Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex I with rotenone

Journal of Neuroscience

Volumn 27, Issue 27, 2007, Pages 7310-7317

  Yadava, Nagendra ^a   Nicholls, David G ^a  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

Author keywords

Complex I; Excitotoxicity; Membrane potential; Mitochondria; Rotenone; Superoxide

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; OLIGOMYCIN; OXYGEN; PORPHYRIN DERIVATIVE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; SUPEROXIDE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BIOENERGY; BREATHING; CELL CULTURE; CELL DEATH; CELL RESPIRATION; CEREBELLUM; CYTOPLASM; DRUG INHIBITION; ENZYME INHIBITION; EXCITOTOXICITY; GRANULE CELL; MITOCHONDRION; MONITORING; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RESPIRATORY FAILURE; STIMULATION;

ANIMALS; CELL DEATH; CELL RESPIRATION; ELECTRON TRANSPORT COMPLEX I; EXCITATORY AMINO ACID AGONISTS; GLUTAMIC ACID; MITOCHONDRIA; OXIDATIVE STRESS; RATS; RATS, WISTAR; ROTENONE;

EID: 34447122557     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0212-07.2007     Document Type: Article

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