Behavior in the eukaryotic secretory pathway of insulin-containing fusion proteins and single-chain insulins bearing various B-chain mutations

Journal of Biological Chemistry

Volumn 278, Issue 6, 2003, Pages 3687-3693

  Zhang, Bao Yan ^a   Liu, Ming ^a   Arvan, Peter ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; ISOMERS; MOLECULES; OLIGOMERS;

SECRETORY PATHWAYS;

PROTEINS;

DISULFIDE; DITHIOTHREITOL; HYBRID PROTEIN; INSULIN; MUTANT PROTEIN; PROINSULIN; PROTEIN PRECURSOR; THIOL DERIVATIVE;

ARTICLE; BETA CHAIN; CONTROLLED STUDY; DIMERIZATION; DISULFIDE BOND; EUKARYOTE; GENE EXPRESSION; HUMAN; HUMAN CELL; INSULIN RELEASE; INSULIN SYNTHESIS; INTRACELLULAR TRANSPORT; ISOMER; MUTATIONAL ANALYSIS; NONHUMAN; OLIGOMERIZATION; OXIDATION; POINT MUTATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TRANSPORT; YEAST CELL; CELL LINE; CHEMISTRY; METABOLISM; MUTATION; SACCHAROMYCES CEREVISIAE; SECRETION;

EUKARYOTA; MAMMALIA;

CELL LINE; DISULFIDES; DITHIOTHREITOL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; INSULIN; MUTATION; POINT MUTATION; PROTEIN FOLDING; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE;

EID: 0037423397     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209474200     Document Type: Article

References (67)

1. Steiner, D. F., and James, D. E. (1992) Diabetologia 35, (suppl. 2) S41-S48
2. Cheung, A. T., Dayanandan, B., Lewis, J. T., Korbutt, G. S., Rajotte, R. V., Bryer-Ash, M., Boylan, M. O., Wolfe, M. M., and Kieffer, T. J. (2000) Science 290, 1959-1962
3. Kjeldsen, T., Balschmidt, P., Diers, I., Hach, M., Kaarsholm, N. C., and Ludvigsen, S. (2001) Biotechnol. Genet. Eng. Rev. 18, 89-121
4. Hua, Q. X., Hu, S. Q., Jia, W., Chu, Y. C., Burke, G. T., Wang, S. H., Wang, R. Y., Katsoyannis, P. G., and Weiss, M. A. (1998) J. Mol. Biol. 277, 103-118
5. Zhang, B.-y., Chang, A., Kjeldsen, T. B., and Arvan, P. (2001) J. Cell Biol. 153, 1187-1197
6. Frank, B. H., and Veros, A. J. (1968) Biochem. Biophys. Res. Communun. 32, 155-160
7. Grant, P. T., Coombs, T. L., and Frank, B. H. (1972) Biochem. J. 126, 433-440
8. Steiner, D. F. (1973) Nature 243, 528-530
9. Baker, E. N., Blundell, T. L., Cutfield, J. F., Cutfield, S. M., Dodson, E. J., Dodson, G. G., Hodgkin, D. M. C., Hubbard, R. E., Isaacs, N. W., Reynolds, C. D., Sakabe, K., Sakabe, N., and Vijayan, N. M. (1988) Philos. Trans. R. Soc. Lond.-Biol. Sci. 319, 369-456
10. Kuliawat, R., and Arvan, P. (1994) J. Cell Biol. 126, 77-86
11. Huang, X. F., and Arvan, P. (1995) J. Biol. Chem. 270, 20417-20423
12. Arvan, P., Zhang, B.-y., Feng, L., Liu, M., and Kuliawat, R. (2002) Curr. Opin. Cell Biol. 14, 448-453
13. Arvan, P., Zhao, X., Ramos-Castañeda, J., and Chang, A. (2002) Traffic 3, 771-780
14. Dodson, G., and Steiner, D. (1998) Curr. Opin. Struct. Biol. 8, 189-194
15. Chen, H., Shi, M., Guo, Z. Y., Tang, Y. H., Qiao, Z. S., Liang, Z. H., and Feng, Y. M. (2000) Protein Eng. 13, 779-782
16. Brange, J., Ribel, U., Hansen, G., Dodson, G., Hansen, M. T., Havelund, S., Melberg, S. G., Norris, F., Norris, K., Snel, L., Sorensen, A. R., and Voigt, H. O. (1988) Nature 333, 679-682
17. Jorgensen, A. M., Kristensen, S. M., Led, J. J., and Balschmidt, P. (1992) J. Mol. Biol. 227, 1146-1163
18. Ciszak, E., Beals, J. M., Frank, B. H., Baker, J. C., Carter, N. D., and Smith, G. D. (1995) Structure 3, 615-622
19. Carroll, R. J., Hammer, R. E., Chan, S. J., Swift, H. H., Rubenstein, A. H., and Steiner, D. F. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 8943-8947
20. Kaarsholm, N. C., Ko, H. C., and Dunn, M. F. (1989) Biochemistry 28, 4427-4435
21. Marcusson, E. G., Horazdovsky, B. F., Cereghino, J. L., Gharakhanian, E., and Emr, S. D. (1994) Cell 77, 579-586
22. Sikorski, R. S., and Hieter, P. (1989) Genetics 122, 19-27
23. Nothwehr, S. F., Ha, S. A., and Bruinsma, P. (2000) J. Cell Biol. 151, 297-310
24. Schagger, H., and von Jagow, G. (1987) Anal. Biochem. 166, 368-379
25. Yao, Z. P., Zeng, Z. H., Li, H. M., Zhang, Y., Feng, Y. M., and Wang, D. C. (1999) Acta Crystallogr. Sect. D Biol. Crystallogr. 55, 1524-1532
26. Zhang, Y., Whittingham, J. L., Turkenburg, J. P., Dodson, E. J., Brange, J., and Dodson, G. G. (2002) Acta Crystallogr. Sect. D Biol. Crystallogr. 58, 186-187
27. Hua, Q. X., Nakagawa, S. H., Jia, W., Hu, S. Q., Chu, Y. C., Katsoyannis, P. G., and Weiss, M. A. (2001) Biochemistry 40, 12299-12311
28. Guo, Z. Y., Shen, L., and Feng, Y. M. (2002) Biochemistry 41, 10585-10592
29. Hong, E., Davidson, A. R., and Kaiser, C. A. (1996) J. Cell Biol. 135, 623-633
30. Holkeri, H., and Makarow, M. (1998) FEBS Lett. 429, 162-166
31. Jorgensen, M. U., Emr, S. D., and Winther, J. R. (1999) Eur. J. Biochem. 260, 461-469
32. Yuan, Y., Wang, Z. H., and Tang, J. G. (1999) Biochem. J. 343, 139-144
33. Qiao, Z. S., Guo, Z. Y., and Feng, Y. M. (2001) Biochem. 40, 2662-2668
34. Frand, A. R., and Kaiser, C. A. (1998) Mol. Cell 1, 161-170
35. Sieber, P., Eisler, K., Kamber, B., Riniker, B., Rittel, W., Marki, F., and de Gasparo, M. (1978) Hoppe-Seyler's Z. Physiol. Chem. 359, 113-123
36. Elliott, S., Fagin, K. D., Narhi, L. O., Miller, J. A., Jones, M., Koski, R., Peters, M., Hsieh, P., Sachdev, R., and Rosenfeld, R. D. (1990) J. Protein Chem. 9, 95-104
37. Steube, K., Chaudhuri, B., Marki, W., Merryweather, J. P., and Heim, J. (1991) Eur. J. Biochem. 198, 651-657
38. Hua, Q. X., Gozani, S. N., Chance, R. E., Hoffmann, J. A., Frank, B. H., and Weiss, M. A. (1995) Nat. Struct. Biol. 2, 129-138
39. Freedman, R. B., Klappa, P., and Ruddock, L. W. (2002) EMBO Rep. 3, 136-140
40. Ellgaard, L., and Helenius, A. (2001) Curr. Opin. Cell Biol. 13, 431-437
41. Gruppuso, P. A., Gorden, P., Kahn, C. R., Cornblath, M., Zeller, W. P., and Schwartz, R. (1984) N. Engl. J. Med. 311, 629-634
42. Chan, S. J., Seino, S., Gruppuso, P. A., Schwartz, R., and Steiner, D. F. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 2194-2197
43. Quinn, D., Orci, L., Ravazzola, M., and Moore, H.-P. H. (1991) J. Cell Biol. 113, 987-996
44. Arvan, P., Kuliawat, R., Prabakaran, D., Zavacki, A. M., Elahi, D., Wang, S., and Pilkey, D. (1991) J. Biol. Chem. 266, 14171-14174
45. Kuliawat, R., and Arvan, P. (1992) J. Cell Biol. 118, 521-529
46. Kuliawat, R., Prabakaran, D., and Arvan, P. (2000) Mol. Biol. Cell 11, 1959-1972
47. Kjeldsen, T. (2000) Appl. Microbiol. Biotechnol. 54, 277-286, 2000
48. Weiss, M. A., Hua, Q. X., Jia, W., Nakagawa, S. H., Chu, Y. C., Hu, S. Q., and Katsoyannis, P. G. (2001) J. Biol. Chem. 276, 40018-40024
49. Weiss, M. A., Wan, Z., Zhao, M., Chu, Y. C., Nakagawa, S. H., Burke, G. T., Jia, W., Hellmich, R., and Katsoyannis, P. G. (2002) J. Mol. Biol. 315, 103-111
50. Hurtley, S. M., and Helenius, A. (1989) Annu. Rev. Cell Biol. 5, 277-307
51. Kowarik, M., Küng, S., Martoglio, B., and Helenius, A. (2002) Mol. Cell 10, 769-778
52. Scheele, G., and Jacoby, R. (1983) J. Biol. Chem. 258, 2005-2009
53. Anelli, T., Alessio, M., Mezghrani, A., Simmen, T., Talamo, F., Bachi, A., and Sitia, R. (2002) EMBO J 21, 835-844
54. Rowling, P. J. E., and Freedman, R. B. (1993) in Subcellular Biochemistry (Borgese, N., and Harris, J. R., eds) Vol. 21, pp. 41-80, Plenum Press, New York
55. Hober, S., Forsberg, G., Palm, G., Hartmanis, M., and Nilsson, B. (1992) Biochemistry 31, 1749-1756
56. Smith, M. C., Cook, J. A., Furman, T. C., and Occolowitz, J. L. (1989) J. Biol. Chem. 264, 9314-9321
57. Narhi, L. O., Hua, Q. X., Arakawa, T., Fox, G. M., Tsai, L., Rosenfeld, R., Holst, P., Miller, J. A., and Weiss, M. A. (1993) Biochem. 32, 5214-5221
58. Hober, S., Lundstrom Ljung, J., Uhlen, M., and Nilsson, B. (1999) FEBS Lett. 443, 271-276
59. Miller, J. A., Narhi, L. O., Hua, Q. X., Rosenfeld, R., Arakawa, T., Rohde, M., Prestrelski, S., Lauren, S., Stoney, K. S., Tsai, L., and Weiss, M. A. (1993) Biochemistry 32, 5203-5213
60. Milner, S. J., Carver, J. A., Ballard, F. J., and Francis, G. L. (1999) Biotechnol. Bioeng. 62, 693-703
61. Rosenfeld, R. D., Noone, N. M., Lauren, S. L., Rohde, M. F., Narhi, L. O., and Arakawa, T. (1993) J. Protein Chem. 12, 247-254
62. Guo, Z. Y., Shen, L., and Feng, Y. M. (2002) Biochemistry 41, 1556-1567
63. Bullesbach, E. E., and Schwabe, C. (2001) J. Pept. Res. 57, 77-83
64. Lee, H. C., Kim, S. J., Kim, K. S., Shin, H. C., and Yoon, J. W. (2000) Nature 408, 483-488
65. Tang, J. G., Wang, C. C., and Tsou, C. L. (1988) Biochem. J. 255, 451-455
66. Joly, J. C., and Swartz, J. R. (1994) Biochemistry 33, 4231-4236
67. Winter, J., Klappa, P., Freedman, R. B., Lilie, H., and Rudolph, R. (2002) J. Biol. Chem. 277, 310-317