Transepithelial prion transport by M cells

Nature Medicine

Volumn 7, Issue 9, 2001, Pages 976-977

  Heppner, Frank L ^a   Klein, Michael A ^a   Prinz, Marco ^a   Aguzzi, Adriano ^a   Christ, Andreas D ^b   Fried, Michael ^b   Kraenhenbuhl, Jean Pierre ^c  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR6; PRION PROTEIN; UNCLASSIFIED DRUG;

BOVINE SPONGIFORM ENCEPHALOPATHY; CELL ACTIVITY; CELL DIFFERENTIATION; CELL STRAIN CACO 2; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; FLUORESCENCE; HUMAN; HUMAN CELL; IMMUNE SYSTEM; LETTER; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAJI CELL; TEMPERATURE DEPENDENCE; TRANSCYTOSIS;

ANIMALS; BIOLOGICAL TRANSPORT; CELL DIFFERENTIATION; CELLS, CULTURED; CHEMOKINES, CC; COCULTURE TECHNIQUES; EPITHELIAL CELLS; HUMANS; MACROPHAGE INFLAMMATORY PROTEINS; MICE; MICE, TRANSGENIC; MICROSPHERES; PRIONS; RECEPTORS, CHEMOKINE;

EID: 0034797467     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0901-976     Document Type: Letter

References (8)

1. A new variant of Creutzfeldt-Jakob disease in the UK
2. Epithelial M cells: Gateways for mucosal infection and immunization
3. Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteria
4. Flagellin stimulation of intestinal epithelial cells triggers CCL20-mediated migration of dendritic cells
5. Mice devoid of PrP are resistant to scrapie
6. Prion protein (PrP) with aminoproximal deletions restoring susceptibility of PrP knockout mice to scrapie
7. Pathogenesis of prion diseases: A progress report
8. Normal host prion protein necessary for scrapie-induced neurotoxicity