-
1
-
-
0242300624
-
Games played by rogue proteins in prion disorders and Alzheimer's disease
-
Aguzzi, A. & Haass, C. Games played by rogue proteins in prion disorders and Alzheimer's disease. Science 302, 814-818 (2003).
-
(2003)
Science
, vol.302
, pp. 814-818
-
-
Aguzzi, A.1
Haass, C.2
-
3
-
-
0023669586
-
A novel progressive spongiform encephalopathy in cattle
-
Wells, G. A. et al. A novel progressive spongiform encephalopathy in cattle. Vet. Rec. 121, 419-420 (1987).
-
(1987)
Vet. Rec.
, vol.121
, pp. 419-420
-
-
Wells, G.A.1
-
4
-
-
0030856847
-
Bovine spongiform encephalopathy and early onset variant Creutzfeldt-Jakob disease
-
Weissmann, C. & Aguzzi, A. Bovine spongiform encephalopathy and early onset variant Creutzfeldt-Jakob disease. Curr. Opin. Neurobiol. 7, 695-700 (1997).
-
(1997)
Curr. Opin. Neurobiol.
, vol.7
, pp. 695-700
-
-
Weissmann, C.1
Aguzzi, A.2
-
5
-
-
0033629344
-
Inactivation of transmissible degenerative encephalopathy agents: A review
-
Taylor, D. M. Inactivation of transmissible degenerative encephalopathy agents: a review. Vet. J. 159, 10-17 (2000).
-
(2000)
Vet. J.
, vol.159
, pp. 10-17
-
-
Taylor, D.M.1
-
6
-
-
0030903469
-
Neuro-immune connection in spread of prions in the body?
-
Aguzzi, A. Neuro-immune connection in spread of prions in the body? Lancet 349, 742-743 (1997).
-
(1997)
Lancet
, vol.349
, pp. 742-743
-
-
Aguzzi, A.1
-
7
-
-
0035899460
-
A route for prion neuroinvasion
-
Nicotera, P. A route for prion neuroinvasion. Neuron 31, 345-348 (2001).
-
(2001)
Neuron
, vol.31
, pp. 345-348
-
-
Nicotera, P.1
-
9
-
-
0023663071
-
Scrapie prion protein contains a phosphatidylinositol glycolipid
-
Stahl, N., Borchett, D. R., Hsiao, K. & Prusiner, S. B. Scrapie prion protein contains a phosphatidylinositol glycolipid. Cell 51, 229-240 (1987).
-
(1987)
Cell
, vol.51
, pp. 229-240
-
-
Stahl, N.1
Borchett, D.R.2
Hsiao, K.3
Prusiner, S.B.4
-
10
-
-
0034904789
-
Cellular prion protein status in sheep: Tissue-specific biochemical signatures
-
Moudjou, M., Frobert, Y., Grassi, J. & La Bonnardiere, C. Cellular prion protein status in sheep: tissue-specific biochemical signatures. J. Gen. Virol. 82, 2017-2024 (2001).
-
(2001)
J. Gen. Virol.
, vol.82
, pp. 2017-2024
-
-
Moudjou, M.1
Frobert, Y.2
Grassi, J.3
La Bonnardiere, C.4
-
11
-
-
0037242707
-
Embryonic activation and developmental expression of the murine prion protein gene
-
Miele, G. et al. Embryonic activation and developmental expression of the murine prion protein gene. Gene Expr. 11, 1-12 (2003).
-
(2003)
Gene Expr.
, vol.11
, pp. 1-12
-
-
Miele, G.1
-
12
-
-
0026600865
-
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
-
Büeler, H. R. et al. Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature 356, 577-582 (1992).
-
(1992)
Nature
, vol.356
, pp. 577-582
-
-
Büeler, H.R.1
-
13
-
-
0027997387
-
Prion protein is necessary for normal synaptic function
-
Collinge, J. et al. Prion protein is necessary for normal synaptic function. Nature 370, 295-297 (1994).
-
(1994)
Nature
, vol.370
, pp. 295-297
-
-
Collinge, J.1
-
14
-
-
15844421385
-
Altered arcadian activity rhythms and sleep in mice devoid of prion protein
-
Tobler, I. et al. Altered arcadian activity rhythms and sleep in mice devoid of prion protein. Nature 380, 639-642 (1996).
-
(1996)
Nature
, vol.380
, pp. 639-642
-
-
Tobler, I.1
-
15
-
-
0032562558
-
Prion protein structural features indicate possible relations to signal peptidases
-
Glockshuber, R. et al. Prion protein structural features indicate possible relations to signal peptidases. FEBS Lett. 426, 291-296 (1998).
-
(1998)
FEBS Lett.
, vol.426
, pp. 291-296
-
-
Glockshuber, R.1
-
16
-
-
0031194455
-
Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity
-
Brown, D. R., Schulz-Schaeffer, W. J., Schmidt, B. & Kretzschmar, H. A. Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity. Exp. Neurol. 146, 104-112 (1997).
-
(1997)
Exp. Neurol.
, vol.146
, pp. 104-112
-
-
Brown, D.R.1
Schulz-Schaeffer, W.J.2
Schmidt, B.3
Kretzschmar, H.A.4
-
17
-
-
0033571055
-
Normal prion protein has an activity like that of superoxide dismutase
-
Brown, D. R. et al. Normal prion protein has an activity like that of superoxide dismutase. Biochem. J. 344, 1-5 (1999).
-
(1999)
Biochem. J.
, vol.344
, pp. 1-5
-
-
Brown, D.R.1
-
18
-
-
0041664024
-
Impairment of Superoxide dismutase actuation by N-terminally truncated prion protein (PrP) in PrP-deficient neuronal cell line
-
Sakudo, A. et al. Impairment of Superoxide dismutase actuation by N-terminally truncated prion protein (PrP) in PrP-deficient neuronal cell line. Biochem. Biophys. Res. Commun. 308, 660-667 (2003).
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.308
, pp. 660-667
-
-
Sakudo, A.1
-
19
-
-
0034678023
-
Brain copper content and cuproenzyme activity do not vary with prion protein expression level
-
Waggoner, D. J. et al. Brain copper content and cuproenzyme activity do not vary with prion protein expression level. J. Biol. Chem. 275, 7455-7458 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 7455-7458
-
-
Waggoner, D.J.1
-
20
-
-
0141717118
-
No Superoxide dismutase activity of cellular prion protein in vivo
-
Hutter, G., Heppner, F. L. & Aguzzi, A. No Superoxide dismutase activity of cellular prion protein in vivo. Biol. Chem. 384, 1279-1285 (2003).
-
(2003)
Biol. Chem.
, vol.384
, pp. 1279-1285
-
-
Hutter, G.1
Heppner, F.L.2
Aguzzi, A.3
-
21
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
Prusiner, S. B. Novel proteinaceous infectious particles cause scrapie. Science 216, 136-144 (1982). Classic enunciation of the protein-only hypothesis of prion disease by Stanley Prusiner.
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
22
-
-
0031720905
-
Sc molecules with different conformations
-
Sc molecules with different conformations Nature Med. 4, 1157-1165 (1998).
-
(1998)
Nature Med.
, vol.4
, pp. 1157-1165
-
-
Safar, J.1
-
23
-
-
0038668790
-
Prion diseases: Cannibals and garbage piles
-
Aguzzi, A. & Heikenwalder, M. Prion diseases: cannibals and garbage piles. Nature 423, 127-129 (2003).
-
(2003)
Nature
, vol.423
, pp. 127-129
-
-
Aguzzi, A.1
Heikenwalder, M.2
-
24
-
-
0021884354
-
Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain
-
c.
-
(1985)
Nature
, vol.315
, pp. 331-333
-
-
Chesebro, B.1
-
25
-
-
0026423852
-
Spongrform encephalopathies. The prion's progress
-
Weissmann, C. Spongrform encephalopathies. The prion's progress. Natures 349, 569-571 (1991).
-
(1991)
Natures
, vol.349
, pp. 569-571
-
-
Weissmann, C.1
-
26
-
-
0028882424
-
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
-
Telling, G. C. et al. Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell 83, 79-90 (1995).
-
(1995)
Cell
, vol.83
, pp. 79-90
-
-
Telling, G.C.1
-
27
-
-
0025800143
-
A 'unified theory' of prion propagation
-
Weissmann, C. A 'unified theory' of prion propagation. Nature 352, 679-683 (1991).
-
(1991)
Nature
, vol.352
, pp. 679-683
-
-
Weissmann, C.1
-
28
-
-
0142184333
-
RNA molecules stimulate prion protein conversion
-
Deleault N. R., Lucassen, R. W. & Supattapone, S. RNA molecules stimulate prion protein conversion. Nature 425, 717-720 (2003).
-
(2003)
Nature
, vol.425
, pp. 717-720
-
-
Deleault, N.R.1
Lucassen, R.W.2
Supattapone, S.3
-
29
-
-
0030786717
-
Prion research: The next frontiers
-
Aguzzi, A. & Weissmann, C. Prion research: the next frontiers. Nature 389, 795-798 (1997).
-
(1997)
Nature
, vol.389
, pp. 795-798
-
-
Aguzzi, A.1
Weissmann, C.2
-
30
-
-
0037418828
-
Sc in vivo and antagonizes prion disease
-
Sc in vivo and antagonizes prion disease. Cell 113, 49-60 (2003).
-
(2003)
Cell
, vol.113
, pp. 49-60
-
-
Meier, P.1
-
31
-
-
0842281643
-
Mammalian prion biology. One century of evolving concepts
-
Aguzzi, A. & Polymenuou, M. Mammalian prion biology. One century of evolving concepts. Cell 116, 313-327 (2004).
-
(2004)
Cell
, vol.116
, pp. 313-327
-
-
Aguzzi, A.1
Polymenuou, M.2
-
32
-
-
0021023167
-
Aprotease-resistant protein is a structural component of the scrapie prion
-
McKinley, M. P., Bolton, D, C. & Prusiner, S. B. Aprotease-resistant protein is a structural component of the scrapie prion. Cell 35, 57-62 (1983).
-
(1983)
Cell
, vol.35
, pp. 57-62
-
-
McKinley, M.P.1
Bolton, D.C.2
Prusiner, S.B.3
-
33
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed, R. et al. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300, 486-489 (2003).
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
-
34
-
-
0030684056
-
Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie
-
Raeber, A. J. et al. Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie. EMBO J. 16, 6057-6065 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 6057-6065
-
-
Raeber, A.J.1
-
35
-
-
0242363656
-
Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis
-
Mallucci, G. et al. Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis. Science 302, 871-874 (2003). Shows that depletion of PrP from the neurons of transgenlc mice prevents the development of prion disease in infected mice.
-
(2003)
Science
, vol.302
, pp. 871-874
-
-
Mallucci, G.1
-
36
-
-
0022476747
-
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
-
Basler, K. et al. Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene. Cell 46, 417-428 (1986).
-
(1986)
Cell
, vol.46
, pp. 417-428
-
-
Basler, K.1
-
37
-
-
0027319326
-
Mice devoid of PrP are resistant to scrapie
-
Büeler, H. R. et al. Mice devoid of PrP are resistant to scrapie. Cell 73, 1339-1347 (1993). Shows that PrP is required for susceptibility to prion infections. An important milestone in prion research.
-
(1993)
Cell
, vol.73
, pp. 1339-1347
-
-
Büeler, H.R.1
-
38
-
-
0030054010
-
Normal host prion protein necessary for scrapie-induced neurotoxicity
-
Brandner, S. et al. Normal host prion protein necessary for scrapie-induced neurotoxicity. Nature 379, 339-343 (1996).
-
(1996)
Nature
, vol.379
, pp. 339-343
-
-
Brandner, S.1
-
39
-
-
0028535880
-
Sc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene
-
Sc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene. Mol. Med. 1, 19-30 (1994).
-
(1994)
Mol. Med.
, vol.1
, pp. 19-30
-
-
Büeler, H.1
-
40
-
-
0028703452
-
PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology
-
Manson, J. C., Clarke, A. R., McBride, P. A., McConnell, I. & Hope, J. PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology. Neurodegeneration 3, 331-340 (1994).
-
(1994)
Neurodegeneration
, vol.3
, pp. 331-340
-
-
Manson, J.C.1
Clarke, A.R.2
McBride, P.A.3
McConnell, I.4
Hope, J.5
-
41
-
-
12144289549
-
Specificity of lymphoreticular accumulation of prion protein for variant Creutzfeldt-Jakob disease
-
Hilton, D. A. et al. Specificity of lymphoreticular accumulation of prion protein for variant Creutzfeldt-Jakob disease. J. Clin. Pathol. 57, 300-302 (2004).
-
(2004)
J. Clin. Pathol.
, vol.57
, pp. 300-302
-
-
Hilton, D.A.1
-
42
-
-
0036169781
-
Distribution and accumulation of PrP in gut-associated and peripheral lymphoid tissue of scrapie-affected Suffolk sheep
-
Heggebo, R., Press, C. M., Gunnes, G., Gonzalez, L. & Jeffrey, M. Distribution and accumulation of PrP in gut-associated and peripheral lymphoid tissue of scrapie-affected Suffolk sheep. J. Gen. Virol. 83, 479-489 (2002).
-
(2002)
J. Gen. Virol.
, vol.83
, pp. 479-489
-
-
Heggebo, R.1
Press, C.M.2
Gunnes, G.3
Gonzalez, L.4
Jeffrey, M.5
-
43
-
-
28444460466
-
Cellular and sub-cellular localisation of PrP in the lymphoreticular system of mice and sheep
-
Jeffrey, M., McGovern, G., Martin, S., Goodsir, C. M. & Brown, K. L. Cellular and sub-cellular localisation of PrP in the lymphoreticular system of mice and sheep. Arch. Virol. Suppl. 16, 23-38 (2000).
-
(2000)
Arch. Virol. Suppl.
, vol.16
, pp. 23-38
-
-
Jeffrey, M.1
McGovern, G.2
Martin, S.3
Goodsir, C.M.4
Brown, K.L.5
-
44
-
-
0032883356
-
res in mule deer fawns (Odocoileus hemionus)
-
res in mule deer fawns (Odocoileus hemionus). J. Gen. Virol. 80, 2757-2764 (1999).
-
(1999)
J. Gen. Virol.
, vol.80
, pp. 2757-2764
-
-
Sigurdson, C.J.1
-
45
-
-
0037471890
-
Detection of disease-specific PrP in the distal ileum of cattle exposed orally to the agent of bovine spongiform encephalopathy
-
Terry, L. A. et al. Detection of disease-specific PrP in the distal ileum of cattle exposed orally to the agent of bovine spongiform encephalopathy. Vet. Rec. 152, 387-392 (2003).
-
(2003)
Vet. Rec.
, vol.152
, pp. 387-392
-
-
Terry, L.A.1
-
46
-
-
0032583714
-
Preliminary observations on the pathogenesis of experimental bovine spongiform encephalopathy (BSE): An update
-
Wells, G. A. et al. Preliminary observations on the pathogenesis of experimental bovine spongiform encephalopathy (BSE): an update. Vet. Rec. 142, 103-106 (1998).
-
(1998)
Vet. Rec.
, vol.142
, pp. 103-106
-
-
Wells, G.A.1
-
47
-
-
0242361687
-
Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease
-
Glatzel, M., Abela, E., Maissen, M. & Aguzzi, A. Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease. N. Engl. J. Med. 349, 1812-1820 (2003).
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 1812-1820
-
-
Glatzel, M.1
Abela, E.2
Maissen, M.3
Aguzzi, A.4
-
48
-
-
0036246734
-
New Zealand sheep with scrapie-susceptible PrP genotypes succumb to experimental challenge with a sheep-passaged scrapie isolate (SSBP/1)
-
Houston, E. F., Halliday, S. I., Jeffrey, M., Goldmann, W. & Hunter, N. New Zealand sheep with scrapie-susceptible PrP genotypes succumb to experimental challenge with a sheep-passaged scrapie isolate (SSBP/1). J. Gen. Virol. 83, 1247-1250 (2002).
-
(2002)
J. Gen. Virol.
, vol.83
, pp. 1247-1250
-
-
Houston, E.F.1
Halliday, S.I.2
Jeffrey, M.3
Goldmann, W.4
Hunter, N.5
-
49
-
-
0014930050
-
Pathogenesis of scrapie in the mouse: The role of the spleen
-
Fraser, H. & Dickinson, A. G. Pathogenesis of scrapie in the mouse: the role of the spleen. Nature 226, 462-163 (1970). Shows that PrP accumulates in lymphoid organs in the mouse model of scrapie.
-
(1970)
Nature
, vol.226
, pp. 462-163
-
-
Fraser, H.1
Dickinson, A.G.2
-
50
-
-
0035783509
-
Pathogenesis of prion diseases: Possible implications of microglial cells
-
Heppner, F. L., Prinz, M. & Aguzzi, A. Pathogenesis of prion diseases: possible implications of microglial cells. Prog. Brain Res. 132, 737-750 (2001).
-
(2001)
Prog. Brain Res.
, vol.132
, pp. 737-750
-
-
Heppner, F.L.1
Prinz, M.2
Aguzzi, A.3
-
51
-
-
0029784248
-
Evidence for an early inflammatory response in the central nervous system of mice with scrapie
-
Betmouni, S., Perry, V. H. & Gordon, J. L. Evidence for an early inflammatory response in the central nervous system of mice with scrapie. Neuroscience 74, 1-5 (1996).
-
(1996)
Neuroscience
, vol.74
, pp. 1-5
-
-
Betmouni, S.1
Perry, V.H.2
Gordon, J.L.3
-
52
-
-
0036267207
-
Atypical inflammation in the central nervous system in prion disease
-
Perry, V. H., Cunningham, C. & Boche, D. Atypical inflammation in the central nervous system in prion disease. Curr. Opin. Neurol. 15, 349-354 (2002).
-
(2002)
Curr. Opin. Neurol.
, vol.15
, pp. 349-354
-
-
Perry, V.H.1
Cunningham, C.2
Boche, D.3
-
53
-
-
0031444295
-
A crucial role for B cells in neuroinvasive scrapie
-
Klein, M. A. et al. A crucial role for B cells in neuroinvasive scrapie. Nature 390, 687-690 (1997).
-
(1997)
Nature
, vol.390
, pp. 687-690
-
-
Klein, M.A.1
-
54
-
-
0035047889
-
Complement facilitates early prion pathogenesis
-
Klein, M. A. et al. Complement facilitates early prion pathogenesis. Nature Med. 7, 488-492 (2001).
-
(2001)
Nature Med.
, vol.7
, pp. 488-492
-
-
Klein, M.A.1
-
55
-
-
0037297956
-
Prion pathogenesis in the absence of Toll-like receptor signalling
-
Prinz, M. et al. Prion pathogenesis in the absence of Toll-like receptor signalling. EMBO Rep. 4, 195-199 (2003).
-
(2003)
EMBO Rep.
, vol.4
, pp. 195-199
-
-
Prinz, M.1
-
56
-
-
0242499506
-
Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion
-
Prinz, M. et al. Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion. Nature 425, 957-962 (2003).
-
(2003)
Nature
, vol.425
, pp. 957-962
-
-
Prinz, M.1
-
57
-
-
0344021409
-
Prions and the immune system: A journey through gut, spleen, and nerves
-
Aguzzi, A. Prions and the immune system: a journey through gut, spleen, and nerves. Adv. Immunol. 81, 123-171 (2003).
-
(2003)
Adv. Immunol.
, vol.81
, pp. 123-171
-
-
Aguzzi, A.1
-
58
-
-
0014190760
-
Self-repllcation and scrapie
-
Griffith, J. S. Self-repllcation and scrapie. Nature 215, 1043-1044 (1967). A mathematician proposes that the scrapie agent might not be a traditional infectious agent but, instead, an infectious protein.
-
(1967)
Nature
, vol.215
, pp. 1043-1044
-
-
Griffith, J.S.1
-
59
-
-
0001530885
-
Further observations on the experimental production of scrapie in goats and sheep
-
Pattison, I. H. & Millson, G. C. Further observations on the experimental production of scrapie in goats and sheep. J. Comp. Pathol. 70, 182-193 (1960).
-
(1960)
J. Comp. Pathol.
, vol.70
, pp. 182-193
-
-
Pattison, I.H.1
Millson, G.C.2
-
60
-
-
0000446646
-
Distribution of the scrapie agent in the tissues of experimentally inoculated goats
-
Pattison, I. H. & Millson, G. C. Distribution of the scrapie agent in the tissues of experimentally inoculated goats. J. Comp. Pathol. 72, 233-244 (1962).
-
(1962)
J. Comp. Pathol.
, vol.72
, pp. 233-244
-
-
Pattison, I.H.1
Millson, G.C.2
-
61
-
-
0034797467
-
Transepithelial prion transport by M cells
-
Heppner, F. L. et al. Transepithelial prion transport by M cells. Nature Med. 7, 976-977 (2001).
-
(2001)
Nature Med.
, vol.7
, pp. 976-977
-
-
Heppner, F.L.1
-
62
-
-
0037377727
-
Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytes
-
Prinz, M. et al. Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytes. Am. J. Pathol. 162, 1103-1111 (2003).
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 1103-1111
-
-
Prinz, M.1
-
63
-
-
0037324858
-
Sc in lymphoid tissues of lambs experimentally exposed to the scrapie agent
-
Sc in lymphoid tissues of lambs experimentally exposed to the scrapie agent. J. Comp. Pathol. 128, 172-181 (2003).
-
(2003)
J. Comp. Pathol.
, vol.128
, pp. 172-181
-
-
Heggebo, R.1
-
65
-
-
0034798246
-
Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie
-
Aucouturier, P. et al. Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie. J. Clin. Invest. 108, 703-708 (2001).
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 703-708
-
-
Aucouturier, P.1
-
66
-
-
0037154263
-
Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells
-
Prinz, M. et al. Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells. Proc. Natl Acad. Sci. USA 99, 919-924 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 919-924
-
-
Prinz, M.1
-
67
-
-
0034686002
-
Impaired prion replication in spleens of mice lacking functional follicular dendritic cells
-
Montrasio, F. et al. Impaired prion replication in spleens of mice lacking functional follicular dendritic cells. Science 288, 1257-1259 (2000).
-
(2000)
Science
, vol.288
, pp. 1257-1259
-
-
Montrasio, F.1
-
68
-
-
0038618854
-
Follicuiar dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility
-
Mabbott, N. A., Young, J., McConnell, I. & Bruce, M. E. Follicuiar dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility. J. Virol. 77, 6845-6854 (2003).
-
(2003)
J. Virol.
, vol.77
, pp. 6845-6854
-
-
Mabbott, N.A.1
Young, J.2
McConnell, I.3
Bruce, M.E.4
-
69
-
-
0033930508
-
Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie
-
Mabbott, N. A., Mackay, F., Minns, F. & Bruce, M. E. Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie. Nature Med. 6, 719-720 (2000).
-
(2000)
Nature Med.
, vol.6
, pp. 719-720
-
-
Mabbott, N.A.1
Mackay, F.2
Minns, F.3
Bruce, M.E.4
-
70
-
-
0038186806
-
PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain
-
c is required for prions to reach the CNS after a peripheral exposure (either intraperitoneal or intravenous).
-
(1997)
Nature
, vol.389
, pp. 69-73
-
-
Blättler, T.1
-
72
-
-
0031759918
-
PrP expression in B lymphocytes is not required for prion neuroinvasion
-
Klein, M. A. et al. PrP expression in B lymphocytes is not required for prion neuroinvasion. Nature Med. 4, 1429-1433 (1998).
-
(1998)
Nature Med.
, vol.4
, pp. 1429-1433
-
-
Klein, M.A.1
-
73
-
-
0032746253
-
Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells
-
Brown, K. L. et al. Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells. Nature Med. 5, 1308-1312 (1999).
-
(1999)
Nature Med.
, vol.5
, pp. 1308-1312
-
-
Brown, K.L.1
-
74
-
-
0030582773
-
A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen
-
Forster, R. et al. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87, 1037-1047 (1996).
-
(1996)
Cell
, vol.87
, pp. 1037-1047
-
-
Forster, R.1
-
75
-
-
0029774786
-
Sequential appearance and accumulation of pathognomonic markers in the central nervous system of hamsters orally infected with scrapie
-
Beekes, M., Baldauf, E. & Diringer, H. Sequential appearance and accumulation of pathognomonic markers in the central nervous system of hamsters orally infected with scrapie. J. Gen. Virol. 77, 1925-1934 (1996).
-
(1996)
J. Gen. Virol.
, vol.77
, pp. 1925-1934
-
-
Beekes, M.1
Baldauf, E.2
Diringer, H.3
-
76
-
-
0031881510
-
Cerebral targeting indicates vagal spread of infection in hamsters fed with scrapie
-
Beekes, M., McBride, P. A. & Baldauf, E. Cerebral targeting indicates vagal spread of infection in hamsters fed with scrapie. J. Gen. Virol. 79, 601-607 (1998).
-
(1998)
J. Gen. Virol.
, vol.79
, pp. 601-607
-
-
Beekes, M.1
McBride, P.A.2
Baldauf, E.3
-
77
-
-
0034891027
-
Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion
-
Glatzel, M., Heppner, F. L., Albers, K. M. & Aguzzi, A. Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion. Neuron 31, 25-34 (2001).
-
(2001)
Neuron
, vol.31
, pp. 25-34
-
-
Glatzel, M.1
Heppner, F.L.2
Albers, K.M.3
Aguzzi, A.4
-
78
-
-
0026638150
-
Potent inhibition of scrapie-associated PrP accumulation by Congo red
-
Caughey, B. & Race, R. E. Potent inhibition of scrapie-associated PrP accumulation by Congo red. J. Neurochem. 59, 768-771 (1992).
-
(1992)
J. Neurochem.
, vol.59
, pp. 768-771
-
-
Caughey, B.1
Race, R.E.2
-
79
-
-
0023243085
-
Amphotericin B delays the incubation period of scrapie in intracerebrally inoculated hamsters
-
Pocchiari, M., Schmittinger, S. & Masullo, C. Amphotericin B delays the incubation period of scrapie in intracerebrally inoculated hamsters. J. Gen. Virol. 68, 219-223 (1987).
-
(1987)
J. Gen. Virol.
, vol.68
, pp. 219-223
-
-
Pocchiari, M.1
Schmittinger, S.2
Masullo, C.3
-
80
-
-
17344382240
-
Effectiveness of anthracycline against experimental prion disease in Syrian hamsters
-
Tagliavini, F. et al. Effectiveness of anthracycline against experimental prion disease in Syrian hamsters. Science 276, 1119-1122 (1997).
-
(1997)
Science
, vol.276
, pp. 1119-1122
-
-
Tagliavini, F.1
-
81
-
-
0027535855
-
Sulfated polyanion inhibition of scrapte-associated PrP accumulation in cultured cells
-
Caughey, B. & Raymond, G. J. Sulfated polyanion inhibition of scrapte-associated PrP accumulation in cultured cells. J. Virol. 67, 643-650 (1993).
-
(1993)
J. Virol.
, vol.67
, pp. 643-650
-
-
Caughey, B.1
Raymond, G.J.2
-
82
-
-
0033537348
-
Prophylactic potential of pentosan polysulphate in transmissible spongiform encephalopathies
-
Farquhar, C., Dickinson, A. & Bruce, M. Prophylactic potential of pentosan polysulphate in transmissible spongiform encephalopathies. Lancet 353, 117 (1999).
-
(1999)
Lancet
, vol.353
, pp. 117
-
-
Farquhar, C.1
Dickinson, A.2
Bruce, M.3
-
83
-
-
0034711993
-
Porphyrin and phthalocyanine antiscrapie compounds
-
Priola, S. A., Raines, A. & Caughey, W. S. Porphyrin and phthalocyanine antiscrapie compounds. Science 287, 1503-1506 (2000).
-
(2000)
Science
, vol.287
, pp. 1503-1506
-
-
Priola, S.A.1
Raines, A.2
Caughey, W.S.3
-
84
-
-
0035108195
-
Branched polyamines cure prion-infected neuroblastoma cells
-
Supattapone, S. et al. Branched polyamines cure prion-infected neuroblastoma cells. J. Virol. 75, 3453-3461 (2001).
-
(2001)
J. Virol.
, vol.75
, pp. 3453-3461
-
-
Supattapone, S.1
-
85
-
-
0034650634
-
Reversion of prion protein conformational changes by synthetic β-sheet breaker peptides
-
Soto, C. et al. Reversion of prion protein conformational changes by synthetic β-sheet breaker peptides. Lancet 355, 192-197 (2000).
-
(2000)
Lancet
, vol.355
, pp. 192-197
-
-
Soto, C.1
-
86
-
-
0029758220
-
Replication of scrapie in spleens of SCID mice follows reconstitution with wild-type mouse bone marrow
-
Fraser, H. et al. Replication of scrapie in spleens of SCID mice follows reconstitution with wild-type mouse bone marrow. J. Gen. Virol. 77, 1935-1940 (1996).
-
(1996)
J. Gen. Virol.
, vol.77
, pp. 1935-1940
-
-
Fraser, H.1
-
87
-
-
0033947543
-
Sites of prion protein accumulation in scrapie-infected mouse spleen revealed by immuno-electron microscopy
-
Jeffrey, M., McGovern, G., Goodsir, C. M., Brown, K. L. & Bruce, M. E. Sites of prion protein accumulation in scrapie-infected mouse spleen revealed by immuno-electron microscopy. J. Pathol. 191, 323-332 (2000).
-
(2000)
J. Pathol.
, vol.191
, pp. 323-332
-
-
Jeffrey, M.1
McGovern, G.2
Goodsir, C.M.3
Brown, K.L.4
Bruce, M.E.5
-
88
-
-
0036788143
-
CWD lymphoid cell targets in early and advanced chronic wasting disease of mule deer
-
CWD lymphoid cell targets in early and advanced chronic wasting disease of mule deer. J. Gen. Virol. 83, 2617-2628 (2002).
-
(2002)
J. Gen. Virol.
, vol.83
, pp. 2617-2628
-
-
Sigurdson, C.J.1
-
89
-
-
0025983158
-
Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease
-
Kitamoto, T., Muramoto, T., Mohri, S., Doh-ura, K. & Tateishi, J. Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease. J. Virol. 65, 6292-6295 (1991).
-
(1991)
J. Virol.
, vol.65
, pp. 6292-6295
-
-
Kitamoto, T.1
Muramoto, T.2
Mohri, S.3
Doh-Ura, K.4
Tateishi, J.5
-
90
-
-
0032480316
-
Turning off follicular dendritic cells
-
Mackay, F. & Browning, J. L. Turning off follicular dendritic cells. Nature 395, 26-27 (1998).
-
(1998)
Nature
, vol.395
, pp. 26-27
-
-
Mackay, F.1
Browning, J.L.2
-
91
-
-
0032842326
-
The requirement of membrane lymphotoxin for the presence of dendritic cells in lymphoid tissues
-
Wu, Q. et al. The requirement of membrane lymphotoxin for the presence of dendritic cells in lymphoid tissues. J. Exp. Med. 190, 629-638 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, pp. 629-638
-
-
Wu, Q.1
-
92
-
-
0032127279
-
Targeted disruption of the MyD88 gene results in loss of IL-1 - and IL-18-mediated function
-
Adachi, O. et al. Targeted disruption of the MyD88 gene results in loss of IL-1 - and IL-18-mediated function. Immunity 9, 143-150 (1998).
-
(1998)
Immunity
, vol.9
, pp. 143-150
-
-
Adachi, O.1
-
93
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi, H. et al. A Toll-like receptor recognizes bacterial DNA. Nature 408, 740-745 (2000).
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
-
94
-
-
0037143011
-
Postexposure prophylaxis against prion disease with a stimulator of innate immunity
-
Sethi, S., Lipford, G., Wagner, H. & Kretzschmar, H. Postexposure prophylaxis against prion disease with a stimulator of innate immunity. Lancet 360, 229-230 (2002).
-
(2002)
Lancet
, vol.360
, pp. 229-230
-
-
Sethi, S.1
Lipford, G.2
Wagner, H.3
Kretzschmar, H.4
-
95
-
-
0842343142
-
Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration
-
Heikenwalder, M. et al. Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration. Nature Med. 10, 187-192 (2004).
-
(2004)
Nature Med.
, vol.10
, pp. 187-192
-
-
Heikenwalder, M.1
-
96
-
-
0034068675
-
Role of spleen macrophages in the clearance of scrapie agent early in pathogenesis
-
Beringue, V. et al. Role of spleen macrophages in the clearance of scrapie agent early in pathogenesis. J. Pathol. 190, 495-502 (2000).
-
(2000)
J. Pathol.
, vol.190
, pp. 495-502
-
-
Beringue, V.1
-
97
-
-
1342329324
-
Prion protein is a component of the multimolecular signaling complex involved in T cell activation
-
Mattel, V. et al. Prion protein is a component of the multimolecular signaling complex involved in T cell activation. FEBS Lett. 560, 14-18 (2004).
-
(2004)
FEBS Lett.
, vol.560
, pp. 14-18
-
-
Mattel, V.1
-
98
-
-
0026637514
-
The prion protein gene: A role in mouse embryo genesis?
-
Manson, J. et al. The prion protein gene: a role in mouse embryogenesis? Development 115, 117-122 (1992).
-
(1992)
Development
, vol.115
, pp. 117-122
-
-
Manson, J.1
-
99
-
-
0025212147
-
Cellular isoform of the scrapie agent protein participates in lymphocyte activation
-
Cashman, N. R. et al. Cellular isoform of the scrapie agent protein participates in lymphocyte activation. Cell 61, 185-192 (1990).
-
(1990)
Cell
, vol.61
, pp. 185-192
-
-
Cashman, N.R.1
-
100
-
-
0035812752
-
Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies
-
Heppner, F. L. et al. Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies. Science 294, 178-182 (2001).
-
(2001)
Science
, vol.294
, pp. 178-182
-
-
Heppner, F.L.1
-
101
-
-
0035979274
-
Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody
-
Enari, M., Flechsig, E. & Weissmann, C. Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody. Proc. Natl Acad. Sci. USA 98, 9295-9299 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9295-9299
-
-
Enari, M.1
Flechsig, E.2
Weissmann, C.3
-
102
-
-
0035899413
-
Antibodies inhibit prion propagation and clear cell cultures of prion infectivity
-
Peretz, D. et al. Antibodies inhibit prion propagation and clear cell cultures of prion infectivity. Nature 412, 739-743 (2001).
-
(2001)
Nature
, vol.412
, pp. 739-743
-
-
Peretz, D.1
-
103
-
-
0037422133
-
Monoclonal antibodies inhibit prion replication and delay the development of prion disease
-
White, A. R. et al. Monoclonal antibodies inhibit prion replication and delay the development of prion disease. Nature 422, 80-83 (2003).
-
(2003)
Nature
, vol.422
, pp. 80-83
-
-
White, A.R.1
-
104
-
-
12144291519
-
Cross-linking cellular prion protein triggers neuronal apoptosis in vivo
-
Solforosi, L. et al. Cross-linking cellular prion protein triggers neuronal apoptosis in vivo. Science 303, 514-516 (2004).
-
(2004)
Science
, vol.303
, pp. 514-516
-
-
Solforosi, L.1
-
105
-
-
0036840139
-
Manipulation of lymphoid microenvironments in nonhuman primates by an inhibitor of the lymphotoxin pathway
-
Gommerman, J. L. et al. Manipulation of lymphoid microenvironments in nonhuman primates by an inhibitor of the lymphotoxin pathway. J. Clin. Invest. 110, 1359-1369 (2002).
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1359-1369
-
-
Gommerman, J.L.1
-
106
-
-
0036791019
-
Dominant-negative inhibition of prion replication in transgenic mice
-
Perrier, V et al. Dominant-negative inhibition of prion replication in transgenic mice. Proc. Natl Acad. Sci. USA 99, 13079-13084 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13079-13084
-
-
Perrier, V.1
-
107
-
-
0029825830
-
c) is required for scrapie spread within the central nervous system
-
c) is required for scrapie spread within the central nervous system. Proc. Natl Acad. Sci. USA 93, 13148-13151 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13148-13151
-
-
Brandner, S.1
-
108
-
-
0027491308
-
Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies
-
Prusiner, S. B. et al. Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies. Proc. Natl Acad. Sci. USA 90, 10608-10612 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10608-10612
-
-
Prusiner, S.B.1
-
109
-
-
0036849619
-
Induction of antibodies against murine full-length prion protein in wild-type mice
-
Koller, M. F., Grau, T. & Christen, P. Induction of antibodies against murine full-length prion protein in wild-type mice. J. Neuroimmunol. 132, 113-116 (2002).
-
(2002)
J. Neuroimmunol.
, vol.132
, pp. 113-116
-
-
Koller, M.F.1
Grau, T.2
Christen, P.3
-
110
-
-
1142297669
-
vCJD tissue distribution and transmission by transfusion - A worst-case scenario coming true?
-
Aguzzi, A. & Glatzel, M. vCJD tissue distribution and transmission by transfusion - a worst-case scenario coming true? Lancet 363, 411-412 (2004).
-
(2004)
Lancet
, vol.363
, pp. 411-412
-
-
Aguzzi, A.1
Glatzel, M.2
-
111
-
-
1142273431
-
Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion
-
Llewelyn, C. A. et al. Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion. Lancet 363, 417-421 (2004).
-
(2004)
Lancet
, vol.363
, pp. 417-421
-
-
Llewelyn, C.A.1
-
112
-
-
0035487106
-
Interventional strategies against prion diseases
-
Aguzzi, A., Glatzel, M., Montrasio, F., Prinz, M. & Heppner, F. L. Interventional strategies against prion diseases. Nature Rev. Neurosci. 2, 745-749 (2001).
-
(2001)
Nature Rev. Neurosci.
, vol.2
, pp. 745-749
-
-
Aguzzi, A.1
Glatzel, M.2
Montrasio, F.3
Prinz, M.4
Heppner, F.L.5
-
113
-
-
0342951746
-
A new variant of Creutzfeldt-Jakob disease in the UK
-
Will, R. G. et al. A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 347, 921-925 (1996).
-
(1996)
Lancet
, vol.347
, pp. 921-925
-
-
Will, R.G.1
-
114
-
-
0344342110
-
New variant of Creutzfeldt-Jakob disease in a 26-year-old French man
-
Chazot, G. et al. New variant of Creutzfeldt-Jakob disease in a 26-year-old French man. Lancet 347, 1181 (1996).
-
(1996)
Lancet
, vol.347
, pp. 1181
-
-
Chazot, G.1
-
115
-
-
0030600432
-
Spongiform encephalopathies: A suspicious signature
-
Aguzzi, A. & Weissmann, C. Spongiform encephalopathies: a suspicious signature. Nature 383, 666-667 (1996).
-
(1996)
Nature
, vol.383
, pp. 666-667
-
-
Aguzzi, A.1
Weissmann, C.2
-
116
-
-
0031015906
-
Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy
-
Hill, A. F., Zeidler, M., Ironside, J. & Collinge, J. Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy. Lancet 349, 99-100 (1997).
-
(1997)
Lancet
, vol.349
, pp. 99-100
-
-
Hill, A.F.1
Zeidler, M.2
Ironside, J.3
Collinge, J.4
-
117
-
-
0032829127
-
Scrapie pathogenesis in subclinically infected B-cell-deficient mice
-
Frigg, R., Klein, M. A., Hegyi, I., Zinkernagel, R. M. & Aguzzi, A. Scrapie pathogenesis in subclinically infected B-cell-deficient mice. J. Virol. 73, 9584-9588 (1999).
-
(1999)
J. Virol.
, vol.73
, pp. 9584-9588
-
-
Frigg, R.1
Klein, M.A.2
Hegyi, I.3
Zinkernagel, R.M.4
Aguzzi, A.5
-
118
-
-
0034675211
-
Transmission of BSE by blood transfusion in sheep
-
Houston, F., Foster, J. D., Chong, A., Hunter, N. & Bostock, C. J. Transmission of BSE by blood transfusion in sheep. Lancet 356, 999-1000 (2000). Shows that BSE prion infectivity circulates in the blood and is transmissible by transfusion. It was subsequently reported (reference 111) that a probable case of vCJD was contracted through blood transfusion.
-
(2000)
Lancet
, vol.356
, pp. 999-1000
-
-
Houston, F.1
Foster, J.D.2
Chong, A.3
Hunter, N.4
Bostock, C.J.5
-
119
-
-
0036843096
-
Transmission of prion diseases by blood transfusion
-
Hunter, N. et al. Transmission of prion diseases by blood transfusion. J. Gen. Virol. 83, 2897-2905 (2002).
-
(2002)
J. Gen. Virol.
, vol.83
, pp. 2897-2905
-
-
Hunter, N.1
-
120
-
-
0344420049
-
Human prion diseases: Epidemiology and integrated risk assessment
-
Glatzel, M. et al. Human prion diseases: epidemiology and integrated risk assessment. Lancet Neurol. 2, 757-763 (2003).
-
(2003)
Lancet Neurol.
, vol.2
, pp. 757-763
-
-
Glatzel, M.1
-
121
-
-
0035257228
-
Prions: Health scare and biological challenge
-
Aguzzi, A., Montrasio, F. & Kaeser, P. S. Prions: health scare and biological challenge. Nature Rev. Mol. Cell Biol. 2, 118-126 (2001).
-
(2001)
Nature Rev. Mol. Cell Biol.
, vol.2
, pp. 118-126
-
-
Aguzzi, A.1
Montrasio, F.2
Kaeser, P.S.3
-
122
-
-
0018832111
-
Virologic and neurohistologic findings in dairy goats affected with natural scrapie
-
Hadlow, W. J., Kennedy, R. C., Race, R. E. & Eklund, C. M. Virologic and neurohistologic findings in dairy goats affected with natural scrapie. Vet. Pathol. 17, 187-199 (1980).
-
(1980)
Vet. Pathol.
, vol.17
, pp. 187-199
-
-
Hadlow, W.J.1
Kennedy, R.C.2
Race, R.E.3
Eklund, C.M.4
-
123
-
-
0016259671
-
Course of experimentai scrapie virus infection in the goat
-
Hadlow, W. J. et al. Course of experimentai scrapie virus infection in the goat. J. Infect. Dis. 129, 559-567 (1974).
-
(1974)
J. Infect. Dis.
, vol.129
, pp. 559-567
-
-
Hadlow, W.J.1
-
124
-
-
0018893446
-
Replication of the scrapie agent in ocular neural tissues
-
Buyukmihci, N., Rorvik, M. & Marsh, R. F. Replication of the scrapie agent in ocular neural tissues. Proc. Natl Acad. Sci. USA 77, 1169-1171 (1980).
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 1169-1171
-
-
Buyukmihci, N.1
Rorvik, M.2
Marsh, R.F.3
-
125
-
-
0015519665
-
Spread of scrapie to sheep and goats by oral dosing with foetal membranes from scrapie-affected sheep
-
Pattison, I. H., Hoare, M. N., Jebbett, J. N. & Watson, W. A. Spread of scrapie to sheep and goats by oral dosing with foetal membranes from scrapie-affected sheep. Vet. Rec. 90, 465-468 (1972).
-
(1972)
Vet. Rec.
, vol.90
, pp. 465-468
-
-
Pattison, I.H.1
Hoare, M.N.2
Jebbett, J.N.3
Watson, W.A.4
-
126
-
-
0033521542
-
Mature follicular dendritic cell networks depend on expression of lymphotoxin-β receptor by radioresistant stromal cells and of lymphotoxin-β and tumor necrosis factor by B cells
-
Endres, R. et al. Mature follicular dendritic cell networks depend on expression of lymphotoxin-β receptor by radioresistant stromal cells and of lymphotoxin-β and tumor necrosis factor by B cells. J. Exp. Med. 189, 159-168 (1999).
-
(1999)
J. Exp. Med.
, vol.189
, pp. 159-168
-
-
Endres, R.1
-
127
-
-
0018936053
-
Oral transmission of kuru, Creutzfeldt-Jakob disease, and scrapie to nonhuman primates
-
Gibbs, C. J. Jr, Amyx, H. L. Bacote, A., Masters, C. L. & Gajdusek, D. C. Oral transmission of kuru, Creutzfeldt-Jakob disease, and scrapie to nonhuman primates. J. Infect. Dis. 142, 205-208 (1980).
-
(1980)
J. Infect. Dis.
, vol.142
, pp. 205-208
-
-
Gibbs Jr., C.J.1
Amyx, H.L.2
Bacote, A.3
Masters, C.L.4
Gajdusek, D.C.5
-
128
-
-
0014665121
-
Infection as the etiology of spongiform encephalopatny (Creutzfeldt-Jakob disease)
-
Gibbs, C. J. Jr & Gajdusek, D. C. Infection as the etiology of spongiform encephalopatny (Creutzfeldt-Jakob disease). Soence 165, 1023-1025 (1969).
-
(1969)
Soence
, vol.165
, pp. 1023-1025
-
-
Gibbs Jr., C.J.1
Gajdusek, D.C.2
-
129
-
-
0031292984
-
The Echigo-1 : A panencephalopathic strain of Creutzfeldt-Jakob disease: A passage to hamsters and ultrastructural studies
-
Liberski, P. P. & Mon, S. The Echigo-1 : a panencephalopathic strain of Creutzfeldt-Jakob disease: a passage to hamsters and ultrastructural studies. Folia Neuropathol. 35, 250-254 (1997).
-
(1997)
Folia Neuropathol.
, vol.35
, pp. 250-254
-
-
Liberski, P.P.1
Mon, S.2
-
130
-
-
0344844524
-
Humanized knock-in mice expressing chimeric prion protein showed varied susceptibility to different human prions
-
Taguchi, Y., Mohri, S., Ironside, J. W., Muramoto, T. & Kitamoto, T. Humanized knock-in mice expressing chimeric prion protein showed varied susceptibility to different human prions. Am. J. Pathol. 163, 2585-2593 (2003).
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 2585-2593
-
-
Taguchi, Y.1
Mohri, S.2
Ironside, J.W.3
Muramoto, T.4
Kitamoto, T.5
-
131
-
-
0030007616
-
Transmission of human prion diseases to rodents
-
Tateishi, J. Transmission of human prion diseases to rodents. Semin. Virol. 7, 175-180 (1996).
-
(1996)
Semin. Virol.
, vol.7
, pp. 175-180
-
-
Tateishi, J.1
-
132
-
-
18744362997
-
BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein
-
Asante, E. A. et al. BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein. EMBO J. 21, 6358-6366 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 6358-6366
-
-
Asante, E.A.1
-
133
-
-
0037495193
-
Comparison of the neuropathological characteristics of bovine spongiform encephalopathy (BSE) and variant Creutzfeldt-Jakob disease (vCJD) in mice
-
Brown, D. A., Bruce, M. E. & Fraser, J. R. Comparison of the neuropathological characteristics of bovine spongiform encephalopathy (BSE) and variant Creutzfeldt-Jakob disease (vCJD) in mice. Neuropathol. Appl. Neurobiol. 29, 262-272 (2003).
-
(2003)
Neuropathol. Appl. Neurobiol.
, vol.29
, pp. 262-272
-
-
Brown, D.A.1
Bruce, M.E.2
Fraser, J.R.3
-
134
-
-
0014201286
-
Transmission and passage of experimenal 'kuru' to chimpanzees
-
Gajdusek, D. C., Gibbs, C. J. Jr & Alpers, M. Transmission and passage of experimenal 'kuru' to chimpanzees. Science 155, 212-214 (1967). Shows that a human TSE, kuru, is transmissible to chimpanzees. Kuru was endemic in the Fore people of Papua New Guinea and transmitted between individuals through ritualistic cannibalism of the dead.
-
(1967)
Science
, vol.155
, pp. 212-214
-
-
Gajdusek, D.C.1
Gibbs Jr., C.J.2
Alpers, M.3
-
135
-
-
0029132280
-
First experimental transmission of fatal familial insomnia
-
Tateishi, J. et al. First experimental transmission of fatal familial insomnia. Nature 376, 434-435 (1995).
-
(1995)
Nature
, vol.376
, pp. 434-435
-
-
Tateishi, J.1
-
136
-
-
0021281297
-
Experimental transmission of human subacute spongiform encephalopathy to small rodents. IV. Positive transmission from a typical case of Gerstmann-Straussler-Scheinker's disease
-
Tateishi, J., Sato, Y., Nagara, H. & Boellaard, J. W. Experimental transmission of human subacute spongiform encephalopathy to small rodents. IV. Positive transmission from a typical case of Gerstmann-Straussler-Scheinker's disease. Acta Neuropathol. 64, 85-88 (1984).
-
(1984)
Acta Neuropathol.
, vol.64
, pp. 85-88
-
-
Tateishi, J.1
Sato, Y.2
Nagara, H.3
Boellaard, J.W.4
-
137
-
-
0025696814
-
Spongiform encephalopathy transmitted experimentally from Creutzfeldt-Jakob and familial Gerstmann-Straussler-Scheinker diseases
-
Baker, H. F., Duchen, L. W., Jacobs, J. M. & Ridley, R. M. Spongiform encephalopathy transmitted experimentally from Creutzfeldt-Jakob and familial Gerstmann-Straussler-Scheinker diseases. Brain 113, 1891-1909 (1990).
-
(1990)
Brain
, vol.113
, pp. 1891-1909
-
-
Baker, H.F.1
Duchen, L.W.2
Jacobs, J.M.3
Ridley, R.M.4
-
138
-
-
0036184403
-
Strain characterization of natural sheep scrapie and comparison with BSE
-
Bruce, M. E. et al. Strain characterization of natural sheep scrapie and comparison with BSE. J. Gen. Virol. 83, 695-704 (2002).
-
(2002)
J. Gen. Virol.
, vol.83
, pp. 695-704
-
-
Bruce, M.E.1
-
139
-
-
0022354703
-
Transmission of scrapie in hamsters
-
Prusiner, S. B., Cochran, S. P. & Alpers, M. P. Transmission of scrapie in hamsters, J. Infect. Dis. 152, 971-978 (1985).
-
(1985)
J. Infect. Dis.
, vol.152
, pp. 971-978
-
-
Prusiner, S.B.1
Cochran, S.P.2
Alpers, M.P.3
-
140
-
-
0034973230
-
Markedly increased susceptibility to natural sheep scrapie of transgenic mice expressing ovine PrP
-
Vilotte, J. L. et al. Markedly increased susceptibility to natural sheep scrapie of transgenic mice expressing ovine PrP. J. Virol. 75, 5977-5984 (2001).
-
(2001)
J. Virol.
, vol.75
, pp. 5977-5984
-
-
Vilotte, J.L.1
-
141
-
-
0032567088
-
The host range of chronic wasting disease is altered on passage in ferrets
-
Bartz, J. C., Marsh, R. F., McKenzie, D. I. & Aiken, J. M. The host range of chronic wasting disease is altered on passage in ferrets. Virology 251, 297-301 (1998).
-
(1998)
Virology
, vol.251
, pp. 297-301
-
-
Bartz, J.C.1
Marsh, R.F.2
McKenzie, D.I.3
Aiken, J.M.4
-
142
-
-
0037389545
-
res in BSE-infected bovine PrP transgenic mice
-
res in BSE-infected bovine PrP transgenic mice. Arch. Virol. 148, 677-691 (2003).
-
(2003)
Arch. Virol.
, vol.148
, pp. 677-691
-
-
Castilla, J.1
-
143
-
-
0033616722
-
Natural and experimental oral infection of nonhuman primates by bovine spongiform encephalopathy agents
-
Bons, N. et al. Natural and experimental oral infection of nonhuman primates by bovine spongiform encephalopathy agents. Proc. Natl Acad. Sci. USA 96, 4046-4051 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4046-4051
-
-
Bons, N.1
-
144
-
-
0029947694
-
BSE transmission to macaques
-
Lasmezas, C. I. et al. BSE transmission to macaques. Nature 381, 743-744 (1996).
-
(1996)
Nature
, vol.381
, pp. 743-744
-
-
Lasmezas, C.I.1
-
145
-
-
0028782015
-
Transmission of bovine spongiform encephalopathy and scrapie to mice: Strain variation and the species barrier
-
Bruce, M. et al. Transmission of bovine spongiform encephalopathy and scrapie to mice: strain variation and the species barrier. Philos. Trans. R. Soc. Lond. B 343, 405-411 (1994).
-
(1994)
Philos. Trans. R. Soc. Lond. B
, vol.343
, pp. 405-411
-
-
Bruce, M.1
-
146
-
-
0028779125
-
Transmission of feline spongiform encephalopathy to mice
-
Fraser, H. et al. Transmission of feline spongiform encephalopathy to mice. Vet. Rec. 134, 449 (1994).
-
(1994)
Vet. Rec.
, vol.134
, pp. 449
-
-
Fraser, H.1
-
147
-
-
0026558780
-
Identification of two biologically distinct strains of transmissible mink encephalopathy in hamsters
-
Bessen, R. A. & Marsh, R. F. Identification of two biologically distinct strains of transmissible mink encephalopathy in hamsters. J. Gen. Virol. 73, 329-334 (1992).
-
(1992)
J. Gen. Virol.
, vol.73
, pp. 329-334
-
-
Bessen, R.A.1
Marsh, R.F.2
-
148
-
-
4444325310
-
Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection
-
3 August (doi:10.1073/pnas.0404772101)
-
Polymenidou, M. et al. Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection. Proc. Natl Acad. Sci. USA 3 August 2004 (doi:10.1073/pnas.0404772101).
-
(2004)
Proc. Natl. Acad. Sci. USA
-
-
Polymenidou, M.1
|