TIMP-1 deficiency does not attenuate interstitial fibrosis in obstructive nephropathy

Journal of the American Society of Nephrology

Volumn 12, Issue 4, 2001, Pages 736-748

  Kim, H ^a   Oda, T ^a   Lopez Guisa J ^a   Wing, D ^a   Edwards, D R ^a   Soloway, P D ^a   Eddy, A A ^a  

^a SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 3; GELATINASE B; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROCOLLAGEN; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME DEFICIENCY; GENE INDUCTION; IMMUNOHISTOCHEMISTRY; KIDNEY FIBROSIS; KIDNEY MASS; MACROPHAGE; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; URETER OBSTRUCTION; WESTERN BLOTTING; ZYMOGRAPHY;

EID: 0035086732     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis
2. Experimental diffuse interstitial renal fibrosis. A biochemical approach
3. Matrix metalloproteinases (MMPs) in renal fibrosis
4. Molecular insights into renal interstitial fibrosis
5. Matrix metalloproteinases: A review
6. Experimental insights into the mechanisms of tubulointerstitial scarring
7. Extracellular matrix accumulation in immune-mediated tubulointerstitial injury
8. Altered kidney matrix gene expression in early stages of experimental diabetes
9. Interstitial inflammation and fibrosis in rats with diet-induced hypercholesterolemia
10. Gene expression of metalloproteinases and their inhibitor in renal tissue of New Zealand black/white F1 mice
11. Delayed treatment with enalapril halts tubulointerstitial fibrosis in rats with obstructive nephropathy
12. Altered expression of matrix metalloproteinase-2, TIMP, and TIMP-2 in obstructive nephropathy
13. Differential mRNA expression of renal cortical tissue inhibitor of metalloproteinase-1, -2, and -3 in experimental hydronephrosis
14. Tubular gelatinase A (MMP-2) and its tissue inhibitors in polycystic kidney disease in the Han: SPRD rat
15. Renal extracellular matrix accumulation in acute puromycin amino-nucleoside nephrosis in rats
16. Tissue inhibitors of metalloproteinases: Structure, regulation and biological functions
17. Interstitial fibrosis in mice with overload proteinuria: Deficiency of TIMP-1 is not protective
18. Transcription factor NF-κB regulation of renal fibrosis during ureteral obstruction
19. The role of macrophages and reactive oxygen species in experimental hydronephrosis
20. Targeted mutagenesis of Timp-1 reveals that lung tumor invasion is influenced by Timp-1 genotype of the tumor but not by that of the host
21. Assignment of the TIMP gene to the murine X-chromosome using an inter-species cross
22. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
23. Molecular cloning and expression of the mouse 105-kDa gelatinase cDNA
24. H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen
25. Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity
26. Differential regulation of TIMP-1 and TIMP-2 mRNA expression in normal and Ha-ras-transformed murine fibroblasts
27. Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues
28. Murine tissue inhibitor of metalloproteinases-4 (Timp-4): cDNA isolation and expression in adult mouse tissues
29. Cellular distribution of transforming growth factor-beta 1 and procollagen types I, III, and IV transcripts in carbon tetrachloride-induced rat liver fibrosis
30. Three different fibronectin mRNAs arise by alternative splicing within the coding region
31. cDNA cloning by PCR of rat transforming growth factor beta-1
32. Cloning and sequencing of cDNA for the rat plasminogen activator inhibitor-1
33. Heparin inhibits the induction of three matrix metalloproteinases (stromelysin, 92-kD gelatinase, and collagenase) in primate arterial smooth muscle cells
34. Matrix vesicles are enriched in metalloproteinases that degrade proteoglycans
35. Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates
36. Human stromelysins 1 and 2
37. Differential effects of transforming growth factor-beta 1 on the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in young and old human fibroblasts
38. Acute tubulointerstitial nephritis associated with aminonucleoside nephrosis
39. Role of Fas (CD95) in tubulointerstitial disease induced by unilateral ureteric obstruction
40. Protein restriction reduces transforming growth factor-beta and interstitial fibrosis in nephrotic syndrome
41. Modifications of a specific assay for hydroxyproline in urine
42. Immunohisto-chemical study of metalloproteinases and their tissue inhibitors in the lungs of patients with diffuse alveolar damage and idiopathic pulmonary fibrosis
43. Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors
44. Mechanisms for pro matrix metalloproteinase activation
45. Matrix metalloproteinase degradation of extracellular matrix: Biological consequences
46. Matrix metalloproteinases: Implication in vascular matrix remodelling during atherogenesis
47. Gelatinase B/lacZ transgenic mice, a model for mapping gelatinase B expression during developmental and injury-related tissue remodeling
48. In vitro suppression of programmed cell death of B cells by tissue inhibitor of metalloproteinases-1
49. Expression of tissue inhibitor of matrix metalloproteinases 1 by use of an adenoviral vector inhibits smooth muscle cell migration and reduces neointimal hyperplasia in the rat model of vascular balloon injury
50. Expression of genes that promote renal interstitial fibrosis in rats with proteinuria