Follicular dendritic cell-specific prion protein (PrP c) expression alone is sufficient to sustain prion infection in the spleen

PLoS Pathogens

Volumn 7, Issue 12, 2011, Pages

  McCulloch, Laura ^a   Brown, Karen L ^a   Bradford, Barry M ^a   Hopkins, John ^a   Bailey, Mick ^b   Rajewsky, Klaus ^c   Manson, Jean C ^a   Mabbott, Neil A ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; FOLLICULAR DENDRITIC CELL; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PRION; PRION DISEASE; PROTEIN EXPRESSION; SPLEEN DISEASE; TRANSGENIC MOUSE; VIRUS REPLICATION; ANIMAL; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE MUTANT; PATHOGENICITY; PATHOLOGY; SPLEEN;

MUS MUSCULUS;

ANIMALS; DENDRITIC CELLS, FOLLICULAR; GENE EXPRESSION REGULATION; MICE; MICE, KNOCKOUT; PRION DISEASES; PRPC PROTEINS; SPLEEN;

EID: 84855282475     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002402     Document Type: Article

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