Intranasal immunization of Balb/c mice against prion protein attenuates orally acquired transmissible spongiform encephalopathy

Vaccine

Volumn 24, Issue 9, 2006, Pages 1242-1253

  Bade, Steffen ^a   Baier, Michael ^b   Boetel, Thurid ^a   Frey, Andreas ^a  

^a RESEARCH CENTER BORSTEL   (Germany)

^b ROBERT KOCH INSTITUTE   (Germany)

Author keywords

Intranasal immunization; Prions; Secretory IgA

Indexed keywords

APROTININ; CHOLERA TOXIN; PRION PROTEIN; RECOMBINANT PRION PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN SPONGIOSIS; CONTROLLED STUDY; DISEASE TRANSMISSION; DRUG FORMULATION; FEMALE; IMMUNE RESPONSE; IMMUNIZATION; INTESTINE LAVAGE; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; SURVIVAL RATE; VACCINE FAILURE;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, INTRANASAL; ANIMALS; APROTININ; CHOLERA TOXIN; DISEASE MODELS, ANIMAL; FECES; FEMALE; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A, SECRETORY; IMMUNOGLOBULIN G; MICE; MICE, INBRED BALB C; PEPTIDE FRAGMENTS; PRION DISEASES; PRIONS; SERINE PROTEINASE INHIBITORS; URINE; VACCINES, SYNTHETIC;

EID: 32344443856     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2005.12.051     Document Type: Article

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