Proinsulin entry and transit through the endoplasmic reticulum in pancreatic beta cells

Vitamins and Hormones

Volumn 95, Issue , 2014, Pages 35-62

  Liu, Ming ^a,b   Wright, Jordan ^a   Guo, Huan ^a   Xiong, Yi ^a   Arvan, Peter ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Diabetes; Endoplasmic reticulum; Pancreatic beta cells; Preproinsulin; Proinsulin; Protein folding; Protein translocation

Indexed keywords

INSULIN; PREPROINSULIN; PROINSULIN; PROTEIN PRECURSOR; SIGNAL PEPTIDE;

ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; CHEMISTRY; CYTOLOGY; CYTOSOL; DIABETES MELLITUS; ENDOPLASMIC RETICULUM; HUMAN; METABOLISM; PANCREAS; PANCREAS ISLET BETA CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN DEGRADATION; PROTEIN FOLDING; SECRETION (PROCESS); TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; CYTOSOL; DIABETES MELLITUS; ENDOPLASMIC RETICULUM; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MODELS, BIOLOGICAL; PANCREAS; PROINSULIN; PROTEIN FOLDING; PROTEIN PRECURSORS; PROTEIN SORTING SIGNALS; PROTEOLYSIS;

EID: 84894046601     PISSN: 00836729     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-800174-5.00002-8     Document Type: Chapter

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