Pirfenidone improves renal function and fibrosis in the post-obstructed kidney

Kidney International

Volumn 54, Issue 1, 1998, Pages 99-109

  Shimizu, Toshikatsu ^a   Kuroda, Takayuki ^b   Hata, Satoshi ^b   Fukagawa, Masafumi ^b   Margolin, Solomon B ^b   Kurokawa, Kiyoshi ^b  

^a SHIONOGI AND CO LTD   (Japan)

^b NONE

Author keywords

Anti fibrotic therapy; Extracellular matrix accumulation; Obstructive nephropathy; TGF ; Tubulointerstitial disease; Unilateral ureteral obstruction

Indexed keywords

GELATINASE A; HYDROXYPROLINE; INULIN; MESSENGER RNA; PIRFENIDONE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; EXPERIMENTAL SURGERY; EXTRACELLULAR MATRIX; GLOMERULUS FILTRATION RATE; HISTOLOGY; KIDNEY FIBROSIS; KIDNEY FUNCTION; MALE; NONHUMAN; NORTHERN BLOTTING; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; URETER OBSTRUCTION;

EID: 0031834709     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1998.00962.x     Document Type: Article

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