AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages

Cell Death and Differentiation

Volumn 19, Issue 10, 2012, Pages 1709-1721

  Pierini, R ^a,b   Juruj, C ^a,b   Perret, M ^a,b   Jones, C L ^c   Mangeot, P ^a,b   Weiss, D S ^c,d   Henry, T ^a,b  

^a UNIVERSITÉ DE LYON   (France)

^b INSERM   (France)

^c EMORY UNIVERSITY   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AIM2; ASC; bacterial infections; caspase 8; Francisella; inflammasome

Indexed keywords

CASPASE 8; CASPASE 9; GAMMA INTERFERON; INFLAMMASOME; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN AIM2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; ENZYME INHIBITION; FRANCISELLA TULARENSIS; IN VITRO STUDY; IN VIVO STUDY; KINETICS; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION;

ANIMALS; APOPTOSIS; CASPASE 1; CASPASE 3; CASPASE 8; CELLS, CULTURED; CYTOKINES; CYTOSKELETAL PROTEINS; FRANCISELLA TULARENSIS; HEK293 CELLS; HUMANS; INFLAMMASOMES; MACROPHAGES; MICE; MICE, KNOCKOUT; NUCLEAR PROTEINS; TULAREMIA;

BACTERIA (MICROORGANISMS); FRANCISELLA; FRANCISELLA TULARENSIS; MUS;

EID: 84866087868     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2012.51     Document Type: Article

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