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Volumn 18, Issue 2, 1998, Pages 118-125

Mice with gene targetted prion protein alterations show that PRNP, Sinc and Prni are congruent

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN;

EID: 0031942579     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng0298-118     Document Type: Article
Times cited : (174)

References (54)
  • 1
    • 0023669586 scopus 로고
    • A novel progressive spongiform encephalopathy in cattle
    • Wells, G.A.H. et al. A novel progressive spongiform encephalopathy in cattle. Vet. Rec. 121, 419-420 (1987).
    • (1987) Vet. Rec. , vol.121 , pp. 419-420
    • Wells, G.A.H.1
  • 2
    • 0002454682 scopus 로고
    • Über eine eigenartige herdformige Erkrankung des Zentralnervensystems. 2
    • Creutzfeldt, H.G. Über eine eigenartige herdformige Erkrankung des Zentralnervensystems. 2. Gesamte Neurol. Psychiatrie 57, 247-250 (1920).
    • (1920) Gesamte Neurol. Psychiatrie , vol.57 , pp. 247-250
    • Creutzfeldt, H.G.1
  • 3
    • 51849177198 scopus 로고
    • Über eigenartige Erkrankungen des Zentralnervensystems mit bemerkenswertem anatomischen Befunden (spastische Pseudoskterose-Encephalomyopathie mit diseminierten Degenerationsherden)
    • Jakob, A. Über eigenartige Erkrankungen des Zentralnervensystems mit bemerkenswertem anatomischen Befunden (spastische Pseudoskterose-Encephalomyopathie mit diseminierten Degenerationsherden). Z. Gesamte Neurol. Psychiatrie 64, 147-228 (1921).
    • (1921) Z. Gesamte Neurol. Psychiatrie , vol.64 , pp. 147-228
    • Jakob, A.1
  • 4
    • 51849178459 scopus 로고
    • Über eine eigenartige herediatarfamiläre Erkankung des Zentralnervensystems zugleich ein Beitrag zur Frage des vorzeitigen lokalen Alterns
    • Gerstmann, J., Straussler, E. & Scheinker, I. Über eine eigenartige herediatarfamiläre Erkankung des Zentralnervensystems zugleich ein Beitrag zur Frage des vorzeitigen lokalen Alterns. Z. Neurol. 154, 736-762 (1936).
    • (1936) Z. Neurol. , vol.154 , pp. 736-762
    • Gerstmann, J.1    Straussler, E.2    Scheinker, I.3
  • 5
    • 78651041685 scopus 로고
    • Degenerative disease of the central nervous system in New Guinea: Epidemic occurrence of "Kuru" in the native population
    • Gadjusek, D.C. & Zigas, V. Degenerative disease of the central nervous system in New Guinea: epidemic occurrence of "Kuru" in the native population. New Engl. J. Med. 257, 974-978 (1957).
    • (1957) New Engl. J. Med. , vol.257 , pp. 974-978
    • Gadjusek, D.C.1    Zigas, V.2
  • 6
    • 0022447484 scopus 로고
    • Fatal Familial Insomnia and dysautonomia with selective degeneration of thalamic nuclei
    • Lugaresi, E. et al. Fatal Familial Insomnia and dysautonomia with selective degeneration of thalamic nuclei. New Engl. J. Med. 315, 997-1003 (1986).
    • (1986) New Engl. J. Med. , vol.315 , pp. 997-1003
    • Lugaresi, E.1
  • 7
    • 0021879270 scopus 로고
    • Identification of prion amyloid filaments in scrapieinfected brain
    • DeArmond, S.J. et al. Identification of prion amyloid filaments in scrapieinfected brain. Cell 41, 221-235 (1985).
    • (1985) Cell , vol.41 , pp. 221-235
    • DeArmond, S.J.1
  • 8
    • 0022802258 scopus 로고
    • The major polypeptide of scrapie associated fibrils (SAF) has the same size, charge distribution and N-terminal protein sequence as predicted for the normal brain protein (PrP)
    • Hope, J. et al. The major polypeptide of scrapie associated fibrils (SAF) has the same size, charge distribution and N-terminal protein sequence as predicted for the normal brain protein (PrP). EMBO J. 10, 2591-2597 (1986).
    • (1986) EMBO J. , vol.10 , pp. 2591-2597
    • Hope, J.1
  • 9
    • 0027731067 scopus 로고
    • Neuropathology of spongiform encephalopathies in humans, B
    • Bell, J.E. & Ironside, J.W. Neuropathology of spongiform encephalopathies in humans, B. Med. Bull. 49, 738-777 (1993).
    • (1993) Med. Bull. , vol.49 , pp. 738-777
    • Bell, J.E.1    Ironside, J.W.2
  • 10
    • 0031053453 scopus 로고    scopus 로고
    • Pathology and immunocytochemistry of a Kuru Brain
    • Hainfellner, J.A. et al. Pathology and immunocytochemistry of a Kuru Brain. Brain Pathology 7, 547-553 (1997).
    • (1997) Brain Pathology , vol.7 , pp. 547-553
    • Hainfellner, J.A.1
  • 11
    • 0022476747 scopus 로고
    • Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
    • Basler, K. et al. Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene. Cell 46, 417-428 (1986).
    • (1986) Cell , vol.46 , pp. 417-428
    • Basler, K.1
  • 12
    • 49749206702 scopus 로고
    • Encephalopathy in mice produced with scrapie brain material
    • Chandler, R.L. Encephalopathy in mice produced with scrapie brain material. Lancet 1, 1378-1379 (1961).
    • (1961) Lancet , vol.1 , pp. 1378-1379
    • Chandler, R.L.1
  • 13
    • 0040716644 scopus 로고
    • Genetical control of the incubation period in mice of the neurological disease, scrapie
    • Dickinson, A.G. & MacKay, J.M.K. Genetical control of the incubation period in mice of the neurological disease, scrapie. Heredity 19, 279-288 (1964).
    • (1964) Heredity , vol.19 , pp. 279-288
    • Dickinson, A.G.1    MacKay, J.M.K.2
  • 14
    • 0014305661 scopus 로고
    • Identification of a gene which controls the incubation period of some strains of scrapie agent in mice
    • Dickinson, A.G., Meikle, V. & Fraser, H. Identification of a gene which controls the incubation period of some strains of scrapie agent in mice. J. Comp. Path. 78, 293-299 (1968).
    • (1968) J. Comp. Path. , vol.78 , pp. 293-299
    • Dickinson, A.G.1    Meikle, V.2    Fraser, H.3
  • 15
    • 0022530549 scopus 로고
    • Linkage of prion protein and scrapie incubation time genes
    • Carlson, G. et al. Linkage of prion protein and scrapie incubation time genes. Cell 46, 503-511 (1986).
    • (1986) Cell , vol.46 , pp. 503-511
    • Carlson, G.1
  • 16
    • 0024272862 scopus 로고
    • Genetics and polymorphism of the mouse prion gene complex: The control of scrapie incubation time
    • Carlson, G. et al. Genetics and polymorphism of the mouse prion gene complex: the control of scrapie incubation time. Mol. Cell. Biol. 8, 5528-5540 (1988).
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 5528-5540
    • Carlson, G.1
  • 17
    • 0023430390 scopus 로고
    • Linkage of the scrapie associated fibril protein (PrP) gene and Sinc using congenic mice and restriction fragment length polymorphism analysis
    • Hunter, N., Hope, J., McConnell, I. & Dickinson, A.G. Linkage of the scrapie associated fibril protein (PrP) gene and Sinc using congenic mice and restriction fragment length polymorphism analysis. J. Gen. Virol. 68, 2711-2716 (1987).
    • (1987) J. Gen. Virol. , vol.68 , pp. 2711-2716
    • Hunter, N.1    Hope, J.2    McConnell, I.3    Dickinson, A.G.4
  • 18
    • 0023467393 scopus 로고
    • Distinct prion proteins in short and long scrapie incubation period mice
    • Westaway, D. et al. Distinct prion proteins in short and long scrapie incubation period mice. Cell 51, 561-662 (1987).
    • (1987) Cell , vol.51 , pp. 561-662
    • Westaway, D.1
  • 19
    • 0027447693 scopus 로고
    • Delimiting the location of the scrapie prion incubation time gene on chromosome 2 of the mouse
    • Carlson, G., Ebeling, C., Torchia, M., Westaway, D. & Prusiner, S.B. Delimiting the location of the scrapie prion incubation time gene on chromosome 2 of the mouse. Genetics 133, 979-988 (1993).
    • (1993) Genetics , vol.133 , pp. 979-988
    • Carlson, G.1    Ebeling, C.2    Torchia, M.3    Westaway, D.4    Prusiner, S.B.5
  • 20
    • 0025186539 scopus 로고
    • Analysis of linkage between scrapie incubation period and the prion protein gene in mice
    • Race, R.E., Graham, K., Ernst, D. & Chesebro, B. Analysis of linkage between scrapie incubation period and the prion protein gene in mice. J. Gen. Virol. 71, 493-497 (1990).
    • (1990) J. Gen. Virol. , vol.71 , pp. 493-497
    • Race, R.E.1    Graham, K.2    Ernst, D.3    Chesebro, B.4
  • 21
    • 0026099887 scopus 로고
    • The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: Implications for the nature of the agent and host control of pathogenesis
    • Bruce, M.E., McConnell, I., Fraser, H. & Dickinson, A.G. The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis. J. Gen. Virol. 72, 595-603 (1991).
    • (1991) J. Gen. Virol. , vol.72 , pp. 595-603
    • Bruce, M.E.1    McConnell, I.2    Fraser, H.3    Dickinson, A.G.4
  • 22
    • 0026739272 scopus 로고
    • Are Sinc and the PrP gene congruent -evidence from PrP gene analysis in Sinc congenic mice
    • Hunter, N. et al. Are Sinc and the PrP gene congruent -evidence from PrP gene analysis in Sinc congenic mice. J. Gen. Virol 73, 2751-2755 (1992).
    • (1992) J. Gen. Virol , vol.73 , pp. 2751-2755
    • Hunter, N.1
  • 23
    • 0025850771 scopus 로고
    • Paradoxical shortening of scrapie incubation times by expression of prion protein transgenes derived from long incubation period mice
    • Westaway, D. et al. Paradoxical shortening of scrapie incubation times by expression of prion protein transgenes derived from long incubation period mice. Neuron 7, 59-68 (1991).
    • (1991) Neuron , vol.7 , pp. 59-68
    • Westaway, D.1
  • 24
    • 0028276015 scopus 로고
    • Prion isolate specified allotype interactions between the cellular and scrapie prion proteins in congenic and transgenic mice
    • Carlson, G. et al. Prion isolate specified allotype interactions between the cellular and scrapie prion proteins in congenic and transgenic mice. Proc. Natl. Acad. Sci. USA 91, 5690-5694 (1994).
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 5690-5694
    • Carlson, G.1
  • 25
    • 0021846543 scopus 로고
    • Genetic control of amyloid plaque production and incubation period in scrapie infected mice
    • Bruce, M.E. & Dickinson, A.G. Genetic control of amyloid plaque production and incubation period in scrapie infected mice. J. Neuropath. Exp. Neurol. 44, 285-294 (1985).
    • (1985) J. Neuropath. Exp. Neurol. , vol.44 , pp. 285-294
    • Bruce, M.E.1    Dickinson, A.G.2
  • 26
    • 0029092955 scopus 로고
    • Double replacement gene targetting for the production of a series of mouse strains with different prion protein gene alterations
    • Moore, R.C. et al. Double replacement gene targetting for the production of a series of mouse strains with different prion protein gene alterations Biotechnology 13, 999-1004 (1995).
    • (1995) Biotechnology , vol.13 , pp. 999-1004
    • Moore, R.C.1
  • 27
    • 0026635749 scopus 로고
    • A new mouse embryonic stem cell line with good germ line contribution and targetting frequency
    • Magin, T.M., McWhir, J. & Melton, D.W. A new mouse embryonic stem cell line with good germ line contribution and targetting frequency. Nucleic Acids Res. 20, 3795-3796 (1992).
    • (1992) Nucleic Acids Res. , vol.20 , pp. 3795-3796
    • Magin, T.M.1    McWhir, J.2    Melton, D.W.3
  • 28
    • 0030902872 scopus 로고    scopus 로고
    • Genetic variation among 129 substrains and its importance for targetted mutagenesis in mice
    • Simpson, E.M. et al. Genetic variation among 129 substrains and its importance for targetted mutagenesis in mice. Nature Genet. 16, 19-27 (1997).
    • (1997) Nature Genet. , vol.16 , pp. 19-27
    • Simpson, E.M.1
  • 29
    • 0028703452 scopus 로고
    • PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology
    • Manson, J.C., Clarke, A.R., McBride, P.A., McConnell, I. & Hope, J. PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology. Neurodegeneration 13, 331-340 (1994).
    • (1994) Neurodegeneration , vol.13 , pp. 331-340
    • Manson, J.C.1    Clarke, A.R.2    McBride, P.A.3    McConnell, I.4    Hope, J.5
  • 30
    • 0028275018 scopus 로고
    • Structure and polymorphism of the mouse prion protein gene
    • Westaway, D. et al. Structure and polymorphism of the mouse prion protein gene. Proc. Natl. Acad. Sci. USA 91, 6418-6422 (1994).
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6418-6422
    • Westaway, D.1
  • 31
    • 0031033177 scopus 로고    scopus 로고
    • Characterisation of two promoters for prion protein (PrP) gene expression in neuronal cells
    • Baybutt, H. & Manson, J. Characterisation of two promoters for prion protein (PrP) gene expression in neuronal cells. Gene 184, 125-131 (1997).
    • (1997) Gene , vol.184 , pp. 125-131
    • Baybutt, H.1    Manson, J.2
  • 32
    • 0025244011 scopus 로고
    • Transgenic studies implicate interactions between homologous PrP isoforms in scrapie prion replication
    • Prusiner, S.B. et al. Transgenic studies implicate interactions between homologous PrP isoforms in scrapie prion replication. Cell 63, 673-686 (1990).
    • (1990) Cell , vol.63 , pp. 673-686
    • Prusiner, S.B.1
  • 33
    • 0029740354 scopus 로고    scopus 로고
    • Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice
    • Telling, G.C. et al. Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice. Genes Devel. 10, 1736-1750 (1996).
    • (1996) Genes Devel. , vol.10 , pp. 1736-1750
    • Telling, G.C.1
  • 34
    • 0029863648 scopus 로고    scopus 로고
    • Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie
    • Fischer, M. et al. Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. EMBO J. 15, 1255-1264 (1996).
    • (1996) EMBO J. , vol.15 , pp. 1255-1264
    • Fischer, M.1
  • 35
    • 0027319326 scopus 로고
    • Mice devoid of PrP are resistant to scrapie
    • Bueler, H. et al. Mice devoid of PrP are resistant to scrapie. Cell 73, 1339-1347 (1993).
    • (1993) Cell , vol.73 , pp. 1339-1347
    • Bueler, H.1
  • 36
    • 0027491308 scopus 로고
    • Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies
    • Prusiner, S.B. et al. Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies. Proc. Natl. Acad. Sci. USA 90, 10608-10612 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10608-10612
    • Prusiner, S.B.1
  • 37
    • 0028820122 scopus 로고
    • Accumulation of proteinase K-resistant Prion protein (PrP) is restricted by the expression level of normal PrP in mice inoculated with a mouse-adapted strain of the Creutzfeldt-Jakob Disease agent
    • Sakaguchi, S. et al. Accumulation of proteinase K-resistant Prion protein (PrP) is restricted by the expression level of normal PrP in mice inoculated with a mouse-adapted strain of the Creutzfeldt-Jakob Disease agent. J. Virol. 69, 7586-7592 (1995).
    • (1995) J. Virol. , vol.69 , pp. 7586-7592
    • Sakaguchi, S.1
  • 38
    • 0002540771 scopus 로고
    • Expression of the PrP gene in the brain of Sinc congenic mice and its relationship to the development of scrapie
    • Manson, J.C., McBride, P. & Hope, J. Expression of the PrP gene in the brain of Sinc congenic mice and its relationship to the development of scrapie. Neurodegeneration 1, 45-52 (1992).
    • (1992) Neurodegeneration , vol.1 , pp. 45-52
    • Manson, J.C.1    McBride, P.2    Hope, J.3
  • 39
    • 0040393220 scopus 로고
    • Separation and properties of cellular and scrapie prion proteins
    • Meyer, R.K. et al. Separation and properties of cellular and scrapie prion proteins. Proc. Natl. Acad. Sci. USA 83, 2310-2314 (1986)
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 2310-2314
    • Meyer, R.K.1
  • 40
    • 0029781211 scopus 로고    scopus 로고
    • Protease resistant PrP deposition in brain and non-central nervous system tissues of a murine model of bovine spongiform encephalopathy
    • Farquhar, CF. et al. Protease resistant PrP deposition in brain and non-central nervous system tissues of a murine model of bovine spongiform encephalopathy. J. Gen. Virol. 1941-1946 (1996).
    • (1996) J. Gen. Virol. , pp. 1941-1946
    • Farquhar, C.F.1
  • 41
    • 0014192069 scopus 로고
    • Distribution of experimentally induced scrapie lesions in the brain
    • Fraser, H. & Dickinson, A.C. Distribution of experimentally induced scrapie lesions in the brain. Nature 216, 1310-1311 (1967).
    • (1967) Nature , vol.216 , pp. 1310-1311
    • Fraser, H.1    Dickinson, A.C.2
  • 42
    • 0014308027 scopus 로고
    • The sequential development of the brain lesions of scrapie in three strains of mice
    • Fraser, H. & Dickinson, A.G. The sequential development of the brain lesions of scrapie in three strains of mice. J. Comp. Path. 78, 301-311 (1968).
    • (1968) J. Comp. Path. , vol.78 , pp. 301-311
    • Fraser, H.1    Dickinson, A.G.2
  • 43
    • 0020521924 scopus 로고
    • Genetic control of scrapie and Creutzfeldt-Jakob disease in mice
    • Kingsbury, D.T. et al. Genetic control of scrapie and Creutzfeldt-Jakob disease in mice. J. Immunology 131, 491-496 (1983).
    • (1983) J. Immunology , vol.131 , pp. 491-496
    • Kingsbury, D.T.1
  • 44
    • 0028782015 scopus 로고
    • Transmission of bovine spongiform encephalopathy and scrapie to mice: Strain variation and the species barrier
    • Bruce, M., Chree, A., McConnell, I. & Wells, G.A.H. Transmission of bovine spongiform encephalopathy and scrapie to mice: strain variation and the species barrier. Phil. Trans. R. Soc. Lond, B 343, 405-411 (1994).
    • (1994) Phil. Trans. R. Soc. Lond, B , vol.343 , pp. 405-411
    • Bruce, M.1    Chree, A.2    McConnell, I.3    Wells, G.A.H.4
  • 45
    • 0016905630 scopus 로고
    • The pathology of natural and experimental scrapie
    • ed. R.H. Kimberlin, Amsterdam
    • Fraser, H. The pathology of natural and experimental scrapie. In: Slow Virus Diseases of Animals and Man (ed. R.H. Kimberlin, Amsterdam) 267-305 (1976).
    • (1976) Slow Virus Diseases of Animals and Man , pp. 267-305
    • Fraser, H.1
  • 46
    • 0024366602 scopus 로고
    • Precise targetting of the pathology of the sialoglycoprotein, PrP, and vacuolar degeneration in mouse scrapie
    • Bruce, M.E., McBride, P.A. & Farquhar, C.F. Precise targetting of the pathology of the sialoglycoprotein, PrP, and vacuolar degeneration in mouse scrapie. Neurosci. Lett. 102, 1-6 (1989).
    • (1989) Neurosci. Lett. , vol.102 , pp. 1-6
    • Bruce, M.E.1    McBride, P.A.2    Farquhar, C.F.3
  • 47
    • 0026729945 scopus 로고
    • Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters
    • Hecker, R. et al. Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters. Genes Devel. 6, 1213-1228 (1992).
    • (1992) Genes Devel. , vol.6 , pp. 1213-1228
    • Hecker, R.1
  • 48
    • 0023613953 scopus 로고
    • Rapid and efficient site-specific mutagenesis without phenotypic selection
    • Kunkel, T.A., Roberts, J.D. & Zakour, R.A. Rapid and efficient site-specific mutagenesis without phenotypic selection. Meth. Enzymol. 154, 367-382 (1987).
    • (1987) Meth. Enzymol. , vol.154 , pp. 367-382
    • Kunkel, T.A.1    Roberts, J.D.2    Zakour, R.A.3
  • 49
    • 0024494423 scopus 로고
    • Germline transmission and expression of a corrected HPRT gene produced by gene targetting in embryonic stem cells
    • Thompson, S., Clarke, A.R., Pow, A.M., Hooper, M.L. & Melton, D.W. Germline transmission and expression of a corrected HPRT gene produced by gene targetting in embryonic stem cells. Cell 56, 313-321 (1989).
    • (1989) Cell , vol.56 , pp. 313-321
    • Thompson, S.1    Clarke, A.R.2    Pow, A.M.3    Hooper, M.L.4    Melton, D.W.5
  • 50
    • 0026801020 scopus 로고
    • Transmission of bovine spongiform encephalopathy and scrapie to mice
    • Fraser, H., Bruce, M.E., Chree, A., McConnell, I. & Wells, G.A.H. Transmission of bovine spongiform encephalopathy and scrapie to mice. J. Gen. Virol. 73, 1891-1897 (1992).
    • (1992) J. Gen. Virol. , vol.73 , pp. 1891-1897
    • Fraser, H.1    Bruce, M.E.2    Chree, A.3    McConnell, I.4    Wells, G.A.H.5
  • 51
    • 0014787893 scopus 로고
    • The unlabelled antibodyenzyme method of immunohistochemistry. Preparation of soluble antigenantibody complex (horse-radish peroxidase-antihorseradish peroxidase) and its use in identifying spirochetes
    • Sternberger, L.A., Hardy, P.H., Cuculis, J.J. & Meyer, H. The unlabelled antibodyenzyme method of immunohistochemistry. Preparation of soluble antigenantibody complex (horse-radish peroxidase-antihorseradish peroxidase) and its use in identifying spirochetes. J. Histochem. Cytochem. 18, 315-333 (1970).
    • (1970) J. Histochem. Cytochem. , vol.18 , pp. 315-333
    • Sternberger, L.A.1    Hardy, P.H.2    Cuculis, J.J.3    Meyer, H.4
  • 52
    • 0024307533 scopus 로고
    • Postmortem immunodiagnosis of scrapie and bovine spongiform encephalopathy
    • Farquhar, C.F., Somerville, R.A. & Ritchie, L.A. Postmortem immunodiagnosis of scrapie and bovine spongiform encephalopathy J. Virol. Meth. 24, 215-222 (1989).
    • (1989) J. Virol. Meth. , vol.24 , pp. 215-222
    • Farquhar, C.F.1    Somerville, R.A.2    Ritchie, L.A.3
  • 54
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685 (1970).
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1


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