Regulating a master regulator: Establishing tissue-specific gene expression in skeletal muscle

Epigenetics

Volumn 5, Issue 8, 2010, Pages 691-695

  Aziz, Arif ^a   Liu, Qi Cai ^a   Dilworth, F Jeffrey ^a,b  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Chromatin; Gene expression; Mef2; Muscle; MyoD; p38 MAPK; Six4; Transcription

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE 14; MYOCYTE ENHANCER FACTOR 2; MYOD PROTEIN; POLYCOMB GROUP PROTEIN; PROTEIN; PROTEIN MEF2D; PROTEIN SIX4; UNCLASSIFIED DRUG;

ARTICLE; GENE EXPRESSION REGULATION; GENE REPRESSION; NONHUMAN; PROMOTER REGION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TISSUE SPECIFICITY; TRANSCRIPTION INITIATION;

EID: 78149480527     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.5.8.13045     Document Type: Article

References (51)

1. Tapscott SJ. The circuitry of a master switch: Myodand the regulation of skeletal muscle gene transcrip-tion. Development 2005; 132:38-40.
2. Rudnicki MA, Schnegelsberg PN, Stead RH, BraunT, Arnold HH, Jaenisch R. MyoD or Myf-5 isrequired for the formation of skeletal muscle. Cell1993; 75:1351-9.
3. Davis RL, Weintraub H, Lassar AB. Expression ofa single transfected cDNA converts fibroblasts tomyoblasts. Cell 1987; 51:987-1000.
4. Weintraub H, Tapscott SJ, Davis RL, Thayer MJ,Adam MA, Lassar AB, et al. Activation of muscle-specific genes in pigment, nerve, fat, liver and fibro-blast cell lines by forced expression of MyoD. ProcNatl Acad Sci USA 1989; 86:5434-8.
5. Lassar AB, Davis RL, Wright WE, Kadesch T, MurreC, Voronova A, et al. Functional activity of myogenicHLH proteins requires heterooligomerization withE12/E47-like proteins in vivo. Cell 1991; 66:305-15.
6. Bergstrom DA, Penn BH, Strand A, Perry RL,Rudnicki MA, Tapscott SJ. Promoter-specific regu-lation of MyoD binding and signal transduction cooperate to pattern gene expression. Mol Cell 2002;9:587-600.
7. Penn BH, Bergstrom DA, Dilworth FJ, BengalE, Tapscott SJ. A MyoD-generated feed forwardcircuit temporally patterns gene expression duringskeletal muscle differentiation. Genes Dev 2004; 18:2348-53.
8. Murre C, McCaw PS, Vaessin H, Caudy M, Jan LY, Jan YN, et al. Interactions between heterologoushelix-loop-helix proteins generate complexes thatbind specifically to a common DNA sequence. Cell 1989; 58:537-44.
9. Blackwell TK, Weintraub H. Differences and simi-larities in DNA-binding preferences of MyoD andE2A protein complexes revealed by binding site selec-tion. Science 1990; 250:1104-10.
10. Blais A, Tsikitis M, Acosta-Alvear D, Sharan R,Kluger Y, Dynlacht BD. An initial blueprint for myo-genic differentiation. Genes Dev 2005; 19:553-69.
11. Cao Y, Yao Z, Sarkar D, Lawrence M, Sanchez GJ,Parker MH, et al. Genome-wide MyoD binding inskeletal muscle cells: a potential for broad cellularreprogramming. Dev Cell 2010; 18:662-74.
12. Davis RL, Weintraub H. Acquisition of myogen-ic specificity by replacement of three amino acidresidues from MyoD into E12. Science 1992; 256:1027-30.
13. Bengal E, Flores O, Rangarajan PN, Chen A, Weintraub H, Verma IM. Positive control mutationsin the MyoD basic region fail to show cooperativeDNA binding and transcriptional activation in vitro.Proc Natl Acad Sci USA 1994; 91:6221-5.
14. Dilworth FJ, Seaver KJ, Fishburn AL, Htet SL, Tapscott SJ. In vitro transcription system delineatesthe distinct roles of the coactivators pCAF and p300during MyoD/E47-dependent transactivation. ProcNatl Acad Sci USA 2004; 101:11593-8.
15. Puri PL, Sartorelli V, Yang XJ, Hamamori Y, Ogryzko VV, Howard BH, et al. Differential roles of p300 andPCAF acetyltransferases in muscle differentiation.Mol Cell 1997; 1:35-45.
16. Rampalli S, Li L, Mak E, Ge K, Brand M, Tapscott SJ, et al. p38 MAPK signaling regulates recruitmentof Ash2L-containing methyltransferase complexes tospecific genes during differentiation. Nat Struct MolBiol 2007; 14:1150-6.
17. Simone C, Forcales SV, Hill DA, Imbalzano AN, Latella L, Puri PL. p38 pathway targets SWI-SNFchromatin-remodeling complex to muscle-specificloci. Nat Genet 2004; 36:738-43.
18. Cao Y, Kumar RM, Penn BH, Berkes CA, Kooperberg C, Boyer LA, et al. Global and gene-specific analysesshow distinct roles for Myod and Myog at a commonset of promoters. EMBO J 2006; 25:502-11.
19. Sartorelli V, Puri PL, Hamamori Y, Ogryzko V, Chung G, Nakatani Y, et al. Acetylation of MyoDdirected by PCAF is necessary for the execution of the muscle program. Mol Cell 1999; 4:725-34.
20. Heller H, Bengal E. TFIID (TBP) stabilizes thebinding of MyoD to its DNA site at the promoterand MyoD facilitates the association of TFIIB withthe preinitiation complex. Nucleic Acids Res 1998;26:2112-9.
21. Deato MD, Marr MT, Sottero T, Inouye C, Hu P, Tjian R. MyoD targets TAF3/TRF3 to activate myo-genin transcription. Mol Cell 2008; 32:96-105.
22. de la Serna IL, Ohkawa Y, Berkes CA, Bergstrom DA, Dacwag CS, Tapscott SJ, et al. MyoD targetschromatin remodeling complexes to the myogeninlocus prior to forming a stable DNA-bound complex.Mol Cell Biol 2005; 25:3997-4009.
23. Li ZY, Yang J, Gao X, Lu JY, Zhang Y, Wang K, et al. Sequential recruitment of PCAF andBRG1 contributes to myogenin activation in12-O-tetradecanoylphorbol-13-acetate-induced earlydifferentiation of rhabdomyosarcoma-derived cells. JBiol Chem 2007; 282:18872-8.
24. Dacwag CS, Ohkawa Y, Pal S, Sif S, Imbalzano AN.The protein arginine methyltransferase Prmt5 isrequired for myogenesis because it facilitates ATP-dependent chromatin remodeling. Mol Cell Biol2007; 27:384-94.
25. Simone C, Stiegler P, Bagella L, Pucci B, Bellan C, De Falco G, et al. Activation of MyoD-dependenttranscription by cdk9/cyclin T2. Oncogene 2002;21:4137-48.
26. Giacinti C, Bagella L, Puri PL, Giordano A, Simone C. MyoD recruits the cdk9/cyclin T2 complex onmyogenic-genes regulatory regions. J Cell Physiol2006; 206:807-13.
27. Caretti G, Di Padova M, Micales B, Lyons GE, Sartorelli V. The Polycomb Ezh2 methyltransferaseregulates muscle gene expression and skeletal muscledifferentiation. Genes Dev 2004; 18:2627-38.
28. Seenundun S, Rampalli S, Liu QC, Aziz A, Palii C, Hong S, et al. UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis. EMBO J 2010; 29:1401-11.
29. Schwartz YB, Pirrotta V. Polycomb silencing mechanisms and the management of genomic programmes. Nat Rev Genet 2007; 8:9-22.
30. Schuettengruber B, Chourrout D, Vervoort M, Leblanc B, Cavalli G. Genome regulation by polycomb and trithorax proteins. Cell 2007; 128:735-45.
31. Pietersen AM, van Lohuizen M. Stem cell regulation by polycomb repressors: postponing commitment. Curr Opin Cell Biol 2008; 20:201-7.
32. Bracken AP, Dietrich N, Pasini D, Hansen KH, Helin K. Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev 2006; 20:1123-36.
33. Yee SP, Rigby PW. The regulation of myogenin gene expression during the embryonic development of the mouse. Genes Dev 1993; 7:1277-89.
34. Cheng TC, Wallace MC, Merlie JP, Olson EN. Separable regulatory elements governing myogenin transcription in mouse embryogenesis. Science 1993; 261:215-8.
35. Spitz F, Demignon J, Porteu A, Kahn A, Concordet JP, Daegelen D, et al. Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site. Proc Natl Acad Sci USA 1998; 95:14220-5.
36. Liu Y, Chu A, Chakroun I, Islam U, Blais A. Cooperation between myogenic regulatory factors and SIX family transcription factors is important for myoblast differentiation. Nucleic Acids Res 2010; In press.
37. Han J, Jiang Y, Li Z, Kravchenko VV, Ulevitch RJ. Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation. Nature 1997; 386:296-9.
38. Zetser A, Gredinger E, Bengal E. p38 mitogenactivated protein kinase pathway promotes skeletal muscle differentiation. Participation of the Mef2c transcription factor. J Biol Chem 1999; 274:5193-200.
39. de Angelis L, Zhao J, Andreucci JJ, Olson EN, Cossu G, McDermott JC. Regulation of vertebrate myotome development by the p38 MAP kinase-MEF2 signaling pathway. Dev Biol 2005; 283:171-9.
40. Perdiguero E, Ruiz-Bonilla V, Gresh L, Hui L, Ballestar E, Sousa-Victor P, et al. Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation. EMBO J 2007; 26:1245-56.
41. Brookes E, Pombo A. Modifications of RNA poly-merase II are pivotal in regulating gene expression states. EMBO Rep 2009; 10:1213-9.
42. Takaesu G, Kang JS, Bae GU, Yi MJ, Lee CM, Reddy EP, et al. Activation of p38alpha/beta MAPK in myogenesis via binding of the scaffold protein JLP to the cell surface protein Cdo. J Cell Biol 2006; 175:383-8.
43. Smith ER, Lee MG, Winter B, Droz NM, Eissenberg JC, Shiekhattar R, et al. Drosophila UTX is a histone H3 Lys27 demethylase that colocalizes with the elongating form of RNA polymerase II. Mol Cell Biol 2008; 28:1041-6.
44. Klymenko T, Muller J. The histone methyltransferases Trithorax and Ash1 prevent transcriptional silencing by Polycomb group proteins. EMBO Rep 2004; 5:373-7.
45. McKinnell IW, Ishibashi J, Le Grand F, Punch VG, Addicks GC, Greenblatt JF, et al. Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex. Nat Cell Biol 2008; 10:77-84.
46. Carvajal JJ, Keith A, Rigby PW. Global transcriptional regulation of the locus encoding the skeletal muscle determination genes Mrf4 and Myf5. Genes Dev 2008; 22:265-76.
47. Dahl JA, Collas P. MicroChIP-a rapid micro chromatin immunoprecipitation assay for small cell samples and biopsies. Nucleic Acids Res 2008; 36:15.
48. Meshorer E, Misteli T. Chromatin in pluripotent embryonic stem cells and differentiation. Nat Rev Mol Cell Biol 2006; 7:540-6.
49. Ragoczy T, Bender MA, Telling A, Byron R, Groudine M. The locus control region is required for association of the murine beta-globin locus with engaged transcription factories during erythroid maturation. Genes Dev 2006; 20:1447-57.
50. Meister P, Towbin BD, Pike BL, Ponti A, Gasser SM. The spatial dynamics of tissue-specific promoters during C. elegans development. Genes Dev 2010; 24:766-82.
51. Larsen BD, Rampalli S, Burns LE, Brunette S, Dilworth FJ, Megeney LA. Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks. Proc Natl Acad Sci USA 2010; 107:4230-5.