Microglial activation varies in different models of Creutzfeldt-Jakob disease

Journal of Virology

Volumn 73, Issue 6, 1999, Pages 5089-5097

  Baker, Christopher A ^a   Lu, Zhi Yun ^a   Zaitsev, Igor ^a   Manuelidis, Laura ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN S; CHEMOKINE RECEPTOR CCR5; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL MODEL; ARTICLE; CREUTZFELDT JAKOB DISEASE; GENE EXPRESSION; HAMSTER; MICROGLIA; MOUSE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; VIRUS INFECTION; VIRUS INFECTIVITY;

EID: 0345188622     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.6.5089-5097.1999     Document Type: Article

References (69)

1. Aguzzi, A., and C. Weissmann. 1997. Prion research: the next frontiers. Nature 389:795-798.
2. Akowitz, A., T. Sklaviadis, E. E. Manuelidis, and L. Manuelidis. 1990. Nuclease-resistant polyadenylated RNAs of significant size are detected by PCR in highly purified Creutzfeldt-Jakob disease preparations. Microb. Pathog. 9:33-45.
3. Akowitz, A., T. Sklaviadis, and L. Manuelidis. 1994. Endogenous viral complexes with long RNA cosediment with the agent of Creutzfeldt-Jakob disease. Nucleic Acids Res. 22:1101-1107.
4. Berglund, E. O., and B. Ranscht. 1994. Molecular cloning and in situ localization of the human contactin gene (CNTN1) on chromosome 12q11-q12. Genomics 21:571-582.
5. Bruce, M. E., I. McConnell, H. Fraser, and A. G. Dickinson. 1991. The disease characteristics of different strains of scrapie in Sine congenic mouse lines: implications for the nature of the agent and host control of pathogenesis. J. Gen. Virol. 72:595-603.
6. Büeler, H., A. Aguzzi, A. Sailer, R.-A. Greiner, P. Autenried, M. Auget, and C. Weissmann. 1993. Mice devoid of PrP are resistant to scrapie. Cell 73:1339-1347.
7. Campbell, I. L., M. Eddleston, P. Kemper, M. B. A. Oldstone, and M. V. Hobbs. 1994. Activation of cerebral cytokine gene expression and its correlation with onset of reactive astrocyte and acute-phase response gene expression in scrapie. J. Virol. 68:2383-2387.
8. Chen, J. J., Y. N. Sun, and G. J. Nabel. 1998. Regulation of the proinflammatory effects of Fas ligand (CD95L). Science 282:1714-1717.
9. Czub, M., S. Czub, M. Rappold, S. Mazgareanu, S. Schwender, M. Demuth, A. Hein, and R. Dörries. 1995. Murine leukemia virus-induced neurodegeneration of rats: enhancement of neuropathogenicity correlates with enhanced viral tropism for macrophages, microglia, and brain vascular cells. Virology 214:239-244.
10. Dandoy-Dron, F., F. Guillo, L. Benboudjema, J.-P. Deslys, C. Lasmezas, D. Dormont, M. G. Tovey, and M. Dron. 1998. Gene expression in scrapie: cloning of a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts. J. Biol. Chem. 273:7691-7697.
11. Diringer, H., M. Beekes, M. Ozel, D. Simon, I. Queck, F. Cardone, M. Pocchiari, and J. W. Ironside. 1997. Highly infectious purified preparations of disease-specific amyloid of transmissible spongiform encephalopathies are not devoid of nucleic acids of viral size. Intervirology 40:238-246.
12. Duguid, J., and C. Trzepacz. 1993. Major histocompatibility complex genes have an increased brain expression after scrapie infection. Proc. Natl. Acad. Sci. USA 90:114-117.
13. Eklund, C. M., R. C. Kennedy, and W. J. Hadlow. 1967. Pathogenesis of scrapie virus infection in the mouse. J. Infect. Dis. 117:15-22.
14. Fischer, M., T. Rülicke, A. Raeber, A. Sailer, M. Moser, B. Oesch, S. Brandner, A. Aguzzi, and C. Weissman. 1996. Prion protein (PrP) with aminoproximal deletions restoring susceptibility of knockout mice to scrapie. EMBO J. 15:1255-1264.
15. Galasso, J. M., J. K. Harrison, and F. S. Silverstein. 1998. Excitotoxic brain injury stimulates expression of the chemokine receptor CCR5 in neonatal rats. Am. J. Pathol. 153:1631-1640.
16. Gendelman, H. E., S. A. Lipton, M. Tardieu, M. I. Bukrinsky, and H. S. Nottet. 1994. The neuropathogenesis of HIV-1 infection. J. Leukocyte Biol. 56:389-398.
17. Giese, A., D. R. Brown, M. H. Groschup, C. Feldmann, I. Haist, and H. A. Kretzschmar. 1998. Role of microglia in neuronal cell death and prion disease. Brain Pathol. 8:449-457.
18. He, J., Y. Chen, M. Farzan, H. Choe, A. Ohagen, S. Gartner, J. Busciglio, X. Yang, W. Hofmann, W. Newman, C. R. Mackay, J. Sodroski, and D. Gabuzda. 1997. CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia. Nature 385:645-649.
19. Hsiao, K. K., D. Groth, M. Scott, S.-L. Yang, H. Serban, D. Rapp, D. Foster, M. Torchia, S. J. DeArmond, and S. B. Prusiner. 1994. Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein. Proc. Natl. Acad. Sci. USA 91:9126-9130.
20. Jiang, Y., M. N. Salafranca, S. Adhikari, Y. Xia, L. Feng, M. K. Sonntag, C. M. deFiebre, N. A. Pennell, W. J. Streit, and J. K. Harrison. 1998. Chemokine receptor expression in cultured glia and rat experimental allergic encephalomyelitis. J. Neuroimmunol. 86:1-12.
21. Ju, W. K., K. J. Park, E. K. Choi, J. Kim, R. I. Carp, H. M. Wisniewski, and Y. S. Kim. 1998. Expression of inducible nitric oxide synthase in the brains of scrapie-infected mice. J. Neurovirol. 4:445-450.
22. Kay, D. G., C. Gravel, Y. Robitaille, and P. Jolicoeur. 1991. Retrovirus-induced spongiform myeloencephalopathy in mice: regional distribution of infected target cells and neuronal loss occurring in the absence of viral expression in neurons. Proc. Natl. Acad. Sci. USA 88:1281-1285.
23. Kiefer, R., W. J. Streit, K. V. Toyka, G. W. Kreutzberg, and H.-P. Hartung. 1995. Transforming growth factor-β1: a lesion-associated cytokine of the nervous system. Int. J. Dev. Neurosci. 13:331-339.
24. Klein, M. A., R. Frigg, E. Flechsig, A. J. Raeber, U. Kalinke, H. Bluethmann, F. Bootz, M. Suter, R. M. Zinkernagel, and A. Aguzzi. 1997. A crucial role for B cells in neuroinvasive scrapie. Nature 390:687-690.
25. Kordek, R., V. R. Nerurkar, P. P. Liberski, S. Isaacson, R. Yanagihara, and D. C. Gajdusek. 1996. Heightened expression of tumor necrosis factor-α, interleukin-1α, and glial fibrillary acidic protein in experimental Creutzfeldt-Jakob disease in mice. Proc. Natl. Acad. Sci. USA 93:9754-9758.
26. Lasmezas, C. I., J. P. Deslys, O. Robain, A. Jaegly, V. Beringue, J. M. Peyrin, J. G. Fournier, J. J. Hauw, J. Rossier, and D. Dormant. 1997. Transmission of the BSE agent to mice in the absence of detectable abnormal prion protein. Science 275:402-405.
27. Lemere, C. A., J. S. Munger, G.-P. Shi, L. Natkin, C. Haass, H. A. Chapman, and D. J. Selkoe. 1995. The lysosomal cysteine protease, cathepsin S, is increased in Alzheimer's disease and Down syndrome brain. Am. J. Pathol. 146:848-860.
28. Lisitsyn, N., N. Lisitsyn, and M. Wigler. 1993. Cloning the differences between two complex genomes. Science 259:946-951.
29. Luster, A. D. 1998. Chemokines - chemotactic cytokines that mediate inflammation. N. Engl. J. Med. 338:436-445.
30. Lynch, W. P., E. Y. Snyder, L. Qualtiere, J. L. Portis, and A. H. Sharpe. 1996. Late virus replication events in microglia are required for neurovirulent retrovirus-induced spongiform neurodegeneration: evidence from neural progenitor-derived chimeric mouse brains. J. Virol. 70:8896-8907.
31. Manuelidis, E. E., E. J. Gorgacs, and L. Manuelidis. 1978. Viremia in experimental Creutzfeldt-Jakob disease. Science 200:1069-1071.
32. Manuelidis, E. E., J. H. Kim, J. R. Mericangas, and L. Manuelidis. 1985. Transmission to animals of Creutzfeldt-Jakob disease from human blood. Lancet 2:896-897.
33. Manuelidis, L. 1994. The dimensions of Creutzfeldt-Jakob disease. Transfusion 34:915-928.
34. Manuelidis, L. 1998. Vaccination with an attenuated Creutzfeldt-Jakob disease strain prevents expression of a virulent agent. Proc. Natl. Acad. Sci. USA 95:2520-2525.
35. Manuelidis, L., and W. Fritch. 1996. Infectivity and host responses in Creutzfeldt-Jakob disease. Virology 215:46-59.
36. Manuelidis, L., W. Fritch, and Y.-G. Xi. 1997. Evolution of a strain of CJD that induces BSE-like plaques. Science 277:94-98.
37. Manuelidis, L., W. Fritch, and I. Zaitsev. 1998. Dapsone to delay symptoms in Creutzfeldt-Jakob disease. Lancet 352:456.
38. Manuelidis, L., G. Murdoch, and E. Manuelidis. 1988. Possible involvement of retroviral elements in human dementias. CIBA Found. Symp. 135:117-134.
39. Manuelidis, L., T. Sklaviadis, A. Akowitz, and W. Fritch. 1995. Viral particles are required for infection in neurodegenerative Creutzfeldt-Jakob disease. Proc. Natl. Acad. Sci. USA 92:5124-5128.
40. Manuelidis, L., D. M. Tesin, T. Sklaviadis, and E. E. Manuelidis. 1987. Astrocyte gene expression in Creutzfeldt-Jakob disease. Proc. Natl. Acad. Sci. USA 84:5937-5941.
41. Mathieu-Daude, F., R. Cheng, J. Welsh, and M. McClelland. 1996. Screening of differentially amplified cDNA products from RNA arbitrarily primed PCR fingerprints using single strand conformation polymorphism (SSCP) gels. Nucleic Acids Res. 24:1504-1507.
42. Mathieu-Daude, F., J. Welsh, T. Vogt, and M. McClelland. 1996. DNA rehybridization during PCR: the 'CoT effect' and its consequences. Nucleic Acids Res. 24:2080-2086.
43. Mattson, M. P., S. W. Barger, K. Furukawa, A. J. Bruce, T. Wyss-Coray, R. J. Mark, and L. Mucke. 1997. Cellular signaling roles of TGFβ, TNFα and β-APP in brain injury responses and in Alzheimer's disease. Brain Res. Rev. 23:47-61.
44. Meucci, O., A. Fatatis, A. A. Simen, T. J. Bushell, P. W. Gray, and R. J. Miller. 1998. Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity. Proc. Natl. Acad. Sci. USA 95:14500-14505.
45. Munger, J. S., C. Haass, C. A. Lemere, G.-P. Shi, W. S. F. Wong, D. B. Teplow, D. J. Selkoe, and H. A. Chapman. 1995. Lysosomal processing of amyloid precursor protein to Aβ peptides: a distinct role for cathepsin S. Biochem. J. 311:299-305.
46. Muramoto, T., T. Kitamoto, M. Z. Hoque, J. Tateishi, and I. Goto. 1993. Species barrier prevents an abnormal isoform of prion protein from accumulating in follicular dendritic cells of mice with Creutzfeldt-Jakob disease. J. Virol. 67:6808-6810.
47. Nagase, T., N. Seki, K. Ishikawa, A. Tanaka, and N. Nomura. 1996. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res. 3:17-24.
48. Peles, E., M. Nativ, M. Lustig, M. Grumet, J. Schilling, R. Martinez, G. D. Plowman, and J. Schlessinger. 1997. Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions. EMBO J. 16:978-988.
49. Peschon, J. J., J. L. Slack, P. Reddy, K. L. Stocking, S. W. Sunnarborg, D. C. Lee, W. E. Russell, B. J. Castner, R. S. Johnson, J. N. Fitzner, R. W. Boyce, N. Nelson, C. J. Kozlosky, M. F. Wolfson, C. T. Rauch, D. P. Ceretti, R. J. Paxton, C. J. March, and R. A. Black. 1998. An essential role for ectodomain shedding in mammalian development. Science 282:1281-1284.
50. Pesheva, P., G. Gennarini, C. Goridis, and M. Schachner. 1993. The F3/11 cell adhesion molecule mediates the repulsion of neurons by the extracellular matrix glycoprotein J1-160/180. Neuron 10:69-82.
51. Petanceska, S., P. Canoll, and L. A. Devi. 1996. Expression of rat cathepsin S in phagocytic cells. J. Biol. Chem. 271:4403-4409.
52. Pierre, P., and I. Mellman. 1998. Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells. Cell 93:1135-1145.
53. Prusiner, S. B., M. R. Scott, S. J. DeArmond, and F. E. Cohen. 1998. Prion protein biology. Cell 93:337-348.
54. Riesner, D., K. Kellings, K. Post, H. Wille, H. Serban, D. Groth, M. A. Baldwin, and S. B. Prusiner. 1996. Disruption of prion rods generates 10-nm spherical particles having high α-helical content and lacking scrapie infectivity. J. Virol. 70:1714-1722.
55. Schmidtmayerova, H., H. S. Nottet, G. Nuovo, T. Raabe, C. R. Flanagan, L. Dubrovsky, H. E. Gendelman, A. Cerami, M. Bukrinsky, and B. Sherry. 1996. Human immunodeficiency virus type 1 infection alters chemokine β peptide expression in human monocytes: implications for recruitment of leukocytes into brain and lymph nodes. Proc. Natl. Acad. Sci. USA 93:700-704.
56. Sklaviadis, T., A. Akowitz, E. E. Manuelidis, and L. Manuelidis. 1990. Nuclease treatment results in high specific purification of Creutzfeldt-Jakob disease infectivity with a density characteristic of nucleic acid-protein complexes. Arch. Virol. 112:215-228.
57. Sklaviadis, T., R. Dreyer, and L. Minuelidis. 1992. Analysis of Creutzfeldt-Jakob disease infectious fractions by gel permeation chromatography and sedimentation field flow fractionation. Virus Res. 26:241-254.
58. Vallat, A.-V., U. De Girolami, J. He, A. Mhashilkar, W. Marasco, B. Shi, F. Gray, J. Bell, C. Keohane, T. W. Smith, and D. Gabuzda. 1998. Localization of HIV-1 co-receplors CCR5 and CXCR4 in the brain of children with AIDS. Am. J. Pathol. 152:167-178.
59. Villadangos, J. A., R. J. Riese, C. Peters, H. A. Chapman, and H. L. Ploegh. 1997. Degradation of mouse invariant chain: roles of cathepsins S and D and the influence of major histocompatibility complex polymorphism. J. Exp. Med. 186:549-560.
60. von Eitzen, U., R. Egensperger, S. Kosel, E. M. Grasbon-Frodl, Y. Imai, K. Bise, S. Kohsaka. P. Mehraein, and M. B. Graeber. 1998. Microglia and the development of spongiform change in Creutzfeldt-Jakob disease. J. Neuropathol. Exp. Neurol. 57:246-256.
61. Wawer, C., H. Rüggeberg, G. Meyer, and G. Muyzer. 1995. A simple and rapid electrophoresis method to detect sequence variation in PCR-amplified DNA fragments. Nucleic Acids Res. 23:4928-4929.
62. Westmoreland, S. V., J. B. Rottman, K. C. Williams, A. A. Lackner, and V. G. Sasseville. 1998. Chemokine receptor expression on resident and inflammatory cells in the brain of macaques with simian immunodeficiency virus encephalitis. Am. J. Pathol. 152:659-665.
63. Williams, A., P. J. Lucassen, D. Ritchie, and M. Bruce. 1997. PrP deposition, microglial activation, and neuronal apoptosis in murine scrapie. Exp. Neurol. 144:433-438.
64. 2 and lipocortin-1 in the CNS during the incubation period of murine scrapie correlates with progressive PrP accumulations. Brain Res. 754:171-180.
65. Williams, A. E., A.-M. Van Dam, W. K. H. Man-A-Hing, F. Berkenbosch, P. Eikelenboom, and H. Fraser. 1994. Cytokines, prostaglandins, and lipocortin-1 are present in the brains of scrapie-infected mice. Brain Res. 654:200-206.
66. Wyss-Coray, T., E. Masliah, M. Mallory, L. McConlogue, K. Johnson-Wood, C. Lin, and L. Mucke. 1997. Amyloidogenic role of cytokine TGF-β1 in transgenic mice and in Alzheimer's disease. Nature 389:603-606.
67. Xi, Y.-G., L. Ingrosso, A. Ladogana, C. Masullo, and M. Pocchiari. 1992. Amphotericin B treatment dissociates in vivo replication of the scrapie agent from PrP accumulation. Nature 356:598-601.
68. Xia, M., S. Qin, L. Wu, C. R. Mackay, and B. T. Hyman. 1998. Immunohistochemical study of the β-chemokine receptors CCR3 and CCR5 and their ligands in normal and Alzheimer's disease brains. Am. J. Pathol. 153:31-37.
69. Zhang, L., T. He, A. Talal, G. Wang, S. S. Frankel, and D. D. Ho. 1998. In vivo distribution of the human immunodeficiency virus/simian immunodeficiency virus coreceptors: CXCR4, CCR3, and CCR5. J. Virol. 72:5035-5045.