Endoplasmic reticulum stress response in an INS-1 pancreatic β-cell line with inducible expression of a folding-deficient proinsulin

BMC Cell Biology

Volumn 11, Issue , 2010, Pages

  Hartley, Taila ^a,b   Siva, Madura ^a,b   Lai, Elida ^a,b   Teodoro, Tracy ^a,b   Zhang, Liling ^a   Volchuk, Allen ^a,b,c  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; APOPTOSIS INDUCING FACTOR; CELL PROTEIN; ENHANCED GREEN FLUORESCENT PROTEIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INSULIN; PROTEIN IRE1; PROTEIN PERK; PROTEIN TRIB3; UNCLASSIFIED DRUG; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; INSULIN I, MOUSE; PROINSULIN; PROTEASOME;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL METABOLISM; CELL SURVIVAL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE INDUCTION; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PROTEIN FOLDING; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL; CELL LINE; ENDOPLASMIC RETICULUM; GENETICS; METABOLISM; MICROARRAY ANALYSIS; MOUSE; MOUSE MUTANT; PATHOLOGY; PROTEIN ENGINEERING; TRANSGENE; UNFOLDED PROTEIN RESPONSE;

ANIMALS; APOPTOSIS; CELL LINE; ENDOPLASMIC RETICULUM; GENE EXPRESSION PROFILING; GREEN FLUORESCENT PROTEINS; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, MUTANT STRAINS; MICROARRAY ANALYSIS; PROINSULIN; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN ENGINEERING; PROTEIN FOLDING; RECOMBINANT FUSION PROTEINS; TRANSGENES; UNFOLDED PROTEIN RESPONSE;

EID: 77954872755     PISSN: None     EISSN: 14712121     Source Type: Journal    
DOI: 10.1186/1471-2121-11-59     Document Type: Article

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