Anti-PrP Mab 6D11 suppresses PrPSc replication in prion infected myeloid precursor line FDC-P1/22L and in the lymphoreticular system in vivo

Neurobiology of Disease

Volumn 34, Issue 2, 2009, Pages 267-278

  Sadowski, Martin J ^a   Pankiewicz, Joanna ^a   Prelli, Frances ^a   Scholtzova, Henrieta ^a   Spinner, Daryl S ^b   Kascsak, Regina B ^b   Kascsak, Richard J ^b   Wisniewski, Thomas ^a,b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Creutzfeldt Jakob disease; Monoclonal antibodies; Neuroinvasion; Prion; Scrapie; Treatment

Indexed keywords

IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 6D11; PRION PROTEIN; PRION PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LINE; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; FEMALE; HUMAN; HUMAN TISSUE; IN VIVO STUDY; INCUBATION TIME; INFECTION PREVENTION; MOUSE; MYELOID PROGENITOR CELL; NEUROPATHOLOGY; NONHUMAN; PASSIVE IMMUNIZATION; PRION DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; RETICULOENDOTHELIAL SYSTEM; SCRAPIE AGENT; SINGLE DRUG DOSE; TREATMENT OUTCOME;

ANIMALS; ANTIBODIES, MONOCLONAL; BLOOD-BRAIN BARRIER; BRAIN; CELL LINE; DOWN-REGULATION; FEMALE; HUMANS; IMMUNIZATION, PASSIVE; LYMPHATIC SYSTEM; MICE; MYELOID CELLS; MYELOID PROGENITOR CELLS; PRION DISEASES; PROTEIN CONFORMATION; PRPSC PROTEINS; SCRAPIE; TREATMENT OUTCOME;

EID: 64449083691     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2009.01.013     Document Type: Article

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