Unravelling mitochondrial pathways to Parkinson's disease

British Journal of Pharmacology

Volumn 171, Issue 8, 2014, Pages 1943-1957

  Celardo, I ^a   Martins, L M ^a   Gandhi, S ^b  

^a MRC TOXICOLOGY UNIT   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

calcium; free radicals; mitochondria; mitophagy; oxidative stress; PARKIN; Parkinson's disease; PINK1; respiratory chain

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ADENOSINE TRIPHOSPHATE; ALPHA SYNUCLEIN; ALPHA TOCOPHEROL; DJ 1 PROTEIN; INTERLEUKIN 1BETA; METFORMIN; MITOCHONDRIAL DNA; PARKIN; PROTEIN KINASE; PTEN INDUCED PUTATIVE KINASE; RAPAMYCIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; TOLL LIKE RECEPTOR 9; UBIDECARENONE; UNCLASSIFIED DRUG; CALCIUM;

AUTOPHAGY; BASE MISPAIRING; ENDOPLASMIC RETICULUM STRESS; HUMAN; LIPID PEROXIDATION; LOSS OF FUNCTION MUTATION; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL GENOME; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MITOPHAGY; MPTP-INDUCED PARKINSONISM; NERVE DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; REVIEW; UNFOLDED PROTEIN RESPONSE; ANIMAL; BIOLOGICAL MODEL; COMPLICATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GENETICS; HOMEOSTASIS; INFLAMMATION; METABOLISM; MITOCHONDRIAL DYNAMICS; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; CALCIUM; DNA, MITOCHONDRIAL; HOMEOSTASIS; HUMANS; INFLAMMATION; MITOCHONDRIAL DEGRADATION; MITOCHONDRIAL DISEASES; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL TURNOVER; MODELS, BIOLOGICAL; NERVE DEGENERATION; NEURONS; PARKINSON DISEASE;

EID: 84896727104     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12433     Document Type: Review

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