Transition-state analysis of the DNA repair enzyme MutY

Journal of the American Chemical Society

Volumn 130, Issue 17, 2008, Pages 5789-5797

  McCann, Joe A B ^b   Berti, Paul J ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; ENZYME ACTIVITY; HYDROLYSIS; WATER ANALYSIS;

KINETIC ISOTOPE EFFECT (KIE); TRANSITION STATE (TS);

DNA SEQUENCES;

ADENINE; DEUTERIUM; DNA; DNA REPAIR PROTEIN MUTY; GLYCOSIDE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; SOLVENT; SUGAR; WATER;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; DNA SEQUENCE; DNA STRUCTURE; HYDROGEN BOND; HYDROLYSIS; IN VIVO STUDY; ISOTOPE ANALYSIS; MICHAEL ADDITION; PROTEIN DEGRADATION; PROTON TRANSPORT; WATER FLOW;

CARBON; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; DNA; DNA GLYCOSYLASES; DNA REPAIR; GLYCOSIDES; HYDROLYSIS; ISOTOPES; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; NITROGEN; PROTONS; SOLVENTS;

EID: 42649085059     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja711363s     Document Type: Article

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