Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance

Journal of Cell Science

Volumn 124, Issue 7, 2011, Pages 1115-1125

  Heeman, Bavo ^a   Van den Haute, Chris ^a   Aelvoet, Sarah Ann ^a   Valsecchi, Federica ^b,c   Rodenburg, Richard J ^c   Reumers, Veerle ^a   Debyser, Zeger ^a   Callewaert, Geert ^a   Koopman, Werner J H ^b   Willems, Peter H G M ^b   Baekelandt, Veerle ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Lentiviral vector; Live cell imaging; Mitochondria; Parkinson's disease

Indexed keywords

ADENOSINE TRIPHOSPHATE; MITOCHONDRIAL PROTEIN; PROTEIN PINK1; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOLUMINESCENCE; CALCIUM HOMEOSTASIS; ENERGY; GENE SILENCING; GENETIC DISORDER; IN VIVO STUDY; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; FEMALE; GENE KNOCKDOWN TECHNIQUES; HOMEOSTASIS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; PARKINSON DISEASE; PROTEIN KINASES; REACTIVE OXYGEN SPECIES;

MUS;

EID: 79953156438     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.078303     Document Type: Article

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