Standard role for a conserved aspartate or more direct involvement in deglycosylation? an ONIOM and MD investigation of adenine-DNA glycosylase

Biochemistry

Volumn 52, Issue 48, 2013, Pages 8753-8765

  Kellie, Jennifer L ^a   Wilson, Katie A ^a   Wetmore, Stacey D ^a  

^a UNIVERSITY OF LETHBRIDGE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC FUNCTIONS; COMPUTATIONAL STUDIES; CONFORMATIONAL DYNAMICS; GEOBACILLUS STEAROTHERMOPHILUS; GLYCOSIDIC BOND; NUCLEOPHILIC ATTACK; QUANTUM MECHANICAL; REACTION POTENTIAL;

CATALYSIS; MOLECULAR DYNAMICS; PROTONATION; QUANTUM CHEMISTRY; QUANTUM THEORY; REACTION KINETICS; REPAIR;

DNA;

8 HYDROXYGUANINE; ADENINE; ASPARTIC ACID; DNA GLYCOSYLASE MUTY; DNA GLYCOSYLTRANSFERASE; NUCLEIC ACID BASE;

ARTICLE; CATALYSIS; CONFORMATION; CRYSTAL STRUCTURE; DEGLYCOSYLATION; DNA DAMAGE; ENZYME ACTIVE SITE; GEOBACILLUS STEAROTHERMOPHILUS; HYDROGEN BOND; HYDROLYSIS; MOLECULAR DYNAMICS; NONHUMAN; NUCLEOPHILICITY; PRIORITY JOURNAL; PROTON TRANSPORT; QUANTUM MECHANICS; RECOGNITION;

EID: 84889241044     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi401310w     Document Type: Article

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