine antagonists. Immunopharmacol 28: 259-270.
    • (1994) Immunopharmacol , vol.28 , pp. 259-270
    • Peterson, T.C.1    Isbrucker, R.A.2    Hooper, M.L.3
  • 30
    • 0020623702 scopus 로고
    • Role of arterial smooth muscle cell in the pathogenesis of atherosclerosis
    • PIETILA K, NIKKARI T, 1983. Role of arterial smooth muscle cell in the pathogenesis of atherosclerosis. Med Biol 61: 31-44.
    • (1983) Med Biol , vol.61 , pp. 31-44
    • Pietila, K.1    Nikkari, T.2
  • 31
    • 0029958518 scopus 로고    scopus 로고
    • Inhibition by pentoxifylline of extracellular signal-regulated kinase activation by platelet-derived growth factor in hepatic stellate cells
    • PINZANI M, MARRA F, CALIGIURI A, DEFRANCO R, GENTILINI A, FAILLI P, GENTILINI P, 1996. Inhibition by pentoxifylline of extracellular signal-regulated kinase activation by platelet-derived growth factor in hepatic stellate cells. Br J Pharmacol 199: 1117-1114.
    • (1996) Br J Pharmacol , vol.199 , pp. 1117-11114
    • Pinzani, M.1    Marra, F.2    Caligiuri, A.3    DeFranco, R.4    Gentilini, A.5    Failli, P.6    Gentilini, P.7
  • 32
    • 0030795195 scopus 로고    scopus 로고
    • Pentoxifylline inhibits growth and collagen synthesis of cultured human hepatic myofibroblast-like cells
    • PREAUX A-M, MALLAT A, ROSENBAUM J, ZAFRANI E-S, MAVIER P, 1997. Pentoxifylline inhibits growth and collagen synthesis of cultured human hepatic myofibroblast-like cells. Hepatology 26: 315-322.
    • (1997) Hepatology , vol.26 , pp. 315-322
    • Preaux, A.-M.1    Mallat, A.2    Rosenbaum, J.3    Zafrani, E.-S.4    Mavier, P.5
  • 33
    • 0027378273 scopus 로고
    • Regulation of the α1(I) collagen promoter via transforming growth factor-beta activation element
    • RITZENTHALER JD, GOLDSTEIN RH, FINE A, SMITH BD, 1993. Regulation of the α1(I) collagen promoter via transforming growth factor-beta activation element. J Biol Chem 268: 13625-13631.
    • (1993) J Biol Chem , vol.268 , pp. 13625-13631
    • Ritzenthaler, J.D.1    Goldstein, R.H.2    Fine, A.3    Smith, B.D.4
  • 34
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • ROSS R, 1993. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362: 801-809.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 36
    • 0030017253 scopus 로고    scopus 로고
    • Suppression of mesangial proliferative glomerulonephritis development in rats by inhibitors of cAMP phosphodiesterase isozymes types III and IV
    • TSUBOI Y, SHANKLAND SJ, GRANDE JP, WALKER HJ, JOHNSON RJ, DOUSA TP, 1996. Suppression of mesangial proliferative glomerulonephritis development in rats by inhibitors of cAMP phosphodiesterase isozymes types III and IV. J Clin Invest 98: 262-270.
    • (1996) J Clin Invest , vol.98 , pp. 262-270
    • Tsuboi, Y.1    Shankland, S.J.2    Grande, J.P.3    Walker, H.J.4    Johnson, R.J.5    Dousa, T.P.6
  • 37
    • 0023189396 scopus 로고
    • Pentoxifylline, a review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy
    • WARD A, CLISSOLD SP, 1987. Pentoxifylline, a review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy. Drugs 34: 50-97.
    • (1987) Drugs , vol.34 , pp. 50-97
    • Ward, A.1    Clissold, S.P.2
  • 38
    • 0028230233 scopus 로고
    • Antibodies against transforming growth factor-β1 suppress intimal hyperplasia in a rat model
    • WOLF YG, RASMUSSEN LM, RUOSLAHTI, 1994. Antibodies against transforming growth factor-β1 suppress intimal hyperplasia in a rat model. J Clin Invest 93: 1172-1178.
    • (1994) J Clin Invest , vol.93 , pp. 1172-1178
    • Wolf, Y.G.1    Rasmussen, L.M.2    Ruoslahti3
  • 39
    • 0029040836 scopus 로고
    • Pentoxifylline augments but does not antagonize TNFα-mediated neuroblastoma cell differentiation: Modulation of calcium mobilization but not cAMP
    • YANG KD, CHUEN H-L, SHAIO M-F, 1995. Pentoxifylline augments but does not antagonize TNFα-mediated neuroblastoma cell differentiation: modulation of calcium mobilization but not cAMP. Biochem Biophys Res Commun 211: 1006-1014.
    • (1995) Biochem Biophys Res Commun , vol.211 , pp. 1006-1014
    • Yang, K.D.1    Chuen, H.-L.2    Shaio, M.-F.3
  • 40
    • 0030816658 scopus 로고    scopus 로고
    • Migration of medial smooth muscle cells to the intima after balloon injury
    • YOSHIDA Y, MITSUMATA M, LING G, JIANG J, SHU Q, 1997. Migration of medial smooth muscle cells to the intima after balloon injury. Ann NY Acad Sci 811: 459-470.
    • (1997) Ann NY Acad Sci , vol.811 , pp. 459-470
    • Yoshida, Y.1    Mitsumata, M.2    Ling, G.3    Jiang, J.4    Shu, Q.5


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