Role of environment for catalysis of the DNA repair enzyme MutY

Journal of the American Chemical Society

Volumn 134, Issue 20, 2012, Pages 8608-8616

  Brunk, Elizabeth ^a   Arey, J Samuel ^a,b   Rothlisberger, Ursula ^a  

^a EPFL   (Switzerland)

^b SWISS FEDERAL INSTITUTE OF AQUATIC SCIENCE AND TECHNOLOGY   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; CATALYTIC RESIDUE; CLASSICAL MOLECULAR DYNAMICS; DNA-REPAIR ENZYMES; ENVIRONMENT EFFECTS; HYDROGEN BONDING NETWORK; HYDROPHILIC RESIDUES; HYDROPHOBIC RESIDUES; MICROENVIRONMENTS; RESIDENCE TIME; SOLVATION PATTERNS; SOLVENT MOLECULES; WATER MOLECULE; WATER TRAPS;

CATALYSIS; ENZYMES; HYDROGEN; HYDROPHILICITY; HYDROPHOBICITY; MOLECULAR DYNAMICS; PROTONATION; REACTION INTERMEDIATES; REACTION KINETICS; SOLVENTS;

MOLECULES;

ADENINE; CELL ENZYME; MUTY ENZYME; UNCLASSIFIED DRUG; WATER;

ARTICLE; CATALYSIS; CHEMICAL REACTION; DNA REPAIR; ENTHALPY; ENTROPY; ENVIRONMENTAL FACTOR; HYDROGEN BOND; HYDROPHILICITY; HYDROPHOBICITY; MICROENVIRONMENT; NONHUMAN; PROTON TRANSPORT; STRUCTURE ANALYSIS;

CATALYSIS; CATALYTIC DOMAIN; DNA GLYCOSYLASES; DNA REPAIR; ESCHERICHIA COLI; GEOBACILLUS STEAROTHERMOPHILUS; MODELS, MOLECULAR; WATER;

EID: 84861398910     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja301714j     Document Type: Article

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