Requirement of cellular prion protein for intestinal barrier function and mislocalization in patients with inflammatory bowel disease

Gastroenterology

Volumn 143, Issue 1, 2012, Pages

  Petit, Constance S V ^a,b   Barreau, Frédérick ^c   Besnier, Laura ^a,b   Gandille, Pierre ^a,b   Riveau, Béatrice ^a,b   Chateau, Danielle ^a,b   Roy, Maryline ^c   Berrebi, Dominique ^b   Svrcek, Magali ^d,e,f,g   Cardot, Philippe ^a,b   Rousset, Monique ^a,b   Clair, Caroline ^a,b   Thenet, Sophie ^a,b,h  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c INSERM   (France)

^d ARMAND TROUSSEAU HOSPITAL   (France)

^e SORBONNE UNIVERSITÉ   (France)

^f CENTRE DE RECHERCHE SAINT ANTOINE   (France)

^g HÔPITAL SAINT ANTOINE   (France)

^h PSL RESEARCH UNIVERSITY   (France)

Author keywords

Cell Cell Adhesion; Inflammation; Mouse Model; Tight Junction

Indexed keywords

CLAUDIN 4; DESMOPLAKIN; DEXTRAN SULFATE; OCCLUDIN; PLAKOGLOBIN; PRION PROTEIN; PROTEIN; PROTEIN ZO1; SHORT HAIRPIN RNA; TRICELLULIN; UNCLASSIFIED DRUG; UVOMORULIN;

ADULT; ANIMAL TISSUE; ARTICLE; CELL JUNCTION; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; COLON MUCOSA; ENTERITIS; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE; INTESTINE CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

EID: 84862775532     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2012.03.029     Document Type: Article

References (42)

1. L. Westergard, H.M. Christensen, D.A. Harris The cellular prion protein (PrP(C)): its physiological function and role in disease Biochim Biophys Acta 1772 2007 629 644
2. D. Sarnataro, S. Paladino, V. Campana PrPC is sorted to the basolateral membrane of epithelial cells independently of its association with rafts Traffic 3 2002 810 821
3. E. Morel, S. Fouquet, D. Chateau The cellular prion protein PrPc is expressed in human enterocytes in cell-cell junctional domains J Biol Chem 279 2004 1499 1505
4. A. Mange, O. Milhavet, D. Umlauf PrP-dependent cell adhesion in N2a neuroblastoma cells FEBS Lett 514 2002 159 162
5. E. Malaga-Trillo, G.P. Solis, Y. Schrock Regulation of embryonic cell adhesion by the prion protein PLoS Biol 7 2009 e55
6. P. Viegas, N. Chaverot, H. Enslen Junctional expression of the prion protein PrPC by brain endothelial cells: a role in trans-endothelial migration of human monocytes J Cell Sci 119 2006 4634 4643
7. E. Morel, S. Fouquet, C. Strup-Perrot The cellular prion protein PrP(c) is involved in the proliferation of epithelial cells and in the distribution of junction-associated proteins PLoS One 3 2008 e3000
8. J.R. Turner Intestinal mucosal barrier function in health and disease Nat Rev Immunol 9 2009 799 809
9. M.L. Hermiston, J.I. Gordon In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death J Cell Biol 129 1995 489 506
10. S. Fouquet, V.H. Lugo-Martinez, A.M. Faussat Early loss of E-cadherin from cell-cell contacts is involved in the onset of Anoikis in enterocytes J Biol Chem 279 2004 43061 43069
11. G. Peignon, S. Thenet, C. Schreider E-cadherin-dependent transcriptional control of apolipoprotein A-IV gene expression in intestinal epithelial cells: a role for the hepatic nuclear factor 4 J Biol Chem 281 2006 3560 3568
12. A. Tamura, Y. Kitano, M. Hata Megaintestine in claudin-15-deficient mice Gastroenterology 134 2008 523 534
13. M.G. Laukoetter, P. Nava, A. Nusrat Role of the intestinal barrier in inflammatory bowel disease World J Gastroenterol 14 2008 401 407
14. N. Oshitani, K. Watanabe, S. Nakamura Dislocation of tight junction proteins without F-actin disruption in inactive Crohn's disease Int J Mol Med 15 2005 407 410
15. S.A. Blair, S.V. Kane, D.R. Clayburgh Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease Lab Invest 86 2006 191 201
16. S. Zeissig, N. Burgel, D. Gunzel Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease Gut 56 2007 61 72
17. M.L. Hermiston, J.I. Gordon Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin Science 270 1995 1203 1207
18. M.G. Laukoetter, P. Nava, W.Y. Lee JAM-A regulates permeability and inflammation in the intestine in vivo J Exp Med 204 2007 3067 3076
19. S. Vetrano, M. Rescigno, M. Rosaria Cera Unique role of junctional adhesion molecule-a in maintaining mucosal homeostasis in inflammatory bowel disease Gastroenterology 135 2008 173 184
20. F. Barreau, U. Meinzer, F. Chareyre CARD15/NOD2 is required for Peyer's patches homeostasis in mice PLoS One 2 2007 e523
21. A.L. Cattin, J. Le Beyec, F. Barreau Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium Mol Cell Biol 29 2009 6294 6308
22. H.S. Cooper, S.N. Murthy, R.S. Shah Clinicopathologic study of dextran sulfate sodium experimental murine colitis Lab Invest 69 1993 238 249
23. J.M. Anderson, C.M. Van Itallie Physiology and function of the tight junction Cold Spring Harb Perspect Biol 1 2009 a002584
24. A.D. Steele, S. Lindquist, A. Aguzzi The prion protein knockout mouse: a phenotype under challenge Prion 1 2007 83 93
25. F. Wang, W.V. Graham, Y. Wang Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression Am J Pathol 166 2005 409 419
26. N. Gassler, C. Rohr, A. Schneider Inflammatory bowel disease is associated with changes of enterocytic junctions Am J Physiol Gastrointest Liver Physiol 281 2001 G216 G228
27. W.G. Smalley-Freed, A. Efimov, P.E. Burnett p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice J Clin Invest 120 2010 1824 1835
28. Schlegel N, Meir M, Heupel WM, et al. Desmoglein 2-mediated adhesion is required for intestinal epithelial barrier integrity. Am J Physiol Gastrointest Liver Physiol;298:G774-G783.
29. B. Gumbiner, B. Stevenson, A. Grimaldi The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex J Cell Biol 107 1988 1575 1587
30. M.C. Frame, V.J. Fincham, N.O. Carragher v-Src's hold over actin and cell adhesions Nat Rev Mol Cell Biol 3 2002 233 245
31. G. Kale, A.P. Naren, P. Sheth Tyrosine phosphorylation of occludin attenuates its interactions with ZO-1, ZO-2, and ZO-3 Biochem Biophys Res Commun 302 2003 324 329
32. P.P. Lie, C.Y. Cheng, D.D. Mruk Crosstalk between desmoglein-2/ desmocollin-2/Src kinase and coxsackie and adenovirus receptor/ZO-1 protein complexes, regulates blood-testis barrier dynamics Int J Biochem Cell Biol 42 2010 975 986
33. L. Su, L. Shen, D.R. Clayburgh Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis Gastroenterology 136 2009 551 563
34. R. Linden, V.R. Martins, M.A. Prado Physiology of the prion protein Physiol Rev 88 2008 673 728
35. R.J. Ingram, J.D. Isaacs, G. Kaur A role of cellular prion protein in programming T-cell cytokine responses in disease FASEB J 23 2009 1672 1684
36. T. Sklyarova, S. Bonne, P. D'Hooge Plakophilin-3-deficient mice develop hair coat abnormalities and are prone to cutaneous inflammation J Invest Dermatol 128 2008 1375 1385
37. E.A. Leclerc, A. Huchenq, N.R. Mattiuzzo Corneodesmosin gene ablation induces lethal skin-barrier disruption and hair-follicle degeneration related to desmosome dysfunction J Cell Sci 122 2009 2699 2709
38. K.J. Green, S. Getsios, S. Troyanovsky Intercellular junction assembly, dynamics, and homeostasis Cold Spring Harb Perspect Biol 2 2010 a000125
39. H.S. Cooper, S.N. Murthy, R.S. Shah Clinicopathologic study of dextran sulfate sodium experimental murine colitis Lab Invest 69 1993 238 249
40. E. Morel, S. Fouquet, C. Strup-Perrot The cellular prion protein PrP(c) is involved in the proliferation of epithelial cells and in the distribution of junction-associated proteins PLoS ONE 3 2008 e3000
41. V.H. Lugo-Martinez, C.S. Petit, S. Fouquet Epidermal growth factor receptor is involved in enterocyte anoikis through the dismantling of E-cadherin-mediated junctions Am J Physiol Gastrointest Liver Physiol 296 2009 G235 G244
42. H. Hauser, K. Howell, R.M. Dawson Rabbit small intestinal brush border membrane preparation and lipid composition Biochim Biophys Acta 602 1980 567 577