Ambiguities in NLRP3 inflammasome regulation: Is there a role for mitochondria?

Biochimica et Biophysica Acta - General Subjects

Volumn 1840, Issue 4, 2014, Pages 1433-1440

  Lawlor, Kate E ^a,b   Vince, James E ^a,b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Caspase 1; IL 1 ; Inflammasome; Mitochondria; NLRP3; Reactive oxygen species

Indexed keywords

CRYOPYRIN; INFLAMMASOME; INHIBITOR OF APOPTOSIS PROTEIN 1; INHIBITOR OF APOPTOSIS PROTEIN 2; MITOCHONDRIAL DNA; PROTEIN BCL 2; PROTEIN KINASE R; REACTIVE OXYGEN METABOLITE; THIOREDOXIN INTERACTING PROTEIN; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; X LINKED INHIBITOR OF APOPTOSIS;

ALZHEIMER DISEASE; APOPTOSIS; ATHEROSCLEROSIS; AUTOINFLAMMATORY DISEASE; CELLULAR DISTRIBUTION; DISEASE ASSOCIATION; GENE MUTATION; HUMAN; MITOCHONDRION; MITOPHAGY; NEOPLASM; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; REVIEW;

CASPASE-1; IL-1Β; INFLAMMASOME; MITOCHONDRIA; NLRP3; REACTIVE OXYGEN SPECIES;

ANIMALS; APOPTOSIS; CARRIER PROTEINS; HUMANS; INFLAMMASOMES; LYSOSOMES; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES;

EID: 84895524321     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.08.014     Document Type: Review

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