Hes1 and Hes5 as notch effecters in mammalian neuronal differentiation

EMBO Journal

Volumn 18, Issue 8, 1999, Pages 2196-2207

  Ohtsuka, Toshiyuki ^a,b   Ishibashi, Makoto ^b,c,d   Gradwohl, Gérald ^e   Nakanishi, Shigetada ^b   Guillemot, François ^e   Kageyama, Ryoichiro ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY FACULTY OF MEDICINE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d HARVARD UNIVERSITY   (United States)

^e INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

bHLH; Hes1; Hes5; Neuronal differentiation; Notch

Indexed keywords

MEMBRANE PROTEIN;

ARTICLE; CARCINOGENESIS; EMBRYO; GENE EXPRESSION; MOUSE; NERVE CELL DIFFERENTIATION; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; STEM CELL;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CELLS, CULTURED; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; MICE; MUSCLE PROTEINS; NEURONS; RECEPTORS, NOTCH; RETROVIRIDAE;

EID: 0033561365     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (62)

1. Akazawa, C., Sasai, Y., Nakanishi, S. and Kageyama, R. (1992) Molecular characterization of a rat negative regulator with a basic helix-loop-helix structure predominantly expressed in the developing nervous system. J. Biol. Chem., 267, 21879-21885.
2. Akazawa, C., Isriibashi, M., Shimizu, C., Nakanishi, S. and Kageyama, R. (1995) A mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal is a positive transcriptional regulator expressed in the developing nervous system. J. Biol. Chem., 270, 8730-8738.
3. Artavanis-Tsakonas, S., Matsuno, K. and Fortini, M.E. (1995) Notch signaling. Science, 268, 225-232.
4. Bao, Z.-Z. and Cepko, C.L. (1997) The expression and function of Notch pathway genes in the developing rat eye. J. Neurosci., 17, 1425-1434.
5. Ben-Arie, N., Bellen, H.J., Armstrong, D.L., McCall, A.E., Gordadze, P.R., Guo, Q., Matzuk, M.M. and Zoghbi, H.Y. (1997) Math1 is essential for genesis of cerebellar granule neurons. Nature, 390, 169-172.
6. Blaumueller, C.M., Qi, H., Zagouras, P. and Artavanis-Tsakonas, S. (1997) Intracellular cleavage of notch leads to a heterodimeric receptor on the plasma membrane. Cell, 90, 281-291.
7. Capobianco, A.J., Zagouras, P., Blaumueller, C.M., Artavanis-Tsakonas, S. and Bishop, J.M. (1997) Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2. Mol. Cell Biol, 17, 6265-6273.
8. Casarosa, S., Fode, C. and Guillemot, F. (1999) Mash1 regulates neurogenesis in the ventral telencephalon. Development, 126, 525-534.
9. Cau, E., Gradwohl, G., Fode, C. and Guillemot, F. (1997) Mash1 activates a cascade of bHLH regulators in olfactory neuron progenitors. Development, 124, 1611-1621.
10. Chen, H., Thiagalingam, A., Chopra, H., Borges, M.W., Feder, J.N., Nelkin, B.D., Baylin, S.B. and Ball, D.W. (1997) Conservation of the Drosophila lateral inhibition pathway in human lung cancer: a hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression. Proc. Natl Acad. Sci. USA, 94, 5355-5360.
11. Conlon, R.A., Reaume, A.G. and Rossant, J. (1995) Notch1 is required for the coordinate segmentation of somites. Development, 121, 1533-1545.
12. de Angelis, M.H., McIntyre, J.,II and Gossler, A. (1997) Maintenance of somite borders in mice requires the Delta homologue Dll1. Nature, 386, 717-721.
13. de la Pompa, J.L. et al. (1997) Conservation of the Notch signalling pathway in mammalian neurogenesis. Development, 124, 1139-1148.
14. Dorsky, R.I., Chang, W.S., Rapaport, D.H. and Harris, W.A. (1997) Regulation of neuronal diversity in the Xenopus retina by Delta signalling. Nature, 385, 67-70.
15. Ellisen, L.W., Bird, J., West, D.C., Soreng, A.L., Reynolds, T.C., Smith, S.D. and Sklar, J. (1991) TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell, 66, 649-661.
16. Fode, C., Gradwohl, G., Morin, X., Dierich, A., LeMeur, M., Goridis, C. and Guillemot, F. (1998) The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons. Neuron, 20, 483-494.
17. Gridley, T. (1997) Notch signaling in vertebrate development and disease. Mol. Cell. Neurosci., 9, 103-108.
18. Guillemot, F., Lo, L.-C., Johnson, J.E., Auerbach, A., Anderson, D.J. and Joyner, A.L. (1993) Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomie neurons. Cell, 75, 463-476.
19. Honjo, T. (1996) The shortest path from the surface to the nucleus: RBP-J κ/Su(H) transcription factor. Genes Cells, 1, 1-9.
20. Hsieh, J.J.-D., Nofziger, D.E., Weinmaster, G. and Hayward, S.D. (1997) Epstein-Barr virus immortalization: Notch2 interacts with CBF1 and blocks differentiation. J. Virol., 71, 1938-1945.
21. Ishibashi, M., Moriyoshi, K., Sasai, Y., Shiota, K., Nakanishi, S. and Kageyama, R. (1994) Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system. EMBO J., 13, 1799-1805.
22. Ishibashi, M., Ang, S.-L., Shiota, K., Nakanishi, S., Kageyama, R. and Guillemot, F. (1995) Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis and severe neural tube defects. Genes Dev., 9, 3136-3148.
23. Issack, P.S. and Ziff, E.B. (1998) Genetic elements regulating HES-1 induction in Wnt-1-transformed PC12 cells. Cell Growth Differ., 9, 827-836.
24. Jarriault, S., Brou, C., Logeat, F., Schroeter, E.H., Kopan, R. and Israel, A. (1995) Signalling downstream of activated mammalian Notch. Nature, 377, 355-358.
25. Jarriault, S., Le Bail, O., Hirsinger, E., Pourquié, O., Logeat, F., Strong, C.F., Brou, C., Seidah, N.G. and Israël, A. (1998) Delta-1 activation of Notch-1 signaling results in HES-1 transactivation. Mol. Cell. Biol., 18, 7423-7431.
26. Jhappan, C., Gallahan, D., Stahle, C., Chu, E., Smith, G.H., Merlino, G. and Callahan, R. (1992) Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands. Genes Dev., 6, 345-355.
27. Johansson, C.B., Momma, S., Clarke, D.L., Risling, M., Lendahl, U. and Fisen, J. (1999) Identification of a neural stem cell in the adult mammalian central nervous system. Cell, 96, 25-34.
28. Joutel, A. et al. (1996) Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia. Nature, 383, 707-710.
29. Kageyama, R. and Nakanishi, S. (1997) Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system. Curr. Opin. Genet. Dev., 7, 659-665.
30. Kopan, R., Nye, J.S. and Weintraub, H. (1994) The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD. Development, 120, 2385-2396.
31. Kopan, R., Schroeter, E.H., Weintraub, H. and Nye, J.S. (1996) Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain. Proc. Natl Acad. Sci. USA, 93, 1683-1688.
32. Lecourtois, M. and Schweisguth, F. (1998) Indirect evidence for Delta-dependent intracellular processing of Notch in Drosophila embryos. Curr. Biol., 8, 771-774.
33. Lewis, J. (1996) Neurogenic genes and vertebrate neurogenesis. Curr. Opin. Neurobiol., 6, 3-10.
34. Logeat, F., Bessia, C., Brou, C., Le Bail, O., Jarriault, S., Seidah, N.G. and Israël, A. (1998) The Notch1 receptor is cleaved constitutively by a furin-like convertase. Proc. Natl Acad. Sci. USA, 95, 8108-8112.
35. Luo, B., Aster, J.C, Hasserjian, R.P., Kuo, F. and Sklar, J. (1997) Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor. Mol. Cell. Biol., 17, 6057-6067.
36. Ma, Q., Chen, Z., del Barco Barrantes, I., de la Pompa, J.L. and Anderson, D.J. (1998) neurogenin1 is essential for the determination of neuronal precursors for proximal cranial sensory ganglia. Neuron, 20, 469-482.
37. Matsuno, K., Eastman, D., Mitsiades, T., Quinn, A.M, Carcanciu, M.L., Ordentlich, P., Kadesch, T. and Artavanis-Tsakonas, S. (1998) Human deltex is a conserved regulator of Notch signalling. Nature Genet., 19, 74-78.
38. Milner, L.A., Bigas, A., Kopan, R., Brashem-Stein, C., Bernstein, I.D. and Martin, D.I.K. (1996) Inhibition of granulocytic differentiation by mNotch1. Proc. Natl Acad. Sci. USA, 93, 13014-13019.
39. Miyata, T. and Ogawa, M. (1994) Developmental potentials of early telencephalic neuroepithelial cells: a study with microexplant culture. Dev. Growth Differ., 36, 319-331.
40. Nishimura, M., Isaka, F., Ishibashi, M., Tomita, K., Tsuda, H., Nakanishi, S. and Kageyama, R. (1998) Structure, chromosomal locus and promoter of mouse Hes2 gene, a homologue of Drosophila hairy and Enhancer of split. Genomics, 49, 69-75.
41. Nye, J.S., Kopan, R. and Axel, R. (1994) An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells. Development, 120, 2421-2430.
42. Ordentlich, P., Lin, A., Shen, C.-P., Blaumueller, C., Matsuno, K., Artavanis-Tsakonas, S. and Kadesch, T. (1998) Notch inhibition of E47 supports the existence of a novel signaling pathway. Mol. Cell. Biol., 18, 2230-2239.
43. Pan, D. and Rubin, G.M. (1997) Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis. Cell, 90, 271-280.
44. Pear, W.S., Aster, J.C., Scott, M.L., Hasserjian, R.P., Soffer, B., Sklar, J. and Baltimore, D. (1996) Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J. Exp. Med., 183, 2283-2291.
45. Robey, E., Chang, D., Itano, A., Cado, D., Alexander, H., Lans, D., Weinmaster, G. and Salmon, P. (1996) An activated form of Notch influences the choice between CD4 and CD8 T cell lineages. Cell, 87, 483-492.
46. Sasai, Y., Kageyama, R., Tagawa, Y., Shigemoto, R. and Nakanishi, S. (1992) Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. Genes Dev., 6, 2620-2634.
47. Schroeter, E.H., Kisslinger, J.A. and Kopan, R. (1998) Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature, 393, 382-386.
48. Shawber, C., Nofziger, D., Hsieh, J.J.-D., Lindsell, C., Bogler, O., Hayward, D. and Weinmaster, G. (1996) Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway. Development, 122, 3765-3773.
49. Sommer, L., Shah, N., Rao, M. and Anderson, D.J. (1995) The cellular function of MASH1 in autonomie neurogenesis. Neuron, 15, 1245-1258.
50. Sparrow, J.R., Hicks, D. and Barnstable, C.J. (1990) Cell commitment and differentiation in explants of embryonic rat neural retina: comparison with the developmental potential of dissociated retina. Dev. Brain Res., 51, 69-84.
51. Struhl, G. and Adachi, A. (1998) Nuclear access and action of Notch in vivo. Cell, 93, 649-660.
52. Swiatek, P.J., Lindsell, C.E., del Amo, F.E., Weinmaster, G. and Gridley, T. (1994) Notch1 is essential for postimplantation development in mice. Genes Dev., 8, 707-719.
53. Takebayashi, K., Sasai, Y., Sakai, Y., Watanabe, T., Nakanishi, S. and Kageyama, R. (1994) Structure, chromosomal locus and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1: negative autoregulation through the multiple N box elements. J. Biol. Chem., 269, 5150-5156.
54. Takebayashi, K., Akazawa, C., Nakanishi, S. and Kageyama, R. (1995) Structure and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-5. J. Biol. Chem., 270, 1342-1349.
55. Tamura, K., Taniguchi, Y., Minoguchi, S., Sakai, T., Tun, T., Furukawa, T. and Honjo, T. (1995) Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-Jκ/Su(H). Curr. Biol., 5, 1416-1423.
56. Tomita, K., Ishibashi, M., Nakahara, K., Ang, S.-L., Nakanishi, S., Guillemot, F. and Kageyama, R. (1996a) Mammalian hairy and Enhancer of split homolog 1 regulates differentiation of retinal neurons and is essential for eye morphogenesis. Neuron, 16, 723-734.
57. Tomita, K., Nakanishi, S., Guillemot, F. and Kageyama, R. (1996b) Mash1 promotes neuronal differentiation in the retina. Genes Cells, 1, 765-774.
58. Tsuda, H., Takebayashi, K., Nakanishi, S. and Kageyama, R. (1998) Structure and promoter analysis of Math3 gene, a mouse homolog of Drosophila proneural gene atonal. J. Biol. Chem., 273, 6327-6333.
59. Turner, D.L. and Cepko, C.L. (1987) A common progenitor for neurons and glia persists in rat retina in development. Nature, 328, 131-136.
60. Wang, S., Sdrulla, A.D., diSibio, G., Bush, G., Nofziger, D., Hicks, C., Weinmaster, G. and Barres, B.A. (1998) Notch receptor activation inhibits oligodendrocyte differentiation. Neuron, 21, 63-75.
61. Weinmaster, G. (1997) The ins and outs of Notch signaling. Mol. Cell. Neurosci., 9, 91-102.
62. Yoshimatsu, T., Tamura, M., Kuriyama, S. and Ikenaka, K. (1998) Improvement of retroviral packaging cell lines by introducing the polyomavirus early region. Hum. Gene Ther., 20, 161-172.