-
3
-
-
77950462684
-
New insights into the renoprotective actions of the renin inhibitor aliskiren in experimental renal disease
-
Feldman DL. New insights into the renoprotective actions of the renin inhibitor aliskiren in experimental renal disease. Hypertens Res 2010; 33: 279-287.
-
(2010)
Hypertens Res
, vol.33
, pp. 279-287
-
-
Feldman, D.L.1
-
4
-
-
77955415650
-
Application of direct renin inhibition to chronic kidney disease
-
Mende CW. Application of direct renin inhibition to chronic kidney disease. Cardiovasc Drugs Ther 2010; 24: 139-149.
-
(2010)
Cardiovasc Drugs Ther
, vol.24
, pp. 139-149
-
-
Mende, C.W.1
-
5
-
-
84857943830
-
Aliskiren reduced renal fibrosis in mice with chronic ischemic kidney injuy-beyond the direct renin inhibition
-
Sun C-Y, Cherng W-J, Jian H-Z, Hsu H-H, Wu I-W, Hsu H-J, Wu M-S. Aliskiren reduced renal fibrosis in mice with chronic ischemic kidney injuy-beyond the direct renin inhibition. Hypertens Res 2012; 35: 304-311.
-
(2012)
Hypertens Res
, vol.35
, pp. 304-311
-
-
Sun, C.-Y.1
Cherng, W.-J.2
Jian, H.-Z.3
Hsu, H.-H.4
Wu, I.-W.5
Hsu, H.-J.6
Wu, M.-S.7
-
6
-
-
79960175616
-
Aliskiren ameliorates renal inflammation and fibrosis induced by unilateral ureteral obstruction in mice
-
Choi DE, Jeong JY, Lim BJ, Chang YK, Na KR, Shin YT, Lee KW. Aliskiren ameliorates renal inflammation and fibrosis induced by unilateral ureteral obstruction in mice. J Urol 2011; 186: 694-701.
-
(2011)
J Urol
, vol.186
, pp. 694-701
-
-
Choi, D.E.1
Jeong, J.Y.2
Lim, B.J.3
Chang, Y.K.4
Na, K.R.5
Shin, Y.T.6
Lee, K.W.7
-
7
-
-
79951677184
-
Renal protective effects of aliskiren beyond its antihypertensive property in a mouse model of progressive fibrosis
-
Gross O, Girgert R, Rubel D, Temme J, Theissen S, Muller GA. Renal protective effects of aliskiren beyond its antihypertensive property in a mouse model of progressive fibrosis. Am J Hypertens 2011; 24: 355-361.
-
(2011)
Am J Hypertens
, vol.24
, pp. 355-361
-
-
Gross, O.1
Girgert, R.2
Rubel, D.3
Temme, J.4
Theissen, S.5
Muller, G.A.6
-
8
-
-
70349251477
-
Aliskiren enhances the protective effects of valsartan against cardiovascular and renal injury in endothelial nitric oxide synthase-deficient mice
-
Yamamoto E, Kataoka K, Dong YF, Nakamura T, Fukuda M, Tokutomi Y, Matsuba S, Nako H, Nakagata N, Kaneko T, Ogawa H, Kim-Mitsuyama S. Aliskiren enhances the protective effects of valsartan against cardiovascular and renal injury in endothelial nitric oxide synthase-deficient mice. Hypertension 2009; 54: 633-638.
-
(2009)
Hypertension
, vol.54
, pp. 633-638
-
-
Yamamoto, E.1
Kataoka, K.2
Dong, Y.F.3
Nakamura, T.4
Fukuda, M.5
Tokutomi, Y.6
Matsuba, S.7
Nako, H.8
Nakagata, N.9
Kaneko, T.10
Ogawa, H.11
Kim-Mitsuyama, S.12
-
9
-
-
56749131247
-
Prorenin and the (pro)renin receptor: Binding kinetics, signalling and interaction with aliskiren
-
Batenburg WW, Danser AJ. Prorenin and the (pro)renin receptor: binding kinetics, signalling and interaction with aliskiren. J Renin Angiotensin Aldosterone Syst 2008; 9: 181-184.
-
(2008)
J Renin Angiotensin Aldosterone Syst
, vol.9
, pp. 181-184
-
-
Batenburg, W.W.1
Danser, A.J.2
-
10
-
-
79951713169
-
Cooperative interaction of CTGF and TGF-beta in animal models of fibrotic disease
-
Wang Q, Usinger W, Nichols B, Gray J, Xu L, Seeley TW, Brenner M, Guo G, Zhang W, Oliver N, Lin A, Yeowell D. Cooperative interaction of CTGF and TGF-beta in animal models of fibrotic disease. Fibrogenesis Tissue Repair 2011; 4: 4.
-
(2011)
Fibrogenesis Tissue Repair
, vol.4
, pp. 4
-
-
Wang, Q.1
Usinger, W.2
Nichols, B.3
Gray, J.4
Xu, L.5
Seeley, T.W.6
Brenner, M.7
Guo, G.8
Zhang, W.9
Oliver, N.10
Lin, A.11
Yeowell, D.12
-
11
-
-
0033941893
-
Structure-based drug design: The discovery of novel nonpeptide orally active inhibitors of human renin
-
DOI 10.1016/S1074-5521(00)00134-4
-
Rahuel J, Rasetti V, Maibaum J, Rueger H, Goschke R, Cohen NC, Stutz S, Cumin F, Fuhrer W, Wood JM, Grü tter MG. Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human renin. Chem Biol 2000; 7: 493-504. (Pubitemid 30466984)
-
(2000)
Chemistry and Biology
, vol.7
, Issue.7
, pp. 493-504
-
-
Rahuel, J.1
Rasetti, V.2
Maibaum, J.3
Rueger, H.4
Goschke, R.5
Cohen, N.-C.6
Stutz, S.7
Cumin, F.8
Fuhrer, W.9
Wood, J.10
Grutter, M.G.11
-
12
-
-
77957695178
-
Aliskiren binds to renin and prorenin bound to (pro)renin receptor in vitro
-
Biswas KB, Nabi AH, Arai Y, Nakagawa T, Ebihara A, Ichihara A, Watanabe T, Inagami T, Suzuki F. Aliskiren binds to renin and prorenin bound to (pro)renin receptor in vitro. Hypertens Res 2010; 33: 1053-1059.
-
(2010)
Hypertens Res
, vol.33
, pp. 1053-1059
-
-
Biswas, K.B.1
Nabi, A.H.2
Arai, Y.3
Nakagawa, T.4
Ebihara, A.5
Ichihara, A.6
Watanabe, T.7
Inagami, T.8
Suzuki, F.9
-
13
-
-
46449118638
-
Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats
-
Feldman DL, Jin L, Xuan H, Contrepas A, Zhou Y, Webb RL, Mueller DN, Feldt S, Cumin F, Maniara W, Persohn E, Schuetz H, Jan Danser AH, Nguyen G. Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats. Hypertension 2008; 52: 130-136.
-
(2008)
Hypertension
, vol.52
, pp. 130-136
-
-
Feldman, D.L.1
Jin, L.2
Xuan, H.3
Contrepas, A.4
Zhou, Y.5
Webb, R.L.6
Mueller, D.N.7
Feldt, S.8
Cumin, F.9
Maniara, W.10
Persohn, E.11
Schuetz, H.12
Jan Danser, A.H.13
Nguyen, G.14
-
14
-
-
78149298226
-
Mechanisms of tubulointerstitial fibrosis
-
Zeisberg M, Neilson EG. Mechanisms of tubulointerstitial fibrosis. J Am Soc Nephrol 2010; 21: 1819-1834.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1819-1834
-
-
Zeisberg, M.1
Neilson, E.G.2
-
15
-
-
78349289577
-
A reduction of unilateral ureteral obstructioninduced renal fibrosis by a therapy combining valsartan with aliskiren
-
Wu WP, Chang CH, Chiu YT, Ku CL, Wen MC, Shu KH, Wu MJ. A reduction of unilateral ureteral obstructioninduced renal fibrosis by a therapy combining valsartan with aliskiren. Am J Physiol Renal Physiol 2010; 299: F929-F941.
-
(2010)
Am J Physiol Renal Physiol
, vol.299
-
-
Wu, W.P.1
Chang, C.H.2
Chiu, Y.T.3
Ku, C.L.4
Wen, M.C.5
Shu, K.H.6
Wu, M.J.7
-
16
-
-
34848907212
-
Aliskiren, a novel renin inhibitor, is renoprotective in a model of advanced diabetic nephropathy in rats
-
DOI 10.1007/s00125-007-0795-9
-
Kelly DJ, Zhang Y, Moe G, Naik G, Gilbert RE. Aliskiren, a novel renin inhibitor, is renoprotective in a model of advanced diabetic nephropathy in rats. Diabetologia 2007; 50: 2398-2404. (Pubitemid 47512400)
-
(2007)
Diabetologia
, vol.50
, Issue.11
, pp. 2398-2404
-
-
Kelly, D.J.1
Zhang, Y.2
Moe, G.3
Naik, G.4
Gilbert, R.E.5
-
17
-
-
25444454353
-
Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats
-
DOI 10.1161/01.HYP.0000179573.91016.3f
-
Pilz B, Shagdarsuren E, Wellner M, Fiebeler A, Dechend R, Gratze P, Meiners S, Feldman DL, Webb RL, Garrelds IM, Jan Danser AH, Luft FC, Mü ller DN. Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats. Hypertension 2005; 46: 569-576. (Pubitemid 41376839)
-
(2005)
Hypertension
, vol.46
, Issue.3
, pp. 569-576
-
-
Pilz, B.1
Shagdarsuren, E.2
Wellner, M.3
Fiebeler, A.4
Dechend, R.5
Gratze, P.6
Meiners, S.7
Feldman, D.L.8
Webb, R.L.9
Garrelds, I.M.10
Danser, A.H.J.11
Luft, F.C.12
Muller, D.N.13
|