-
1
-
-
0000049491
-
Experimental transmission of trembling to the goat. Comptes Rendus Séances Acad
-
Cuille, J. & Chelle, P. L. Experimental transmission of trembling to the goat. Comptes Rendus Séances Acad. Sci. 208, 1058-1160 (1939).
-
(1939)
Sci.
, vol.208
, pp. 1058-1160
-
-
Cuille, J.1
Chelle, P.L.2
-
2
-
-
78651041685
-
Degenerative disease of the central nervous system in New Guinea; The endemic occurrence of kuru in the native population
-
Gajdusek, D. C. & Zigas, V. Degenerative disease of the central nervous system in New Guinea; the endemic occurrence of kuru in the native population. N. Engl. J. Med. 257, 974-978 (1957).
-
(1957)
N. Engl. J. Med.
, vol.257
, pp. 974-978
-
-
Gajdusek, D.C.1
Zigas, V.2
-
3
-
-
0016398968
-
Letter: Possible person-to-person transmission of Creutzfeldt-Jakob disease
-
Duffy, P. et al. Letter: possible person-to-person transmission of Creutzfeldt-Jakob disease. N. Engl. J. Med. 290, 692-693 (1974).
-
(1974)
N. Engl. J. Med.
, vol.290
, pp. 692-693
-
-
Duffy, P.1
-
4
-
-
0342951746
-
A new variant of Creutzfeldt-Jakob disease in the UK
-
DOI 10.1016/S0140-6736(96)91412-9
-
Will, R. G. et al. A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 347, 921-925 (1996). (Pubitemid 26102546)
-
(1996)
Lancet
, vol.347
, Issue.9006
, pp. 921-925
-
-
Will, R.G.1
Ironside, J.W.2
Zeidler, M.3
Cousens, S.N.4
Estibeiro, K.5
Alperovitch, A.6
Poser, S.7
Pocchiari, M.8
Hofmar, A.9
Smith, P.G.10
-
5
-
-
1142273431
-
Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion
-
DOI 10.1016/S0140-6736(04)15486-X
-
Llewelyn, C. A. et al. Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion. Lancet 363, 417-421 (2004). (Pubitemid 38210057)
-
(2004)
Lancet
, vol.363
, Issue.9407
, pp. 417-421
-
-
Llewelyn, C.A.1
Hewitt, P.E.2
Knight, R.S.G.3
Amar, K.4
Cousens, S.5
MacKenzie, J.6
Will, R.G.7
-
6
-
-
84876014342
-
Prion infectivity in the spleen of a PRNP heterozygous individual with subclinical variant Creutzfeldt-Jakob disease
-
Bishop, M. T. et al. Prion infectivity in the spleen of a PRNP heterozygous individual with subclinical variant Creutzfeldt-Jakob disease. Brain 136, 1139-1145 (2013).
-
(2013)
Brain
, vol.136
, pp. 1139-1145
-
-
Bishop, M.T.1
-
7
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
Prusiner, S. B. Novel proteinaceous infectious particles cause scrapie. Science 216, 136-144 (1982). (Pubitemid 12089840)
-
(1982)
Science
, vol.216
, Issue.4542
, pp. 136-144
-
-
Prusiner, S.B.1
-
8
-
-
72149118250
-
An analytical solution to the kinetics of breakable filament assembly
-
Knowles, T. P. et al. An analytical solution to the kinetics of breakable filament assembly. Science 326, 1533-1537 (2009).
-
(2009)
Science
, vol.326
, pp. 1533-1537
-
-
Knowles, T.P.1
-
9
-
-
0030054010
-
Normal host prion protein necessary for scrapie-induced neurotoxicity
-
DOI 10.1038/379339a0
-
Brandner, S. et al. Normal host prion protein necessary for scrapie-induced neurotoxicity. Nature 379, 339-343 (1996). (Pubitemid 26033075)
-
(1996)
Nature
, vol.379
, Issue.6563
, pp. 339-343
-
-
Brandner, S.1
Isenmann, S.2
Raeber, A.3
Fischer, M.4
Sailer, A.5
Kobayashi, Y.6
Marino, S.7
Weissmann, C.8
Aguzzi, A.9
-
10
-
-
42049099020
-
Physiology of the prion protein
-
DOI 10.1152/physrev.00007.2007
-
Linden, R. et al. Physiology of the prion protein. Physiol. Rev. 88, 673-728 (2008). (Pubitemid 351520090)
-
(2008)
Physiological Reviews
, vol.88
, Issue.2
, pp. 673-728
-
-
Linden, R.1
Martins, V.R.2
Prado, M.A.M.3
Cammarota, M.4
Izquierdo, I.5
Brentani, R.R.6
-
11
-
-
84872168596
-
Microglia: Scapegoat, saboteur, or something else
-
Aguzzi, A., Barres, B. A. & Bennett, M. L. Microglia: scapegoat, saboteur, or something else Science 339, 156-161 (2013).
-
(2013)
Science
, vol.339
, pp. 156-161
-
-
Aguzzi, A.1
Barres, B.A.2
Bennett, M.L.3
-
12
-
-
4544224048
-
Antiprion immunotherapy: To suppress or to stimulate
-
Aguzzi, A. & Sigurdson, C. J. Antiprion immunotherapy: to suppress or to stimulate Nature Rev. Immunol. 4, 725-736 (2004).
-
(2004)
Nature Rev. Immunol.
, vol.4
, pp. 725-736
-
-
Aguzzi, A.1
Sigurdson, C.J.2
-
13
-
-
0026600865
-
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
-
Bueler, H. et al. Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature 356, 577-582 (1992).
-
(1992)
Nature
, vol.356
, pp. 577-582
-
-
Bueler, H.1
-
14
-
-
77649091387
-
Axonal prion protein is required for peripheral myelin maintenance
-
Bremer, J. et al. Axonal prion protein is required for peripheral myelin maintenance. Nature Neurosci. 13, 310-318 (2010).
-
(2010)
Nature Neurosci.
, vol.13
, pp. 310-318
-
-
Bremer, J.1
-
15
-
-
79953691810
-
Prion protein expression regulates embryonic stem cell pluripotency and differentiation
-
Miranda, A., Pericuesta, E., Ramirez, M. A. & Gutierrez-Adan, A. Prion protein expression regulates embryonic stem cell pluripotency and differentiation. PLoS ONE 6, e18422 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Miranda, A.1
Pericuesta, E.2
Ramirez, M.A.3
Gutierrez-Adan, A.4
-
16
-
-
84862775532
-
Requirement of cellular prion protein for intestinal barrier function and mislocalization in patients with inflammatory bowel disease
-
Petit, C. S. et al. Requirement of cellular prion protein for intestinal barrier function and mislocalization in patients with inflammatory bowel disease. Gastroenterology 143, 122-132.e15 (2012).
-
(2012)
Gastroenterology
, vol.143
-
-
Petit, C.S.1
-
17
-
-
84864811167
-
Cutting edge: Brucella abortus exploits a cellular prion protein on intestinal M cells as an invasive receptor
-
Nakato, G. et al. Cutting edge: Brucella abortus exploits a cellular prion protein on intestinal M cells as an invasive receptor. J. Immunol. 189, 1540-1544 (2012).
-
(2012)
J. Immunol.
, vol.189
, pp. 1540-1544
-
-
Nakato, G.1
-
18
-
-
84888124305
-
SIRP polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells
-
Nuvolone, M. et al. SIRP polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells. J. Exp. Med. http://dx.doi.org/10.1084/ jem.20131274 (2013).
-
(2013)
J. Exp. Med.
-
-
Nuvolone, M.1
-
19
-
-
14644399854
-
The cellular prion protein modulates phagocytosis and inflammatory response
-
DOI 10.1189/jlb.1103531
-
de Almeida, C. J. et al. The cellular prion protein modulates phagocytosis and inflammatory response. J. Leukoc. Biol. 77, 238-246 (2005). (Pubitemid 40315058)
-
(2005)
Journal of Leukocyte Biology
, vol.77
, Issue.2
, pp. 238-246
-
-
De Almeida, C.J.G.1
Chiarini, L.B.2
Pereira Da Silva, J.3
Silva, P.M.R.4
Martins, M.A.5
Linden, R.6
-
20
-
-
0027332116
-
Conversion of-helices into-sheets features in the formation of the scrapie prion proteins
-
USA
-
Pan, K. M. et al. Conversion of-helices into-sheets features in the formation of the scrapie prion proteins. Proc. Natl Acad. Sci. USA 90, 10962-10966 (1993).
-
(1993)
Proc. Natl Acad. Sci.
, vol.90
, pp. 10962-10966
-
-
Pan, K.M.1
-
21
-
-
77649213673
-
Generating a prion with bacterially expressed recombinant prion protein
-
Wang, F., Wang, X., Yuan, C. G. & Ma, J. Generating a prion with bacterially expressed recombinant prion protein. Science 327, 1132-1135 (2010).
-
(2010)
Science
, vol.327
, pp. 1132-1135
-
-
Wang, F.1
Wang, X.2
Yuan, C.G.3
Ma, J.4
-
22
-
-
0024580902
-
Pathogenesis of scrapie in mice after intragastric infection
-
DOI 10.1016/0168-1702(89)90040-3
-
Kimberlin, R. H. & Walker, C. A. Pathogenesis of scrapie in mice after intragastric infection. Virus Res. 12, 213-220 (1989). (Pubitemid 19088147)
-
(1989)
Virus Research
, vol.12
, Issue.3
, pp. 213-220
-
-
Kimberlin, R.H.1
Walker, C.A.2
-
23
-
-
0037377727
-
Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytes
-
Prinz, M. et al. Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytes. Am. J. Pathol. 162, 1103-1111 (2003). (Pubitemid 36350656)
-
(2003)
American Journal of Pathology
, vol.162
, Issue.4
, pp. 1103-1111
-
-
Prinz, M.1
Huber, G.2
Macpherson, A.J.S.3
Heppner, F.L.4
Glatzel, M.5
Eugster, H.-P.6
Wagner, N.7
Aguzzi, A.8
-
24
-
-
58849129829
-
Bacterial colitis increases susceptibility to oral prion disease
-
Sigurdson, C. J. et al. Bacterial colitis increases susceptibility to oral prion disease. J. Infect. Dis. 199, 243-252 (2009).
-
(2009)
J. Infect. Dis.
, vol.199
, pp. 243-252
-
-
Sigurdson, C.J.1
-
25
-
-
0034797467
-
Transepithelial prion transport by M cells
-
Heppner, F. L. et al. Transepithelial prion transport by M cells. Nature Med. 7, 976-977 (2001).
-
(2001)
Nature Med.
, vol.7
, pp. 976-977
-
-
Heppner, F.L.1
-
26
-
-
84857212312
-
M cell-depletion blocks oral prion disease pathogenesis
-
Donaldson, D. S. et al. M cell-depletion blocks oral prion disease pathogenesis. Mucosal Immunol. 5, 216-225 (2012).
-
(2012)
Mucosal Immunol.
, vol.5
, pp. 216-225
-
-
Donaldson, D.S.1
-
27
-
-
84855290942
-
Prion uptake in the gut: Identification of the first uptake and replication sites
-
Kujala, P. et al. Prion uptake in the gut: identification of the first uptake and replication sites. PLoS Pathog. 7, e1002449 (2011).
-
(2011)
PLoS Pathog.
, vol.7
-
-
Kujala, P.1
-
28
-
-
0019813515
-
In vitro interaction of scrapie agent and mouse peritoneal macrophages
-
Carp, R. I. & Callahan, S. M. In vitro interaction of scrapie agent and mouse peritoneal macrophages. Intervirology 16, 8-13 (1981). (Pubitemid 12200956)
-
(1981)
Intervirology
, vol.16
, Issue.1
, pp. 8-13
-
-
Carp, R.I.1
Callahan, S.M.2
-
29
-
-
0034068675
-
Role of spleen macrophages in the clearance of scrapie agent early in pathogenesis
-
DOI 10.1002/(SICI)1096-9896(200003)190:4<495::AID-PATH535>3.0.CO;2- T
-
Beringue, V. et al. Role of spleen macrophages in the clearance of scrapie agent early in pathogenesis. J. Pathol. 190, 495-502 (2000). (Pubitemid 30163592)
-
(2000)
Journal of Pathology
, vol.190
, Issue.4
, pp. 495-502
-
-
Beringue, V.1
Demoy, M.2
Lasmezas, C.I.3
Gouritin, B.4
Weingarten, C.5
Deslys, J.-P.6
Andreux, J.-P.7
Couvreur, P.8
Dormont, D.9
-
30
-
-
0036135693
-
Sc from the gut
-
Huang, F. P., Farquhar, C. F., Mabbott, N. A., Bruce, M. E. & MacPherson, G. G. Migrating intestinal dendritic cells transport PrPSc from the gut. J. Gen. Virol. 83, 267-271 (2002). (Pubitemid 34030831)
-
(2002)
Journal of General Virology
, vol.83
, Issue.1
, pp. 267-271
-
-
Huang, F.-P.1
Farquhar, C.F.2
Mabbott, N.A.3
Bruce, M.E.4
MacPherson, G.G.5
-
31
-
-
38849196274
-
In vivo depletion of CD11c+ cells impairs scrapie agent neuroinvasion from the intestine
-
Raymond, C. R., Aucouturier, P. & Mabbott, N. A. In vivo depletion of CD11c+ cells impairs scrapie agent neuroinvasion from the intestine. J. Immunol. 179, 7758-7766 (2007).
-
(2007)
J. Immunol.
, vol.179
, pp. 7758-7766
-
-
Raymond, C.R.1
Aucouturier, P.2
Mabbott, N.A.3
-
32
-
-
0034675211
-
Transmission of BSE by blood transfusion in sheep
-
Houston, F., Foster, J. D., Chong, A., Hunter, N. & Bostock, C. J. Transmission of BSE by blood transfusion in sheep. Lancet 356, 999-1000 (2000).
-
(2000)
Lancet
, vol.356
, pp. 999-1000
-
-
Houston, F.1
Foster, J.D.2
Chong, A.3
Hunter, N.4
Bostock, C.J.5
-
33
-
-
33749618609
-
Infectious prions in the saliva and blood of deer with chronic wasting disease
-
DOI 10.1126/science.1132661
-
Mathiason, C. K. et al. Infectious prions in the saliva and blood of deer with chronic wasting disease. Science 314, 133-136 (2006). (Pubitemid 44547758)
-
(2006)
Science
, vol.314
, Issue.5796
, pp. 133-136
-
-
Mathiason, C.K.1
Powers, J.G.2
Dahmes, S.J.3
Osborn, D.A.4
Miller, K.V.5
Warren, R.J.6
Mason, G.L.7
Hays, S.A.8
Hayes-Klug, J.9
Seelig, D.M.10
Wild, M.A.11
Wolfe, L.L.12
Spraker, T.R.13
Miller, M.W.14
Sigurdson, C.J.15
Telling, G.C.16
Hoover, E.A.17
-
34
-
-
0033608367
-
Surgical treatment and risk of sporadic Creutzfeldt-Jakob disease: A case-control study
-
DOI 10.1016/S0140-6736(98)08138-0
-
Collins, S. et al. Surgical treatment and risk of sporadic Creutzfeldt-Jakob disease: a case-control study. Lancet 353, 693-697 (1999). (Pubitemid 29103801)
-
(1999)
Lancet
, vol.353
, Issue.9154
, pp. 693-697
-
-
Collins, S.1
Law, M.G.2
Fletcher, A.3
Boyd, A.4
Kaldor, J.5
Masters, C.L.6
-
35
-
-
0020484643
-
Transmission of scrapie by oral route: Effect of gingival scarification
-
Carp, R. I. Transmission of scrapie by oral route: effect of gingival scarification. Lancet 1, 170-171 (1982).
-
(1982)
Lancet
, vol.1
, pp. 170-171
-
-
Carp, R.I.1
-
36
-
-
3242768388
-
Scrapie transmission following exposure through the skin is dependent on follicular dendritic cells in lymphoid tissues
-
DOI 10.1016/j.jdermsci.2004.05.005, PII S0923181104000994
-
Mohan, J., Brown, K. L., Farquhar, C. F., Bruce, M. E. & Mabbott, N. A. Scrapie transmission following exposure through the skin is dependent on follicular dendritic cells in lymphoid tissues. J. Dermatol. Sci. 35, 101-111 (2004). (Pubitemid 38969033)
-
(2004)
Journal of Dermatological Science
, vol.35
, Issue.2
, pp. 101-111
-
-
Mohan, J.1
Brown, K.L.2
Farquhar, C.F.3
Bruce, M.E.4
Mabbott, N.A.5
-
37
-
-
33847610656
-
Role of the draining lymph node in scrapie agent transmission from the skin
-
DOI 10.1016/j.imlet.2007.01.003, PII S0165247807000077
-
Glaysher, B. R. & Mabbott, N. A. Role of the draining lymph node in scrapie agent transmission from the skin. Immunol. Lett. 109, 64-71 (2007). (Pubitemid 46365968)
-
(2007)
Immunology Letters
, vol.109
, Issue.1
, pp. 64-71
-
-
Glaysher, B.R.1
Mabbott, N.A.2
-
38
-
-
84873037260
-
Aerosol transmission of chronic wasting disease in white-tailed deer
-
Denkers, N. D. et al. Aerosol transmission of chronic wasting disease in white-tailed deer. J. Virol. 87, 1890-1892 (2013).
-
(2013)
J. Virol.
, vol.87
, pp. 1890-1892
-
-
Denkers, N.D.1
-
39
-
-
79551523008
-
Aerosols transmit prions to immunocompetent and immunodeficient mice
-
Haybaeck, J. et al. Aerosols transmit prions to immunocompetent and immunodeficient mice. PLoS Pathog. 7, e1001257 (2011).
-
(2011)
PLoS Pathog.
, vol.7
-
-
Haybaeck, J.1
-
40
-
-
84877324595
-
Intranasal inoculation of white-tailed deer (Odocoileus virginianus) with lyophilized chronic wasting disease prion particulate complexed to montmorillonite clay
-
Nichols, T. A. et al. Intranasal inoculation of white-tailed deer (Odocoileus virginianus) with lyophilized chronic wasting disease prion particulate complexed to montmorillonite clay. PLoS ONE 8, e62455 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
Nichols, T.A.1
-
41
-
-
84869211903
-
Rapid transepithelial transport of prions following inhalation
-
Kincaid, A. E., Hudson, K. F., Richey, M. W. & Bartz, J. C. Rapid transepithelial transport of prions following inhalation. J. Virol. 86, 12731-12740 (2012).
-
(2012)
J. Virol.
, vol.86
, pp. 12731-12740
-
-
Kincaid, A.E.1
Hudson, K.F.2
Richey, M.W.3
Bartz, J.C.4
-
42
-
-
0001530885
-
Further observations on the experimental production of scrapie in goats and sheep
-
Pattison, I. H. & Millson, G. C. Further observations on the experimental production of scrapie in goats and sheep. J. Comp. Pathol. 70, 182-193 (1960).
-
(1960)
J. Comp. Pathol.
, vol.70
, pp. 182-193
-
-
Pattison, I.H.1
Millson, G.C.2
-
43
-
-
0032883356
-
Oral transmission and early lymphoid tropism of chronic wasting disease PrP(res) in mule deer fawns (Odocoileus hemionus)
-
Sigurdson, C. J. et al. Oral transmission and early lymphoid tropism of chronic wasting disease PrPres in mule deer fawns (Odocoileus hemionus). J. Gen. Virol. 80, 2757-2764 (1999). (Pubitemid 29458640)
-
(1999)
Journal of General Virology
, vol.80
, Issue.10
, pp. 2757-2764
-
-
Sigurdson, C.J.1
Williams, E.S.2
Miller, M.W.3
Spraker, T.R.4
O'Rourke, K.I.5
Hoover, E.A.6
-
44
-
-
0023257047
-
Temporal distribution of transmissible mink encephalopathy virus in mink inoculated subcutaneously
-
Hadlow, W. J., Race, R. E. & Kennedy, R. C. Temporal distribution of transmissible mink encephalopathy virus in mink inoculated subcutaneously. J. Virol. 61, 3235-3240 (1987). (Pubitemid 17137678)
-
(1987)
Journal of Virology
, vol.61
, Issue.10
, pp. 3235-3240
-
-
Hadlow, W.J.1
Race, R.E.2
Kennedy, R.C.3
-
45
-
-
0032578283
-
Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease
-
Hilton, D. A., Fathers, E., Edwards, P., Ironside, J. W. & Zajicek, J. Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease. Lancet 352, 703-704 (1998).
-
(1998)
Lancet
, vol.352
, pp. 703-704
-
-
Hilton, D.A.1
Fathers, E.2
Edwards, P.3
Ironside, J.W.4
Zajicek, J.5
-
46
-
-
0023095066
-
Lack of effect of thymus and spleen on the incubation period of Creutzfeldt-Jakob disease in mice
-
Mohri, S., Handa, S. & Tateishi, J. Lack of effect of thymus and spleen on the incubation period of Creutzfeldt-Jakob disease in mice. J. Gen. Virol. 68, 1187-1189 (1987). (Pubitemid 17043528)
-
(1987)
Journal of General Virology
, vol.68
, Issue.4
, pp. 1187-1189
-
-
Mohri, S.1
Handa, S.2
Tateishi, J.3
-
47
-
-
84856306158
-
Facilitated cross-species transmission of prions in extraneural tissue
-
Beringue, V. et al. Facilitated cross-species transmission of prions in extraneural tissue. Science 335, 472-475 (2012).
-
(2012)
Science
, vol.335
, pp. 472-475
-
-
Beringue, V.1
-
48
-
-
0031015906
-
Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy
-
DOI 10.1016/S0140-6736(97)24002-X
-
Hill, A. F., Zeidler, M., Ironside, J. & Collinge, J. Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy. Lancet 349, 99-100 (1997). (Pubitemid 27023429)
-
(1997)
Lancet
, vol.349
, Issue.9045
, pp. 99-100
-
-
Hill, A.F.1
Zeidler, M.2
Ironside, J.3
Collinge, J.4
-
49
-
-
0014930050
-
Pathogenesis of scrapie in the mouse: The role of the spleen
-
Fraser, H. & Dickinson, A. G. Pathogenesis of scrapie in the mouse: the role of the spleen. Nature 226, 462-463 (1970).
-
(1970)
Nature
, vol.226
, pp. 462-463
-
-
Fraser, H.1
Dickinson, A.G.2
-
50
-
-
0015026826
-
Multiplication of scrapie agent in mouse spleen
-
Clarke, M. C. & Haig, D. A. Multiplication of scrapie agent in mouse spleen. Res. Vet. Sci. 12, 195-197 (1971).
-
(1971)
Res. Vet. Sci.
, vol.12
, pp. 195-197
-
-
Clarke, M.C.1
Haig, D.A.2
-
51
-
-
0024519176
-
The role of the spleen in the neuroinvasion of scrapie in mice
-
Kimberlin, R. H. & Walker, C. A. The role of the spleen in the neuroinvasion of scrapie in mice. Virus Res. 12, 201-211 (1989).
-
(1989)
Virus Res.
, vol.12
, pp. 201-211
-
-
Kimberlin, R.H.1
Walker, C.A.2
-
52
-
-
0025983158
-
Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease
-
Kitamoto, T., Muramoto, T., Mohri, S., Doh-Ura, K. & Tateishi, J. Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease. J. Virol. 65, 6292-6295 (1991).
-
(1991)
J. Virol.
, vol.65
, pp. 6292-6295
-
-
Kitamoto, T.1
Muramoto, T.2
Mohri, S.3
Doh-Ura, K.4
Tateishi, J.5
-
53
-
-
0030030927
-
Immune system-dependent and -independent replication of the scrapie agent
-
Lasmezas, C. I. et al. Immune system-dependent and-independent replication of the scrapie agent. J. Virol. 70, 1292-1295 (1996). (Pubitemid 26029059)
-
(1996)
Journal of Virology
, vol.70
, Issue.2
, pp. 1292-1295
-
-
Lasmezas, C.I.1
Cesbron, J.-Y.2
Deslys, J.-P.3
Demaimay, R.4
Adjou, K.T.5
Rioux, R.6
Lemaire, C.7
Locht, C.8
Dormont, D.9
-
54
-
-
0030728435
-
Severely combined immunodeficient (SCID) mice resist infection with bovine spongiform encephalopathy
-
Brown, K. L., Stewart, K., Bruce, M. E. & Fraser, H. Severely combined immunodeficient (SCID) mice resist infection with bovine spongiform encephalopathy. J. Gen. Virol. 78, 2707-2710 (1997). (Pubitemid 27470016)
-
(1997)
Journal of General Virology
, vol.78
, Issue.10
, pp. 2707-2710
-
-
Brown, K.L.1
Stewart, K.2
Bruce, M.E.3
Fraser, H.4
-
55
-
-
0015301828
-
Isolation from mouse spleen of cell populations with high specific infectivity for scrapie virus
-
Lavelle, G. C., Sturman, L. & Hadlow, W. J. Isolation from mouse spleen of cell populations with high specific infectivity for scrapie virus. Infect. Immun. 5, 319-323 (1972).
-
(1972)
Infect. Immun.
, vol.5
, pp. 319-323
-
-
Lavelle, G.C.1
Sturman, L.2
Hadlow, W.J.3
-
56
-
-
0021212843
-
Pathogenesis of mouse scrapie: Distribution of agent in the pulp and stroma of infected spleens
-
DOI 10.1016/0378-1135(84)90039-7
-
Clarke, M. C. & Kimberlin, R. H. Pathogenesis of mouse scrapie: distribution of agent in the pulp and stroma of infected spleens. Vet. Microbiol. 9, 215-225 (1984). (Pubitemid 14069466)
-
(1984)
Veterinary Microbiology
, vol.9
, Issue.3
, pp. 215-225
-
-
Clarke, M.C.1
Kimberlin, R.H.2
-
57
-
-
0023094630
-
Ionising radiation has no influence on scrapie incubation period in mice
-
DOI 10.1016/0378-1135(87)90084-8
-
Fraser, H. & Farquhar, C. F. Ionising radiation has no influence on scrapie incubation period in mice. Vet. Microbiol. 13, 211-223 (1987). (Pubitemid 17041374)
-
(1987)
Veterinary Microbiology
, vol.13
, Issue.3
, pp. 211-223
-
-
Fraser, H.1
Farquhar, C.F.2
-
58
-
-
0031444295
-
A crucial role for B cells in neuroinvasive scraple
-
DOI 10.1038/37789
-
Klein, M. A. et al. A crucial role for B cells in neuroinvasive scrapie. Nature 390, 687-690 (1997). (Pubitemid 28016356)
-
(1997)
Nature
, vol.390
, Issue.6661
, pp. 687-690
-
-
Klein, M.A.1
Frigg, R.2
Flechsig, E.3
Raeber, A.J.4
Kalinke, U.5
Bluethmann, H.6
Bootz, F.7
Suter, M.8
Zinkernagel, R.M.9
Aguzzi, A.10
-
59
-
-
0027319326
-
Mice devoid of PrP are resistant to scrapie
-
DOI 10.1016/0092-8674(93)90360-3
-
Bueler, H. et al. Mice devoid of PrP are resistant to scrapie. Cell 73, 1339-1347 (1993). (Pubitemid 23201147)
-
(1993)
Cell
, vol.73
, Issue.7
, pp. 1339-1347
-
-
Bueler, H.1
Aguzzi, A.2
Sailer, A.3
Greiner, R.-A.4
Autenried, P.5
Aguet, M.6
Weissmann, C.7
-
60
-
-
0031759918
-
PrP expression in B lymphocytes is not required for prion neuroinvasion
-
DOI 10.1038/4022
-
Klein, M. A. et al. PrP expression in B lymphocytes is not required for prion neuroinvasion. Nature Med. 4, 1429-1433 (1998). (Pubitemid 28553468)
-
(1998)
Nature Medicine
, vol.4
, Issue.12
, pp. 1429-1433
-
-
Klein, M.A.1
Frigg, R.2
Raeber, A.J.3
Flechsig, E.4
Hegyi, I.5
Zinkernagel, R.M.6
Weissmann, C.7
Aguzzi, A.8
-
61
-
-
0035957340
-
B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout mice
-
DOI 10.1073/pnas.051609398
-
Montrasio, F. et al. B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout mice. Proc. Natl Acad. Sci. USA 98, 4034-4037 (2001). (Pubitemid 32249893)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.7
, pp. 4034-4037
-
-
Montrasio, F.1
Cozzio, A.2
Flechsig, E.3
Rossi, D.4
Klein, M.A.5
Rulicke, T.6
Raeber, A.J.7
Vosshenrich, C.A.J.8
Proft, J.9
Aguzzi, A.10
Weissmann, C.11
-
62
-
-
0038186806
-
PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain
-
DOI 10.1038/37981
-
Blattler, T. et al. PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain. Nature 389, 69-73 (1997). (Pubitemid 27387692)
-
(1997)
Nature
, vol.389
, Issue.6646
, pp. 69-73
-
-
Blattler, T.1
Brandner, S.2
Raeber, A.J.3
Klein, M.A.4
Voigtlander, T.5
Weissmann, C.6
Aguzzi, A.7
-
63
-
-
0034953560
-
c in stromal and hematopoietic cells
-
DOI 10.1128/JVI.75.15.7097-7106.2001
-
Kaeser, P. S., Klein, M. A., Schwarz, P. & Aguzzi, A. Efficient lymphoreticular prion propagation requires PrPc in stromal and hematopoietic cells. J. Virol. 75, 7097-7106 (2001). (Pubitemid 32641597)
-
(2001)
Journal of Virology
, vol.75
, Issue.15
, pp. 7097-7106
-
-
Kaeser, P.S.1
Klein, M.A.2
Schwarz, P.3
Aguzzi, A.4
-
64
-
-
0032746253
-
Scrapie replication in lymphoid tissues depends on prion protein- expressing follicular dendritic cells
-
DOI 10.1038/15264
-
Brown, K. L. et al. Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells. Nature Med. 5, 1308-1312 (1999). (Pubitemid 29535610)
-
(1999)
Nature Medicine
, vol.5
, Issue.11
, pp. 1308-1312
-
-
Brown, K.L.1
Stewart, K.2
Ritchie, D.L.3
Mabbott, N.A.4
Williams, A.5
Fraser, H.6
Morrison, W.I.7
Bruce, M.E.8
-
65
-
-
78049298674
-
Prion replication in the hematopoietic compartment is not required for neuroinvasion in scrapie mouse model
-
Loeuillet, C. et al. Prion replication in the hematopoietic compartment is not required for neuroinvasion in scrapie mouse model. PLoS ONE 5, e13166 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Loeuillet, C.1
-
66
-
-
84863632660
-
Follicular dendritic cells emerge from ubiquitous perivascular precursors
-
Krautler, N. J. et al. Follicular dendritic cells emerge from ubiquitous perivascular precursors. Cell 150, 194-206 (2012).
-
(2012)
Cell
, vol.150
, pp. 194-206
-
-
Krautler, N.J.1
-
67
-
-
0034686002
-
Impaired prion replication in spleens of mice lacking functional follicular dendritic cells
-
DOI 10.1126/science.288.5469.1257
-
Montrasio, F. et al. Impaired prion replication in spleens of mice lacking functional follicular dendritic cells. Science 288, 1257-1259 (2000). (Pubitemid 30367206)
-
(2000)
Science
, vol.288
, Issue.5469
, pp. 1257-1259
-
-
Montrasio, F.1
Frigg, R.2
Glatzel, M.3
Klein, M.A.4
Mackay, F.5
Aguzzi, A.6
Weissmann, C.7
-
68
-
-
0033930508
-
Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie [2]
-
DOI 10.1038/77401
-
Mabbott, N. A., Mackay, F., Minns, F. & Bruce, M. E. Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie. Nature Med. 6, 719-720 (2000). (Pubitemid 30469392)
-
(2000)
Nature Medicine
, vol.6
, Issue.7
, pp. 719-720
-
-
Mabbott, N.A.1
Mackay, F.2
Minns, F.3
Bruce, M.E.4
-
69
-
-
0036237549
-
Temporary blockade of the tumor necrosis factor receptor signaling pathway impedes the spread of scrapie to the brain
-
DOI 10.1128/JVI.76.10.5131-5139.2002
-
Mabbott, N. A., McGovern, G., Jeffrey, M. & Bruce, M. E. Temporary blockade of the tumor necrosis factor receptor signaling pathway impedes the spread of scrapie to the brain. J. Virol. 76, 5131-5139 (2002). (Pubitemid 34441717)
-
(2002)
Journal of Virology
, vol.76
, Issue.10
, pp. 5131-5139
-
-
Mabbott, N.A.1
McGovern, G.2
Jeffrey, M.3
Bruce, M.E.4
-
70
-
-
0038618854
-
Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility
-
DOI 10.1128/JVI.77.12.6845-6854.2003
-
Mabbott, N. A., Young, J., McConnell, I. & Bruce, M. E. Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility. J. Virol. 77, 6845-6854 (2003). (Pubitemid 36666878)
-
(2003)
Journal of Virology
, vol.77
, Issue.12
, pp. 6845-6854
-
-
Mabbott, N.A.1
Young, J.2
McConnell, I.3
Bruce, M.E.4
-
71
-
-
0037154263
-
Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells
-
DOI 10.1073/pnas.022626399
-
Prinz, M. et al. Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells. Proc. Natl Acad. Sci. USA 99, 919-924 (2002). (Pubitemid 34106611)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.2
, pp. 919-924
-
-
Prinz, M.1
Montrasio, F.2
Klein, M.A.3
Schwarz, P.4
Priller, J.5
Odermatt, B.6
Pfeffer, K.7
Aguzzi, A.8
-
72
-
-
0035047889
-
Complement facilitates early prion pathogenesis
-
DOI 10.1038/86567
-
Klein, M. A. et al. Complement facilitates early prion pathogenesis. Nature Med. 7, 488-492 (2001). (Pubitemid 32298554)
-
(2001)
Nature Medicine
, vol.7
, Issue.4
, pp. 488-492
-
-
Klein, M.A.1
Kaeser, P.S.2
Schwarz, P.3
Weyd, H.4
Xenarios, I.5
Zinkernagel, R.M.6
Carroll, M.C.7
Verbeek, J.S.8
Botto, M.9
Walport, M.J.10
Molina, H.11
Kalinke, U.12
Acha-Orbea, H.13
Aguzzi, A.14
-
73
-
-
0035053039
-
Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie
-
DOI 10.1038/86562
-
Mabbott, N. A., Bruce, M. E., Botto, M., Walport, M. J. & Pepys, M. B. Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie. Nature Med. 7, 485-487 (2001). (Pubitemid 32298553)
-
(2001)
Nature Medicine
, vol.7
, Issue.4
, pp. 485-487
-
-
Mabbott, N.A.1
Bruce, M.E.2
Botto, M.3
Walport, M.J.4
Pepys, M.B.5
-
74
-
-
38449119141
-
Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis
-
Zabel, M. D. et al. Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis. J. Immunol. 179, 6144-6152 (2007).
-
(2007)
J. Immunol.
, vol.179
, pp. 6144-6152
-
-
Zabel, M.D.1
-
75
-
-
84855282475
-
Follicular dendritic cell-specific prion protein (PrP) expression alone is sufficient to sustain prion infection in the spleen
-
McCulloch, L. et al. Follicular dendritic cell-specific prion protein (PrP) expression alone is sufficient to sustain prion infection in the spleen. PLoS Pathog. 7, e1002402 (2011).
-
(2011)
PLoS Pathog.
, vol.7
-
-
McCulloch, L.1
-
76
-
-
13844259181
-
Chronic lymphocytic inflammation specifies the organ tropism of prions
-
DOI 10.1126/science.1106460
-
Heikenwalder, M. et al. Chronic lymphocytic inflammation specifies the organ tropism of prions. Science 307, 1107-1110 (2005). (Pubitemid 40262116)
-
(2005)
Science
, vol.307
, Issue.5712
, pp. 1107-1110
-
-
Heikenwalder, M.1
Zeller, N.2
Seeger, H.3
Prinz, M.4
Klohn, P.-C.5
Schwarz, P.6
Ruddle, N.H.7
Weissmann, C.8
Aguzzi, A.9
-
77
-
-
26844563437
-
Medicine: Coincident scrapie infection and nephritis lead to urinary prion excretion
-
DOI 10.1126/science.1118829
-
Seeger, H. et al. Coincident scrapie infection and nephritis lead to urinary prion excretion. Science 310, 324-326 (2005). (Pubitemid 41457200)
-
(2005)
Science
, vol.310
, Issue.5746
, pp. 324-326
-
-
Seeger, H.1
Heikenwalder, M.2
Zeller, N.3
Kranich, J.4
Schwarz, P.5
Gaspert, A.6
Seifert, B.7
Miele, G.8
Aguzzi, A.9
-
78
-
-
33646455867
-
Abnormal prion protein in ectopic lymphoid tissue in a kidney of an asymptomatic white-tailed deer experimentally inoculated with the agent of chronic wasting disease
-
Hamir, A. N., Kunkle, R. A., Miller, J. M. & Hall, S. M. Abnormal prion protein in ectopic lymphoid tissue in a kidney of an asymptomatic white-tailed deer experimentally inoculated with the agent of chronic wasting disease. Vet. Pathol. 43, 367-369 (2006).
-
(2006)
Vet. Pathol.
, vol.43
, pp. 367-369
-
-
Hamir, A.N.1
Kunkle, R.A.2
Miller, J.M.3
Hall, S.M.4
-
79
-
-
30744466152
-
Sc in mammary glands of sheep affected by scrapie and mastitis [3]
-
DOI 10.1038/nm1105-1137, PII NM11051137
-
Ligios, C. et al. PrPSc in mammary glands of sheep affected by scrapie and mastitis. Nature Med. 11, 1137-1138 (2005). (Pubitemid 43093650)
-
(2005)
Nature Medicine
, vol.11
, Issue.11
, pp. 1137-1138
-
-
Ligios, C.1
Sigurdson, C.J.2
Santucciu, C.3
Carcassola, G.4
Manco, G.5
Basagni, M.6
Maestrale, C.7
Cancedda, M.G.8
Madau, L.9
Aguzzi, A.10
-
80
-
-
58149234376
-
Prions in milk from ewes incubating natural scrapie
-
Lacroux, C. et al. Prions in milk from ewes incubating natural scrapie. PLoS Pathog. 4, e1000238 (2008).
-
(2008)
PLoS Pathog.
, vol.4
-
-
Lacroux, C.1
-
81
-
-
84877015754
-
Evidence of effective scrapie transmission via colostrum and milk in sheep
-
Konold, T. et al. Evidence of effective scrapie transmission via colostrum and milk in sheep. BMC Vet. Res. 9, 99 (2013).
-
(2013)
BMC Vet. Res.
, vol.9
, pp. 99
-
-
Konold, T.1
-
82
-
-
78650664037
-
Sheep with scrapie and mastitis transmit infectious prions through the milk
-
Ligios, C. et al. Sheep with scrapie and mastitis transmit infectious prions through the milk. J. Virol. 85, 1136-1139 (2011).
-
(2011)
J. Virol.
, vol.85
, pp. 1136-1139
-
-
Ligios, C.1
-
83
-
-
84866162526
-
Lymphotoxin, but not TNF, is required for prion invasion of lymph nodes
-
O'Connor, T. et al. Lymphotoxin, but not TNF, is required for prion invasion of lymph nodes. PLoS Pathog. 8, e1002867 (2012).
-
(2012)
PLoS Pathog.
, vol.8
-
-
O'Connor, T.1
-
84
-
-
57449112742
-
Lymphotoxin-dependent prion replication in inflammatory stromal cells of granulomas
-
Heikenwalder, M. et al. Lymphotoxin-dependent prion replication in inflammatory stromal cells of granulomas. Immunity 29, 998-1008 (2008).
-
(2008)
Immunity
, vol.29
, pp. 998-1008
-
-
Heikenwalder, M.1
-
85
-
-
0021808813
-
Pathogenesis of mouse scrapie: Dynamics of vacuolation in brain and spinal cord after intraperitoneal infection
-
Cole, S. & Kimberlin, R. H. Pathogenesis of mouse scrapie: dynamics of vacuolation in brain and spinal cord after intraperitoneal infection. Neuropathol. Appl. Neurobiol. 11, 213-227 (1985). (Pubitemid 15059499)
-
(1985)
Neuropathology and Applied Neurobiology
, vol.11
, Issue.3
, pp. 213-227
-
-
Cole, S.1
Kimberlin, R.H.2
-
86
-
-
0033574604
-
Pathological PrP is abundant in sympathetic and sensory ganglia of hamsters fed with scrapie
-
DOI 10.1016/S0304-3940(99)00223-2, PII S0304394099002232
-
McBride, P. A. & Beekes, M. Pathological PrP is abundant in sympathetic and sensory ganglia of hamsters fed with scrapie. Neurosci. Lett. 265, 135-138 (1999). (Pubitemid 29210387)
-
(1999)
Neuroscience Letters
, vol.265
, Issue.2
, pp. 135-138
-
-
McBride, P.A.1
Beekes, M.2
-
87
-
-
0038325574
-
Disease-associated PrP in the enteric nervous system of scrapie-affected Suffolk sheep
-
DOI 10.1099/vir.0.18874-0
-
Heggebo, R. et al. Disease-associated PrP in the enteric nervous system of scrapie-affected Suffolk sheep. J. Gen. Virol. 84, 1327-1338 (2003). (Pubitemid 36592627)
-
(2003)
Journal of General Virology
, vol.84
, Issue.5
, pp. 1327-1338
-
-
Heggebo, R.1
Gonzalez, L.2
Press, C.McL.3
Gunnes, G.4
Espenes, A.5
Jeffrey, M.6
-
88
-
-
0034891027
-
Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion
-
DOI 10.1016/S0896-6273(01)00331-2
-
Glatzel, M., Heppner, F. L., Albers, K. M. & Aguzzi, A. Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion. Neuron 31, 25-34 (2001). (Pubitemid 32757086)
-
(2001)
Neuron
, vol.31
, Issue.1
, pp. 25-34
-
-
Glatzel, M.1
Heppner, F.L.2
Albers, K.M.3
Aguzzi, A.4
-
89
-
-
28444454236
-
Pathogenesis of natural scrapie in sheep
-
van Keulen, L. J., Schreuder, B. E., Vromans, M. E., Langeveld, J. P. & Smits, M. A. Pathogenesis of natural scrapie in sheep. Arch. Virol. Suppl. 16, 57-71 (2000). (Pubitemid 33757365)
-
(2001)
Archives of Virology, Supplement
, Issue.16
, pp. 57-71
-
-
Van Keulen, L.J.M.1
Schreuder, B.E.C.2
Vromans, M.E.W.3
Langeveld, J.P.M.4
Smits, M.A.5
-
90
-
-
0034784808
-
CWD in the myenteric plexus, vagosympathetic trunk and endocrine glands of deer with chronic wasting disease
-
Sigurdson, C. J., Spraker, T. R., Miller, M. W., Oesch, B. & Hoover, E. A. PrP(CWD) in the myenteric plexus, vagosympathetic trunk and endocrine glands of deer with chronic wasting disease. J. Gen. Virol. 82, 2327-2334 (2001). (Pubitemid 32936766)
-
(2001)
Journal of General Virology
, vol.82
, Issue.10
, pp. 2327-2334
-
-
Sigurdson, C.J.1
Spraker, T.R.2
Miller, M.W.3
Oesch, B.4
Hoover, E.A.5
-
91
-
-
0141573165
-
The sympathetic nervous system is involved in variant Creutzfeldt-Jakob disease
-
DOI 10.1038/nm922
-
Haik, S. et al. The sympathetic nervous system is involved in variant Creutzfeldt-Jakob disease. Nature Med. 9, 1121-1123 (2003). (Pubitemid 37173693)
-
(2003)
Nature Medicine
, vol.9
, Issue.9
, pp. 1121-1123
-
-
Haik, S.1
Faucheux, B.A.2
Sazdovitch, V.3
Privat, N.4
Kemeny, J.-L.5
Perret-Liaudet, A.6
Hauw, J.-J.7
-
92
-
-
0242499506
-
Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion
-
DOI 10.1038/nature02072
-
Prinz, M. et al. Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion. Nature 425, 957-962 (2003). (Pubitemid 37376926)
-
(2003)
Nature
, vol.425
, Issue.6961
, pp. 957-962
-
-
Prinz, M.1
Helkenwalder, M.2
Junt, T.3
Schwarz, P.4
Glatzel, M.5
Heppner, F.L.6
Fu, Y.-X.7
Lipp, M.8
Aguzzi, A.9
-
93
-
-
3042788972
-
Cells release prions in association with exosomes
-
DOI 10.1073/pnas.0308413101
-
Fevrier, B. et al. Cells release prions in association with exosomes. Proc. Natl Acad. Sci. USA 101, 9683-9688 (2004). (Pubitemid 38869296)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.26
, pp. 9683-9688
-
-
Fevrier, B.1
Vilette, D.2
Archer, F.3
Loew, D.4
Faigle, W.5
Vidal, M.6
Laude, H.7
Raposo, G.8
-
94
-
-
61849178720
-
Prions hijack tunnelling nanotubes for intercellular spread
-
Gousset, K. et al. Prions hijack tunnelling nanotubes for intercellular spread. Nature Cell Biol. 11, 328-336 (2009).
-
(2009)
Nature Cell Biol.
, vol.11
, pp. 328-336
-
-
Gousset, K.1
-
95
-
-
24644448839
-
The most infectious prion protein particles
-
DOI 10.1038/nature03989
-
Silveira, J. R. et al. The most infectious prion protein particles. Nature 437, 257-261 (2005). (Pubitemid 41294488)
-
(2005)
Nature
, vol.437
, Issue.7056
, pp. 257-261
-
-
Silveira, J.R.1
Raymond, G.J.2
Hughson, A.G.3
Race, R.E.4
Sim, V.L.5
Hayes, S.F.6
Caughey, B.7
-
96
-
-
0036091743
-
Retrograde transport of transmissible mink encephalopathy within descending motor tracts
-
DOI 10.1128/JVI.76.11.5759-5768.2002
-
Bartz, J. C., Kincaid, A. E. & Bessen, R. A. Retrograde transport of transmissible mink encephalopathy within descending motor tracts. J. Virol. 76, 5759-5768 (2002). (Pubitemid 34517926)
-
(2002)
Journal of Virology
, vol.76
, Issue.11
, pp. 5759-5768
-
-
Bartz, J.C.1
Kincaid, A.E.2
Bessen, R.A.3
-
97
-
-
55249083798
-
Accelerated prion disease pathogenesis in toll-like receptor 4 signaling-mutant mice
-
DOI 10.1128/JVI.00522-08
-
Spinner, D. S. et al. Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice. J. Virol. 82, 10701-10708 (2008). (Pubitemid 352691158)
-
(2008)
Journal of Virology
, vol.82
, Issue.21
, pp. 10701-10708
-
-
Spinner, D.S.1
In, S.C.2
Seung, Y.P.3
Jae, I.K.4
Meeker, H.C.5
Ye, X.6
LaFauci, G.7
Kerr, D.J.8
Flory, M.J.9
Bo, S.K.10
Kascsak, R.B.11
Wisniewski, T.12
Levis, W.R.13
Schuller-Levis, G.B.14
Carp, R.I.15
Park, E.16
Kascsak, R.J.17
-
98
-
-
84861302844
-
Protective role of interferon regulatory factor 3-mediated signaling against prion infection
-
Ishibashi, D. et al. Protective role of interferon regulatory factor 3-mediated signaling against prion infection. J. Virol. 86, 4947-4955 (2012).
-
(2012)
J. Virol.
, vol.86
, pp. 4947-4955
-
-
Ishibashi, D.1
-
99
-
-
0037297956
-
Prion pathogenesis in the absence of Toll-like receptor signalling
-
DOI 10.1038/sj.embor.embor731
-
Prinz, M. et al. Prion pathogenesis in the absence of Toll-like receptor signalling. EMBO Rep. 4, 195-199 (2003). (Pubitemid 36322162)
-
(2003)
EMBO Reports
, vol.4
, Issue.2
, pp. 195-199
-
-
Prinz, M.1
Heikenwalder, M.2
Schwarz, P.3
Takeda, K.4
Akira, S.5
Aguzzi, A.6
-
100
-
-
0015843553
-
Failure to demonstrate a humoral immune response to scrapie infection in mice
-
Porter, D. D., Porter, H. G. & Cox, N. A. Failure to demonstrate a humoral immune response to scrapie infection in mice. J. Immunol. 111, 1407-1410 (1973).
-
(1973)
J. Immunol.
, vol.111
, pp. 1407-1410
-
-
Porter, D.D.1
Porter, H.G.2
Cox, N.A.3
-
101
-
-
1442302400
-
Murine scrapie infection causes an abnormal germinal centre reaction in the spleen
-
DOI 10.1016/j.jcpa.2003.11.001
-
McGovern, G., Brown, K. L., Bruce, M. E. & Jeffrey, M. Murine scrapie infection causes an abnormal germinal centre reaction in the spleen. J. Comp. Pathol. 130, 181-194 (2004). (Pubitemid 38279335)
-
(2004)
Journal of Comparative Pathology
, vol.130
, Issue.2-3
, pp. 181-194
-
-
McGovern, G.1
Brown, K.L.2
Bruce, M.E.3
Jeffrey, M.4
-
102
-
-
0019508185
-
Evidence for normal cell-mediated immunity in scrapie-infected mice
-
Kingsbury, D. T., Smeltzer, D. A., Gibbs, C. J. Jr & Gajdusek, D. C. Evidence for normal cell-mediated immunity in scrapie-infected mice. Infect. Immun. 32, 1176-1180 (1981). (Pubitemid 11109825)
-
(1981)
Infection and Immunity
, vol.32
, Issue.3
, pp. 1176-1180
-
-
Kingsbury, D.T.1
Smeltzer, D.A.2
Gibbs Jr., C.J.3
Gajdusek, D.C.4
-
103
-
-
0034099095
-
Tumor necrosis factor alpha-deficient, but not interleukin-6-deficient, mice resist peripheral infection with scrapie
-
DOI 10.1128/JVI.74.7.3338-3344.2000
-
Mabbott, N. A. et al. Tumor necrosis factor alpha-deficient, but not interleukin-6-deficient, mice resist peripheral infection with scrapie. J. Virol. 74, 3338-3344 (2000). (Pubitemid 30143759)
-
(2000)
Journal of Virology
, vol.74
, Issue.7
, pp. 3338-3344
-
-
Mabbott, N.A.1
Williams, A.2
Farquhar, C.F.3
Pasparakis, M.4
Kollias, G.5
Bruce, M.E.6
-
104
-
-
36749084554
-
Germinal center B cells are dispensable in prion transport and neuroinvasion
-
DOI 10.1016/j.jneuroim.2007.09.022, PII S016557280700327X
-
Heikenwalder, M. et al. Germinal center B cells are dispensable in prion transport and neuroinvasion. J. Neuroimmunol. 192, 113-123 (2007). (Pubitemid 350213123)
-
(2007)
Journal of Neuroimmunology
, vol.192
, Issue.1-2
, pp. 113-123
-
-
Heikenwalder, M.1
Federau, C.2
Boehmer, L.V.3
Schwarz, P.4
Wagner, M.5
Zeller, N.6
Haybaeck, J.7
Prinz, M.8
Becher, B.9
Aguzzi, A.10
-
105
-
-
0027257501
-
Immunohistochemical study of microglia in the Creutzfeldt-Jakob diseased brain
-
Sasaki, A., Hirato, J. & Nakazato, Y. Immunohistochemical study of microglia in the Creutzfeldt-Jakob diseased brain. Acta Neuropathol. 86, 337-344 (1993). (Pubitemid 23280115)
-
(1993)
Acta Neuropathologica
, vol.86
, Issue.4
, pp. 337-344
-
-
Sasaki, A.1
Hirato, J.2
Nakazato, Y.3
-
106
-
-
0028216058
-
Characterization of the microglial response in murine scrapie
-
Williams, A. E., Lawson, L. J., Perry, V. H. & Fraser, H. Characterization of the microglial response in murine scrapie. Neuropathol. Appl. Neurobiol. 20, 47-55 (1994). (Pubitemid 24078165)
-
(1994)
Neuropathology and Applied Neurobiology
, vol.20
, Issue.1
, pp. 47-55
-
-
Williams, A.E.1
Lawson, L.J.2
Perry, V.H.3
Fraser, H.4
-
107
-
-
84870843645
-
Prion pathogenesis is faithfully reproduced in cerebellar organotypic slice cultures
-
Falsig, J. et al. Prion pathogenesis is faithfully reproduced in cerebellar organotypic slice cultures. PLoS Pathog. 8, e1002985 (2012).
-
(2012)
PLoS Pathog.
, vol.8
-
-
Falsig, J.1
-
108
-
-
37549043842
-
A versatile prion replication assay in organotypic brain slices
-
Falsig, J. et al. A versatile prion replication assay in organotypic brain slices. Nature Neurosci. 11, 109-117 (2008).
-
(2008)
Nature Neurosci.
, vol.11
, pp. 109-117
-
-
Falsig, J.1
-
109
-
-
77957733643
-
Engulfment of cerebral apoptotic bodies controls the course of prion disease in a mouse strain-dependent manner
-
Kranich, J. et al. Engulfment of cerebral apoptotic bodies controls the course of prion disease in a mouse strain-dependent manner. J. Exp. Med. 207, 2271-2281 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2271-2281
-
-
Kranich, J.1
-
110
-
-
78649434414
-
Microglia in the degenerating brain are capable of phagocytosis of beads and of apoptotic cells, but do not efficiently remove PrPSc, even upon LPS stimulation
-
Hughes, M. M., Field, R. H., Perry, V. H., Murray, C. L. & Cunningham, C. Microglia in the degenerating brain are capable of phagocytosis of beads and of apoptotic cells, but do not efficiently remove PrPSc, even upon LPS stimulation. Glia 58, 2017-2030 (2010).
-
(2010)
Glia
, vol.58
, pp. 2017-2030
-
-
Hughes, M.M.1
Field, R.H.2
Perry, V.H.3
Murray, C.L.4
Cunningham, C.5
-
111
-
-
0032895529
-
Heightened intrathecal release of proinflammatory cytokines in Creutzfeldt-Jakob disease
-
Sharief, M. K., Green, A., Dick, J. P., Gawler, J. & Thompson, E. J. Heightened intrathecal release of proinflammatory cytokines in Creutzfeldt-Jakob disease. Neurology 52, 1289-1291 (1999). (Pubitemid 29177941)
-
(1999)
Neurology
, vol.52
, Issue.6
, pp. 1289-1291
-
-
Sharief, M.K.1
Green, A.2
Dick, J.P.R.3
Gawler, J.4
Thompson, E.J.5
-
112
-
-
0028203591
-
Activation of cerebral cytokine gene expression and its correlation with onset of reactive astrocyte and acute-phase response gene expression in scrapie
-
Campbell, I. L., Eddleston, M., Kemper, P., Oldstone, M. B. & Hobbs, M. V. Activation of cerebral cytokine gene expression and its correlation with onset of reactive astrocyte and acute-phase response gene expression in scrapie. J. Virol. 68, 2383-2387 (1994). (Pubitemid 24091917)
-
(1994)
Journal of Virology
, vol.68
, Issue.4
, pp. 2383-2387
-
-
Campbell, I.L.1
Eddleston, M.2
Kemper, P.3
Oldstone, M.B.A.4
Hobbs, M.V.5
-
113
-
-
0029817787
-
Heightened expression of tumor necrosis factor α, interleukin 1α, and glial fibrillary acidic protein in experimental Creutzfeldt-Jakob disease in mice
-
DOI 10.1073/pnas.93.18.9754
-
Kordek, R. et al. Heightened expression of tumor necrosis factor-, interleukin-, and glial fibrillary acidic protein in experimental Creutzfeldt-Jakob disease in mice. Proc. Natl Acad. Sci. USA 93, 9754-9758 (1996). (Pubitemid 26296681)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.18
, pp. 9754-9758
-
-
Kordek, R.1
Nerurkar, V.R.2
Liberski, P.P.3
Isaacson, S.4
Yanagihara, R.5
Gajdusek, D.C.6
-
114
-
-
0035111243
-
Absence of detectable IL-1β production in murine prion disease: A model of chronic neurodegeneration
-
Walsh, D. T., Betmouni, S. & Perry, V. H. Absence of detectable IL-1 production in murine prion disease: a model of chronic neurodegeneration. J. Neuropathol. Exp. Neurol. 60, 173-182 (2001). (Pubitemid 32172420)
-
(2001)
Journal of Neuropathology and Experimental Neurology
, vol.60
, Issue.2
, pp. 173-182
-
-
Walsh, D.T.1
Betmouni, S.2
Perry, V.H.3
-
115
-
-
0345188622
-
Microglial activation varies in different models of Creutzfeldt-Jakob disease
-
Baker, C. A., Lu, Z. Y., Zaitsev, I. & Manuelidis, L. Microglial activation varies in different models of Creutzfeldt-Jakob disease. J. Virol. 73, 5089-5097 (1999). (Pubitemid 29246771)
-
(1999)
Journal of Virology
, vol.73
, Issue.6
, pp. 5089-5097
-
-
Baker, C.A.1
Lu, Z.Y.2
Zaitsev, I.3
Manuelidis, L.4
-
116
-
-
26444558113
-
Interleukin 4 and interleukin 10 levels are elevated in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease
-
DOI 10.1001/archneur.62.10.1591
-
Stoeck, K. et al. Interleukin 4 and interleukin 10 levels are elevated in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Arch. Neurol. 62, 1591-1594 (2005). (Pubitemid 41434566)
-
(2005)
Archives of Neurology
, vol.62
, Issue.10
, pp. 1591-1594
-
-
Stoeck, K.1
Bodemer, M.2
Ciesielczyk, B.3
Meissner, B.4
Bartl, M.5
Heinemann, U.6
Zerr, I.7
-
117
-
-
3242745029
-
Role of interleukin-1 in prion disease-associated astrocyte activation
-
Schultz, J. et al. Role of interleukin-1 in prion disease-associated astrocyte activation. Am. J. Pathol. 165, 671-678 (2004). (Pubitemid 38971396)
-
(2004)
American Journal of Pathology
, vol.165
, Issue.2
, pp. 671-678
-
-
Schultz, J.1
Schwarz, A.2
Neidhold, S.3
Burwinkel, M.4
Riemer, C.5
Simon, D.6
Kopf, M.7
Otto, M.8
Baier, M.9
-
118
-
-
48849094991
-
Genes contributing to prion pathogenesis
-
Tamguney, G. et al. Genes contributing to prion pathogenesis. J. Gen. Virol. 89, 1777-1788 (2008).
-
(2008)
J. Gen. Virol.
, vol.89
, pp. 1777-1788
-
-
Tamguney, G.1
-
119
-
-
84872826163
-
Sod1 deficiency reduces incubation time in mouse models of prion disease
-
Akhtar, S. et al. Sod1 deficiency reduces incubation time in mouse models of prion disease. PLoS ONE 8, e54454 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
Akhtar, S.1
-
120
-
-
10044234319
-
Accelerated prion disease in the absence of interleukin-10
-
DOI 10.1128/JVI.78.24.13697-13707.2004
-
Thackray, A. M., McKenzie, A. N., Klein, M. A., Lauder, A. & Bujdoso, R. Accelerated prion disease in the absence of interleukin-10. J. Virol. 78, 13697-13707 (2004). (Pubitemid 39612768)
-
(2004)
Journal of Virology
, vol.78
, Issue.24
, pp. 13697-13707
-
-
Thackray, A.M.1
McKenzie, A.N.2
Klein, M.A.3
Lauder, A.4
Bujdoso, R.5
-
121
-
-
26944437441
-
MCP-1 and murine prion disease: Separation of early behavioural dysfunction from overt clinical disease
-
DOI 10.1016/j.nbd.2005.03.008, PII S0969996105000847
-
Felton, L. M. et al. MCP-1 and murine prion disease: separation of early behavioural dysfunction from overt clinical disease. Neurobiol. Dis. 20, 283-295 (2005). (Pubitemid 41476256)
-
(2005)
Neurobiology of Disease
, vol.20
, Issue.2
, pp. 283-295
-
-
Felton, L.M.1
Cunningham, C.2
Rankine, E.L.3
Waters, S.4
Boche, D.5
Perry, V.H.6
-
122
-
-
56049100019
-
Investigation of mcp1 as a quantitative trait gene for prion disease incubation time in mouse
-
O'Shea, M. et al. Investigation of mcp1 as a quantitative trait gene for prion disease incubation time in mouse. Genetics 180, 559-566 (2008).
-
(2008)
Genetics
, vol.180
, pp. 559-566
-
-
O'Shea, M.1
-
123
-
-
44349130889
-
Role of Erk1/2 activation in prion disease pathogenesis: Absence of CCR1 leads to increased Erk1/2 activation and accelerated disease progression
-
LaCasse, R. A., Striebel, J. F., Favara, C., Kercher, L. & Chesebro, B. Role of Erk1/2 activation in prion disease pathogenesis: absence of CCR1 leads to increased Erk1/2 activation and accelerated disease progression. J. Neuroimmunol. 196, 16-26 (2008).
-
(2008)
J. Neuroimmunol.
, vol.196
, pp. 16-26
-
-
Lacasse, R.A.1
Striebel, J.F.2
Favara, C.3
Kercher, L.4
Chesebro, B.5
-
124
-
-
0033779255
-
Identification of upregulated genes in scrapie-infected brain tissue
-
Riemer, C., Queck, I., Simon, D., Kurth, R. & Baier, M. Identification of upregulated genes in scrapie-infected brain tissue. J. Virol. 74, 10245-10248 (2000).
-
(2000)
J. Virol.
, vol.74
, pp. 10245-10248
-
-
Riemer, C.1
Queck, I.2
Simon, D.3
Kurth, R.4
Baier, M.5
-
125
-
-
57349181275
-
Accelerated prion replication in, but prolonged survival times of, prion-infected CXCR3-/-mice
-
Riemer, C. et al. Accelerated prion replication in, but prolonged survival times of, prion-infected CXCR3-/-mice. J. Virol. 82, 12464-12471 (2008).
-
(2008)
J. Virol.
, vol.82
, pp. 12464-12471
-
-
Riemer, C.1
-
126
-
-
0036838213
-
Microglia from Creutzfeldt-Jakob disease-infected brains are infectious and show specific mRNA activation profiles
-
DOI 10.1128/JVI.76.21.10905-10913.2002
-
Baker, C. A., Martin, D. & Manuelidis, L. Microglia from Creutzfeldt-Jakob disease-infected brains are infectious and show specific mRNA activation profiles. J. Virol. 76, 10905-10913 (2002). (Pubitemid 35176207)
-
(2002)
Journal of Virology
, vol.76
, Issue.21
, pp. 10905-10913
-
-
Baker, C.A.1
Martin, D.2
Manuelidis, L.3
-
127
-
-
77950188666
-
Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease
-
Fuhrmann, M. et al. Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease. Nature Neurosci. 13, 411-413 (2010).
-
(2010)
Nature Neurosci.
, vol.13
, pp. 411-413
-
-
Fuhrmann, M.1
-
128
-
-
0037085719
-
Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS
-
Hughes, P. M., Botham, M. S., Frentzel, S., Mir, A. & Perry, V. H. Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS. Glia 37, 314-327 (2002).
-
(2002)
Glia
, vol.37
, pp. 314-327
-
-
Hughes, P.M.1
Botham, M.S.2
Frentzel, S.3
Mir, A.4
Perry, V.H.5
-
129
-
-
84885948000
-
Abnormal activation of microglia accompanied with disrupted CX3CR1/CX3CL1 pathway in the brains of the hamsters infected with scrapie agent 263K
-
Xie, W. L. et al. Abnormal activation of microglia accompanied with disrupted CX3CR1/CX3CL1 pathway in the brains of the hamsters infected with scrapie agent 263K. J. Mol. Neurosci. 51, 919-932 (2013).
-
(2013)
J. Mol. Neurosci.
, vol.51
, pp. 919-932
-
-
Xie, W.L.1
-
130
-
-
0032721724
-
Expression of cytokine genes and increased nuclear factor-B activity in the brains of scrapie-infected mice
-
Kim, J. I. et al. Expression of cytokine genes and increased nuclear factor-B activity in the brains of scrapie-infected mice. Brain Res. Mol. Brain Res. 73, 17-27 (1999).
-
(1999)
Brain Res. Mol. Brain Res.
, vol.73
, pp. 17-27
-
-
Kim, J.I.1
-
131
-
-
34547868484
-
Alteration of NF-κB activity leads to mitochondrial apoptosis after infection with pathological prion protein
-
DOI 10.1111/j.1462-5822.2007.00950.x
-
Bourteele, S. et al. Alteration of NF-B activity leads to mitochondrial apoptosis after infection with pathological prion protein. Cell. Microbiol. 9, 2202-2217 (2007). (Pubitemid 47250292)
-
(2007)
Cellular Microbiology
, vol.9
, Issue.9
, pp. 2202-2217
-
-
Bourteele, S.1
Oesterle, K.2
Weinzierl, A.O.3
Paxian, S.4
Riemann, M.5
Schmid, R.M.6
Planz, O.7
-
132
-
-
45949106091
-
Prion propagation in mice lacking central nervous system NF-B signalling
-
Julius, C. et al. Prion propagation in mice lacking central nervous system NF-B signalling. J. Gen. Virol. 89, 1545-1550 (2008).
-
(2008)
J. Gen. Virol.
, vol.89
, pp. 1545-1550
-
-
Julius, C.1
-
133
-
-
70349668702
-
Repetitive immunization enhances the susceptibility of mice to peripherally administered prions
-
Bremer, J. et al. Repetitive immunization enhances the susceptibility of mice to peripherally administered prions. PLoS ONE 4, e7160 (2009).
-
(2009)
PLoS ONE
, vol.4
-
-
Bremer, J.1
-
134
-
-
84867911587
-
Genetic depletion of complement receptors CD21/35 prevents terminal prion disease in a mouse model of chronic wasting disease
-
Michel, B. et al. Genetic depletion of complement receptors CD21/35 prevents terminal prion disease in a mouse model of chronic wasting disease. J. Immunol. 189, 4520-4527 (2012).
-
(2012)
J. Immunol.
, vol.189
, pp. 4520-4527
-
-
Michel, B.1
-
135
-
-
0037143011
-
Postexposure prophylaxis against prion disease with a stimulator of innate immunity
-
DOI 10.1016/S0140-6736(02)09513-2
-
Sethi, S., Lipford, G., Wagner, H. & Kretzschmar, H. Postexposure prophylaxis against prion disease with a stimulator of innate immunity. Lancet 360, 229-230 (2002). (Pubitemid 34804655)
-
(2002)
Lancet
, vol.360
, Issue.9328
, pp. 229-230
-
-
Sethi, S.1
Lipford, G.2
Wagner, H.3
Kretzschmar, H.4
-
136
-
-
0842343142
-
Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration
-
DOI 10.1038/nm987
-
Heikenwalder, M. et al. Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration. Nature Med. 10, 187-192 (2004). (Pubitemid 38524890)
-
(2004)
Nature Medicine
, vol.10
, Issue.2
, pp. 187-192
-
-
Heikenwalder, M.1
Polymenidou, M.2
Junt, T.3
Sigurdson, C.4
Wagner, H.5
Akira, S.6
Zinkernagel, R.7
Aguzzi, A.8
-
137
-
-
0003279877
-
Immunoaffinity purification and neutralization of scrapie prion infectivity
-
USA
-
Gabizon, R., McKinley, M. P., Groth, D. & Prusiner, S. B. Immunoaffinity purification and neutralization of scrapie prion infectivity. Proc. Natl Acad. Sci. USA 85, 6617-6621 (1988).
-
(1988)
Proc. Natl Acad. Sci.
, vol.85
, pp. 6617-6621
-
-
Gabizon, R.1
McKinley, M.P.2
Groth, D.3
Prusiner, S.B.4
-
138
-
-
0035979274
-
Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody
-
DOI 10.1073/pnas.151242598
-
Enari, M., Flechsig, E. & Weissmann, C. Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody. Proc. Natl Acad. Sci. USA 98, 9295-9299 (2001). (Pubitemid 32743910)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.16
, pp. 9295-9299
-
-
Enari, M.1
Flechsig, E.2
Weissmann, C.3
-
139
-
-
0035899413
-
Antibodies inhibit prion propagation and clear cell cultures of prion infectivity
-
DOI 10.1038/35089090
-
Peretz, D. et al. Antibodies inhibit prion propagation and clear cell cultures of prion infectivity. Nature 412, 739-743 (2001). (Pubitemid 32771997)
-
(2001)
Nature
, vol.412
, Issue.6848
, pp. 739-743
-
-
Peretz, D.1
Williamson, R.A.2
Kaneko, K.3
Vergara, J.4
Leclerc, E.5
Schmitt-Ulms, G.6
Mehlhorn, I.R.7
Legname, G.8
Wormald, M.R.9
Rudd, P.M.10
Dwek, R.A.11
Burton, D.R.12
Prusiner, S.B.13
-
140
-
-
0033536163
-
Immunization with amyloid-β attenuates Alzheimer disease-like pathology in the PDAPP mouse
-
DOI 10.1038/22124
-
Schenk, D. et al. Immunization with amyloid-attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 400, 173-177 (1999). (Pubitemid 29327547)
-
(1999)
Nature
, vol.400
, Issue.6740
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guldo, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
141
-
-
0035812752
-
Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies
-
DOI 10.1126/science.1063093
-
Heppner, F. L. et al. Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies. Science 294, 178-182 (2001). (Pubitemid 32952973)
-
(2001)
Science
, vol.294
, Issue.5540
, pp. 178-182
-
-
Heppner, F.L.1
Musahl, C.2
Arrighi, I.3
Klein, M.A.4
Rulicke, T.5
Oesch, B.6
Zinkernagel, R.M.7
Kalinke, U.8
Aguzzi, A.9
-
142
-
-
0034856996
-
Modulation of proteinase-K resistant prion protein by prion peptide immunization
-
DOI 10.1002/1521-4141(200108)31:8<2338::AID-IMMU2338>3.0.CO;2-V
-
Souan, L. et al. Modulation of proteinase-K resistant prion protein by prion peptide immunization. Eur. J. Immunol. 31, 2338-2346 (2001). (Pubitemid 32785352)
-
(2001)
European Journal of Immunology
, vol.31
, Issue.8
, pp. 2338-2346
-
-
Souan, L.1
Tal, Y.2
Felling, Y.3
Cohen, I.R.4
Taraboulos, A.5
Mor, F.6
-
143
-
-
0036317750
-
Immunization delays the onset of prion disease in mice
-
Sigurdsson, E. M. et al. Immunization delays the onset of prion disease in mice. Am. J. Pathol. 161, 13-17 (2002). (Pubitemid 34760765)
-
(2002)
American Journal of Pathology
, vol.161
, Issue.1
, pp. 13-17
-
-
Sigurdsson, E.M.1
Brown, D.R.2
Daniels, M.3
Kascsak, R.J.4
Kascsak, R.5
Carp, R.6
Meeker, H.C.7
Frangione, B.8
Wisniewski, T.9
-
144
-
-
4444325310
-
Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection
-
DOI 10.1073/pnas.0404772101
-
Polymenidou, M. et al. Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection. Proc. Natl Acad. Sci. USA 101 (Suppl. 2), 14670-14676 (2004). (Pubitemid 39346741)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.SUPPL. 2
, pp. 14670-14676
-
-
Polymenidou, M.1
Heppner, F.L.2
Pellicioli, E.C.3
Urich, E.4
Miele, G.5
Braun, N.6
Wopfner, F.7
Schatzl, H.M.8
Becher, B.9
Aguzzi, A.10
-
145
-
-
84875030285
-
Immunization with recombinant prion protein leads to partial protection in a murine model of TSEs through a novel mechanism
-
Xanthopoulos, K. et al. Immunization with recombinant prion protein leads to partial protection in a murine model of TSEs through a novel mechanism. PLoS ONE 8, e59143 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
Xanthopoulos, K.1
-
146
-
-
33749483690
-
DNA vaccination can break immunological tolerance to PrP in wild-type mice and attenuates prion disease after intracerebral challenge
-
DOI 10.1128/JVI.01210-06
-
Fernandez-Borges, N. et al. DNA vaccination can break immunological tolerance to PrP in wild-type mice and attenuates prion disease after intracerebral challenge. J. Virol. 80, 9970-9976 (2006). (Pubitemid 44522591)
-
(2006)
Journal of Virology
, vol.80
, Issue.20
, pp. 9970-9976
-
-
Fernandez-Borges, N.1
Brun, A.2
Whitton, J.L.3
Parra, B.4
Diaz-San Segundo, F.5
Salguero, F.J.6
Torres, J.M.7
Rodriguez, F.8
-
147
-
-
0037422133
-
Monoclonal antibodies inhibit prion replication and delay the development of prion disease
-
DOI 10.1038/nature01457
-
White, A. R. et al. Monoclonal antibodies inhibit prion replication and delay the development of prion disease. Nature 422, 80-83 (2003). (Pubitemid 36323299)
-
(2003)
Nature
, vol.422
, Issue.6927
, pp. 80-83
-
-
White, A.R.1
Enever, P.2
Tayebi, M.3
Mushens, R.4
Linehan, J.5
Brandner, S.6
Anstee, D.7
Collinge, J.8
Hawke, S.9
-
148
-
-
0037461583
-
Anti-prion antibodies for prophylaxis following prion exposure in mice
-
DOI 10.1016/S0304-3940(02)01192-8
-
Sigurdsson, E. M. et al. Anti-prion antibodies for prophylaxis following prion exposure in mice. Neurosci. Lett. 336, 185-187 (2003). (Pubitemid 36044608)
-
(2003)
Neuroscience Letters
, vol.336
, Issue.3
, pp. 185-187
-
-
Sigurdsson, E.M.1
Sy, M.-S.2
Li, R.3
Scholtzova, H.4
Kascsak, R.J.5
Kascsak, R.6
Carp, R.7
Meeker, H.C.8
Frangione, B.9
Wisniewski, T.10
-
149
-
-
64449083691
-
Anti-PrP Mab 6D11 suppresses PrPSc replication in prion infected myeloid precursor line FDC-P1/22L and in the lymphoreticular system in vivo
-
Sadowski, M. J. et al. Anti-PrP Mab 6D11 suppresses PrPSc replication in prion infected myeloid precursor line FDC-P1/22L and in the lymphoreticular system in vivo. Neurobiol. Dis. 34, 267-278 (2009).
-
(2009)
Neurobiol. Dis.
, vol.34
, pp. 267-278
-
-
Sadowski, M.J.1
-
150
-
-
79955458680
-
Biological effects and use of PrPSc-and PrP-specific antibodies generated by immunization with purified full-length native mouse prions
-
Petsch, B. et al. Biological effects and use of PrPSc-and PrP-specific antibodies generated by immunization with purified full-length native mouse prions. J. Virol. 85, 4538-4546 (2011).
-
(2011)
J. Virol.
, vol.85
, pp. 4538-4546
-
-
Petsch, B.1
-
151
-
-
62449307945
-
Toxic effects of intracerebral PrP antibody administration during the course of BSE infection in mice
-
Lefebvre-Roque, M. et al. Toxic effects of intracerebral PrP antibody administration during the course of BSE infection in mice. Prion 1, 198-206 (2007).
-
(2007)
Prion
, vol.1
, pp. 198-206
-
-
Lefebvre-Roque, M.1
-
152
-
-
39849085645
-
CNS delivery of vectored prion-specific single-chain antibodies felays fisease onset
-
DOI 10.1038/sj.mt.6300387, PII 6300387
-
Wuertzer, C. A., Sullivan, M. A., Qiu, X. & Federoff, H. J. CNS delivery of vectored prion-specific single-chain antibodies delays disease onset. Mol. Ther. 16, 481-486 (2008). (Pubitemid 351314986)
-
(2008)
Molecular Therapy
, vol.16
, Issue.3
, pp. 481-486
-
-
Wuertzer, C.A.1
Sullivan, M.A.2
Qiu, X.3
Federoff, H.J.4
-
153
-
-
12144291519
-
Cross-Linking Cellular Prion Protein Triggers Neuronal Apoptosis in Vivo
-
DOI 10.1126/science.1094273
-
Solforosi, L. et al. Cross-linking cellular prion protein triggers neuronal apoptosis in vivo. Science 303, 1514-1516 (2004). (Pubitemid 38314420)
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1514-1516
-
-
Solforosi, L.1
Criado, J.R.2
McGavern, D.B.3
Wirz, S.4
Sanchez-Alavez, M.5
Sugama, S.6
DeGiorgio, L.A.7
Volpe, B.T.8
Wiseman, E.9
Abalos, G.10
Masliah, E.11
Gilden, D.12
Oldstone, M.B.13
Conti, B.14
Williamson, R.A.15
-
154
-
-
84883742582
-
The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein
-
Sonati, T. et al. The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein. Nature 501, 102-106 (2013).
-
(2013)
Nature
, vol.501
, pp. 102-106
-
-
Sonati, T.1
-
155
-
-
0032480316
-
Turning off follicular dendritic cells
-
Mackay, F. & Browning, J. L. Turning off follicular dendritic cells. Nature 395, 26-27 (1998).
-
(1998)
Nature
, vol.395
, pp. 26-27
-
-
MacKay, F.1
Browning, J.L.2
-
156
-
-
0037418828
-
Sc in vivo and antagonizes prion disease
-
DOI 10.1016/S0092-8674(03)00201-0
-
Meier, P. et al. Soluble dimeric prion protein binds PrPSc in vivo and antagonizes prion disease. Cell 113, 49-60 (2003). (Pubitemid 36411959)
-
(2003)
Cell
, vol.113
, Issue.1
, pp. 49-60
-
-
Meier, P.1
Genoud, N.2
Prinz, M.3
Maissen, M.4
Rulicke, T.5
Zurbriggen, A.6
Raeber, A.J.7
Aguzzi, A.8
-
157
-
-
0031942579
-
Mice with gene targetted prion protein alterations show that PRNP, Sinc and Prni are congruent
-
DOI 10.1038/ng0298-118
-
Moore, R. C. et al. Mice with gene targetted prion protein alterations show that Prnp, Sinc and Prni are congruent. Nature Genet. 18, 118-125 (1998). (Pubitemid 28082457)
-
(1998)
Nature Genetics
, vol.18
, Issue.2
, pp. 118-125
-
-
Moore, R.C.1
Hope, J.2
McBride, P.A.3
McConnell, I.4
Selfridge, J.5
Melton, D.W.6
Manson, J.C.7
-
158
-
-
0028535880
-
High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene
-
Bueler, H. et al. High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene. Mol. Med. 1, 19-30 (1994).
-
(1994)
Mol. Med.
, vol.1
, pp. 19-30
-
-
Bueler, H.1
-
159
-
-
13344282734
-
Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene
-
DOI 10.1038/380528a0
-
Sakaguchi, S. et al. Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene. Nature 380, 528-531 (1996). (Pubitemid 26110641)
-
(1996)
Nature
, vol.380
, Issue.6574
, pp. 528-531
-
-
Sakaguchi, S.1
Katamine, S.2
Nishida, N.3
Moriuchi, R.4
Shigematsu, K.5
Sugimoto, T.6
Nakatani, A.7
Kataoka, Y.8
Houtani, T.9
Shirabe, S.10
Okada, H.11
Hasegawa, S.12
Miyamoto, T.13
Noda, T.14
-
160
-
-
0033215478
-
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel
-
DOI 10.1006/jmbi.1999.3108
-
Moore, R. C. et al. Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel. J. Mol. Biol. 292, 797-817 (1999). (Pubitemid 29465475)
-
(1999)
Journal of Molecular Biology
, vol.292
, Issue.4
, pp. 797-817
-
-
Moore, R.C.1
Lee, I.Y.2
Silverman, G.L.3
Harrison, P.M.4
Strome, R.5
Heinrich, C.6
Karunaratne, A.7
Pasternak, S.H.8
Chishti, M.A.9
Liang, Y.10
Mastrangelo, P.11
Wang, K.12
Smit, A.F.A.13
Katamine, S.14
Carlson, G.A.15
Cohen, F.E.16
Prusiner, S.B.17
Melton, D.W.18
Tremblay, P.19
Hood, L.E.20
Westaway, D.21
more..
-
161
-
-
0242363656
-
Depleting Neuronal PrP in Prion Infection Prevents Disease and Reverses Spongiosis
-
DOI 10.1126/science.1090187
-
Mallucci, G. et al. Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis. Science 302, 871-874 (2003). (Pubitemid 37339628)
-
(2003)
Science
, vol.302
, Issue.5646
, pp. 871-874
-
-
Mallucci, G.1
Dickinson, A.2
Linehan, J.3
Klohn, P.-C.4
Brandner, S.5
Collinge, J.6
-
162
-
-
0025244011
-
Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication
-
Prusiner, S. B. et al. Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication. Cell 63, 673-686 (1990). (Pubitemid 120035041)
-
(1990)
Cell
, vol.63
, Issue.4
, pp. 673-686
-
-
Prusiner, S.B.1
Scott, M.2
Foster, D.3
Pan, K.-M.4
Groth, D.5
Mirenda, C.6
Torchia, M.7
Yang, S.-L.8
Serban, D.9
Carlson, G.A.10
Hoppe, P.C.11
Westaway, D.12
Dearmond, S.J.13
-
163
-
-
0029863648
-
Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie
-
Fischer, M. et al. Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. EMBO J. 15, 1255-1264 (1996). (Pubitemid 26093461)
-
(1996)
EMBO Journal
, vol.15
, Issue.6
, pp. 1255-1264
-
-
Fischer, M.1
Rulicke, T.2
Raeber, A.3
Sailer, A.4
Moser, M.5
Oesch, B.6
Brandner, S.7
Aguzzi, A.8
Weissmann, C.9
-
164
-
-
0024820814
-
Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques
-
DOI 10.1016/0092-8674(89)90608-9
-
Scott, M. et al. Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques. Cell 59, 847-857 (1989). (Pubitemid 20022375)
-
(1989)
Cell
, vol.59
, Issue.5
, pp. 847-857
-
-
Scott, M.1
Foster, D.2
Mirenda, C.3
Serban, D.4
Coufal, F.5
Walchli, M.6
Torchia, M.7
Groth, D.8
Carlson, G.9
DeArmond, S.J.10
Westaway, D.11
Prusiner, S.B.12
-
165
-
-
0028882424
-
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
-
Telling, G. C. et al. Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell 83, 79-90 (1995).
-
(1995)
Cell
, vol.83
, pp. 79-90
-
-
Telling, G.C.1
-
166
-
-
0001552281
-
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions
-
DOI 10.1016/S0092-8674(00)81572-X
-
Shmerling, D. et al. Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions. Cell 93, 203-214 (1998). (Pubitemid 28180854)
-
(1998)
Cell
, vol.93
, Issue.2
, pp. 203-214
-
-
Shmerling, D.1
Hegyi, I.2
Fischer, M.3
Blattler, T.4
Brandner, S.5
Gotz, J.6
Rulicke, T.7
Flechsig, E.8
Cozzio, A.9
Von Mering, C.10
Hangartner, C.11
Aguzzi, A.12
Weissmann, C.13
-
167
-
-
58549102983
-
De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis
-
USA
-
Sigurdson, C. J. et al. De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis. Proc. Natl Acad. Sci. USA 106, 304-309 (2009).
-
(2009)
Proc. Natl Acad. Sci.
, vol.106
, pp. 304-309
-
-
Sigurdson, C.J.1
-
168
-
-
61349201380
-
Cellular prion protein mediates impairment of synaptic plasticity by amyloid-oligomers
-
Lauren, J., Gimbel, D. A., Nygaard, H. B., Gilbert, J. W. & Strittmatter, S. M. Cellular prion protein mediates impairment of synaptic plasticity by amyloid-oligomers. Nature 457, 1128-1132 (2009).
-
(2009)
Nature
, vol.457
, pp. 1128-1132
-
-
Lauren, J.1
Gimbel, D.A.2
Nygaard, H.B.3
Gilbert, J.W.4
Strittmatter, S.M.5
-
169
-
-
84869992747
-
The complex PrPC-Fyn couples human oligomeric A with pathological tau changes in Alzheimer's disease
-
Larson, M. et al. The complex PrPC-Fyn couples human oligomeric A with pathological tau changes in Alzheimer's disease. J. Neurosci. 32, 16857-16871 (2012).
-
(2012)
J. Neurosci.
, vol.32
, pp. 16857-16871
-
-
Larson, M.1
-
170
-
-
77951876319
-
Memory impairment in transgenic Alzheimer mice requires cellular prion protein
-
Gimbel, D. A. et al. Memory impairment in transgenic Alzheimer mice requires cellular prion protein. J. Neurosci. 30, 6367-6374 (2010).
-
(2010)
J. Neurosci.
, vol.30
, pp. 6367-6374
-
-
Gimbel, D.A.1
-
171
-
-
84866065959
-
Alzheimer amyloid-oligomer bound to postsynaptic prion protein activates Fyn to impair neurons
-
Um, J. W. et al. Alzheimer amyloid-oligomer bound to postsynaptic prion protein activates Fyn to impair neurons. Nature Neurosci. 15, 1227-1235 (2012).
-
(2012)
Nature Neurosci.
, vol.15
, pp. 1227-1235
-
-
Um, J.W.1
-
172
-
-
76649093635
-
Synthetic amyloid-oligomers impair long-term memory independently of cellular prion protein
-
USA
-
Balducci, C. et al. Synthetic amyloid-oligomers impair long-term memory independently of cellular prion protein. Proc. Natl Acad. Sci. USA 107, 2295-2300 (2010).
-
(2010)
Proc. Natl Acad. Sci.
, vol.107
, pp. 2295-2300
-
-
Balducci, C.1
-
173
-
-
77956165325
-
Prion protein and A-related synaptic toxicity impairment
-
Calella, A. M. et al. Prion protein and A-related synaptic toxicity impairment. EMBO Mol. Med. 2, 306-314 (2010).
-
(2010)
EMBO Mol. Med.
, vol.2
, pp. 306-314
-
-
Calella, A.M.1
-
174
-
-
77955617917
-
The prion protein as a receptor for amyloid
-
Kessels, H. W., Nguyen, L. N., Nabavi, S. & Malinow, R. The prion protein as a receptor for amyloid-. Nature 466, E3-E4 (2010).
-
(2010)
Nature
, vol.466
-
-
Kessels, H.W.1
Nguyen, L.N.2
Nabavi, S.3
Malinow, R.4
-
175
-
-
77957375690
-
Somatic mosaicism in a case of apparently sporadic Creutzfeldt-Jakob disease carrying a de novo D178N mutation in the PRNP gene
-
Alzualde, A. et al. Somatic mosaicism in a case of apparently sporadic Creutzfeldt-Jakob disease carrying a de novo D178N mutation in the PRNP gene. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B, 1283-1291 (2010).
-
(2010)
Am. J. Med. Genet. B Neuropsychiatr. Genet.
, vol.153 B
, pp. 1283-1291
-
-
Alzualde, A.1
-
176
-
-
0141782730
-
Immunisation with a synthetic prion protein-derived peptide prolongs survival times of mice orally exposed to the scrapie agent
-
DOI 10.1016/S0304-3940(03)00907-8
-
Schwarz, A. et al. Immunisation with a synthetic prion protein-derived peptide prolongs survival times of mice orally exposed to the scrapie agent. Neurosci. Lett. 350, 187-189 (2003). (Pubitemid 37205197)
-
(2003)
Neuroscience Letters
, vol.350
, Issue.3
, pp. 187-189
-
-
Schwarz, A.1
Kratke, O.2
Burwinkel, M.3
Riemer, C.4
Schultz, J.5
Henklein, P.6
Bamme, T.7
Baier, M.8
-
177
-
-
43049165807
-
High titers of mucosal and systemic anti-PrP antibodies abrogate oral prion infection in mucosal-vaccinated mice
-
Goni, F. et al. High titers of mucosal and systemic anti-PrP antibodies abrogate oral prion infection in mucosal-vaccinated mice. Neuroscience 153, 679-686 (2008).
-
(2008)
Neuroscience
, vol.153
, pp. 679-686
-
-
Goni, F.1
-
178
-
-
32344443856
-
Intranasal immunization of Balb/c mice against prion protein attenuates orally acquired transmissible spongiform encephalopathy
-
DOI 10.1016/j.vaccine.2005.12.051, PII S0264410X06000132
-
Bade, S., Baier, M., Boetel, T. & Frey, A. Intranasal immunization of Balb/c mice against prion protein attenuates orally acquired transmissible spongiform encephalopathy. Vaccine 24, 1242-1253 (2006). (Pubitemid 43222031)
-
(2006)
Vaccine
, vol.24
, Issue.9
, pp. 1242-1253
-
-
Bade, S.1
Baier, M.2
Boetel, T.3
Frey, A.4
-
179
-
-
36348985473
-
Anti-prion activity generated by a novel vaccine formulation
-
DOI 10.1016/j.neulet.2007.10.015, PII S0304394007011007
-
Pilon, J. et al. Anti-prion activity generated by a novel vaccine formulation. Neurosci. Lett. 429, 161-164 (2007). (Pubitemid 350161127)
-
(2007)
Neuroscience Letters
, vol.429
, Issue.2-3
, pp. 161-164
-
-
Pilon, J.1
Loiacono, C.2
Okeson, D.3
Lund, S.4
Vercauteren, K.5
Rhyan, J.6
Miller, L.7
-
180
-
-
33845574428
-
Immunization with recombinant bovine but not mouse prion protein delays the onset of disease in mice inoculated with a mouse-adapted prion
-
DOI 10.1016/j.vaccine.2006.09.078, PII S0264410X06010802
-
Ishibashi, D. et al. Immunization with recombinant bovine but not mouse prion protein delays the onset of disease in mice inoculated with a mouse-adapted prion. Vaccine 25, 985-992 (2007). (Pubitemid 44937461)
-
(2007)
Vaccine
, vol.25
, Issue.6
, pp. 985-992
-
-
Ishibashi, D.1
Yamanaka, H.2
Yamaguchi, N.3
Yoshikawa, D.4
Nakamura, R.5
Okimura, N.6
Yamaguchi, Y.7
Shigematsu, K.8
Katamine, S.9
Sakaguchi, S.10
-
181
-
-
34447630431
-
Immunisation strategies against prion diseases: Prime-boost immunisation with a PrP DNA vaccine containing foreign helper T-cell epitopes does not prevent mouse scrapie
-
DOI 10.1016/j.vetmic.2007.03.032, PII S0378113507001642, Recent Progress in Prion Research Scientific Advances Reported at the Concluding Meeting of the German TSE Research Platform
-
Nitschke, C. et al. Immunisation strategies against prion diseases: prime-boost immunisation with a PrP DNA vaccine containing foreign helper T-cell epitopes does not prevent mouse scrapie. Vet. Microbiol. 123, 367-376 (2007). (Pubitemid 47088864)
-
(2007)
Veterinary Microbiology
, vol.123
, Issue.4
, pp. 367-376
-
-
Nitschke, C.1
Flechsig, E.2
Van Den Brandt, J.3
Lindner, N.4
Luhrs, T.5
Dittmer, U.6
Klein, M.A.7
-
182
-
-
47949097564
-
Contribution of antibody and T cell-specific responses to the progression of 139A-scrapie in C57BL/6 mice immunized with prion protein peptides
-
Sacquin, A., Bergot, A. S., Aucouturier, P. & Bruley-Rosset, M. Contribution of antibody and T cell-specific responses to the progression of 139A-scrapie in C57BL/6 mice immunized with prion protein peptides. J. Immunol. 181, 768-775 (2008).
-
(2008)
J. Immunol.
, vol.181
, pp. 768-775
-
-
Sacquin, A.1
Bergot, A.S.2
Aucouturier, P.3
Bruley-Rosset, M.4
-
183
-
-
63449116222
-
Unswitched immunoglobulin M response prolongs mouse survival in prion disease
-
Tayebi, M., Collinge, J. & Hawke, S. Unswitched immunoglobulin M response prolongs mouse survival in prion disease. J. Gen. Virol. 90, 777-782 (2009).
-
(2009)
J. Gen. Virol.
, vol.90
, pp. 777-782
-
-
Tayebi, M.1
Collinge, J.2
Hawke, S.3
-
184
-
-
63349097762
-
Dendritic cell-mediated-immunization with xenogenic PrP and adenoviral vectors breaks tolerance and prolongs mice survival against experimental scrapie
-
Rosset, M. B. et al. Dendritic cell-mediated-immunization with xenogenic PrP and adenoviral vectors breaks tolerance and prolongs mice survival against experimental scrapie. PLoS ONE 4, e4917 (2009).
-
(2009)
PLoS ONE
, vol.4
-
-
Rosset, M.B.1
-
185
-
-
76849115603
-
Mouse vaccination with dendritic cells loaded with prion protein peptides overcomes tolerance and delays scrapie
-
Bachy, V. et al. Mouse vaccination with dendritic cells loaded with prion protein peptides overcomes tolerance and delays scrapie. J. Gen. Virol. 91, 809-820 (2010).
-
(2010)
J. Gen. Virol.
, vol.91
, pp. 809-820
-
-
Bachy, V.1
-
186
-
-
80855131605
-
Antigenic mimicry-mediated anti-prion effects induced by bacterial enzyme succinylarginine dihydrolase in mice
-
Ishibashi, D. et al. Antigenic mimicry-mediated anti-prion effects induced by bacterial enzyme succinylarginine dihydrolase in mice. Vaccine 29, 9321-9328 (2011).
-
(2011)
Vaccine
, vol.29
, pp. 9321-9328
-
-
Ishibashi, D.1
-
187
-
-
84873728561
-
Immunotherapy in prion disease
-
Roettger, Y. et al. Immunotherapy in prion disease. Nature Rev. Neurol. 9, 98-105 (2013).
-
(2013)
Nature Rev. Neurol.
, vol.9
, pp. 98-105
-
-
Roettger, Y.1
|