Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response

Cell Death and Differentiation

Volumn 16, Issue 3, 2009, Pages 449-464

  Moisoi, N ^a   Klupsch, K ^b   Fedele, V ^a   East, P ^b   Sharma, S ^c   Renton, A ^c   Plun Favreau, H ^c   Edwards, R E ^a   Teismann, P ^d   Esposti, M D ^e   Morrison, A D ^f   Wood, N W ^c   Downward, J ^b   Martins, L M ^a  

^a MRC TOXICOLOGY UNIT   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^d UNIVERSITY OF ABERDEEN   (United Kingdom)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

^f GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; REACTIVE OXYGEN METABOLITE; SERINE PROTEINASE OMI;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; BRAIN TISSUE; CELL STRESS; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EMBRYO; MITOCHONDRIAL RESPIRATION; MOUSE; NERVE CELL NECROSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FOLDING; TRANSCRIPTION REGULATION; UNINDEXED SEQUENCE; UPREGULATION;

ANIMALS; ANTIOXIDANTS; BRAIN; CELL RESPIRATION; CORPUS STRIATUM; HUMANS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; NEURONS; OXIDATIVE STRESS; PARKINSON DISEASE; REACTIVE OXYGEN SPECIES; SERINE ENDOPEPTIDASES; TISSUE DISTRIBUTION; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION, GENETIC;

MUS; PARKINSONIA;

EID: 60849097548     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2008.166     Document Type: Article

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